KEGG   Sus scrofa (pig): 100626911
Entry
100626911         CDS       T01009                                 
Symbol
SHMT2
Name
(RefSeq) LOW QUALITY PROTEIN: serine hydroxymethyltransferase, mitochondrial
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00260  Glycine, serine and threonine metabolism
ssc00630  Glyoxylate and dicarboxylate metabolism
ssc00670  One carbon pool by folate
ssc01100  Metabolic pathways
ssc01200  Carbon metabolism
ssc01230  Biosynthesis of amino acids
ssc01240  Biosynthesis of cofactors
ssc01523  Antifolate resistance
ssc04981  Folate transport and metabolism
Module
ssc_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    100626911 (SHMT2)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    100626911 (SHMT2)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100626911 (SHMT2)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100626911 (SHMT2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100626911 (SHMT2)
Enzymes [BR:ssc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     100626911 (SHMT2)
SSDB
Motif
Pfam: SHMT
Other DBs
NCBI-GeneID: 100626911
NCBI-ProteinID: XP_020947486
Ensembl: ENSSSCG00000021493 ENSSSCG00000022116
LinkDB
Position
5:22535780..22540322
AA seq 483 aa
MAIRSQHSEAAQTQTGEATKGWSGQESLSDSDPEMWELLRREKDRQCRGLELIASENFCS
RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY
SGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMTDVKRISATSIFFESMPYKLNPKT
GLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA
KVIPSPFEHADVVTTTTHKTLRGARSGLIFYRKGVRTVDPKTGREIPYTFEDRINFAVFP
SLXGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL
VLVDLRPKGLDGARVERVLELVSITANKNTCPGDRSAITPGGLRLGTPALTSRQFREDDF
RKVVAFIDEGVSIGLEVKSKTTKLQDFKSFLLKDPETCRRLADLRQRVEQFARAFPMPGF
EEH
NT seq 1452 nt   +upstreamnt  +downstreamnt
atggccataaggagccagcacagcgaggcggcccagacccagactggagaagcaaccaag
ggctggtcaggccaggagagtctatcagacagtgaccctgagatgtgggagctgctgcgg
agagagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgcagc
cgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttatcct
ggcaagagatactatggaggagccgaggtagtggatgaaatcgagctgctgtgccagcgc
cgggccttggaggcctttgacctggatcctgctcagtggggagtcaatgtgcagccctac
tcggggtccccagccaatctggctgcctacacagcccttctgcagcctcacgaccgaatc
atggggctggacctgcccgatgggggccatctcacccatggctacatgaccgatgtcaag
cggatctcagccacatccatcttctttgagtctatgccctataagctgaatcccaaaact
ggcctcattgactatgaccagctggcactcactgctcggctcttccggccgcgactcatc
atagctggaacgagtgcctatgcacgcctcatcgactatgcccgcatgagagaggtgtgt
gatgaggtcaaggcacacctgctggcagacatggcccacattagtggcctcgtggctgcc
aaggtgatcccctcaccttttgagcatgcggatgttgtcaccaccaccactcacaagacc
cttcgaggggccaggtcaggactcatcttctaccggaagggtgtgcggactgtggacccc
aagactggccgggagatcccttacacgtttgaggaccgaatcaactttgctgtgttccca
tccctgncagggggcccccacaaccatgccatcgctgcagtggctgtggccttaaagcag
gcctgcacccccatgttccgggagtactccctgcaggttctgaagaacgctcgggccatg
gctgatgccctgctagagcgaggctactcgctggtgtctggcggcactgacaaccactta
gtgctggtagacctgcggcccaagggcctggatggagctcgagttgagcgggtgctagaa
cttgtgtccatcacggccaacaagaacacctgtcctggagatcgaagtgccatcactcct
gggggcctgcggctggggaccccagccttgacgtcacgccagttccgtgaggatgacttc
cgaaaagttgtggcctttatagacgaaggcgtcagcatcggcttggaggtgaagagcaag
accactaaactccaggatttcaaatccttcctgctcaaagacccagaaacgtgccgtcgg
ctggctgacctcaggcaacgggtggagcagtttgccagggccttccccatgcctggcttt
gaggaacactga

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