Streptomyces sp. RPA4-2: HEP85_43740 Help Entry HEP85_43740       CDS       T10422                                  Name (GenBank) type I polyketide synthase Organism srpz  Streptomyces sp. RPA4-2 SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Acyl_transf_1 ketoacyl-synt KR Ketoacyl-synt_C PKS_DH_N PS-DH PP-binding KAsynt_C_assoc CurL-like_PKS_C adh_short SpnB_Rossmann ADH_zinc_N_2 RhiE-like_linker Epimerase Thiolase_N PKS_DE ADH_zinc_N ADH_N GDP_Man_Dehyd NmrA SDR ACP_syn_III Polysacc_synt_2 Motif Other DBs NCBI-ProteinID:  XDO60611 LinkDB All DBs Position complement(184094..197893) Genome browser AA seq 4599 aa AA seqDB search MSARSAAALREQAARLLAHVEEHPALDTADIAHALVTTRPGFEHRAVVRGTARTGLLRGL AAVAAGEPSPDAVTGDTLTEGTTAFLFAGQGTQRPGMGRELYDAFPVYADAFDAVCGHFE GRLEQPLREVVLGDDAALLDRTEYAQPALFAVEVALYRLVESWGVRPHHLLGHSVGELAA AHVAGVLTLPDACRLVAARGRLMQALPEGGAMIALQATEEEVLPLLAGREDEIGLAALNG PRSVVVAGDEPAVLAVAAHFAGQGRKTTRLRVSHAFHSPRMEPMLADFRAVAESIGYAEP RIPVVSDLTGRPAEAGELTSPEYWVRHVRQAVRFADGIAWLEHHGVEHCLELGPDATLTT LAQGCWESHGHLTVPALRADRPEPAVLLAALGALFTRGVPVDWQSCLDAAAPGGRPVPLP TYAFQHRTFWLDVPTGSGDPAAAGLLDADHPLLSAVVPPAEGATVVLTGRLSAHAQPWLA AHRVNGSVVVPSTAFLELALRAGAHTDCGHVRELVLESPLVLPEHGRVHLQIRVAEPDAL GSRVFGVYGRPENLNNPDNLNAAGPWTRHAGGLLSTRHPERTTGAPEFDFTAWPPPGAEP LDVDGVYERLAAAGLDYGPVFQGLRAAWTHGEDVYAEVALPEGTTQEAGRFDLHPALLDA ALHPLGLGTFDGFGDGRVLFSLADASLRATGATTLRVRLARRGPDTLTLEAADAIGEPVL TIASLLMRPLDPHHTSAPAAPATTDRPAPARTRAVARRTAARAQQPGSLLERLSNRPPAE RARVLLTTVRTQVADVLGYEGPTDIEPAHSFSTLGFTSLTSVELRDALSTALGVALPATL VFDHPTPHALARHLDADLFGGTTDDDGPTRRPASADDDPIVIVGMACRYPGGVRSPEDLW DLVVAGADGISPLPGDRNWSPETLYHPDPDHPGTVYTREGGFLHDASQFDPSFFGISPRE ALAMDPQQRLLLETSWEALERAGIDPATARGSRTGVFAGVTYQDYVTILAAADDNVEGYV GTGNSPSVLSGRIAYTLGLEGPAVSVDTACSSSLVALHLASQALRQGECTLALAGGVTVM STPGSLIEFSRQRALAPDGRCKPFSADADGASWAEGVGMIVLERLSDARRNHHPVLSVLR GSALNQDGASNGLTAPSGPSQQRVIRQALAGAGLTPAEVDAVEAHGTGTTLGDPIEAQAL IAVYGQDRPEARPLWLGSLKSNIGHSQAAAGVGGIIKMVMAIREGVLPRTLYADNPTPHV DWSAGDVRLLDQQRDWPETGRPRRAGVSSFGMSGTNAHVIVEQAPAPETATAPPATPDTA VFTGTLPVVPTLLSGRTEAALRSQAARLRTHLLARPDTPLTDLAYSQATTRSAFEHRAAV LATGRDTLDEALAALAAGAPVTGPGVVSGTAPTAADPVLVFPGQGAQWTGMARELLTESP LFAALVADCERALAPHIDWSLTAVLRGDEDAADIGRVDVVQPALWAVMVGLAGLWRSLGI TPAAVVGHSQGEIAAACVAGALSLDDGARIVALRSRAIVAIAGTGGMMSVPLSADETRAR MSPWADRLAVAAVNGPASVVVSGEAAALDELFTALTEDGVRARKVAVDYGSHSPQVEPIR ATVLDALAGIEPQDAAIPFRSSLTGQWQDTTTLDPEYWYTNLRETVRFEEAVRGLIAEGH RTFIEVSPHPVLAVGLRETLEDAGVEGAALGSLRRDKGGLGQFLTSVAEAHVNGVALDWT AVFTATGAHRVDVPTYPFQQQRYWPHVPERDTSASASSVTAATDTVESRFWETVDQGDPE AFADALDLPADAPLSAFLPALSTWRRTSRERSTTDSWRYGVGWSPLTDNAAGALSGTWLL VAPAGPDGIHDALVADAHRALTGGGARDTRLVTVPDGDTDRTHLAALLTAALTTEDATPA VAGVLSLLALDERPHPDHPALPHGLAGTVALLQALGDTDTDAPLWCATRGAVAVGPSETV TSPVQALVWGLGRVAALEHSERWGGLVDLPAALDGRAGTRLCAVLAAPGDEDQIAIRPSG SFGRRLVHAAAPLADTPAWHPRGTVLVTGGTGALGGHIARWLVGRGATHLVLAGRRGADA PGAAALRDELTALGADITLAACDVADRDALDALLRSIPADRPLDAVFHAAGSLDDTVVDS LTPERMDPVLRGKATAALHLHELTQDLDLSAFVLFSSSSGVLGGAGLGNYAPGNAYLDAL AQHRRSQGLPATAIAWGLWADGGMVGDAAGDRMRRYGVHPMDTKSACDALGRALDADDTT VVVTDLRWDTYALAFTGPRPSHLLDDLPAARRALDAARTQQAESPAADASSLQAHLAQLP AYDRAGAVLDVVRSYVANVLGYPSAEAVEPGRPFTDLGIDSLSAVELRNGMNRITGLRLP ATLVFDHPNCDALAGHLLTELAGTQQPDTPASEPAVPPRDDEPIAVVAMGCRFPGDVSTP EQLWSMLLDGQEGLVPFPEDRGWDLDALYDPEPGKPGSVYTRTGGFLNDASGFDPAFFNI SPREAVAMDPQQRLLLEMTWETFERAGIDPRTLKGSRTGVFAGTNGQDYTGMLAASREDF EGYMLTGNAASVVSGRLSYTFGLEGPAVTVDTACSASLVALHLAVRSLRSGECDLALAGG VTVMASPGLFVDFSRQRGLSQDGRCKAFADAADGTGFSEGGGMLLVERLSDARRNNHPVL AVVRGSAVNQDGASNGLSAPNGPAQRRVIRAALADAGVKAAEVDAVEAHGTGTTLGDPIE AQAVLATYGQDREAGQPLWLGSVKSNIGHTQAGAGVAGIIKMVLALNNGVLPATLHVDQP STHVDWTEGDVRLLTEAVDWPGTDRPRRAGVSSFGISGTNAHVILEAATGEEPAPAPAAT EPAPAGGAVPWIVTARSRTALRAQAERLLTHLTDRPETDPADVGLSLAAHRSVFEHRAVV LGEDHDTLVQGLRSLADDEPNPSTVTGSARGEGKLAFLFSGQGAQRLGMGRELYDSFPVF TEAFDAVCAHLDDGLREVVFGEDADLLNETGWTQPALFAIEVALFRLVESWGMSPDFLVG HSVGELAAAHVAGVFSLEDACRLVSARGRLMQQLPSGGAMFALEAAEDEVLPLLEGRETE VSVAAVNGPRSVVISGVEAVAEAIAQEITALGRRTSRLRVSHAFHSPLMEPMLAEFRAVA ESVTYTPARMAVVSNVTGQAAGAGELESADYWVRHVREAVRFADGITWLEGRGVRRFVEL GPDGTLTALAQTSASGGDEMLFVPVLRKDRPEREALLLGLAQAFAKGVDLEWAHVFDSTG ARTTTLPTYAFQRQRFWPGPPVLLGDVGSAGLDPAAHPLLGAAVELAGGDARLFTGRLSL RGQTWLADHALTSTALFPATGFLDLALHAAEHVGCDRVEELTILTPLTLPDSGALHVQLH VEAADANGARTLTVHTRTEDAGPETPWTLHASGLLTADATTTPETPYDFTAWPPQDADEV PLDGFYERFAERGHLYGPLFQGLKSVWTRGEEVFAEVALPEDADPSADAFDLHPALLDAA LHAVMFVPMKDAGRLPFSWNDVRLEAAGADALRVRMVQTGPESIGLALADTTGRPVATVG SLTLRELTGDLAGATIGAPRQEGLYELDWAPVSASAQTPGTDWTLVGGAEALPLTAELER AGSRVRAFPDLTALAASDLEIPETVLLVLPDTDTDTDTDTDAHTGGLAAAARATAHTTLR LVQQWLDEPRFAHARLAVVTRDAMRVGTRPADPARATAWGLVRSARSENPGRFVLADLDT APASAAALPAALASGHLELAVREGTVTTPKIIPLDVRRALTEPADTAAWRLCVEERGTLE SLKLTACPEVTGPLAPREVRISMRAAGVNFRDVLTALGMYPGDATAIGLEGAGVVTETGA DVTSLAVGDRVMGMFAGAFGPVAVADERMVAAVPRGWTFAQAATAPIVYLTAYYGLVDLG GLRPGQSVLVHAAAGGVGTAAVRLARHLGAEVFGTASPGKWDALRAAGLDDAHLASSRDL GFEKLFLETTEGRGVDVVLDSLAREFVDASLRLLPRGGHFLEMGKTDVRDPRQVAEDHPG VAYQAFDLVEAGPDRIGEMLRELVTLFEEGVLPPLPMTTFDVRRAPDAFRFLSQARHIGK VVLTLPTAPDPDGTVLLTGGTGGLGRITARHLVAHHGLRHLVLAGRQGPDAPGAAELREE LTALGADVAIVACDTADRAALADLLAALPPAHPLTAVIHTAGVLADGVISSMTPERIDRS MRPKADAVTNLHELTRDLDLARFVVFSSVAGTFGGAGQANYSAANAFLDALAHHRRDLGL PGTSLAWGTWLPDAGMTGELGQADRERHARTGMVPLGAELGMRLLDAGPATDRAVLLPMD LDHGSLREHADVLPPLLRAMVKAPARRRAETSATAAGGTQTLAERLAPLPAADREQLLLD AVAEQAAAVLGHSSAAEIEPEQSFKELGFDSLTAVELRNRLNAVTGLRLPATLVFDYPTP AVQVRHLLTQLDLPDPPGGAQALLGELDRLDAALNGTDVDDTEVRSRVTDRLRDLLARWS GAPVTVTGTGEPDAGDGELESVETADDLFDLIDRELGTT NT seq 13800 nt NT seq  +upstreamnt  +downstreamnt gtgtcggcccgcagcgccgccgccctgcgcgaacaggccgcacgcctgctggcccacgtc gaggagcaccccgcactcgacaccgccgacatcgcccacgcactggtgacgacccggccc ggcttcgaacaccgggccgtggtccgcggcaccgcacgcaccggactcctgcgcggcctc gccgccgtcgccgcgggcgaaccctccccggacgccgtcaccggcgacaccctgaccgag ggaaccaccgcgttcctgttcgccggccagggcacccagcggccgggcatgggccgcgag ctctacgacgccttccccgtctacgcggacgccttcgacgccgtgtgcggccacttcgaa ggccggctggaacagccgctgcgcgaggtcgtcctcggtgacgacgccgccctcctcgac cgcaccgagtacgcgcagcccgccctgttcgccgtcgaggtcgcgctgtaccgcctggtc gagtcctggggcgtacggccccaccacctcctgggccactccgtcggtgaactggccgcc gcccacgtcgcgggcgtcctcaccctgcccgacgcgtgccggctggtcgccgcccggggc cggctcatgcaggccctgccggagggcggcgccatgatcgcgctgcaggccaccgaggag gaggtcctgcccctgctggccgggcgggaggacgagatcggcctcgccgccctcaacggc ccccggtccgtggtggtcgccggcgacgagccggccgtactcgccgtggccgcgcacttc gcgggccagggacgcaagaccacccggctgcgcgtcagccacgccttccactcaccccgc atggaaccgatgctggccgacttccgggccgtcgccgaaagcatcggctacgccgagccg cgcatcccggtcgtctccgacctcaccggcaggcccgccgaggccggggaactcacctcg cccgagtactgggtgcgccacgtccggcaggccgtccgcttcgccgacgggatcgcctgg ctggaacaccacggcgtcgagcactgcctcgaactcggccccgacgccaccctcaccacc ctcgcccagggctgctgggagtcccacggtcacctcaccgtgcccgcgctgcgcgccgac cgccccgaaccggccgtcctcctcgccgccctgggcgccctgttcacccgcggtgtcccg gtcgactggcagtcctgcctggacgcggccgcccccggcggccggcccgtacccctgccc acctacgccttccagcaccgcacgttctggctcgacgtacccaccggatccggtgacccg gccgcggccggactcctcgacgcggaccacccgctgctgagcgccgtcgtcccgcccgcc gagggcgccaccgtcgtcctgaccggacgcctgtcggcccacgcgcagccctggctcgcc gcccaccgcgtcaacggctccgtcgtggtgccgagcaccgccttcctcgaactcgccctg cgcgccggtgcccacaccgactgcgggcacgtacgcgaactcgtcctcgaatccccgctc gtcctgcccgaacacggccgcgtccacctccagatccgggtcgccgaacccgacgcgctg ggctcccgcgtcttcggcgtgtacggccggcccgagaacctcaacaacccggacaacttg aacgcggccggcccctggacccggcacgccggcggcctgttgagcacccggcaccccgaa cgcacaaccggcgccccggagttcgacttcaccgcctggccgcccccgggcgccgaaccc ctcgacgtcgacggcgtctacgaacggctcgccgccgcgggactcgactacgggcccgtc ttccagggcctgcgggccgcctggacccacggcgaggacgtgtacgccgaagtcgccctc cccgaaggcaccacgcaggaggccggacgcttcgacctgcaccccgcgctcctggacgcc gccctgcacccgctcggcctgggcaccttcgacggattcggcgacggccgcgtcctgttc tccctcgccgacgcctcgctccgggccaccggcgccaccaccctgcgcgtccggctcgcc cgccgcggccccgacaccctgaccctggaagccgccgacgcgatcggcgaacccgtcctc accatcgcctccctgctgatgcggcccctcgacccgcaccacacgagcgcccccgccgcc cccgccaccaccgaccggcccgcccccgcccgcacccgggccgtcgcccgccgcaccgcg gcccgcgcccagcagcccggcagcctgctggagcggctgtcgaaccggcccccggccgaa cgcgcccgcgtcctgctcaccaccgtgcgcacccaggtcgccgacgtcctcggctacgag ggccccaccgacatcgagcccgcccactccttctccaccctcggattcacctcactcacc tccgtcgaactgcgcgacgcgctcagcaccgcgctcggcgtggccctcccggccaccctc gtcttcgaccaccccaccccccacgcactcgcccggcacctcgacgccgacctgttcggc ggcaccaccgacgacgacggccccacccgccgcccggcgtccgccgacgacgacccgatc gtcatcgtcggcatggcctgccgctaccccggcggcgtccgcagccccgaggacctgtgg gacctcgtcgtggccggcgccgacggcatctcgccactgcccggcgaccgcaactggagc ccggagaccctctaccaccccgaccccgaccacccgggcaccgtctacacccgcgagggc ggattcctccacgacgccagccagttcgacccctcgttcttcggcatcagcccccgcgag gccctcgccatggacccccagcagcgcctgctgctggagacgtcctgggaggcactggaa cgtgccggcatcgacccggccaccgcacgcggcagccgcaccggcgtcttcgccggcgtc acctaccaggactacgtcacgatcctggccgccgcagacgacaacgtcgagggctacgtc ggcaccggcaactcacccagcgtgctgtccggccgcatcgcctacaccctcggcctcgaa ggccccgcggtgtccgtcgacaccgcctgctcctccagcctcgtcgccctccacctcgcc tcccaggccctgcgccagggcgaatgcaccctcgcgctcgccggcggcgtgaccgtgatg tccacacccggctccctcatcgagttcagccgccagcgcgcactcgcccccgacggccgc tgcaagccgttctccgcggacgccgacggcgccagctgggccgagggcgtcggcatgatc gtcctcgaacggctctccgacgcccgccgcaaccaccaccccgtcctgtccgtgctccgc ggcagcgccctcaaccaggacggcgcctccaacggactgaccgcccccagcgggccctcg cagcagcgcgtcatccgccaggcgctcgccggcgccggcctcaccccggccgaggtcgac gcggtcgaggcacacggcaccggcaccaccctcggcgacccgatcgaggcccaggcgctc atcgcggtctacggccaggaccggcccgaggcccggcccctgtggctgggctccctgaag tccaacatcggccacagccaggccgccgccggcgtcggcggcatcatcaagatggtcatg gcgatccgcgagggcgtcctgccgcgcaccctgtacgccgacaaccccaccccgcacgtc gactggagcgccggcgacgtccgcctgctcgaccaacagcgggactggcccgagaccggg cgcccgcgccgcgccggtgtctcctcgttcggcatgagcggcaccaacgcccacgtcatc gtcgaacaggcacccgcccccgaaacggccaccgcaccgcccgcgaccccggacaccgcg gtcttcaccggcaccctgcccgtcgtaccgaccctgctgtccggccgcaccgaggccgcc ctgcgcagccaggccgcacgcctgcgcacccacctgctcgcccgccccgacaccccgctc accgacctcgcctactcccaggccaccacccgctcggccttcgaacaccgggcggccgtc ctcgccaccggccgcgacaccctcgacgaggcgctcgccgccctcgccgcgggcgccccc gtcaccggacccggcgtcgtctccggcaccgcgcccaccgccgccgaccccgtcctggtc ttccccggacagggcgcgcagtggaccggcatggcacgcgaactcctcaccgaatcaccc ctgttcgccgcactcgtcgccgactgcgaacgcgcgctcgccccccacatcgactggtcc ctgaccgcggtcctgcgcggcgacgaggacgcggccgacatcggccgggtcgacgtcgtc cagcccgccctgtgggccgtcatggtcggcctcgccggcctgtggcgctccctcggcatc acccccgcggccgtcgtcggccactcgcagggcgagatcgccgccgcctgcgtcgccggg gccctgtccctcgacgacggcgcccggatcgtcgccctgcgcagccgggccatcgtcgcc atcgccggcaccggcggcatgatgtccgtgccgctgagcgccgacgagacccgcgcccgc atgagtccgtgggccgaccgcctcgccgtcgccgccgtcaacggaccggcctcggtggtg gtgtccggcgaagccgccgcgctcgacgaactgttcaccgccctcaccgaggacggcgta cgcgcccgcaaggtcgccgtcgactacggctcccactcgccgcaggtcgaacccatccgc gcgaccgtgctcgacgccctcgccggcatcgaaccgcaggacgccgcgatccccttccgc tcgtccctcaccggccagtggcaggacaccaccaccctcgaccccgagtactggtacacc aacctgcgcgagaccgtccgcttcgaggaggccgtccgcggcctgatcgccgaaggccac cgcaccttcatcgaggtcagcccgcaccccgtgctcgccgtcggcctgcgcgagaccctg gaggacgccggcgtcgaaggcgccgcgctcggctccctgcgccgcgacaagggcggcctc ggccagttcctcacctccgtcgccgaggcccacgtgaacggcgtcgccctcgactggacg gccgtcttcaccgccaccggcgcccaccgcgtcgacgtacccacctaccccttccagcag cagcggtactggccccacgtgccggagcgggacacctccgcctccgcctcctccgtcacc gccgccacggacacggtggagtcccgcttctgggagaccgtcgaccagggagacccggaa gccttcgccgacgccctcgacctgcccgccgacgcaccgctgagcgccttcctgccggcc ctgtccacctggcgccgcaccagccgcgaacgctccaccacggactcctggcgctacggc gtcggatggtccccgctgaccgacaacgccgcgggcgccctgtccggcacctggctcctc gtcgccccagcaggcccggacggcatccacgacgccctcgtcgccgacgcccaccgcgcc ctgaccggcggcggcgcccgcgacacccgcctggtcaccgtccccgacggcgacaccgac cgcactcacctcgccgccctcctgacggccgccctcaccaccgaggacgccacccccgcc gtggcgggcgtcctgtccctgctcgccctcgacgaacgcccccaccccgaccacccggcg ctcccgcacggcctcgccggcaccgtcgccctcctccaggccctcggtgacaccgacacc gacgccccgctgtggtgcgccacccgcggcgccgtcgccgtcggcccctccgaaaccgtc accagccccgtccaggcactcgtctggggcctcggcagggtcgccgccctggaacactcc gaacgctggggcggcctcgtcgacctgcccgccgcactcgacggccgggccggcacccgc ctgtgcgccgtcctcgccgcccccggcgacgaggaccagattgcgatccggccctccggc tccttcggacgccgcctggtccacgccgccgcccccctcgccgacaccccggcctggcac ccgcgtggcaccgtcctggtcaccggcggcaccggcgccctcggcggccacatcgcccgc tggctcgtcggacgcggcgccacccacctggtcctggccggccggcgcggcgccgacgcc cccggcgcggccgcactgcgcgacgaactcaccgcactcggcgccgacatcaccctcgcc gcctgcgacgtcgccgaccgggacgccctggacgccctgctccgctcgatcccggccgac cgcccgctggacgccgtcttccacgccgccggctccctcgacgacaccgtcgtcgactcc ctgacacccgagcgcatggaccccgtcctgcgcggcaaggccaccgccgccctgcacctc cacgaactcacccaggacctggacctgtcggcgttcgtcctgttctcctcctcctccggc gtcctcggcggcgcgggcctgggcaactacgcccccggcaacgcctacctcgacgccctc gcccagcaccggcgctcccagggcctgcccgccaccgccatcgcctggggcctgtgggcc gacggcggcatggtcggcgacgccgccggcgaccgcatgcgccgctacggcgtccacccc atggacaccaagtccgcctgcgacgcactgggccgcgccctggacgccgacgacaccacc gtcgtcgtcaccgacctgcgctgggacacctacgcgctcgccttcaccggaccgcgcccc agccacctcctcgacgacctgcccgccgcccgccgcgccctggacgccgcccgcacccag caggccgagagccccgccgcggacgcctcctccctccaggcccacctggcccaactgccc gcctacgaccgggccggcgccgtcctcgacgtcgtccgctcctacgtcgccaatgtcctc ggctacccgtccgccgaggccgtcgaaccgggccgccccttcaccgacctgggcatcgac tccctcagcgccgtcgaactgcgcaacggcatgaaccgcatcaccggcctgcgcctgccg gccaccctcgtcttcgaccaccccaactgcgacgccctcgccggccacctcctgaccgag ctggccgggacgcaacagcccgacaccccggcctccgagcccgccgtacccccgcgggac gacgagccgatcgcggtcgtcgccatgggctgccgcttcccgggcgacgtcagcaccccc gaacagctgtggagcatgctgctcgacggccaggaggggctcgtccccttccccgaggac cgcggctgggacctcgacgcgctgtacgaccccgaacccggaaaacccggcagcgtctac acccgcaccggcggcttcctgaacgacgccagcggcttcgacccggcgttcttcaacatc tccccgcgcgaggccgtcgccatggacccgcagcagcggctgctgctggagatgacatgg gagacgttcgagcgggccggcatcgaccccaggactctgaagggcagccgcaccggcgtc ttcgccggcaccaacggccaggactacaccggcatgctggccgcctcccgggaggacttc gagggctacatgctgaccggcaacgccgccagcgtcgtctccggccggctctcctacacc ttcggcctggagggcccggcggtcaccgtcgacaccgcctgctcggcctccctcgtcgcc ctgcacctggccgtgcgctcactgcgctccggcgagtgcgacctcgccctcgccggcggc gtcaccgtgatggcctcacccggcctgttcgtggacttcagccggcagcgcggtctgtcg caggacggccgctgcaaggcgttcgcggacgccgccgacggcaccggcttctccgagggc ggcggcatgctcctggtggagcggctgtccgacgcccgccgcaacaaccaccccgtcctc gccgtcgtccgcggctccgccgtcaaccaggacggcgcctccaacggcctgagcgccccc aacggccccgcccagcgacgggtgatccgcgcggcgctcgccgacgcgggggtcaaggcc gcggaggtcgacgccgtcgaggcgcacggcaccggcaccaccctcggcgaccccatcgag gcccaggccgtcctcgccacctacggccaggaccgcgaggccggacagccgctgtggctc ggctcggtcaagtccaacatcggccacacccaggccggcgccggcgtcgccgggatcatc aagatggtcctggcactgaacaacggcgtcctgcccgccaccctccacgtcgaccagccc tcgacccacgtcgactggacggagggcgacgtccggctgctgaccgaggccgtcgactgg cccgggacggaccgtccccgccgcgccggtgtctcctccttcggcatcagcggcaccaac gcccacgtcatcctcgaagccgccaccggcgaggagcccgcgcccgcccccgccgccacc gaaccggcccccgccggcggcgcggtgccatggatcgtgaccgcccgcagccgcaccgcc ctgcgggcccaggccgagaggctcctcacccacctcaccgaccggccggagacggacccc gccgacgtgggcctgtccctggccgcgcaccgctcggtcttcgaacaccgcgcggtcgtc ctcggcgaggaccacgacaccctcgtccagggcctgcgctcactggccgacgacgagccg aacccctccaccgtgaccggctccgcccggggcgagggcaagctcgccttcctcttctcc ggccagggagcacaacgcctcggtatgggacgggagttgtacgactccttcccggtgttc accgaagccttcgacgcggtctgcgcgcacctggacgacggcctgcgcgaggtcgtgttc ggcgaggacgcggatctcctgaacgagacgggctggacacagcccgcactgttcgccatc gaggtcgcgttgttccggctggtggagtcgtgggggatgagccccgacttcctggtgggc cactcggtcggcgagctggccgccgcgcacgtggccggggtgttctcccttgaggacgcg tgccggctggtgtcggcgcgcggccgcctgatgcagcaacttccctccggcggggcgatg ttcgcgctggaagccgccgaggacgaagtgctcccgctgctggagggccgggagacggag gtgtcggtggccgccgtcaacggcccccgctcggtggtgatctccggcgtcgaagcggtg gcggaggccatcgcccaggagattacggccctgggccgccgcacctcccgcctgcgggtc tcccacgccttccactcgccgttgatggaaccgatgctggccgagttccgtgcggtcgcc gagagcgtgacgtacacgccggcccgtatggccgtcgtctcgaacgtgaccggacaggcc gccggcgcgggggagttggagtccgccgactactgggtccgccacgtgcgggaggccgta cggttcgccgacgggatcacctggctcgaaggacgcggcgtacgccggttcgtggagctc ggccccgacggcaccctcaccgccctcgcccagaccagtgcctccggcggcgacgagatg ctcttcgtccccgtcctgcgcaaggaccgccccgagcgcgaagcactgctcctcggcctg gcccaggcgttcgccaagggcgtcgacctcgagtgggcccacgtcttcgacagcaccggc gcacggaccacgaccctgccgacgtacgccttccagcggcagcggttctggcccggaccg cccgtcctgctcggcgacgtcggctcggcgggcctggaccccgccgcgcaccccctgctc ggtgccgcggtcgaactggccggaggcgacgcccgcctcttcaccggacgcctgtcgctg cgcggccagacctggctcgcggaccacgccctcaccagcacggccctgttcccggccacc ggcttcctcgacctggccctgcacgccgccgaacacgtcggctgcgaccgggtggaggaa ctgaccatcctcaccccgctcaccctccccgacagcggcgccctgcacgtacaactgcac gtggaggccgccgacgcgaacggcgcccgcaccctcaccgtgcacacgcggaccgaggac gccggccccgagacaccgtggacgctgcacgcctccggcctgctcaccgccgacgccacg accacgcccgaaaccccctacgacttcaccgcatggccgccgcaggacgccgacgaagta cccctcgacggcttctacgagcggttcgccgaacggggccacctgtacgggccgctcttc cagggcctgaagtcggtgtggacacgcggcgaggaggtgttcgccgaggtcgcgctgccc gaggacgccgacccgtccgccgacgcgttcgacctgcacccggcactgctcgacgccgcc ctgcacgccgtgatgttcgtgcccatgaaggacgcgggccggctgccgttctcctggaac gacgtccgcctggaggccgccggcgccgacgccctgcgggtgcgcatggtgcagacgggc ccggagtcgatcggcctggccctcgccgacaccacgggacgcccggtcgccaccgtcggc tccctcaccctgcgcgaactcaccggagacctcgcgggcgccaccatcggcgcaccgcgc caggaaggcctgtacgaactggactgggcgccggtgtccgcgagcgcccagacgcccggc acggactggaccctggtcggcggcgccgaagccctgccgctgacggcggaactggaacgg gccggctcacgggtgcgggccttccccgacctgaccgcgctcgccgcctcggacctcgag atccccgagaccgtcctgctggtcctgcccgacacggacacggacacggacaccgacacc gacgctcacaccggcggtctggccgccgccgcacgcgccaccgcgcacaccacactgcgg ctcgtgcagcagtggctcgacgaaccccgcttcgcccacgcccggctcgcggtcgtcacc cgcgacgccatgcgcgtcggaacccggcccgccgacccggcccgcgccaccgcctggggc ctggtccgctcggcccgctccgagaaccccggccgtttcgtcctcgccgacctcgacacc gcgcccgcctcggcggccgcgctgcccgccgccctcgcctccggccacctcgaactggcc gtcagggaaggcacggtgaccacaccgaagatcatccccctcgacgtgcggcgcgcgctc accgagcccgccgacacggccgcctggcggctctgcgtcgaggaacgcggaaccctggag agcctgaagctcaccgcgtgccccgaggtgacagggcccctcgcaccgcgcgaggtccgc atctcgatgcgcgccgcgggcgtcaacttccgcgacgtcctcaccgcgctcggcatgtat cccggcgacgccacggcgatcggcctggaaggcgccggcgtggtgacggagaccggtgcc gacgtcacctcactcgccgtcggcgaccgggtgatgggcatgttcgccggagccttcggc cccgtcgccgtcgccgacgaacgcatggtcgccgccgtcccgcgcggctggaccttcgcc caggccgccaccgcgcccatcgtctacctgaccgcgtactacggactcgtcgacctcggc gggctgcgcccaggccagtccgtgctcgtgcacgccgccgccgggggagtgggcacggcc gccgtacggctcgcccgccacctgggcgccgaggtgttcggcaccgcgagccccggcaag tgggacgcgctgcgcgccgcgggcctcgacgacgcccacctcgcctcctcccgcgacctc ggcttcgagaaactgttcctggagaccaccgagggccgcggcgtggacgtcgtactcgac tcgctggcacgcgagttcgtggacgcctcactgcggctgctgccgcgcggcggacacttc ctggaaatgggcaagaccgacgtccgtgacccgcggcaggtcgccgaggaccacccgggc gtcgcctaccaggccttcgacctcgtcgaggccggccccgaccgcatcggggagatgctg cgcgaactggtcaccctcttcgaggaaggggtgctgccgccactgccgatgaccacgttc gacgtacgccgggcccccgacgcgttccgcttcctcagccaggcacgccacatcggcaag gtcgtcctgaccctgccgaccgcccccgacccggacggcaccgtcctgctcaccggcggc accggcgggctgggccggatcacggcccgccacctggtcgcccaccacggcctgcgccat ctcgtcctggccggccggcagggacccgacgcgcccggcgccgccgaactgcgcgaggaa ctgaccgccctgggagccgatgtcgccatcgtcgcctgcgacaccgccgaccgcgccgcc ctcgccgacctcctcgccgcactgcccccggcccacccgctgaccgcggtcatccacacc gcgggcgtcctggccgacggtgtcatctcctcgatgacaccggaacgcatcgaccggtcg atgcggcccaaggccgacgccgtgaccaacctgcacgaactgacccgcgacctggacctc gcacggttcgtggtcttctcgtccgtggccggcacgttcggcggcgccggacaggccaac tactccgccgccaacgccttcctggacgccctggcccaccaccgccgcgacctgggcctg ccgggcacctccctcgcctggggcacctggctgcccgacgcgggcatgaccggcgaactc ggccaggccgaccgcgaacgccacgccaggaccggcatggtcccgctcggcgccgaactg ggcatgcgcctgctcgacgccggccccgccaccgaccgcgcggtgctcctgcccatggac ctcgaccacggctccctgcgcgaacacgccgacgtactgcccccgctgctgcgcgccatg gtcaaggcgcccgcccggcgccgggccgagacgtccgccaccgcggccggcggcacccag accctcgcggagcggctggccccgctgccggccgccgaccgggagcagctgctgctcgac gcggtcgccgagcaggccgcggccgtcctcggccactcctcggccgccgagatcgaaccc gagcagtccttcaaggaactcggcttcgactcgctgaccgcggtcgaactgcgcaaccgc ctcaacgccgtcaccggcctgcggctgccggcgaccctcgtcttcgactacccgaccccc gccgtccaggtccgccacctgctgacccagctcgacctgcccgacccgcccggcggcgcg caggccctgctgggcgaactggaccgcctggacgccgcgttgaacggcaccgacgtggac gacaccgaggtccgctcccgcgtcaccgaccggctgcgggacctgctggcccgctggtcg ggcgcgccggtgacggtcaccgggaccggggaaccggacgccggggacggcgaactcgaa tcggtcgagaccgccgacgatttgttcgacctcatcgacagggagctgggaacgacgtga

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