Streptococcus ruminantium: SR187_3025
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Entry
SR187_3025 CDS
T05916
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
srq
Streptococcus ruminantium
Pathway
srq00300
Lysine biosynthesis
srq00550
Peptidoglycan biosynthesis
srq01100
Metabolic pathways
srq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
srq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SR187_3025
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SR187_3025
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SR187_3025
Enzymes [BR:
srq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SR187_3025
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BBA92214
UniProt:
A0A2Z5TPC4
LinkDB
All DBs
Position
593253..594632
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AA seq
459 aa
AA seq
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MILEKYMKLHLHEIAQALSAKNDISTYPDRTLNKVEFDSRKIETGDLFVPLKGVRDGHDF
IPVAFDNGCAVTLSEKSLDVPHILVDDCLAALQKLAAYYLEKTGVEVIAVTGSNGKTTTK
DMIHDVLATTYKTYKTQGNYNNEIGLPYTILHMPDETEKLVLEMGQDHLGDIHLLSKLAK
PSLSVITLFGEAHLEFFGSREQIAQGKLQIADGMSAGGELIIPADPIAEAHLPINQKIIR
FGDGADLQLTSLIESKDSLNFTVNFINGEIFLPVTGKYNATNAMIASYVGKSLGVAEEAI
KSALANLNLTRNRTEWKKAANGADILSDVYNANPTAMRLILETFSTIPANEGGKKIAVLA
DMKELGQESVALHNQLILSLSPDVLDTVIFYGQDIEGLAQLASQMFPIGKVYFFRKNADQ
DQFEDLVSQVQTVLGKHDQILLKGSNSMNLAKLVEFLAG
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
ttgattttggagaaatacatgaaattacatctacacgaaattgctcaggcattgagcgca
aaaaacgatataagtacctaccctgataggactcttaacaaggttgaatttgatagccgc
aagattgaaacaggagacctttttgttcctcttaaaggtgtgcgtgacggtcatgacttt
attccagttgcttttgataatggctgcgcagttactctatctgagaaaagccttgatgtt
ccccatattctagttgatgattgcttggctgcgctacaaaaattagctgcctactatcta
gaaaaaacaggtgttgaggtcatagcagtcactggctcaaacggaaaaacaacgactaag
gacatgattcatgatgttctagcaacgacttacaaaacctataagacccagggcaactat
aacaatgaaatcggcctgccttataccatccttcatatgccagatgaaacagagaaacta
gttttggaaatggggcaggatcatcttggcgatattcatctgttatctaaacttgccaaa
cccagtctatcggttatcacgctttttggcgaggcgcatttagaattctttggatcgcgt
gagcagattgcgcaagggaaattacagattgcagatggcatgtctgctggaggcgaactg
attattccggctgatccaatcgcagaagcccatttacctatcaatcaaaaaatcatccgt
tttggagatggtgctgatctgcagctaacaagcctaatcgaatccaaagacagtttgaac
tttacggtcaactttatcaacggggagattttccttcccgtgacggggaaatacaatgca
acgaatgctatgatagctagttatgttgggaagagtttaggtgtggcagaggaagctatt
aaatccgctttggccaacctcaacctaactcgcaatcgtaccgagtggaaaaaggcagca
aacggtgcagatattctcagcgatgtttacaatgccaatccaacagcaatgcgcttgatt
ttggaaactttttcaaccattccagccaatgaaggtggtaagaaaattgcagttttggcg
gatatgaaggagttgggacaggaatctgttgccctccataaccaactgattttgagtctg
tcgccagatgttttagatacggttattttctacggtcaagatattgagggcttggctcag
ctagccagtcagatgtttccgattggtaaggtttattttttccgaaaaaatgcagatcag
gatcaatttgaggatctagtcagtcaagtacagacagttcttggtaagcatgatcagatt
ttgctcaaaggctccaattcgatgaatctggcgaaattggttgagttcttagcaggttag
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