Streptomyces sp. RPA4-2: HEP85_21350
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Entry
HEP85_21350 CDS
T10422
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
srpz Streptomyces sp. RPA4-2
Pathway
srpz00280
Valine, leucine and isoleucine degradation
srpz00640
Propanoate metabolism
srpz00785
Lipoic acid metabolism
srpz01100
Metabolic pathways
srpz01110
Biosynthesis of secondary metabolites
srpz01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
srpz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
HEP85_21350 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
HEP85_21350 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HEP85_21350 (pdhA)
Enzymes [BR:
srpz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
HEP85_21350 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
QIY63703
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All DBs
Position
4838281..4839447
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AA seq
388 aa
AA seq
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MTVMEQRGAYRPTPPPAWQPRTDPAPLLPDALPHRVLGTEAAAQVDPDLLRRLYTELVRG
RRYNTQATALTKQGRLAVYPSSTGQEACEVAAALVLEERDWLFPSYRDTLAAVARGLDPV
QALTLLRGDWHTGYDPREHRIAPLCTPLATQLPHAVGLAHAARLKGDDVVALALVGDGGT
SEGDFHEALNFAAVWQAPVVFLVQNNGFAISVPLDKQTAAPSLAHKAVGYGMPGRLVDGN
DAAAVHEVLSDAVRHARAGGGPTLVEAVTYRIEAHTNADDATRYRGDSEVETWRAHDPIV
LLEQELTERGLLDEEGIQAAREAAETMAADLRARMNQDPVLDPMDLFAHVYAEPTPQLRE
QEAQLRAELAAEAEPDSAAGSESEGRGR
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
atgacggtcatggagcagcgaggtgcttaccggcccacgccgccgcccgcctggcagccc
cgcaccgaccccgcgccgctgctgcccgacgcgctgccccatcgcgtcctcggcaccgaa
gcggccgcacaggtcgacccggatctgctgcgccgtctgtacacggagctggtgcgaggc
cgccgctacaacacgcaggccacggctctcaccaagcagggccgcctcgcggtctacccc
tccagcacgggccaggaggcctgtgaggtcgccgccgcgctcgtcctggaggagcgcgac
tggctcttccccagctaccgcgacaccctcgccgccgtcgcccgcggcctcgaccccgtc
caggccctgaccctcctgcgcggcgactggcacaccgggtacgacccccgcgagcaccgc
atcgcccccctgtgcaccccgctcgccacccagctcccgcacgcggtgggcctcgcgcac
gccgcccggctcaagggtgacgacgtggtcgcgctcgccctggtgggcgacggcggcacc
agcgagggcgacttccacgaggcgctgaacttcgccgccgtgtggcaggccccggtcgtc
ttcctcgtccagaacaacggcttcgccatctccgtcccgctcgacaagcagaccgcggct
ccgtcgctggcccacaaggccgtcggctacggaatgcccgggcgcctggtcgacgggaac
gacgcggcggccgtgcacgaggtcctgagcgacgccgtgcgccacgcgcgcgcgggcggc
ggcccgacgctcgtcgaggccgtgacgtaccgcatcgaggcccatacgaacgccgacgac
gccacccgctaccgcggcgactccgaggtcgagacctggcgcgcgcacgacccgatcgtg
ctcctggagcaggagctgaccgagcgcggtctcctcgacgaggagggcatacaggccgcc
cgtgaggccgccgagacgatggccgcggacctgcgcgcccggatgaaccaggacccggtg
ctcgaccccatggacctgttcgcccatgtgtatgccgagcccacaccgcaactgcgcgaa
caggaagcgcagttgcgtgcggagctggcggccgaggccgagccggactccgccgccgga
tccgagtcggaaggcaggggccgatga
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