Streptomyces sp. RPA4-5: HEP86_24990
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Entry
HEP86_24990 CDS
T10325
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
srpa Streptomyces sp. RPA4-5
Pathway
srpa00230
Purine metabolism
srpa00670
One carbon pool by folate
srpa01100
Metabolic pathways
srpa01110
Biosynthesis of secondary metabolites
Module
srpa_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
srpa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
HEP86_24990 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
HEP86_24990 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
srpa04147
]
HEP86_24990 (purH)
Enzymes [BR:
srpa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
HEP86_24990 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
HEP86_24990 (purH)
Exosome [BR:
srpa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
HEP86_24990 (purH)
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
QIY57185
UniProt:
A0A6H1K5Y5
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All DBs
Position
5582702..5584261
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AA seq
519 aa
AA seq
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MTVTEGTKRPIRRALVSVYDKSGLEELAQGLHAAGVQLVSTGSTAAKIAAAGVPVTKVEE
LTGFPECLDGRVKTLHPKVHAGILADLRLEDHRQQLAGLGVEPFDLVIVNLYPFRETVAS
GATPDECVEQIDIGGPSMVRAAAKNHPSVAVVVNPAHYGEVLKAVADGGFALDGRKRLAA
EAFQHTAAYDVAVASWFLDGYADDATFPEFLGATYSRKNVLRYGENPHQGAALYVDGSGG
LAEAEQLHGKEMSYNNYTDTDAARRAAYDHSEPCVAIIKHANPCGIAVAADVAEAHRNAH
ACDPLSAFGGVIAVNRPVTVAMAEQVAEIFTEVIVAPGYEDGAVEILARKKNIRVLRCPE
APSNPVEVKPVDGGALLQVTDRLQAEGDDPANWTLASGDALPAAELAELAFAWRACRAVK
SNAILLAKDGATVGVGMGQVNRVDSAKLAVQRAGEERARGSYAASDAFFPFPDGFEMLAE
AGVKAVAQPGGSVRDEQVVEAARKAGVTMYFTGTRHFFH
NT seq
1560 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtcaccgaaggcacgaagcggcccatccgccgcgcgctggtcagcgtctacgac
aagtccgggctggaggagctggcgcagggcctgcacgcggcgggcgtccagctggtctcc
accggatcgacggccgcgaagatcgctgcggccggggtgccggtcaccaaggtcgaggag
ctgacgggcttccccgagtgcctcgacggccgggtcaagaccctgcacccgaaggtgcac
gccggcatcctggccgacctccgcctggaggaccaccgtcagcagctggccgggctcggc
gtcgagccgttcgacctggtcatcgtcaacctctacccgttccgggagaccgtggcctcc
ggcgccacccccgacgagtgtgtggagcagatcgacatcggcggcccctccatggtccgc
gccgccgccaagaaccacccgtcggtcgccgtcgtcgtcaaccccgcccactacggcgag
gtcctcaaggccgtcgctgacggcggcttcgcgctggacgggcgcaagcggctggcggcg
gaggccttccagcacaccgcggcctacgacgtggcggtcgcctcctggttcctcgacggc
tacgcggatgacgcgacgttccccgagttcctcggcgccacctactcccgcaagaacgtc
ctgcgctacggcgagaacccgcaccagggcgccgcgctgtacgtggacggcagcggcggg
ctcgcggaggccgagcagctgcacggcaaggagatgtcgtacaacaactacacggacacc
gacgccgcgcgccgggccgcgtacgaccacagcgagccctgcgtcgcgatcatcaagcac
gccaacccgtgcggtatcgcggtcgccgcggatgtcgccgaggcgcaccgcaacgcgcac
gcctgtgacccgctgtccgccttcggcggcgtcatcgccgtcaaccgcccggtcaccgtg
gcgatggccgagcaggtcgccgagatcttcaccgaggtcatcgtggcccccggctacgag
gacggcgcggtcgagatcctcgcccgcaagaagaacatccgggtgctgcgctgccccgag
gcgccgtcgaaccccgtagaggtcaagccggttgacggcggtgcgctgctccaggtcacc
gaccgcctccaggccgagggcgacgatccggcgaactggacgctggccagcggcgacgcg
ctgcccgccgcggaactggccgagctggccttcgcctggcgggcctgccgtgccgtcaag
tccaacgcgatcctgctcgccaaggacggcgccacggtcggcgtcggcatgggtcaggtc
aaccgcgtcgactccgcgaagctcgcggtgcagcgtgcgggcgaggagcgggcgcggggc
tcctacgccgcctccgacgccttcttcccgttcccggacggcttcgagatgctggccgag
gccggcgtcaaggccgtggcccagcccggtggttcggtccgcgacgagcaggtcgtcgag
gccgcgcggaaggccggcgtgacgatgtacttcacgggcacccggcacttcttccactga
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