Streptomyces sp. RPA4-2: HEP85_34295
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Entry
HEP85_34295 CDS
T10422
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
srpz Streptomyces sp. RPA4-2
Pathway
srpz00270
Cysteine and methionine metabolism
srpz00480
Glutathione metabolism
srpz01100
Metabolic pathways
srpz01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
srpz00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HEP85_34295 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
HEP85_34295 (egtA)
Enzymes [BR:
srpz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
HEP85_34295 (egtA)
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Motif
Pfam:
GCS2
Helicase_C_3
Motif
Other DBs
NCBI-ProteinID:
QIY65722
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All DBs
Position
complement(7801792..7803150)
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AA seq
452 aa
AA seq
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MSDSVSDCTEQRSAVTEAEVEALVRGICFKTGPPRTLGVEVEWLVHELRRPQLPATPEQL
EAAYAALRTLSLRSALTVEPGGQLELSSAPAGSLMECIGSVSADLDAVRAVLREAGLGLS
GNGHEPWNPPSRYLREPRYDAMERYLDRTGPEGRAMMCSSASVQVCLDAGYEEPGPLGHG
RRWWLANQLGAVLVAAFAHSPLARGHYTGWRSTRQSLWTAMDPGRSAAPPLGGDPRAAWA
RHVLDAPVMCVRAPEGPWEVPEGLTFREWTRSGTPPNRADLDYHLTTLFPPVRPRGHLEL
RMIDAQPGEDGWIVPLAVTAALFDDPEAAEIAYRTVKPLAERAEGLPAPSNPLWIGAARH
GLTDPELREAAVICFAAAAEALPRLGATAEVREAVAEFTDRYVARGRCPADDLLSQFHSQ
FHGRLHDRPHDRPQDRSDDRSQNRSHGKDIRT
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgtccgattcggtgagtgactgtacggagcaacgctccgccgtcaccgaggccgaggtg
gaagcgctggtccgaggcatatgcttcaagaccggccctccccgcaccctcggtgtcgaa
gtggaatggctcgtccacgagctgcggcggccgcagctccccgcaacaccagaacagctc
gaagcggcgtacgccgctctgcggaccctgtccctgcgttcggcgctcaccgtcgaaccg
ggcggccagctggagctcagctccgcacccgccggctccctgatggagtgcatcgggtcc
gtgtcggccgatctcgacgcggtgcgcgcggtactgcgcgaggccggactgggcctcagt
ggcaacggccacgaaccctggaaccccccgagccgctacctccgtgagccgcgctacgac
gccatggagcgctacctggaccgcacgggccccgagggccgggcgatgatgtgctcctcc
gcctcggtccaggtgtgcctggacgccgggtacgaggagcccggaccgctcggccacggg
cgccgctggtggctggcgaaccagttgggcgcggtcctggtggccgcgttcgcgcactcc
ccgctcgcccggggccactacaccggctggcgctccacgcggcagtcgctgtggacggcc
atggacccgggccggtccgccgcgcctccgctgggcggcgatccgcgcgccgcctgggcc
cggcacgtcctggacgcgccggtgatgtgcgtccgtgcgccggagggcccctgggaggta
cccgagggcctgaccttccgggagtggacccggtccggcacaccgccgaaccgggcggat
ctggactaccacctcacgaccctgttcccgccggtccgcccccgcggccatctggaactg
cgcatgatcgacgcgcagccgggcgaggacgggtggatcgtgccactggcggtgacggca
gcgctgttcgacgacccggaggcggcggagatcgcctaccggaccgtcaagcccctcgcg
gagcgggcggaaggactgccggctccgtccaatccgctgtggatcggcgccgcccggcac
ggcctgaccgaccccgagctgcgcgaggccgccgtcatctgcttcgcggccgccgccgag
gcgctgccccgcctcggtgccaccgccgaggtgcgggaggccgtcgcggagttcacggac
cgctatgtggcccgggggcgctgccccgccgacgatctgctgagccagttccacagtcaa
ttccacggtcggctccacgaccgtccccacgaccggccccaggatcggtccgacgaccgg
tcccagaatcggtcccacgggaaggacatccgcacatga
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