Streptomyces sp. RPA4-5: HEP86_15075
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Entry
HEP86_15075 CDS
T10325
Name
(GenBank) CoA-acylating methylmalonate-semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
srpa Streptomyces sp. RPA4-5
Pathway
srpa00280
Valine, leucine and isoleucine degradation
srpa00410
beta-Alanine metabolism
srpa00562
Inositol phosphate metabolism
srpa00640
Propanoate metabolism
srpa01100
Metabolic pathways
srpa01120
Microbial metabolism in diverse environments
srpa01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
srpa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
HEP86_15075
00562 Inositol phosphate metabolism
HEP86_15075
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
HEP86_15075
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
HEP86_15075
Enzymes [BR:
srpa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
HEP86_15075
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
HEP86_15075
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Motif
Pfam:
Aldedh
HBM
Motif
Other DBs
NCBI-ProteinID:
QIY55608
UniProt:
A0A6H1JPH9
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Position
complement(3340044..3341537)
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AA seq
497 aa
AA seq
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MKTLSHWIGGKPVEGVSGNFGPVYNPATGAQEKQVAFASADEVDAAVRAAKEAFRTWGSS
SLAKRTSVLFKYRELLDAHREEIAQLITAEHGKVHSDALGEVARGLEIVELACGIPEKLK
GELSTQVSTRVDVSSIRQSLGVVAGITPFNFPAMVPMWMFPLAIACGNTFVLKPSEKVPS
AALKLAELAAEAGLPDGVLNVVNGDKVAVDAILAHPDIAAVSFVGSTPIARYIHTTGTAN
GKRVQALGGAKNHMLVLPDADLDLAADSAINAAYGSAGERCMAISVVVAVGETADPLIGK
IKERADKLRIGPGDDPASEMGPLITKVHRDKVASYVTGAAAQGADVVIDGSGYTVEGYED
GHWMGVSLLDNVTPEMDAYRDEIFGPVLSVVRVETYDEAIALMNSSPWGNGTAIFTRDGG
AARRFQMEVEAGMVGVNVPIPVPVGYHSFGGWKDSLFGDHHIYGNDGVHFYTRGKVVTTR
WPDPSDGGINLGFPSNH
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atgaagaccctcagccactggatcggcggcaagcccgtcgagggcgtctccggcaacttc
ggcccggtctacaacccggccaccggcgcccaggagaagcaggtcgccttcgcctcggcc
gacgaggtggacgcggccgtccgcgcggccaaggaagccttccggacctggggcagcagc
tccctggccaagcgcacctcggtgctgttcaagtaccgcgagctgctcgacgcgcaccgc
gaggagatcgcgcagctgatcaccgccgagcacggcaaggtgcactccgacgcgctcggc
gaggtcgcccgcggtctggagatcgtggagctggcctgcggtatccccgagaagctcaag
ggcgagctgtccacccaggtctccacccgggtcgatgtctcctcgatccgccagtcgctc
ggtgtggtcgccggcatcacgccgttcaacttcccggcgatggtgccgatgtggatgttc
ccgctggccatcgcctgcggtaacaccttcgtcctcaagccgagcgagaaggtaccgagc
gccgccctcaagctcgccgagctggccgccgaggcggggctgcccgacggtgtactcaat
gtcgtcaacggcgacaaggtggccgtcgacgcgatcctggcgcacccggacatcgccgcg
gtctccttcgtcggctccacccccatcgcccgctacatccacaccaccggcaccgccaac
ggcaagcgggtgcaggcgctgggcggcgccaagaaccacatgctggtcctgccggacgcc
gacctggacctggccgcggactccgcgatcaacgccgcgtacggttcggccggtgagcgc
tgcatggcgatctccgtcgtggtggccgtcggcgagaccgccgacccgctgatcggcaag
atcaaggagcgcgccgacaagctgcggatcggccccggcgacgacccggcctccgagatg
ggcccgctgatcaccaaggtccaccgcgacaaggtcgcctcgtacgtcacgggtgccgcg
gcccagggcgccgatgtcgtcatcgacggcagcggctacaccgtcgagggctacgaggac
ggccactggatgggggtctccctcctggacaacgtcacgcccgagatggacgcctaccgc
gacgagatcttcggcccggtgctgtccgtggtccgcgtcgagacctacgacgaggccatc
gccctgatgaacagctcgccgtggggcaacggcaccgcgatcttcacccgggacggcggc
gcggcccgccgcttccagatggaggtcgaggccggcatggtcggcgtgaacgtgccgatc
ccggtgccggtcggctaccactccttcggtggctggaaggactcgctcttcggcgaccac
cacatctacggcaacgacggcgtgcacttctacacccgcggcaaggtcgtcaccacccgc
tggccggacccgtccgacggtggcatcaacctgggcttccccagcaaccactga
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