Spiribacter salinus: SPISAL_02195
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Entry
SPISAL_02195 CDS
T02685
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ssal
Spiribacter salinus
Pathway
ssal00230
Purine metabolism
ssal01100
Metabolic pathways
ssal01110
Biosynthesis of secondary metabolites
Module
ssal_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ssal00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SPISAL_02195
Enzymes [BR:
ssal01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SPISAL_02195
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
DUF4202
Motif
Other DBs
NCBI-ProteinID:
AGM40536
UniProt:
R4VDY9
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Position
444344..448246
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AA seq
1300 aa
AA seq
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MMTLIAHAPREPVGDPRLIAQVRDAMPAVGALHARVVFFVDTQRTLTVVEVSRLQALLEA
EPLEAASGQDPTVLEPSIYVVPRLGTISPWASKATDIAHQCGLDGVRYIERGLRYTLADH
HGQPLDPRGSSDLTQALHDRMTESVLERLEDAEALFASHASRPLGQVELLSGGREALKAA
DQALGLALSGDEIDYLLENYTALERNPTDVELMMFAQANSEHCRHKIFNADWVIDGEAMP
HTLFAMIRHTHAERPEGVLSAYSDNAAVIAGGEIDRFTPRFDGGYGHRREPGHLVMKVET
HNHPTAISPFAGAATGVGGEIRDEAATGRGARTRAGLSGFSVSNLRIPGAEQPWEVDHGR
PDRIASALEIMLDGPIGAARYGNEFGRPQLAGYFRTYEQAVPGTDGKDVRGYHKPVMIAG
GMGTIRPDQVHKGMAPPGSPVVVLGGPAMLIGLGGGAASSVASGQSDEALDFASVQRSNP
EMERRCQEVIDACWGLGEESPIIAIHDVGAGGLSNALPELLDDADRGGRMELRTIPCAEA
GLSPLEIWCNEAQERYVLALDVDRLAVFQQICEREQAPFAVVGETTEARDLIVGDAEFGN
HPVHIPMDLLLGKPPKMRREVTRQTPPGQSLALDGVSLSEAIHRVLRLPTVASKEFLITI
ADRTVTGLTARDQMVGRWQVPVADYAMTVGDYRGYRGEAMAMGERSPVALLDAPASGRMA
IGEALTNLMGAPVGALAQVNLSANWMAACGHPGEDARLYDTVEAVGRALCPALGIAIPVG
KDSLSMKTVWDEGGEQRAVTSPLTLVVSAFAPANDVRRGVTPALAADPQSTLYLLDLGGG
RRLGGSALAQVYGQLGDVAPDLDDPDVFVRGFDTVQSLLAEGWVQALHDVSDGGVLVTLA
EMAFAGRAGVAVDLSLLAEAPLAAAFAEELGVVIQVSAENHERVEAAFEAAGLAERFTRL
GRPTAARHLVVRHHGAVVLDESLVDLEAAWHETSYQLQSLRDDPTCAQEAHEQVWDEADP
GLRAALSFNPAEDVAAPHIASTVRPRVAVLREQGVNSHVEMAAAFERAGFEPRDIHTTDL
LAQPHLLDDCQALVACGGFSYGDVLGAGRGWARKILFNPRLRAAFEGFFDRPDTLALGVC
NGCQMLSALREIIPGTTLWPDFLANRSRQYEARLSMVEVLPSRSVLLEGMEGSRMPIVVA
HGEGRAAFADDGGPRKALSAGLVGLRYIDGQDAPAATYPANPNGSPMGVTGLCNADGRVT
ITMPHPERVFRTLQHSWHPDEWGEDGPWMRLFRNARCALG
NT seq
3903 nt
NT seq
+upstream
nt +downstream
nt
atgatgacgttgatcgcacacgctccccgtgaaccggtgggcgacccgcgtctgattgcg
caggttcgcgatgcgatgccggccgtgggcgcgctgcatgcccgcgtggtgttttttgtg
gatacgcaacggacattgacggtggtggaggtcagccggctgcaggcattgcttgaagcg
gagccgctggaggccgctagcggccaggatcccacggtgcttgagccatcgatctatgtc
gtgccgaggctgggtacgatctcaccgtgggctagcaaagcaacggatatcgcgcatcaa
tgcggcctggatggcgtacgctacatcgagcgcgggttgcgctacacgctggctgatcac
catgggcagccccttgatccgcgcggctcatccgacctgacccaggctttgcacgaccgc
atgacggaatccgtgttagagcgtcttgaagacgctgaagcgctgtttgcgagccatgca
tcgcgccccttgggccaggtcgagttgctgagcggtgggcgtgaagcgttaaaagccgcg
gatcaggccctgggcctcgccctctcgggcgatgagatcgactacctgctcgagaattac
acggcgctggagcgcaatcccactgacgtggaactgatgatgtttgcgcaggcgaactcg
gagcactgccggcacaagattttcaacgctgactgggtgatcgatggcgaggccatgccg
cacaccctctttgccatgatccgtcatacccacgctgaaaggcccgagggtgtgctctca
gcctatagcgataacgcggccgtgattgccgggggtgagatcgatcggttcacaccgcgg
tttgatgggggttacggccatcgtcgtgagccagggcatctggtcatgaaagtggagacg
cacaaccaccccacggcgatctcgcccttcgcgggcgcggcgaccggtgtgggcggcgag
atccgtgatgaggcggccactgggcgtggggcgcgcacccgcgccgggctttccggattt
tccgtctccaatctgcgtattcccggtgctgagcagccctgggaggtcgatcacggccgc
ccggatcggatcgcctcggcgcttgagatcatgctggatgggcccatcggtgccgcacgc
tatggcaacgaattcggccgccctcaattagccgggtatttccggacctatgagcaggcc
gtgccgggtaccgatggcaaggacgtgcgtggctatcacaagccggtgatgattgcgggg
ggcatgggcacgatccgcccggatcaggtgcataagggcatggcgcctccgggctcgccc
gtggtggtcctgggtggcccggcgatgctaatcggcctgggcggcggggcggcctcgtcc
gtggcgagcgggcagagtgacgaggccctggattttgcctcagtccagcggagcaacccg
gaaatggagcgtcgctgtcaggaggtgatcgacgcgtgctgggggctcggcgaggagagt
cccatcatcgcgattcacgatgtcggcgcgggtgggctatcgaatgcgttgcccgagctg
ctggacgacgccgaccgcggcggccgaatggagctgcgcacgatcccttgtgccgaggca
ggcctctcgccgctcgagatctggtgcaacgaggcccaggagcgctacgtgctggccctg
gatgtcgatcgtctggcggtcttccagcaaatctgcgagcgtgagcaggcgccgtttgcg
gtggttggcgagaccacggaggcgcgcgaccttatcgtcggggatgccgagttcggtaat
cacccggtccatatcccgatggatctgctccttggcaagccgccgaagatgcggcgtgag
gtgacccggcaaacaccacctgggcaatcgctggcgcttgacggtgtcagtctgtccgag
gcgattcaccgggtgctgcgcttgcccacggtggccagcaaggaatttctgattaccatt
gcggatcgcacggtcaccgggctgacggcgcgggatcagatggtgggccgctggcaggtg
cccgtggccgattacgccatgacggtgggcgattatcggggctaccgcggtgaggccatg
gccatgggtgaacgcagcccggtggcgctgctcgacgcgccagcctcgggccggatggcc
attggcgaggccctgaccaacctcatgggggcgccggtcggcgcactggcccaggtcaat
ttgtcggcgaactggatggccgcttgtggccatcctggggaagatgcccggctctacgac
accgtggaggcggtgggccgcgcgctctgtccggcactcgggattgccattcccgtgggc
aaggactcgctatcaatgaaaacggtctgggacgagggcggcgaacagcgggctgttacc
tcgccgctcaccctggtggtttccgcgttcgccccggcgaatgatgtccggcggggcgtg
acgccagccctcgcagccgatccgcaaagcaccctgtacttgctcgatctggggggcgga
cgtcgtctgggcggatccgccctggcgcaggtctatggtcagttgggtgatgttgccccg
gatctggatgatccggacgtctttgtccggggttttgatacggtgcaatcgctgctggcc
gagggttgggttcaggcgctgcatgatgtctcggacggtggcgtgctggtgacgctcgcg
gaaatggcttttgccgggcgcgccggcgtggcggtggacctctctttgctggctgaggcg
ccgctggcggcggcctttgccgaggagctgggtgtggtcatccaggtgagtgcagagaat
cacgagcgcgtcgaggccgccttcgaggccgcagggcttgcggagcggttcacgcgtctg
ggccggcccacggcggcccggcatctggtcgtgcgtcaccacggcgcggtcgtgcttgat
gagtcgctggtcgatctcgaggctgcctggcacgaaaccagttatcagcttcagtctctg
cgcgatgatccgacctgtgcccaagaggcgcatgagcaggtgtgggacgaggcggacccg
gggcttcgggccgcgttgagttttaacccggctgaggacgtcgctgcgccccatatcgcc
agtacggtacgaccacgggttgccgtgcttcgcgagcagggcgtcaatagccacgtagag
atggcggcggcgtttgagcgggcaggctttgagccgcgggatatccacaccaccgatcta
ttggcgcaacctcatctgcttgatgactgccaggcgctggtggcctgcggtgggttctcc
tacggggacgtgttgggcgctggccggggctgggcgcgcaagattttgtttaacccgcgg
ttgcgggcggcctttgagggctttttcgatcgcccggatacgctggcgcttggcgtgtgt
aacggctgccagatgctttcggcactccgcgagatcatcccgggcacgaccctgtggccg
gattttctcgccaatcgctcgcgtcagtacgaagcgcgccttagcatggtggaagtgctg
ccctcacgctccgtgcttctcgaggggatggaagggtctcgaatgcccatcgtcgtcgcg
cacggcgagggccgggccgcgtttgctgatgacggtggcccgcgcaaggcgttgtcagcc
gggttggttggactgcgttatattgatgggcaagacgccccggccgcgacctatccggcc
aacccgaatggctccccgatgggcgtcacgggtctgtgcaatgccgatggtcgagtcacg
attacgatgccgcatccagagcgcgtgttccgcacgctgcagcatagctggcaccccgat
gagtggggggaggatgggccgtggatgcggctgttccgaaatgcccggtgcgccctcggt
tag
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