Sus scrofa (pig): 100511239
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Entry
100511239 CDS
T01009
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100511239 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
ssc03021
]
100511239 (SETX)
Enzymes [BR:
ssc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
100511239 (SETX)
5.6.2.5 RNA 5'-3' helicase
100511239 (SETX)
Transcription machinery [BR:
ssc03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
100511239 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
SEN1_N
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
ResIII
SLFN-g3_helicase
AAA_16
Helicase_RecD
UvrD_C_2
TniB
Motif
Other DBs
NCBI-GeneID:
100511239
NCBI-ProteinID:
XP_013842495
Ensembl:
ENSSSCG00000005724
LinkDB
All DBs
Position
1:complement(272093449..272170857)
Genome browser
AA seq
2670 aa
AA seq
DB search
MSTCCWCTPGGASTVGFLTRYASRTRSSEFQTADEDLCYCLECVAEYHKAREELPSLHET
LWELETVRLINHFEKSMKAEIEDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLERPEIYTTSVLEKGKLILLPSHMYDTTNYKSYWLG
ICMLLTILEEQAMDSLLLGPDKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNGSYNREIQNIRNSSVRMKLEPESYLDDMVTCSQIVYNFN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDGVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSVPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKQFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKVKVP
QCSTFVDVTPACKTPPASCNKEEHEHKGKKSVKDRHCLESSSPAFSKDPMKADACQGQEG
ILSKASNAVEEGNEQNCMKGLKPEDRLSPESCLKQSSKNYFPERTQEQVKKSTRKHKSVK
ENSSHTPQNCTSRSGPESVFDRGPAPSTRLSTDSLEKVSTSNEGFSLRDDALGRSSKGKS
KAQKNEVCAKLSHVMKKQHKNSGPVSTAVTVDDSLSVPSLERVHSKKDAGGQKGDGFIHS
LSNGILDDKHGEQKSQDNSSLPKKKQIKKEEELDLFSTPENNCQIQEYHVGKDLVSFAET
TDTFMNKTPPFKDPVTLLELTDKEISKSTSQFCSVLREQTPGISPKSDTLTDSQVDRDLH
KYSLLAQASATKFPSDSTQKSSSQLQRKVKDEKRCLRANQNNGESSHGQIIIISDSDDDG
DDERILGFEKHIKQDKTCTEKDRPEQRTPGANTNVEQKVIKEENTGSPLQFEESDSQFFE
FESPYEVFSVWQDGKPDKNSVQQDEKNSCLTYTGDITNDWGYDTDYIYEQVSREVEGVEQ
AEPQSSSVSVKEFYEIDVKKPKRKRYENPVAEDPVRPSSSIRKEGQSDTERDLPENGLKS
TDKRTRADASVTRATEVSLKKSSKPRTHSKPIRRVPLSETPKKTHAETKKGQSKSSNYLS
CRTTPAVVPAKKFRKCPEPTSIAEKLGLKKRPRKAFELSQPSLDSLAQLRDHGKTVGAVD
TQRKTKLIAAQSLSVKNNKKLLTNQDLQFRRQVRPKAQQNRQGPFDPENADAARAGPQAA
QNSGIFVPASDRSDYSSKGGAEVTANRSGKQLIKCASSEPEPIKAKRASPAPDDTCPLNQ
ENPIVLNGRKPTNEIVASTSEDPLGGGDLIATLKSEGEPECNSDIEEDDIFLTQRDPEDM
DLCSQMEEGNAQLIEVVHGKDTVQVEEDSRSRPQLESLSSAKCKYKDCVETMKNQGEYCS
KHSEAKAADEDVFRKPGLPLSASKPSRPSTTKIFSSRTTSRIANLSKSLENASALPPTLR
NKSNGVQPISKVLQPASLMSPKPMGEVKNLSNVPYSQAPSASNRQGYRGAFGESKSFPAS
SAVSILLSSQSISDAFVKEVLKWKYEMFVNFDQCGPPSGLCQAIARRVPVRFQDCGDYFS
VFFPLMILNTFETVFQWSFKRNVAQEWISSPNKEKFHQLHLRKFPADYKKYWEFVVYLEE
CELAKQLHPKENDLVFLVPERLNGEKDVERNRAHSPREYHCGYVHKFRRTSVMRSGKSEC
SLSIQTQDKLPVNLNEFVKCVVISSLVTTQRKLKAMSLLSGRNQLARAILNPNPMDFCTK
DLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLL
YRLLTENQRRGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKRNPLGN
CGDINLVRLGPEKSINNEVLRFSLDSQVNHRMKKDLPSYVQEMHRRKEFLDHQLDELSRQ
RALCRGGREMQRRELDGKIAEVSKERQELASKIKEVQGRPQKTQNTIILESHIICCTLST
SGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLVLVGDPKQLPPTVIS
MKAQDYGYDQSMMARFYKLLEENVEHNVIGRLPILQLTVQYRMHPDICLFPSNYIYNRNL
KTNSLTEASRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEIIKLIKDKRRDV
TFRNIGIITHYKAQKTLIQKDLDKEFDRKGPAEVDTVDGFQGRQKDCVIVTCVRAKTSQG
SIGFLASLQRLNVTITRAKYSLFILGHLRTLRENDHWNQLIEDAQKRGAIIKTCDKNYRH
DATKILKPKPVLQRSLTHPPTIGLEASPDGEFSRTAVASSLYHSPSDCRDATVTASDPER
PPIQDRLRDPRLLRRMGLSPEAKGRCSREPQPSSPQQPGAAPPPGEAGFSGSLQDPAGPG
QQPTAKGAAPNLHRPQAQGEPAAAGADASTSKRKCDPEEGSLSHRRETRAFSEGGPERRG
SVRHHAGRDLGSDEWGPQKEDGGWKKRRLS
NT seq
8013 nt
NT seq
+upstream
nt +downstream
nt
atgagcacctgttgctggtgtacaccgggtggtgcttccaccgtaggcttcctgacacgc
tatgcatccaggacccgctccagtgaatttcaaacagccgatgaagacctctgctactgc
ttggagtgtgtggctgaataccacaaagcaagggaggagttgccctccttacatgagact
ttatgggaactagaaaccgtacgtctcataaatcactttgaaaaatccatgaaggccgaa
attgaagatgatgacgagttatatatagtggacaacaatggagaggcacagctgtttgac
ttcactggccaagactttgaaaataagcttcgagttccacttctggaaatactgaaatat
ccttatctgcttttgcatgagcgtgttaatgaattatgtgttgaagcactttgccggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccagggatctatttattcctg
gtccaccccaatgaaatggtgcggcgttgggctatcctgacggcaagaaacctggggaaa
gtggacagagatgattattatgacttgcaggaggttttgacttgcctgtttaaagtcatc
gagttggggcttttagaacgtcctgagatttataccacttctgtccttgagaagggcaaa
ctgattcttctgccctcgcacatgtatgatactaccaactacaaaagctattggttaggg
atttgcatgttgctgaccattcttgaggagcaagccatggattcactgttgttgggccca
gacaaacaaaatgactttatgcaatcaatacttcacaccatggagagacaatcagatgat
gatagtgtggatcctttctggccagcattacactgtttcatggtgattctggatcgtctt
ggatctaaggtctggggtcaacttattgatcctattgaggcatttcaaaccattatcaac
aatgggagctacaacagagagatccaaaacatacggaacagctctgtgaggatgaagtta
gaaccggagtcttacttggatgatatggtgacttgcagccagattgtgtacaattttaat
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagactattgtcct
aacatgtatgaggaaatggaaacattagctaacgtgctgcagtcggatattggtcaagac
atgcgagttcacaacagcaccttcctgtggttcattcctttcgttcagtccctcatggat
cttaaggacctgggtgtggcctacatcgtggaggttattcaccacctgcactcggaagtc
aaagacgtcctcaaccagacggacggggtgtgtgacaaggtcaccgagttcttccttctc
attttggtgtcggtgattgaactgcatcgaaataaaaaatgtttgcatttgctgtgggtt
agttcgcagcagtgggtggaagccgttgtaaagtgcgccaagcttcccaccaccgcgttt
gcacggagttctgagaagtcgtctgggaactgctccaaaggaacagcaatgatatcatct
ctgtcattgcactcagtgccatctaactctgtgcagcttgcttgtgtgcagctgattaga
agtctcctaaaagaaggttatcagctggggcagcagactctttgtaagcaattctgggat
aagctcaacttattcctacgaggaaatttatctttaggttggcagttgactagtcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacataaaagtcaaagtacct
caatgcagcacttttgtggatgtgactcctgcatgtaaaactcctcctgcatcttgtaat
aaagaagagcatgaacacaaagggaagaagtctgtgaaagacaggcactgtctggaaagt
tccagcccagcattttctaaagacccaatgaaagctgatgcatgtcaaggccaagagggt
attttgagcaaagcaagtaacgctgtagaagagggtaatgagcaaaactgtatgaaaggt
ttgaaaccagaagatcgtctttcacctgagtcgtgcttaaagcagagtagtaaaaactat
tttcctgaaagaacgcaagagcaagttaaaaagagtacaaggaagcataagtctgtaaaa
gagaattcctcgcatacaccacagaattgtacttcgagaagtggtccggaaagtgtgttt
gacagaggaccagcaccatcaacacgcttgtcgactgattctctggaaaaggtgtccaca
tcaaatgagggtttctctctaagggatgatgctcttggcagaagctccaaaggaaaaagt
aaggcacagaaaaatgaggtgtgcgccaagttgtcacatgtaatgaaaaagcaacacaag
aatagtggccctgtcagtactgctgtcactgtagacgacagcctgagcgtgcctagcctt
gagcgcgtccattcaaagaaagatgcgggagggcagaaaggagatggcttcatacacagt
ctctctaatggtattctggatgataaacacggagaacagaagtctcaagacaacagttca
ttgccaaaaaagaaacaaataaagaaagaagaagagttagatcttttctctacccctgaa
aacaattgtcaaatacaggaatatcacgttggtaaagatttggtctcatttgcagaaacg
accgatactttcatgaacaaaacacctccctttaaggatcccgtgacgctacttgaattg
acagataaggaaattagcaagagtaccagtcagttttgttctgttttaagagagcagacc
cctggcatcagtcctaagtctgacaccttaacagattctcaggtagacagagacctccac
aaatactctttgctagctcaagccagtgctactaagtttccatcagattcaactcaaaaa
agttcatcccagctacaaagaaaagtaaaagatgagaaaagatgtctcagagctaaccaa
aataatggggaatccagccatggacagattattattatttcagattctgatgatgatggt
gatgatgaaagaattctaggttttgagaaacacataaaacaggataaaacatgcactgag
aaagaccgcccagagcagcgcactccaggagcaaatacaaatgtggaacagaaggtaata
aaggaagaaaatacaggatcccctttgcagtttgaggaatctgattctcagtttttcgag
tttgaaagtccatacgaagtgttttcagtttggcaagatgggaaaccagacaagaattca
gttcaacaggacgaaaaaaattcatgcttgacttacacaggtgatatcacaaatgattgg
ggttatgatacagattatatatatgaacaggtcagtagagaggtagagggcgttgaacag
gcagaaccacagagcagcagtgtttctgttaaggaattttatgaaattgatgtaaaaaaa
cccaagcgaaaacgatatgaaaatcctgtggctgaagatcctgtaaggccttcctcttct
atcagaaaggagggccagtctgatacggagagagatctgcctgaaaatggtcttaaaagt
acagacaaaaggactagagcggatgcaagtgttacgagagccactgaggtttctctaaag
aagtcttctaagcctcgcactcactccaaacctatcaggagagtcccactttctgaaact
ccaaagaaaacacatgcagagactaaaaaagggcagagtaaaagttcaaattacctaagt
tgtagaaccactcctgctgtagtgccagcaaagaaatttcgcaagtgtcctgaacccact
tcaatagcggagaagcttggtctgaaaaagcgtcctcgtaaggcattcgagttgtcacag
ccatctttagatagtttggcgcaattacgggaccatggcaaaactgtcggagcggttgat
acccagagaaagaccaagttaattgctgctcagtctctgtctgtcaaaaacaataagaaa
ctgctgacaaatcaagaccttcagtttcgaaggcaggtgagacccaaagcacaacagaac
agacaaggaccctttgatcctgaaaatgcagatgctgccagagcagggccacaggcagcc
cagaattctggcatatttgtaccagcatcagataggtcagattatagttccaaaggagga
gccgaggtcactgctaacaggagtggaaaacagttaataaaatgtgcatcttctgaacca
gaacctataaaagcaaaacgtgcttcgccggcacctgatgacacttgtcctttgaaccag
gaaaatcctatagtgttgaatggaagaaaaccaacaaatgaaatagttgcctctacttca
gaggaccctttaggtggaggtgacctaatagcaactttgaaatcagagggagagcctgaa
tgcaacagtgacatagaggaagatgatatatttttaacacagcgtgatcctgaagatatg
gacttatgttcacaaatggaggaagggaacgctcaactcattgaagtagttcatggaaaa
gatacagttcaggtcgaggaagattctaggagtcggcctcagttggaatctctgagtagc
gcaaaatgtaagtataaagattgtgttgaaacgatgaaaaaccagggtgaatactgctca
aagcactctgaagccaaagcagcagatgaggatgtatttcgtaaacccggcctgcctctt
tctgcatctaaaccttccagaccttccactactaagatttttagctcaaggactacttca
cgaattgctaatctttccaagtctttggaaaatgcctcagcacttccaccaactctaaga
aataagtccaatggggtacagcctatttcaaaagtactgcagccagcctctctgatgtct
ccgaagccaatgggtgaggtgaagaacttgagcaacgttccctattctcaggctccaagt
gcttccaacaggcaaggttacagaggtgcatttggtgagagcaagtctttcccggcttcc
tctgccgtcagcattctcctgtcatcacagtccatctccgacgccttcgttaaagaggtc
ttgaagtggaagtacgagatgtttgtcaactttgatcagtgcgggcccccatcaggtctt
tgtcaggccatcgcgagacgtgtgcctgtcaggttccaagactgtggagattattttagc
gtgtttttccctttgatgatactgaatacttttgaaacagtgtttcagtggagtttcaag
aggaatgtggcacaggagtggatcagctctccaaataaagagaaattccatcagttgcat
ttacgaaaatttcctgctgattataaaaaatactgggagtttgtggtttaccttgaggaa
tgtgaacttgctaaacagcttcacccaaaggaaaatgatctggtgtttttggttcctgaa
agactgaatggagagaaggacgtagagagaaaccgtgcgcacagcccccgtgaatatcac
tgcggttatgttcataagttccgccgcacttcagtcatgcgcagtgggaaatctgagtgc
tccctgtccatccagactcaagataagttaccagtcaatttaaatgaattcgtgaaatgt
gttgtcatcagctctctggtaaccacgcaaaggaagttgaaagccatgtctttgctgagc
ggtcggaaccaactggccagagccattctgaatccaaaccccatggacttctgtacaaaa
gatttactgacgacaacatctgagagaattattgcctacttaagagatttcaatgaagac
caaaagaaggccatagaaactgcgtatgccatggtgaaacactccccttccgttgccaag
atctgtctgattcatggaccacctggaaccggaaaatccaaaaccatcgttggcctcctg
taccgcctgctgacagagaaccagaggagggggcactcagatgagaactccaatgccaaa
atcaaacaaaaccgtgtccttgtgtgtgcgccttccaatgccgctgttgatgaacttatg
aaaaaaattatcctcgaattcaaagaaaaatgtaaagacaagaggaatcctttgggaaac
tgtggagatataaatttagtacgtctaggtccagaaaagtctattaataacgaggtccta
agattcagtttggacagccaagttaaccacagaatgaaaaaagacttaccttcctatgtt
caagagatgcatagaagaaaggaatttctagatcatcagctagatgaactttcccgccag
cgtgctttatgccgagggggaagggaaatgcagaggcgagaattagatggaaaaatcgcc
gaagtttcaaaagaaaggcaagaacttgcttctaaaattaaagaggttcaaggacgccca
cagaaaacccagaataccatcatcctagagtcgcacatcatctgctgcacgctgagcacg
agcggtggtttgctgctggagtccgcttttcgcgggcaggggggtgtccccttcagttgt
gtcattgtcgatgaggccgggcagtcttgcgaagtggaaactctgactccactcatccat
cgttgcaacaagcttgtcctcgtaggggatcctaagcagctccctcccacggtcatttct
atgaaggcccaggactacggctatgaccagtcgatgatggcccgtttctacaaactgctg
gaggagaacgtggagcacaacgtgatcgggcgactgcctattctccagctcaccgttcag
tacaggatgcatcccgacatctgtctcttcccttctaactacatctataacagaaacctg
aaaacaaacagcttgacggaggccagccgctgttcgtcagactggccgtttcagccctac
ctcgtgtttgacgtcggggacggctccgaacgacgggataacgactcatatgtaaatgtg
caagaaataaaactggtaatggaaataattaaacttattaaagacaaaaggagggatgtt
actttccgaaacattggcataataacccattacaaggctcagaagacgctgattcagaag
gatttggacaaagagtttgatagaaaagggccggcagaagtagacaccgtggatggattc
cagggtcgtcagaaggattgtgttattgttacatgtgtgagagcaaagacctcacaaggc
tccatcgggtttctggcaagtttgcagagattgaatgtcaccatcacacgagccaagtac
agcctcttcatcctcggacatttgaggaccctgagggaaaacgatcattggaatcagctg
atcgaggatgcgcagaagcgtggcgccattattaagacttgcgacaaaaattacagacat
gacgcaaccaagattctgaaacccaagcccgtactgcagagaagtctgactcaccctccc
accatcggcctggaggcgtccccagacggcgagttttccaggacggctgttgcttcttcc
ctgtaccactctccctctgactgcagagacgccacggttactgccagtgaccctgaaagg
ccacccattcaggaccggcttcgggacccgcgactgctgaggcggatgggcctgagccct
gaagccaaagggagatgctcaagggagccacagccctcgagcccccagcagcctggggca
gcgccccccccgggagaggcgggcttctctggaagtctccaggatcccgccggtcctggg
cagcagcccaccgccaaaggagcggctccgaacctccacagacctcaggcgcagggcgag
cctgcagccgctggtgcggacgcttccacgagcaaaagaaaatgtgacccggaggagggc
tcgctcagccacagaagagagaccagggctttcagcgaagggggtccggagaggcgaggc
tctgtgcgccaccacgcggggagggacctgggctcggacgagtgggggccgcagaaggag
gacggtggctggaagaagagaaggctttcatag
DBGET
integrated database retrieval system
