Streptococcus sanguinis: SSA_0474
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Entry
SSA_0474 CDS
T00473
Name
(GenBank) Uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase, putative
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
ssa
Streptococcus sanguinis
Pathway
ssa00860
Porphyrin metabolism
ssa01100
Metabolic pathways
ssa01110
Biosynthesis of secondary metabolites
ssa01120
Microbial metabolism in diverse environments
ssa01240
Biosynthesis of cofactors
Module
ssa_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
ssa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SSA_0474
Enzymes [BR:
ssa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SSA_0474
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SSA_0474
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Gene cluster
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Motif
Pfam:
TP_methylase
HEM4
KRTDAP
Motif
Other DBs
NCBI-ProteinID:
ABN43922
UniProt:
A3CL67
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Position
476410..477849
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AA seq
479 aa
AA seq
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MSGLVTLLGAGPGDAELLSLKGKRRLQEADVLVFDRLVNQELFQHLKSDCEKIDVGKKPG
QPCIRQEEIEKILIEKARQGKRVVRLKSGDPYIFGRGGEEGVKLVEAGVDFEVVPGITSA
VAGLTYAGIPMTYRDVATSFHVFTAHLKDETEMLNWEAISKLKGTLVFLMGMKNLPTIVQ
ELTARGYGKDKPAAIVEWGTHPQQRSVDGTLGNIVELAEAEDFKAPSVIVVGDVVAYRQQ
LNFHENLPLFGRKILIQQSETGRLPRLLKDAGAALTTFPARDLVEELELQLPDLEQVDGL
LFADMQSWPLFLKALRKAGKDLRSLPHIRFAAIGHHTAKSIEASGIVLDRMTPQQSDTDF
ATALEKEGGNWYILTAEHKKASLAELYSMPIIASHRLAFGSQINSTNWLEIEVVCLPNSA
AAMNFVAASQEAGFDWKDVPIVVMGASTRAVLAEAGFSKIVETDEATIASIVDKCREIL
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgtccggtttagtaacattactgggagcaggtccaggcgatgcggagttgttgagtctc
aaaggcaagagacggcttcaagaagcagatgtcttggtctttgaccgcttggtcaatcaa
gagctctttcagcatctaaagtctgactgcgaaaagatagatgtgggtaaaaagccaggc
cagccctgcatccgacaggaagaaattgaaaaaattctcatcgaaaaagcccgtcagggc
aagcgggtagtccgcctcaagagcggtgatccctatatctttggccgaggcggagaagaa
ggagtcaagctggtggaagctggtgtggactttgaagtggtgccaggcatcacttctgct
gtggctggtctgacctatgcaggaattcctatgacttatcgggatgtagcgactagcttc
catgtctttacagcccatctcaaggatgagacagaaatgctcaactgggaagcaatttct
aagctcaaaggaaccttggtcttcctcatgggcatgaaaaatctgcctaccatcgtccaa
gagctgacggctagaggctatggcaaggacaagccagccgccatcgttgaatggggaacc
catcctcagcagcgctcagtggacggaaccttggggaacatagtcgaactagcagaagct
gaagactttaaggcaccgagtgtcatcgtggtaggtgatgtcgtggcctatagacagcag
ctgaatttccatgagaatctgccacttttcggtcgtaaaatccttatccaacagtcagag
actggcagacttcctcgcttgcttaaggatgctggagctgcgctgaccactttcccagct
cgagacttggttgaagagttagaattgcagctgccggacttggagcaggtagacggtctc
ctctttgcagatatgcagagctggccgctcttcttgaaagccctccgcaaggcaggcaaa
gacttgcgcagtctgccgcacatccgctttgcagcgattggtcatcatacggctaaatct
atcgaagcgagcggcattgtgctggatcggatgacgccacagcagtcggatacggatttt
gcaactgctcttgaaaaagaaggcggtaactggtatattctgacagctgagcataaaaaa
gccagtctggcagaactctattcgatgccgattattgctagccacaggctggcctttggc
agtcagattaacagtaccaattggttagagattgaagtagtctgtctcccgaactctgct
gcagccatgaactttgtagcagctagtcaagaagctggatttgactggaaggatgttcca
atcgttgtcatgggtgctagcacgcgggctgttttagcagaagcaggctttagcaagatt
gttgagacggatgaagctactattgcttccatcgttgacaaatgtcgggaaattctctga
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