Streptococcus sanguinis: SSA_0198
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Entry
SSA_0198 CDS
T00473
Name
(GenBank) Dihydrofolate synthetase, putative
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ssa
Streptococcus sanguinis
Pathway
ssa00790
Folate biosynthesis
ssa01100
Metabolic pathways
ssa01240
Biosynthesis of cofactors
Module
ssa_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ssa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SSA_0198
Enzymes [BR:
ssa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SSA_0198
6.3.2.17 tetrahydrofolate synthase
SSA_0198
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
DUF3670
Motif
Other DBs
NCBI-ProteinID:
ABN43658
UniProt:
A3CKF3
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Position
197041..198435
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AA seq
464 aa
AA seq
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MKKQELPDLSWLEAYRTASPNFGLERMERLLELRGDPHLQLPVIHIAGTNGKGSTIAHLR
QLLEVRGLRVGTFTSPYLVSYNEQIAINGNAISDQDLQRLLSLYQDLLAQHATDSGLQGV
TEFEIVTALAYDYFVQQQVDVAIIEVGMGGLLDSTNVCQPLLTAITTVGLDHVALLGDSL
EAIAQQKAGIIKHGVPIVTGRLEPEALAVVEQKAAEKDSPLFSWSQAYQVEPQESEEGEC
FSFSNAYRAKDSYQTALMGLHQADNAGLALHLCDLYCQLQSLSLLTKAEVERALLTAEWP
GRLERISDQPLILLDGAHNPHALRSLAATLDQHYPTYKKHILFACIQTKALDDMVELLQK
IPKAAISLTAFADPRSFSKESMQSLAEQQGLSYKEWPDYVADYLAVEHEPDELLLITGSL
YFLAQVRKSILENCKLDFAERPSQSSQLSKNKNEHRSIYGHEEN
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaaacaagaattacctgatttaagttggctggaagcctatcggacagccagtccc
aattttggcttggagcggatggagcgtttactggagttgcggggggatccgcatttgcag
ctgccagtcattcatattgcagggactaatggcaagggttcaaccattgcccatctgcgc
caactcttggaagtgcgaggcttgcgggttggcactttcacctctccctacctagtcagc
tacaatgagcagattgccattaatggcaatgcgatttccgaccaagatcttcagcgattg
ctgagcctttatcaggacctcttagcccagcatgcgacagactctggcttgcagggggtg
actgagtttgagattgtaactgctctagcttatgattattttgtccagcagcaggtggat
gtggctattatcgaggtcggcatgggtgggcttttggatagtaccaatgtctgccagccc
ttactgactgcaatcacaacagtcggtctggatcatgtggccttgctaggtgacagtcta
gaggctattgcccagcagaaagctggcattatcaagcatggagttcccattgtgaccggt
aggttggagccagaggctctggcagtagtcgagcaaaaggctgctgaaaaagattctccg
ctcttttcttggtctcaagcttatcaagtggaacctcaagagtcagaggagggggagtgc
ttttccttttcgaatgcctatcgggccaaagactcgtatcaaacagctctgatgggactg
catcaggcggacaatgctgggctagctctgcacttgtgtgacctatactgccagctgcag
tcgctgtccttattgacaaaagcagaggttgagagggccttgcttactgctgagtggcct
ggtcgtttggaaaggatatcggatcagccgcttattcttctggatggagcccataatccc
catgccctgcggtcgttagcagcgacactggaccagcattatccgacttataagaagcac
attttatttgcttgtatccaaaccaaggccttggatgatatggtggagctgctgcaaaag
attcccaaagcagctataagcttgacagcctttgctgatccgcggagtttttctaaagag
agcatgcaatccttggctgagcagcaaggcctgtcttacaaagaatggccggattatgta
gcagattatttagcagtagagcatgagccggatgagcttttgctgattacgggttctctt
tattttctggctcaggttagaaaatcaatccttgagaattgcaagttagactttgctgag
cgtccttctcagtcaagtcaattatcaaaaaataaaaatgaacataggagcatatatgga
cacgaagaaaattga
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