Streptomyces rutgersensis: F0345_21725
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Entry
F0345_21725 CDS
T08623
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
srug
Streptomyces rutgersensis
Pathway
srug00290
Valine, leucine and isoleucine biosynthesis
srug00660
C5-Branched dibasic acid metabolism
srug01100
Metabolic pathways
srug01110
Biosynthesis of secondary metabolites
srug01210
2-Oxocarboxylic acid metabolism
srug01230
Biosynthesis of amino acids
Module
srug_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
srug00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
F0345_21725 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
F0345_21725 (leuC)
Enzymes [BR:
srug01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
F0345_21725 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
F0345_21725 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QNE83405
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Position
5148837..5150255
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AA seq
472 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRAVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNCADFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMTRPRTMAITVEGELPEGVSA
KDLILAVIARIGTGGGQGYVLEYRGPAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGRAHAPRGQEWDEAVAYWKTLRSDDDAAFDAEVVIDAATLAPFVTWGTNPGQGAPL
SAHVPDPASFEDPSARYAAEKALEYMGLQAGQALRDIKVDTVFVGSCTNGRIEDLRAAAG
IVKGRKVADGVRMLVVPGSARVGLQAVEEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVTGTLASPADLTDVPAGV
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagccggaccttctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggtctgcgcaaggccgggcgcgccgtgcgccgcctcgacctcaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagcccatcgccgatccggtctcccgg
gtccagctggagacgctgcgcaagaactgcgccgacttcggggtgcggctgcactcgctc
ggcgacgtcgagcagggcgtcgtgcacgtggtcgggccgcagctcggcctgacccagccg
ggcaccacggtcgtctgcggtgactcgcacacctccacccacggggccttcggcgcgctg
gcgttcggcatcggcaccagccaggtcgagcacgtactggccacccagacgctgccgatg
acccgtccgcgcaccatggcgatcaccgtcgagggcgaactgcccgagggcgtcagcgcc
aaggacctgatcctcgccgtcatcgcccgcatcggcaccggcggcggccaggggtacgtc
ctggagtaccggggcccggccatcgagaaactctcgatggaggcgcggatgaccatctgc
aacatgtccatcgaggcaggcgcccgggccggcatgatcgccccggacgagaccaccttc
gcctacctggaaggccgcgcccacgcgccgcgggggcaggagtgggacgaggccgtcgcc
tactggaagacgctgcgctccgacgacgacgccgcattcgacgccgaggtcgtcatcgac
gccgccaccctggcgccgttcgtcacctggggcaccaatcccggacagggggcgcccctg
agcgcccacgtgccggaccccgcctccttcgaggacccgtccgcgcggtacgccgccgag
aaggcgttggagtacatggggctccaggccgggcaggcgctgcgggacatcaaggtcgac
accgtcttcgtcggctcctgcaccaacggccggatcgaggacctgcgggccgccgccggc
atcgtcaagggccgcaaggtggccgacggcgtccgcatgctcgtggtccccggctccgcc
cgggtcggcctccaggccgtcgaggagggcctggacgtcgtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctcgccccc
ggtgagcgctccgcctccacctccaaccgcaacttcgagggacgccagggcaagggcggc
cgtacccacctggtctcgccgcaggtggccgccgcgaccgccgtcaccggcacgctcgcc
tcgcccgccgacctcaccgacgtacccgcgggagtctga
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