Streptomyces sp. RPA4-5: HEP86_20980
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Entry
HEP86_20980 CDS
T10325
Symbol
thiC
Name
(GenBank) phosphomethylpyrimidine synthase ThiC
KO
K03147
phosphomethylpyrimidine synthase [EC:
4.1.99.17
]
Organism
srpa Streptomyces sp. RPA4-5
Pathway
srpa00730
Thiamine metabolism
srpa01100
Metabolic pathways
srpa01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
srpa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
HEP86_20980 (thiC)
Enzymes [BR:
srpa01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.17 phosphomethylpyrimidine synthase
HEP86_20980 (thiC)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
ThiC_Rad_SAM
ThiC-associated
Motif
Other DBs
NCBI-ProteinID:
QIY56559
UniProt:
A0A6H1JZT9
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Position
4686893..4688671
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AA seq
592 aa
AA seq
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MTLQDARTPENGANGGEEPQIGWHKGYVSGSRPDLRVPVRRVHLTNGKDVTLYDTSGPYT
DPNIDTDVRRGLAPLRENWIIGRGDTEEYAGRPMRPEDDGLKHTSPRGGLKNLDAVFPGR
PRQPRRGRAGAPVTQLAYAQRGEITAEMEYVAVREKVTPEFVRDEIAAGRAVLPVNINHP
EIEPMIIGKNFLVKVNANIGNSAVTSSIEEEVEKMTWATRWGADTVMDLSTGRNIHTTRE
WVLRNSPVPIGTVPLYQALEKVDGKAEELTWEIYKDTVIEQAEQGVDYMTVHAGVLLRYV
PLTARRKTGIVSRGGSIMAAWCLAHHQESFLYTHFEELCEILASYDVTYSLGDGLRPGSI
ADANDEAQFAELRTLGELNTIAKRHGVQTMIEGPGHVPMHKIKENIDLQQEICEEAPFYT
LGPLTTDIAPAYDHITSGIGAAMIAWWGTAMLCYVTPKEHLGLPDRDDVKTGVITYKIAA
HAADLAKGHPGAQEWDDALSDARFEFRWEDQFNLALDPDTARAFHDATLPAEPAKTAHFC
SMCGPKFCSMKISQDIRREHGGDLALDPEAGMAEKSKEFAAAGNRVYLPIAD
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atgactctgcaggatgcacgcacgcccgaaaacggtgccaacggtggcgaagagccgcag
atcggctggcacaagggctatgtctccggatcgcgccccgatcttcgggtgccggtccgg
cgggtgcacctcaccaacggcaaggacgtgacgctctacgacacgtcagggccgtacacc
gacccgaatatcgataccgacgtccgccgcggtctggcgccgctgcgggagaactggatc
atcggccgcggcgacaccgaggagtacgcgggccgccccatgcggccggaggacgacggc
ctcaagcacacctcgccgcgcggcggcctcaagaacctcgacgcggtcttcccgggccgt
ccccgccagccgcgccgcggccgtgcgggtgccccggtcacccagctcgcgtacgcccag
cgcggcgagatcaccgcggagatggagtacgtcgccgtccgcgagaaggtcacgcccgag
ttcgtccgcgacgagatcgcggccggccgcgcggtgctgccggtgaacatcaaccacccg
gagatcgagccgatgatcatcggcaagaacttcctggtgaaggtgaacgccaacatcggc
aattcggcggtcacttcctccatcgaggaggaggtggagaagatgacctgggcgacccgc
tggggcgccgacacggtgatggatctgtccaccggccgcaatatccacaccacccgcgag
tgggtactgcgcaactcccccgtccccatcggcaccgtccccctctaccaggcgctggag
aaggtcgacggcaaggccgaggaactgacctgggagatctacaaggacaccgtcatcgag
caggcggaacagggcgtcgactacatgacggtgcacgccggtgtgctgctccgctatgtg
ccgctcacggcccgccgtaagaccggcatcgtctcccgcggcggttcgatcatggccgcc
tggtgcctggcccaccatcaggagtcgttcctctacacgcacttcgaggagctctgcgag
attctcgcctcctacgacgtcacctactcgctcggtgacggtctgcgccccggctccatc
gcggacgccaacgacgaggcgcagttcgcggagctgcggacgctcggtgagctgaacacc
atcgccaagcggcacggcgtccagaccatgatcgagggcccggggcatgtcccgatgcac
aagatcaaggagaacatcgacctccagcaggagatctgcgaagaggcgccgttctacacg
ctcggcccgctgacgaccgacatcgcgcccgcctacgaccacatcacctccggtatcggc
gcggcgatgatcgcgtggtggggcaccgcgatgctctgctacgtcacgcccaaggagcac
ctgggcctgccggaccgcgacgacgtcaagaccggcgtcatcacgtacaagatcgcggcc
catgcggcagacctggccaagggccacccgggcgcccaggaatgggatgacgcgctctcc
gacgcccgcttcgagttccgctgggaggaccagttcaacctggccctcgacccggacacg
gcccgcgccttccatgacgcgacgctgcccgccgaaccggcgaagacggcccacttctgc
tcgatgtgcggcccgaagttctgctcgatgaagatcagccaggacatccgccgggaacac
ggtggcgacctggccctcgaccccgaggccggaatggccgagaagtcgaaggagttcgcg
gcggcgggcaaccgcgtgtatctcccgatcgcggactag
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