Streptomyces sp. RPA4-5: HEP86_08040
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Entry
HEP86_08040 CDS
T10325
Name
(GenBank) bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II
KO
K14652
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:
4.1.99.12
3.5.4.25
]
Organism
srpa Streptomyces sp. RPA4-5
Pathway
srpa00740
Riboflavin metabolism
srpa00790
Folate biosynthesis
srpa01100
Metabolic pathways
srpa01110
Biosynthesis of secondary metabolites
srpa01240
Biosynthesis of cofactors
Module
srpa_M00125
Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD
Brite
KEGG Orthology (KO) [BR:
srpa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00740 Riboflavin metabolism
HEP86_08040
00790 Folate biosynthesis
HEP86_08040
Enzymes [BR:
srpa01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.25 GTP cyclohydrolase II
HEP86_08040
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase
HEP86_08040
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Motif
Pfam:
DHBP_synthase
GTP_cyclohydro2
Motif
Other DBs
NCBI-ProteinID:
QIY54470
UniProt:
A0A6H1JTK4
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Position
complement(1784912..1786240)
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AA seq
442 aa
AA seq
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MTALQSWYDEDAAALALDPVAQAVADIAAGRPVVVVDDENRENEGDLVIAAEKATPEIIA
FMMSECRGLICAPMEGPELDRLELPQMVEHNTESMRTAFTVSVDATAAHGVTTGISAADR
ATTLRLLAAGESTAGDFVRPGHIFPLRARPGGVLVRNGHTEAGVDLARLAGLRPAAAIVE
IAGEDGTMLRLPELVPFARKHGLSIISIEDLIAYRQSSEPTVRREAETRLPTAHGEFTAY
GYRSTVDGVEHIALVAGDLGDGEDVLVRVHSECLTGDIFHSLRCDCGPQLEAAQRRIAEA
GRGVVIYLRGHEGRGIGLLSKLRAYELQERGRDTLDANLELGLPADSRDYAAGAQMLQDL
GVRSVRLMTNNPEKTAALVRHGLRVSGREAMPVQAGEHNLRYLRTKRDRMGHDLPWLDPA
AGGGADGAAYAPPASATTCDNQ
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcactacagagctggtacgacgaggacgccgcggccctggcgctggaccccgtc
gcacaggccgtcgccgatatcgccgccggccgccccgtggtcgtcgtggacgacgagaac
cgcgagaacgagggcgacctcgtcatcgccgcggagaaggccacccccgagatcatcgcg
ttcatgatgagcgagtgccgcgggctgatctgcgcccccatggagggcccggagctggac
cggctggaactcccgcagatggtcgagcacaacaccgagtcgatgcggaccgccttcacc
gtctccgtcgacgccaccgccgcgcacggcgtgaccaccggcatctccgccgccgaccgc
gccaccaccctgcggctgctcgccgccggggaatcgaccgccggtgacttcgtccggccc
ggccacatcttcccgctgcgcgcccggcccggcggggtgctggtccgcaacggccacacc
gaagccggcgtcgacctcgcccggctggccggactgcgcccggccgccgccatcgtggag
atcgccggcgaggacggcacgatgctgcggctgcccgagctggtgccgttcgcccgtaag
cacggactgtcgatcatctccatcgaggacctgatcgcctaccggcagtcgtccgagccc
accgtccgccgcgaggccgagacccggctgcccaccgcccacggcgagttcaccgcctac
ggctaccgctccaccgtcgacggcgtcgagcacatcgcgctggtcgccggggacctcggc
gacggcgaggacgtcctggtcagggtgcactccgaatgcctgaccggcgatatcttccac
tcgctgcgctgcgactgcggcccccagctggaggccgcgcagcggcggatcgccgaggcc
ggacgcggtgtggtgatctacctccgcggccatgagggacgcggtatcggcctgctgtcc
aagctgcgcgcctacgaactccaggagcgcggccgcgacaccctcgacgccaacctcgaa
ctggggctgcccgccgactcccgcgactacgcggccggcgcccagatgctccaggacctc
ggggtccgctcggtgcgcctgatgaccaacaacccggagaagaccgccgccctggtgcgg
cacggcctgcgggtctccggccgcgaggcgatgcccgtccaggccggggaacacaatctg
cggtatctgcgcaccaagcgggaccggatggggcacgacctgccctggctggaccccgcc
gcgggcggcggcgccgacggagcggcctacgccccgcccgcctcggccaccacctgcgac
aaccagtag
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