Streptomyces sp. RPA4-2: HEP85_28385
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Entry
HEP85_28385 CDS
T10422
Name
(GenBank) D-alanine--D-alanine ligase family protein
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
srpz Streptomyces sp. RPA4-2
Pathway
srpz00470
D-Amino acid metabolism
srpz00550
Peptidoglycan biosynthesis
srpz01100
Metabolic pathways
srpz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
srpz00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
HEP85_28385
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HEP85_28385
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HEP85_28385
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
srpz01011
]
HEP85_28385
Enzymes [BR:
srpz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
HEP85_28385
Peptidoglycan biosynthesis and degradation proteins [BR:
srpz01011
]
Precursor biosynthesis
Amino acid ligase
HEP85_28385
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
QIY64818
LinkDB
All DBs
Position
6402204..6403361
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AA seq
385 aa
AA seq
DB search
MSTENLPQSPEQAPRKPRVAVVFGGRSSEHGISVVTAGAVLRAIDRTKYDVLPIGITLDG
RWALTADEPERMAIVDRQQPSVDLLAESDEGAVILPVDPSNREVVYSEPGSVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKEYMKRVFTSFGLKVGPYTV
IRPREWELDPAGARKRIAEFAGEHGWPLFIKPARAGSSFGITKVDSFEGLEEAFEEARRH
DPKIIVEALLRGREIECGVLEFEDGPRASVPAEIPPVQSHDFYDFEAKYIDSAPGIVPAP
LTEEQTAEVRRLAVEAFDAASCEGLVRADFFLTEDGEFVINEINTMPGFTPISMYPRMWE
ETGVGYPELVDLLVQAALRRSTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccgagaacctcccccagagccctgagcaggcgcctcgcaagccgcgcgtggcc
gtcgtcttcggcgggcgcagctccgaacacgggatctccgtggtcacggccggcgccgtc
ctgcgcgccatcgaccgtacgaagtacgacgtcctgccgatcggcatcaccctggacggc
cgttgggcgctcaccgccgacgagccggagcggatggccatcgtcgaccggcagcagccc
agcgtggacctcctcgcggagtcggacgagggcgccgtgatcctgcccgtcgacccgtcc
aaccgcgaagtcgtctacagcgagcccggatccgtccccaaggccctgggcgaggtcgac
gtcgtcttccccgtgctgcacggcccgtacggcgaggacggcacgctccagggcctcctg
gagctctccggggtcccgtacgtcggctcgggcgtgctcgcctcggccgtcggccaggac
aaggagtacatgaagcgggtcttcacctccttcgggctgaaggtgggcccgtacacggtg
atccgtccccgggagtgggagctcgacccggccggcgcccgcaagcggatcgcggagttc
gcgggggagcacggctggccgctgttcatcaagcccgcccgcgccggctcctcgttcggc
atcaccaaggtcgactccttcgaaggtctcgaggaggccttcgaggaggcccggcgccac
gacccgaagatcatcgtggaggcgctgctgcgcggccgtgagatcgagtgcggggtcctc
gagttcgaggacggcccgcgcgccagcgtgccggccgagatcccgccggtgcagtcccac
gacttctacgacttcgaggcgaagtacatcgactcggccccgggcatcgtgcccgcgccg
ctcaccgaggagcagaccgccgaggtgcggcgcctggcggtcgaggccttcgacgcggcg
tcgtgcgagggtctcgtccgcgcggacttcttcctcaccgaggacggtgagttcgtgatc
aacgagatcaacacgatgccgggcttcacgccgatctccatgtacccgcggatgtgggag
gagaccggggtcggctacccggagctggtcgacctcctggtgcaggcggcgctgcggcgc
tccacgggcctgcgctag
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