Sus scrofa (pig): 100312973
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Entry
100312973 CDS
T01009
Symbol
HSD17B2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc00140
Steroid hormone biosynthesis
ssc01100
Metabolic pathways
ssc04913
Ovarian steroidogenesis
Module
ssc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100312973 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100312973 (HSD17B2)
Enzymes [BR:
ssc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
100312973 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
100312973 (HSD17B2)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Epimerase
Motif
Other DBs
NCBI-GeneID:
100312973
NCBI-ProteinID:
NP_001161121
Ensembl:
ENSSSCG00000002686
UniProt:
D0G6Y1
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Position
6:complement(6296429..6360434)
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AA seq
388 aa
AA seq
DB search
MGTFFSETGWLCLTVTAVLGAVILCKLKKNHRQEGRKMVCLAGLWGGACLLSLSLFWGLI
LFSLSCFLMYAYFSGQEFLPVDQKAVLITGGDSGIGHALSKYLDKLGFIVFAGVLDEKGS
GAEELRRTCSKHLSVLQLDITNSQQIRDAHSKVMEKVQNRGLWAVVNNAGILGFPIDGEL
IPMTQYKRCMAVNFFGAVEVTKAFLPLLRKSKGRLVNISSMAGGVPMEKMAAYSSTKAAL
TMFSAVMRKELSKWGVKVSVIQPGSFQTNIAGTSDLWDKLEKNILDDLTPNLQEDYGQDY
ILKQRSFLKFMSNSSEPDISPVLLDVQHAISAKSPYAFYTPGKMSFLWLCFASFSPTVLF
DYFSKSSHSFTRGMPRALSKANWKNEAM
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
atgggcacgttcttctctgagacagggtggctctgcctgactgtcacggcagtgctggga
gcagtaattctttgcaaactcaagaagaaccacaggcaggagggcagaaagatggtctgc
ctggctggcctctggggaggggcttgcctgctcagcctctctctcttctggggcttgatc
ctcttctccctgtcatgttttctcatgtatgcttacttttctggccaagagtttttacct
gtggatcaaaaggcggtgctgatcacaggtggcgattctgggattggccatgctttgtcc
aagtatctggataagctgggattcatagtatttgctggagttctggatgaaaagggatca
ggagcagaggaactacgaagaacctgctccaagcacctgtctgtgctccagctggacatc
accaactcgcagcagataagagatgctcacagcaaagtgatggaaaaggtgcagaacaga
ggactgtgggctgtggtcaacaacgcagggatccttggcttcccaatcgatggggagctc
attcctatgacccaatacaaacgatgcatggccgtgaacttcttcggggccgtggaagtc
accaaggcatttttgcctcttcttaggaaatccaagggcaggctggtgaacatcagcagc
atggcaggaggggttccaatggagaagatggcggcctacagctcaaccaaggcagctctg
accatgttttcggcagtcatgagaaaagagctatccaaatggggagttaaagtctctgtc
atccagcctggaagcttccaaacaaacatcgcaggcacgagtgacctgtgggacaagctg
gagaaaaacatcctggacgacctcacccctaacctgcaggaggactacggccaggactat
atccttaagcaacgcagttttctcaagttcatgagcaacagctctgaaccggacatctcc
ccagtgctcctggacgtccagcatgccatctctgctaagagcccctatgcattttacacg
cccggaaaaatgtcttttttgtggctctgctttgcttcatttagccctactgtcctattt
gattactttagcaaaagctcacatagttttacaaggggcatgcccagagcattgagcaag
gctaactggaagaatgaggccatgtag
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