Streptomyces sp. RPA4-5: HEP86_20340
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Entry
HEP86_20340 CDS
T10325
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
srpa Streptomyces sp. RPA4-5
Pathway
srpa00280
Valine, leucine and isoleucine degradation
srpa00640
Propanoate metabolism
srpa00785
Lipoic acid metabolism
srpa01100
Metabolic pathways
srpa01110
Biosynthesis of secondary metabolites
srpa01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
srpa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
HEP86_20340 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
HEP86_20340 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HEP86_20340 (pdhA)
Enzymes [BR:
srpa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
HEP86_20340 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
QIY56448
UniProt:
A0A6H1JRY7
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Position
complement(4549340..4550557)
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AA seq
405 aa
AA seq
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MTVEGTAQRKNARGSSKRTTAKKATSAKKASPAKARNSGRPDEAEQDQLVQLLTPEGKRI
EHPDYSIDLSAEELRGLYRDMVLTRKFDAEATTLQRQGELGLWASLLGQEAAQIGSGRAL
RDDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNHGGWDPNSNNFHLYTIVIGSQTLHAT
GYAMGVQKDGADSAVIAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEK
QTRVPLYQRARGFGFPGVRVDGNDVLACLAVTKAALERARTGQGPMLIEAFTYRMGAHTT
SDDPTKYREDEERVAWEAKDPILRLRTYLEAEGLVDEAYLASIDEESEALGKRVRDAVRA
MPDPDDMAIFENVYADGHALVDEERAQFAAYQASFADADAAAEGN
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggaaggcactgcgcagcggaaaaacgcccgcggcagcagcaagcgcaccacc
gccaaaaaggcgacgtcggccaagaaggcgtccccggccaaggcccggaactccggccgg
cccgacgaggcggagcaggatcagctcgtacaactgctgacgcccgaaggcaagcggatc
gagcacccggattactcgatcgacctttccgccgaagagctgcgcggcctctaccgcgac
atggtgctgacgcggaagttcgatgccgaggcgaccaccctccagcgccagggcgaactg
ggcctgtgggcctcgctgctgggccaggaggccgctcagatcggctcgggccgcgcgctg
cgcgatgacgactacgtctttccgacctaccgcgagcacggcgtggcgtggtgccgcggc
gtcgacccgacgaacctgctgggcatgttccgcggggtcaatcacggcggctgggacccc
aacagcaacaacttccacctgtacacgatcgtcatcggttcgcagacgctgcacgcgacc
ggctatgcgatgggcgtgcagaaggacggcgcggattccgcggtcatcgcctatttcggt
gacggtgcttccagccagggagatgtcgcggaatccttcaccttctccgcggtctacaac
gccccggtcgtgttcttctgccagaacaaccagtgggcgatttccgaacccaccgagaag
cagacccgggtgccgctctaccagcgcgcccgcggattcggcttccccggcgtacgggtc
gacggcaatgacgtcctggcctgtctggcggtgaccaaggcggcgctggagcgggcgcgc
accggccagggtccgatgctgatcgaggcgttcacgtaccgcatgggtgcgcacaccacc
tccgacgacccgacgaagtaccgggaggacgaggagcgggtggcctgggaggccaaggac
ccgatcctgcggctgcggacgtacctggaggccgagggcctggtcgacgaggcgtacctc
gcgtcgatcgacgaggagagcgaggccctgggcaagcgggtccgcgatgccgtgcgtgcc
atgcccgacccggacgacatggcgatcttcgagaatgtctatgccgacgggcatgcgctc
gtcgatgaggagcgcgcgcagttcgccgcgtaccaggcgtcgttcgccgacgccgatgcc
gccgcggaggggaactga
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