Streptomyces reticuli: TUE45_03218
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Entry
TUE45_03218 CDS
T04246
Symbol
fgs
Name
(GenBank) Folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
srw
Streptomyces reticuli
Pathway
srw00790
Folate biosynthesis
srw01100
Metabolic pathways
srw01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
srw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
TUE45_03218 (fgs)
Enzymes [BR:
srw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
TUE45_03218 (fgs)
6.3.2.17 tetrahydrofolate synthase
TUE45_03218 (fgs)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
CUW28482
LinkDB
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Position
I:complement(3726114..3727628)
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AA seq
504 aa
AA seq
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MSDHPGTSDTPDPLDSFDEIIEAETTRDPDLAVIEAGSRTLRTQGGPPQADIPARPEDPE
VDKALREVEAELATRWGETKLEPSVSRISALMDVLGEPQRSYPSIHITGTNGKTSTARMI
EALLGAFELRTGRYTSPHVQSITERISLDGAPITAERFIETYQDIKPYVEMVDGQQEYRL
SFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLGETP
AEIAAEKSGIIKQDATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVARQVAVGGQ
LLTLRGLGGEYAEVYLPLHGAHQAHNAAVALAAVEAFFGVGAQRAEPLDIDTVRKAFAAV
SSPGRLEVVRRSPTVVLDAAHNPAGAEATAEAVREAFDFSRLIGVVGASGDKNVRGLLEA
FEPIFAEVVVTQNSSHRAMDADELAAIAVEVFGDERVQVEPRLPDALEAAITLAEEEGEF
AGGGVLVTGSVITVGEARLLLGKG
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgaccaccccggcaccagcgacacccccgaccccctcgacagcttcgacgagatc
atcgaagccgagaccacccgcgaccccgacctcgcggtgatcgaggccggcagccgcacc
ctgcgcacccagggcggcccgccccaggccgacatccccgcgcgccccgaggacccggag
gtcgacaaggccctgcgcgaggtcgaggccgagctggcgacccgctggggcgagaccaag
ctggagccctcggtcagcaggatctccgcgctgatggacgtcctcggcgagccccagcgc
tcgtacccctcgatccacatcacgggcaccaacggcaagacctccacggcccgcatgatc
gaggccctgctcggcgccttcgagctgcgcaccggccgctacaccagcccgcacgtgcag
tcgatcaccgagcggatcagcctggacggcgccccgatcaccgccgagcggttcatcgag
acgtaccaggacatcaagccgtacgtggagatggtggacggacagcaggagtaccggctg
tccttcttcgaggtgctcaccggcatggcgtacgcggccttcgcggacgcccccgtggac
gtcgccgtcgtcgaggtcggcatgggcggctcctgggacgccacgaacgtgatcgacggc
gatgtcgcggtggtgaccccgatcgatctcgaccacaccgaccggctcggcgagacgccc
gcggagatcgccgccgagaagagcggcatcatcaagcaggacgcgaccgtcatcctggcc
cagcagccggtggacgcggcgcaggtgctgctgaagaaggccgtcgaggtggacgcgacc
gtggcccgcgagggcctggagttcggcgtcgtcgcccggcaggtcgccgtcggcgggcag
ctgctcacgctgcgcggcctcggcggcgagtacgccgaggtgtacctcccgctgcacggc
gcccaccaggcgcacaacgcggccgtcgcgctcgccgccgtggaggcgttcttcggcgtc
ggcgcgcagcgcgcggagccgctggacatcgacacggtccgcaaggccttcgcggccgtc
tcctcgccgggccgcctggaggtcgtacgccgctccccgacggtcgtgctggacgcggcg
cacaacccggccggtgccgaggccaccgccgaggcggtgcgcgaggcgttcgacttcagc
cggctgatcggggtcgtgggcgcgagcggtgacaagaacgtgcgggggctgctggaggcc
ttcgagccgatcttcgccgaggtcgtcgtcacccagaactccagccaccgtgccatggac
gcggacgagctggccgcgatcgccgtcgaggtgttcggcgacgagcgcgtgcaggtcgag
ccgcggctgccggacgccctggaggccgcgatcacgctggccgaggaggagggcgagttc
gccggcggcggtgtgctggtgaccggttccgtcatcacggtcggcgaggcccggctgctg
ctcggaaagggctga
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