Streptomyces sp. RPA4-5: HEP86_03120
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Entry
HEP86_03120 CDS
T10325
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
srpa Streptomyces sp. RPA4-5
Pathway
srpa00270
Cysteine and methionine metabolism
srpa00450
Selenocompound metabolism
srpa01100
Metabolic pathways
srpa01110
Biosynthesis of secondary metabolites
srpa01230
Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:
srpa00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HEP86_03120 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
HEP86_03120 (metE)
Enzymes [BR:
srpa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
HEP86_03120 (metE)
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Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
B12-binding
Motif
Other DBs
NCBI-ProteinID:
QIY53650
UniProt:
A0A6H1JR66
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All DBs
Position
659435..661753
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AA seq
772 aa
AA seq
DB search
MTAKPAAAAARATVYGYPRQGQHRELKKAIEGYWKGRVAADTLLETAKDLRRSNWQQLAD
AGIHEVPTGDFSYYDHVLDTSVMVGAVPDRHRDAVAADALDGYFAMARGTQDVAPLEMTK
WFDTNYHYLVPELGPDTVFSADSGKQVAELKEALALGLAARPVLVGPVTYLLLSKPAPGV
AADFEPLTLLDRLLPVYAEVLADLRAAGAEWVQLDEPALVQDRTPAELNAAARAYRDLGT
LTDRPKLLVASYFDRLGDALPVLAKAPVDGLALDFTDAAAANLDALAAVGGLPGKRLVAG
VVNGRNIWINDLENSLATLGTLLGLADRVDVAASCSLLHVPLDAAVEREIDPQIARWLAF
AKQKTAELVTLARGLAQGTDTVAAELAANRADLASRATSALTHAPAVRARAAAVTDADGR
RSQPYAERAAAQRAHLGLPLLPTTTIGSFPQTAELRTARADLRTGRIDTAGYEERIRTEI
RDVLAFQEKAGIDVLVHGEPERNDMVQYFAEQLTGYLATQHGWVQSYGTRYVRPPVLAGD
ISRPEPMTVRWTRYAQSHTDRPVKGMLTGPVTMLAWSFVRDDQPLGDTARQVAFALRDEV
NDLEAAGTSVIQVDEPALRETLPLRAADHAAYLAWATEAFRLSTSGVQDRTQIHTHMCYA
EFGDIVQAIDDLDADVISLEAARSHMQVARELAAHGYPREAGPGVYDIHSPRVPSADEAA
ALLRKGLEAIPAERLWVNPDCGLKTRGWPETRASLENLVTAARTVRTELSGS
NT seq
2319 nt
NT seq
+upstream
nt +downstream
nt
gtgacagcgaagcccgcagccgcggcagcacgggccaccgtgtacggctacccccgccag
ggacagcaccgggaactgaagaaggccatcgaggggtactggaagggccgcgtcgccgcg
gacaccttgctggagaccgcgaaggacctgcgccgttcgaactggcagcaactggccgac
gccggcatccatgaggtgcccaccggtgacttctcgtactacgaccatgtgctggacacc
agcgtcatggtcggtgccgtcccggaccgtcaccgggacgccgtcgcggccgacgccctc
gacggctacttcgcgatggcgcgcggcacccaggacgtggcgccgctggaaatgaccaag
tggtttgacaccaactaccactacctggtgcccgagttgggcccggacaccgtcttcagc
gccgactccggcaagcaggtggccgagctgaaggaggccctcgcactcggcctcgctgcc
cggccggtgctcgtcgggccggtcacctatctgctgctgtcgaagcccgctcccggtgtc
gccgcggacttcgagccgctgaccctgctcgaccggctgctgccggtctacgccgaggtc
ctggccgatctgcgggccgccggtgccgagtgggtgcagctcgacgagcccgccctcgtc
caggaccgcacgccggccgagctgaacgccgccgcgcgcgcctaccgcgatctgggcacc
ctcaccgaccgcccgaagctcctggtcgcctcgtacttcgaccggctcggcgacgccctg
cccgtcctggccaaggctccggtggacggtctggcgctcgacttcaccgacgcggccgcg
gccaacctcgacgcgctggcggccgtcggcggactcccgggtaagcgcctggtggcgggc
gtggtcaacggccgcaacatctggatcaacgatctggagaactcgctggccaccctcggc
accctgctcggcctcgccgaccgggtcgatgtggccgcgtcctgctcgctgctgcatgtg
ccgctggacgccgcggtcgagcgcgagatcgacccgcagatcgcccgctggctggccttc
gccaagcagaagaccgcggagctggtgaccctggcacggggactggcgcagggcaccgac
accgtcgccgccgaactcgccgcgaaccgcgccgatctggcctcccgggccacgtccgcc
ctcacccacgccccggccgtacgcgcccgggcggcggccgtcaccgacgccgacggccgc
cgctcacagccgtacgccgagcgcgccgccgcccagcgcgcccacctcgggctgccgctg
ctgccgaccacgaccatcggctcgttcccgcagaccgccgagctgcgcacggcccgcgcc
gatctgcggaccggacggatcgacaccgccggctacgaggagcgcatcaggacggagatc
cgcgacgtcctcgccttccaggagaaggccggaatcgatgtcctcgtgcacggcgagccc
gagcgcaacgacatggtgcagtacttcgccgagcagctcaccggctacctcgccacccag
cacggctgggtgcagtcctacggaacccgctatgtccgcccgccggtcctggccggggac
atctcccgccccgagccgatgacggtccgctggacccggtacgcccagtcgcacaccgac
cgcccggtcaagggcatgctcaccggcccggtcaccatgctcgcctggtccttcgtccgc
gacgaccagccgctcggggacaccgcccgccaggtggcgttcgccctgcgcgacgaggtc
aatgacctggaggcagccggcacctcggtcatccaggtcgacgagcccgccctgcgcgag
acgctgccgctgcgcgcggccgaccacgccgcgtacctggcctgggccaccgaggcgttc
cgcctctccaccagcggggttcaggaccgcacccagatccacacccacatgtgctacgcc
gagttcggcgacatcgtgcaggccatcgacgacctcgacgcggacgtcatcagcctggag
gccgcccgctcccatatgcaggtagcccgcgagctcgccgcccacggctacccgcgcgag
gccggccccggtgtctacgacatccactccccgcgcgtcccgagcgccgacgaggcagcg
gccctgctgcgcaagggacttgaggccatccccgccgagcgtctctgggtcaacccggac
tgcggcctgaagacccgcggctggcccgagacccgcgcctcgctggagaacctggtcacc
gccgcccgtaccgtgcgaacggagctctccggctcctga
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