Sus scrofa (pig): 100620652
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Entry
100620652 CDS
T01009
Symbol
GART
Name
(RefSeq) LOW QUALITY PROTEIN: trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc00230
Purine metabolism
ssc00670
One carbon pool by folate
ssc01100
Metabolic pathways
ssc01523
Antifolate resistance
Module
ssc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100620652 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100620652 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100620652 (GART)
Enzymes [BR:
ssc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
100620652 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
100620652 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
100620652 (GART)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
RimK
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
100620652
NCBI-ProteinID:
XP_020926604
Ensembl:
ENSSSCG00000030677
LinkDB
All DBs
Position
13:complement(197130898..197158797)
Genome browser
AA seq
1018 aa
AA seq
DB search
MAAQVLVIGNGGREHTLAWKLAQSNHVKQVLVTPGNAGTASSEKISNTDVSVSDHAALAQ
FCKEEKIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIIAESKEEACKAVQEIMQDRAF
GEAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLDGDHGPNTGGMGAYCPAP
QVSKDLLLKIKDTILQKTVAGMQQEGVPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQATLDGRLCTSLPVWHDNRAAVTVVMASKGYPGDYTKGVEITGFHEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIQENLISALEEAKKGLAAIKFEGAIYRKD
IGCRAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFSDPLLACGTDGVGTKLKIAQQCHKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNTTEAVVAGIAEACKKAGCALLGMIIHFNHTGXNAEMPDMYPPGEYDLAGFAVGA
MERDQKLPHLERITEGDAVIGVASSGLHSNGFSLVRKIIAKSSLQYSSPAPDGCGDQTLG
DLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDARTWRIPRI
FSWLQQLGHLSEEEMARTFNCGIGAALVVSKDLTEQILQDIERHKEEAWVIGKVVACPEG
SPRVKVKHLIESMQINGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIESTQAPS
SSAHIIVVISNKAAVAGLDKAARAGIPTRVINHKLYKDRVAFDMAVDQVLEEFSTDIVCL
AGFMRILSGPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDA
GQIVLQEAVPVKRGDTIETLSERVKLAEHKIFPSALQLVASGTVQLGENGKIRWVREE
NT seq
3057 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccaagtacttgtaattggcaatggaggaagggaacatacactggcctggaaa
cttgcacagtctaatcatgtcaaacaagtgttggttaccccgggaaatgccggcactgcc
tcctccgaaaagatttcaaatactgatgtctccgtcagtgatcatgctgcccttgctcag
ttctgcaaagaggagaaaattgagtttgtagttgttggaccagaggcacctctggctgct
ggaattgttgggaacctgacatctgcaggagtacggtgctttggccccacagcagaagca
gctcagttagagtccagcaaaagatttgccaaagagtttatggatcgacatggaatccca
acggcacaatggagagctttcaccaaacctgaagaagcctgtagcttcattatgagtgca
gatttccctgctttggttgtgaaggccagtggtcttgcagcagggaaaggggtgattatt
gcggagagcaaagaagaggcctgcaaagctgtacaggagatcatgcaggatagggctttc
ggagaagctggagaaacaattgtcattgaagaacttcttgaaggagaagaggtgtcttgc
ctgtgcttcactgatgggaggactgtggcccccatgcccccagcacaggaccataagcga
ttgctggatggagatcatggccccaacacggggggaatgggagcctattgtccagcacct
caggtttctaaggatttgttgctaaaaattaaagatacgattcttcagaagacagtggct
ggcatgcagcaggagggtgtcccatacacaggtattctctatgctggtataatgctgacc
aagaatggtccaaaagttttggagtttaactgccgtttcggtgatccagagtgccaagtg
atcctcccgcttctgaaaagtgatctttatgaagtgatccaggctaccttagatggtaga
ctgtgcacatctctgcctgtttggcatgacaaccgcgctgccgtaactgtggtcatggca
agtaaaggttatccaggagactacaccaagggtgtagagataacagggtttcatgaggct
caagctttaggactggaggtgtttcaagcaggcactgccctaaaagatggcaaagtggtg
actaatgggggtagggtccttacggtaacggccatccaggaaaatctcatctcagccctg
gaagaagccaagaaaggactcgctgctataaagtttgagggagccatttataggaaggac
attggctgtcgtgccatagctttcctccagcagcccaggggcctgacgtacaaggaatct
ggggtagacattgcagctggaaatatgctggtcaaaaaaattaagccattagcaaaagcc
acttccagaccaggttgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcagtgatcctcttctagcctgtgggacagacggcgttggaaccaaactg
aagattgcccagcagtgccataaacatgataccattggtcaagatttggttgcaatgtgt
gtaaatgatattttggcacaaggagccgagcccctctttttcctcgattacttttcctgt
ggaaaacttgacctcaatacgacggaagctgttgtggctggaatcgctgaagcttgtaaa
aaagccggatgtgctctcctcggtatgatcatccattttaatcacacggggtgaaacgca
gaaatgcccgacatgtaccctcctggagagtatgacttagccggttttgccgttggtgcc
atggaacgagatcagaaactccctcatctggaaagaatcacggaaggggacgctgttatt
ggagtggcttcatctggtcttcacagcaatggatttagccttgtgaggaaaatcatagca
aaatcttccctccagtactcctctccagcacctgatggctgtggtgaccagaccttgggg
gacttacttctgactccgaccagaatctacagccattcgctgttacctgtactacgctcg
ggacatgttaaggcctttgcccatattactggtggaggattgctggaaaacatccccaga
gtcctccctcagaaatttggggtggatttagacgcccggacctggaggatccccaggatc
ttctcctggttacagcagctaggacatctctcagaagaagagatggccagaacatttaac
tgtgggattggggctgccctcgtggtgtcaaaggatctgacagagcagattctgcaagat
attgagcggcataaggaagaagcctgggtgattggcaaggtggtagcgtgtcctgaaggt
tctcctcgtgtgaaagtcaagcatctgattgaaagcatgcaaataaatggatcagtgttg
gagaatggcaccctgaaaaatcatttctctgttcaaccgaaaaaggcaagagtagctgtc
ttaatatctggcacaggatcgaacctccaagccctcatcgagagcactcaggcaccaagt
agctctgcacacatcattgttgtgatctccaacaaagcagcagtggccggcttagataaa
gcagcaagagccggcatccccaccagggtaattaatcacaaattatataaagatcgtgta
gcattcgacatggcagttgaccaagtccttgaagagttctccacagacatagtctgtctt
gcaggattcatgagaattttatctggcccctttgttagaaaatggaatgggaaaatgctc
aacatccacccatccttgctcccttcatttaagggttcaaatgcccatgagcaagtcctg
gatgccggggtcacggtcactgggtgcactgtgcatttcgtagctgaggatgtcgatgct
ggacaaattgttttacaagaagctgttccagtgaagaggggagacaccattgaaactctc
tctgaaagagtaaaattagcagagcataaaatatttccctcagccctccagctggtggcc
agtggcactgtacagcttggagaaaatggcaagatccgttgggtcagagaggaatga
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