Streptomyces rutgersensis: F0345_06140
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Entry
F0345_06140 CDS
T08623
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
srug
Streptomyces rutgersensis
Pathway
srug00300
Lysine biosynthesis
srug00550
Peptidoglycan biosynthesis
srug01100
Metabolic pathways
srug01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
srug00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
F0345_06140 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
F0345_06140 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
F0345_06140 (murF)
Enzymes [BR:
srug01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
F0345_06140 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
Motif
Other DBs
NCBI-ProteinID:
QNE80754
LinkDB
All DBs
Position
complement(1511372..1512796)
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AA seq
474 aa
AA seq
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MIALSLAEINSIVGGQPADIPDLDAQVTGPVVIDSRLAAPGSLFAAFAGERADGHDYAAT
AVETGAVAVLATRPVGVPALVVDDVERALGALARAVVERLGTAVVALTGSAGKTSTKDLV
AQLLQRIAPTVWTPGSLNNEIGLPLTALRADADTRHLVLEMGARGVGHIRYLTGLTPPRI
GVVLNVGSAHIGEFGGREQIALAKGELVESLPEDGVAVLNADDSYVRDMASRTKARVVTF
GEAPEADIRAENVRLTENGRPAFTLHTPSGCGDVTMRLYGEHHVSNALAAAAVASELGMP
VDEIAQALSEAESLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALVAMGGARRGEG
GRTWAVLGQMAELGDEALTEHDAVGRLAVRLNVSKLVAVGGTEAAWLRMGAYNEGSWGEE
SVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLEKVAAALLADGTGEGEVAAR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctcccttgccgagatcaacagcatcgtcggcgggcaacccgccgacata
ccggacctggacgcccaggtcaccggaccggtcgtgatcgactcccggctcgccgcccca
ggcagcctcttcgccgcgttcgccggtgaaagggccgacggccacgactacgcggccacc
gccgtggagaccggagccgtcgccgtcctcgcgacccggcccgtcggcgtgcccgccctc
gtcgtggacgacgtggagcgcgccctcggggcgctcgcgcgcgccgtcgtggagcgcctg
ggcacggccgtcgtcgccctcaccggctccgccggcaagacgtccaccaaggacctcgtc
gcgcaactgctccagcggatcgcgccgaccgtgtggacgcccggctccctcaacaacgag
atcgggctgccgctcaccgcgctgcgcgccgacgcggacacccgtcacctcgtcctggag
atgggggcccgcggcgtcgggcacatccggtacctcaccgggctgaccccgccgcggatc
ggtgtcgtcctcaacgtcggcagcgcccacatcggcgagttcggaggccgcgagcagatc
gccctggccaagggcgaactggtcgagtcgctccccgaggacggcgtcgcggtcctcaac
gccgacgactcctacgtccgtgacatggcctcacgtacgaaggcacgggtcgtcaccttc
ggcgaagcgcccgaagcggacatccgcgccgagaatgtccgtctcacggagaacggccgc
cccgccttcacgctgcacacaccctccgggtgcggcgacgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgccgccgccgtcgcatcggaactgggcatgccc
gtggacgagatcgcccaagcgctctccgaggcggagtccctgtcccgctggcggatggag
gtcaccgagcgcccggacggtgtgacgatcgtcaacgacgcctacaacgcgaaccccgaa
tccatgcgggccgccctgcgcgcgctcgtggcgatgggcggcgcccgccgcggcgagggg
ggccgcacctgggcggtgctcggacagatggccgagctgggggacgaggcgctcaccgaa
cacgatgccgtcgggcggctcgccgtccggctgaacgtgagcaagctcgtggcagtcggc
ggcacggaagcggcctggctgcggatgggcgcatacaacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggcggtcgacctgttgcgcagcgagctgcgcccg
ggagacgtcgtactcgtgaaggcttcccggtccgtgggactggagaaggtcgccgccgct
ctgctggcggacggtacgggcgagggtgaggtcgccgcccgatga
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