Sus scrofa (pig): 100510978
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Entry
100510978 CDS
T01009
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc04140
Autophagy - animal
ssc04141
Protein processing in endoplasmic reticulum
ssc04210
Apoptosis
ssc04932
Non-alcoholic fatty liver disease
ssc05010
Alzheimer disease
ssc05012
Parkinson disease
ssc05014
Amyotrophic lateral sclerosis
ssc05016
Huntington disease
ssc05017
Spinocerebellar ataxia
ssc05022
Pathways of neurodegeneration - multiple diseases
ssc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100510978 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100510978 (ERN1)
09143 Cell growth and death
04210 Apoptosis
100510978 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100510978 (ERN1)
05012 Parkinson disease
100510978 (ERN1)
05014 Amyotrophic lateral sclerosis
100510978 (ERN1)
05016 Huntington disease
100510978 (ERN1)
05017 Spinocerebellar ataxia
100510978 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
100510978 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100510978 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100510978 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
100510978 (ERN1)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100510978 (ERN1)
Protein kinases [BR:
ssc01001
]
Serine/threonine kinases: Other
IRE family
100510978 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Band_3_cyto
Motif
Other DBs
NCBI-GeneID:
100510978
NCBI-ProteinID:
XP_005668752
Ensembl:
ENSSSCG00000017279
UniProt:
A0A5G2R3T9
LinkDB
All DBs
Position
12:14881913..14963290
Genome browser
AA seq
973 aa
AA seq
DB search
MPGRLLLLLALLLPGPGGFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPV
LQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKK
QDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKARELRWNATYFD
YAAALPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVM
HINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVH
EGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFNPGLKGKNKLNYLRNYWLL
IGHHETPLSASTKVLERFPNNLPKHRENVIPADVDKKSFEEVIDLVDQSSENAPTVVSQD
VEEKFSHAPAKPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQQQQQQFQK
ELEKIQLLQQQQLPFHPPGDAAQDAELLDSLGQYSESSGTSSPSTSPRASNHSLHSSGSA
SKAGTSPFLEQDDEDEESSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRHVAVKRILP
ECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGL
EPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRH
SFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVVSEGSHPFGNSLQRQA
NILLGAYSLDCLHPEKHEDVIARELIEKMISMDPQKRPSAKHVLKHPFFWSLEKQLQFFQ
DVSDRIEKESLDGPIVQQLERGGRAVVRMDWRENITVPLQTDLRKFRTYKGGSVRDLLRA
MRNKKHHYRELPVDVQETLGTLPDGFVRYFTSRFPHLLAHTYRAMELCRHERPFQPYYHE
PPEPRPPVTPDAL
NT seq
2922 nt
NT seq
+upstream
nt +downstream
nt
atgcctggccggctgcttctgctgctggcgttgctgctgcccggtcccgggggttttgga
agtcccagcactgtgacacttcctgagaccttactgtttgtgtcgaccttggacggaagt
ttgcatgccgtcagcaagaggacaggctccatcaaatggactttaaaagaagatccagtc
ctgcaggttccaacgcatgtcgaagagcctgccttcctcccagatcccaatgatggcagc
ctgtatacacttgggggcaagaataatgaaggcctgacgaaacttccctttacgatccca
gagttggtgcaggcatccccgtgccgaagttcggatggaattctctacatgggtaagaag
caggacatctggtatgtaattgacctcctgaccggagagaagcagcagactttgtcatcg
gcctttgcagacagtctctgcccatcaacctctcttctgtatcttgggcggacagagtac
accatcaccatgtacgacaccaaagcccgcgagctccgctggaacgccacctacttcgac
tacgcggccgcgctgcccgaggacgacggggactacaagatgtcccactttgtgtccaat
ggcgacgggctggtggtgaccgtggacagcgaatccggggacgtcctgtggatccaaaac
tatgcctcccccgtggtggccttttacgtctggcagcgggagggcctgcggaaggtgatg
cacatcaacgtggccgtggagaccctgcgctacctgaccttcatgtccggggaggtgggg
cgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctcacg
cccaccctgtatgtggggaaatattccaccagcctctatgcgtcgccctcaatggtacat
gagggggtcgccgttgtgccccgaggcagcactcttcctctgctggaaggtccccagacc
gacggtgtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctgaag
ttcaacccaggacttaaagggaagaacaagcttaactatctgaggaactactggcttctg
attggtcaccacgaaaccccgctatccgcgtctaccaaggtgctggagagattccccaac
aatctgcccaaacaccgggaaaacgtgattcctgccgacgtggacaagaagagctttgag
gaggttatcgacctggttgaccagagctcagaaaacgcccccaccgtggtgtctcaggat
gtggaagagaagttctctcacgccccggccaagcccgaggcccccgtggactccatgctc
aaggacatggccaccatcatcctgagcaccttcctgctcattggctgggtggccttcatc
atcacctaccccctgagcatgcaccagcagcagcagcagcagcagcagcagttccagaag
gaactagagaaaatccagctcctgcaacagcagcagctgcccttccatccacccggagac
gcggctcaggatgccgagctcctagactcgttgggccagtactcagagagctcgggcacc
agcagccccagcacgtcccccagagcctccaaccactcgctgcactccagcggctctgcc
tccaaggcgggcaccagccccttcctggagcaggacgacgaggatgaggaaagcagcatg
gtgatggttgggaaaatctctttctgtcccaaggacgtcctgggccacggagccgagggc
acaatcgtgtaccggggcatgtttgacaaccgccacgtggccgtcaagaggatcctcccc
gagtgtttcagtttcgccgaccgcgaggtccagctgctgcgagagtcggacgagcacccg
aacgtgatccgttacttctgcacggagcgggaccggcagttccagtacatcgccatcgag
ctgtgcgcggccactctgcaggagtacgtggagcagaaggacttcgcccacctcggcttg
gagcccatcaccttgctgcagcagaccacctcgggcctggcccacctgcactccctcaac
atcgttcacagagacctgaagccccacaacatcctgctgtccatgcccaacgcccacggc
aggatcaaggccatgatctccgacttcggcctctgcaagaagctggcggtgggcaggcac
agcttcagccgccgctcaggggtgcccggcacagaaggctggatcgccccagagatgctg
agcgaagactgcaaggagaaccccacctacacggtggacatcttctccgccggctgcgtc
ttttactacgtggtgtctgagggcagccaccctttcggcaattccctgcagcgtcaggcc
aacatactcctgggcgcctacagcctcgactgcctgcaccctgagaagcacgaagacgtc
attgcccgggaactaatagagaagatgatctccatggaccctcagaagcgcccgtccgcg
aagcatgtgctgaaacacccattcttctggagcctagagaagcagctccagttcttccag
gacgtgagtgaccggatagagaaggagtccctggacggccccatagtgcagcagctggag
cggggcgggcgggccgtggtgaggatggactggcgggagaacatcaccgtccccctccag
acagacctgcgcaaattccgaacctataaaggcggctctgtccgagacctcctccgggcc
atgagaaataagaagcaccactaccgggagctccccgtggacgtgcaggagacgctgggc
accctccccgacggcttcgtgcgctacttcacctcgcgcttcccccacctcctggcacac
acctaccgcgccatggagctgtgccgccacgagaggcccttccagccctactaccacgag
cccccagagccgcggcccccggtgactccagacgccctctga
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