Streptomyces sp. RPA4-2: HEP85_37220
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Entry
HEP85_37220 CDS
T10422
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
srpz Streptomyces sp. RPA4-2
Pathway
srpz00280
Valine, leucine and isoleucine degradation
srpz00640
Propanoate metabolism
srpz00785
Lipoic acid metabolism
srpz01100
Metabolic pathways
srpz01110
Biosynthesis of secondary metabolites
srpz01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
srpz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
HEP85_37220
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
HEP85_37220
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HEP85_37220
Enzymes [BR:
srpz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
HEP85_37220
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Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
QIY66169
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Position
8472284..8474467
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AA seq
727 aa
AA seq
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MPTHVNLAAASPWVSLTASTEDWDAAEPDVLLRMLAQAQWIRVFEEYVLELASQGLVHGP
AHSSIGQEGGAVGSILPLRSDDYVNGSHRGHHQFLAKAFGHVAVPKSGTLPELTDDIRTV
LRRTLAEICGLAEGYCCGRGGSMHLRWREAGAMGTNAIVGGGVPQAAGFAFNQRRSGSDA
VTVTYFGDGAANIGSVLETLNLAAVWRLPVCFFIENNQYAVSTSVSESTAEPRLSARGLG
FDIPSWRVDGMDPLAVNLAMNEALAHMRAGNGPTIVEADLYRYFHQNGPYPGSSFGYRDK
SEEQAWRDRDPVELLRTQAVRRGLATEEHVTAARDEIVATMREIGNALLEPVPGGKPGQR
RIKASEWPDPGFVDVGVRGDLSELADSRFEEADTFSGQLGERRFIDVVSDVIGRRMETDE
RVVVLGEDVHRLKGGTNGATKRAIEVAPDRVLGTPICENAFTGLGCGIAVDGRFRPIVEY
MYADFMWVAADQLFNQVAKARHMFGGEIPVPFVLRSKLAAGTGYGSQHSMDPAGILTTAP
GLRVIAPSNPFDYVGLMNTALACEDPVVVLEHVDLYTATGIGPVSDLDYRIPVGKAALRS
EGDDLTVISYLSMVGHSLAALEQVPEVKADLIDLRWLDRASIDWETIERSVKKTNRVLIV
EQGAIGTSYGSWLADEIHRRLFDWLDAPVERVTGKVSSPSISKVLERAAVARTEEVVAAL
RGIAAAI
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccatgtgaacctggccgcagcttccccgtgggtcagtctgaccgcgtcgacc
gaggactgggacgcggcggagcccgatgtgctgctgcggatgctggcccaagcgcagtgg
atccgcgtgttcgaggagtatgtgctcgaactggcgagccagggtctcgtgcacggcccg
gcgcactcgagcatcggccaggagggcggggccgtcggctcgatcctgcccctgcgtagc
gacgactacgtcaacggctcacaccgaggccaccaccagttcctggccaaggcgttcgga
cacgtcgcggtgcccaagtccgggactctgcccgagctcaccgacgacatacgaaccgtg
ctccggcgcaccctcgcggagatctgcggcctggccgaggggtactgctgcggccggggt
ggctcgatgcacctgcgctggcgggaagccggcgccatgggcaccaacgcgatcgtcggt
ggcggtgtgccgcaggcagcgggcttcgcgttcaaccaacgcagatccggctccgatgcc
gtgaccgtcacctatttcggcgacggcgcggccaacatcggatccgttctggagaccctc
aacctcgcggcagtgtggcgactgccggtctgcttcttcatcgagaacaaccagtacgcg
gtgtcgacgtcggtgtcggagtccaccgccgaaccacgtctgtccgcgcgtggcctcggg
ttcgacataccgagctggcgggtcgacggaatggatccactcgccgtcaacctggccatg
aacgaggcgctcgcgcacatgcgggcgggcaatgggccgaccatcgtcgaggccgacctg
taccggtacttccaccagaacggaccgtacccgggcagctccttcggttaccgcgacaag
tccgaggagcaggcttggcgggaccgggatccggtcgagctgctgcgcacccaggccgtc
cggcgcggcctggccaccgaggagcacgtgaccgcggcgcgggacgagatcgtcgcgacc
atgcgggagatcggcaacgcgctgctggaacccgtcccgggcggcaagccgggacagcgt
cggatcaaggcgagcgagtggcccgaccccgggttcgtcgacgtcggtgtacgtggcgac
ctgagcgagctcgccgacagccgctttgaggaggccgacacgttctccggacaactcggc
gagcgccggttcatcgacgtggtcagcgacgtcatcggccgtcgcatggagaccgatgag
cgcgtcgtcgtgctcggtgaggacgtgcaccgcctcaagggcggcaccaacggcgccacc
aagcgtgcgatcgaggtcgcaccggaccgcgtgctgggcacgccgatctgcgagaacgcc
ttcacgggcctaggctgtggcatcgcggtggacgggcggttccggccgatcgtggagtac
atgtacgcggacttcatgtgggtcgccgccgaccagttgttcaaccaggtcgccaaggca
cgccacatgttcggcggcgagatccccgtgccgttcgtactgcgctccaaactcgccgcg
ggtaccggctacgggtcgcagcactcgatggacccggcgggcattctcaccacggcgccg
ggactgcgggtgatcgcaccctccaacccgttcgactacgtgggcctgatgaacacggca
ctcgcctgcgaggaccctgtggtcgtcctggagcacgtcgacctctacacggcgaccggc
atcggaccggtgtccgacctggactaccggatcccggtggggaaggcggcgctacgcagt
gagggcgacgacctcaccgtgatctcgtacctgtcgatggtcgggcacagcctggcggcg
ctcgaacaggtaccggaggtcaaggccgatctcatcgacctacggtggctggaccgggcg
agcatcgactgggagaccatcgaacgcagcgtcaagaagaccaaccgcgtgttgatcgtc
gagcagggtgccatcggcacgtcctacggttcctggctggccgacgagatccaccggcga
ctgttcgactggctggacgcgccggtcgagcgggtaaccggcaaggtctcctctcccagc
atcagcaaggtactcgaacgtgccgcggtcgcgcgcaccgaggaagtcgtcgccgccctg
cgcggcatcgccgccgccatttga
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