Sus scrofa (pig): 100738665
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Entry
100738665 CDS
T01009
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc00310
Lysine degradation
ssc01100
Metabolic pathways
ssc05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
100738665 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
100738665 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ssc03036
]
100738665 (DOT1L)
Enzymes [BR:
ssc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
100738665 (DOT1L)
Chromosome and associated proteins [BR:
ssc03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
100738665 (DOT1L)
HMT complexes
Dot1-containing complex
100738665 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
100738665
NCBI-ProteinID:
XP_020939844
Ensembl:
ENSSSCG00000013457
LinkDB
All DBs
Position
2:76339452..76401974
Genome browser
AA seq
1720 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTPVDSGAEEEKAGATTIKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSST
NPERKPKKTQSALDLLHAQTVSRAASPSPQDAHRPPHSPFYQLPPSVQRHPPEQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKGNRELRSRSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDTLSAHLRGRGGLAREPEAEPGRLRLELDCAKFSLPHFSSTSPELSMNGHAASY
ELCSALSRPSPKQNTPQYLTSPLDQEVVPCTPSHGGRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHVAGNKAATSDLHPRVEPTKENGLPYHSPGITNGIKLSPQDPRPSSPTGLQM
TGEKGSEKGVRERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPGPQARETSTTLEKQMGANAHGAGGSAAGGKGLALPPTGFTYAGSMAISGTLAGSPVP
LAPGAEPPALDESSSSGSLFATMGSRSSTPQHPPLLTQPRSCGSASPAPQLCTSPRLATQ
GPLPDASKGDLPAEAGFSDPESEAKRRVVFTIAAGAGSAKQSPSSKHSPLPSGTRGDSGQ
SHGQDSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQP
LEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGS
ARIERKIATISLESKSPPKTLENGGGLAGRKVPPASEPVNSSKWKSTFSPISDLGLSRAA
DSPLQASSTLSHSSLFAFRPSLEEPSSADTKLAAHSRKSFSGTLPAAGGLSPSSHPASGF
ALGGGLATDLSLHSFSDGASLSHKAPEAAGLGAPLSFPAPRGKEGGASEPGPFSNKRQLD
GLGPKGEGGLPTCGPTDKASLVHSKAGKGRDREPDVKNGHNLFMAAATAPPGGLLSGPGL
TPAVSSAGSTAPATQTHRPFLGAFAPSPQFTLGPMSLQANLGPSVLQSLFSSVPAAGLVH
GSSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPPASAHPFGASFGSGAACRSATLSLT
PLQAVASTPASSFQAPSSAEPRPPPPPPHLGRPPPGQPALHAPPPPNAALPPPPALLPAN
SEPVLLQNLASLPANQAFLPASSAASLPPANASVSIKLASLPHKVSRPSFTVHHQPLPGL
ALAQATPMIPQASSTGPPAVWVSLGMPPPYAARLAGVKPR
NT seq
5163 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgataaacaccacgatgctgctcacgaaatcatcgagact
atccgatgggtctgtgaagaaatcccagatctcaagcttgctatggagaattatgtttta
atcgactacgataccaaaagctttgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacacg
cggccatccactggactcctgcgccacatcctgcagcaggtctacaaccactcggtgact
gaccccgagaagcttaacaactatgagcccttctccccggaggtgtatggggagacctcc
ttcgacctggtcgcccagatgatcgatgaaatcaagatgaccgaggatgacctgtttgtg
gacctgggcagcggagtgggccaggtcgtgctgcaggtcgccgcagccaccaactgcaaa
catcactatggtgtcgagaaagccgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaagg
ggagatttcctctcggaggagtggagggagcggattgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaatcgtgtcctcaaagcccttcgcacctctcaacttcaggataaac
agtcgaaacttgagtgacattggtaccatcatgcgtgtggtggagctctcgccgctgaag
ggctcagtgtcatggacggggaagccagtctcctactacctgcataccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaacccaaaactcagggaggaacaggaggca
gctcggcgccggcagcagcgagaaaataagagcaacacgaccaccccgaccaaggtgccc
gagagcaaggcggccgttcccgcagacacccccgtggactctggtgctgaggaagagaaa
gctggggcgaccaccatcaagaagccatctccctccaaagcccggaagaagaagctgaac
aagaagggccggaagatggccggccggaagcgcgggcgccccaagaagatgagctccacg
aaccccgagcgcaagcccaagaagacccagagcgcactggacctgctgcatgcccagacc
gtgtcgcgggcggcatcaccctcgccgcaggatgcgcacaggccacctcacagcccattc
taccagctacctcccagcgtgcagcggcacccccctgagcagctgctgctggcacctacc
ccgcccgcactgcagaagctgctagaatccttcaagattcagtacttacagttcctggcg
tacacaaagactcctcagtacaaagccaacctgcagcagctgctggaccaggagaaggag
aagaacgcccggttgctgggcgccgcacagcaactgttcggccactgccaagctcagaaa
gaggagatcaagaggctcttccagcagaaactggacgagctgggcgtgaaggcgctgacc
tacaatgacctgatccaagcacagaaggagatctcggctcataaccagcagctgcgggag
cagacagagcagctggagaagggcaacagggagctgcgaagccggagcctgcagctgctc
aaggctcgctgcgaggaactgaagttggactggtccacactgtccctagagaacctgctg
aaagagaagcaggccctgaagagccagatctcggagaagcagaggcactgcctggagttg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcagctcaag
tcctgtgtgccacccgatgacaccctgtctgcgcacctgcgggggaggggtggcctggcc
cgggagccagaggctgagcctggccggctgcgcctggagctggactgtgccaagttctcc
ctgccccacttcagcagcacaagcccggaactctccatgaatggccatgcggccagctac
gagctctgcagcgcgctcagccgaccctcgcccaagcagaacactccccagtacctgacc
tcccccctggaccaggaggtcgtgccctgcacccccagccatggcggccggccaaggctc
gagaagttgtctggcctggccctgcctgactacactaggctctcccctgccaagctggtg
ctgaggcgtcacctgagccaggatcacgtggctggcaacaaggcagccaccagcgatctg
cacccacgagtggagcccaccaaggagaatggcctcccataccacagccccggcatcacc
aacggcatcaagctgagcccccaagatcctcggccctcgtcccccacaggcttacagatg
acgggagagaagggcagcgagaagggtgtgagggagcgcgcctacgccagcagtggggag
gccatcaccagcctgcctgtcagcatcccgctcagcaccgtgcagcccagcaagctgcct
gtcagcatccctctggccagcgtggtgctgcccagccgcgctgaaaaagtgagaagcacc
cccagcccaggcccacaggcccgagagacctccaccactcttgagaagcagatgggtgct
aatgcccatggcgccgggggcagtgctgccgggggcaaaggtcttgccctgcctcccaca
ggcttcacctacgctggctcaatggccatcagtgggaccctggctggcagcccggtgcca
cttgcccctggagctgagccccccgccttggatgagtcctccagctccggaagtctcttt
gccaccatggggtcccgcagctccaccccgcagcacccgcccctgctgacacagcctcgc
agttgtggctctgcctcacccgcccctcagctctgcaccagcccccggctggccacccag
ggcccgctccctgacgccagcaaaggggacctccccgctgaggctggcttctcagaccca
gagagcgaagccaagaggagggtcgtgttcaccatcgcagccggtgctggcagtgccaag
cagtcgccatccagcaagcacagccccctgccatcgggcactcgcggggacagtggccag
agccatggacaggacagccgcaagcggggcagaagaaagcgggcatcggcagggaccccc
agcctgagctcgggcgtgtcccccaagcgccgggccctaccatctgtcgctggcctcttc
actcagtcttcagggtcccccctgaatctcaactccatggttaacaacatcaaccagcct
ttggagatcacggccatctcatcccctgagagctctctgaagagttcccctgtcccctac
caggacaatgaccagccccccgtgctcaagaaggaaaagcccctgagccagaccaacggg
gcccactactccccactgacctcggacgaggagcagggctcggaggatgagcccggcagt
gccagaatcgagagaaaaattgcaacaatctccttagaaagcaaatctcctccgaaaacc
ttggaaaatggtggcggcctggcgggaaggaaggtgccgccggccagcgagccagtcaac
agcagcaagtggaagtccacgttctcgcccatctccgaccttggcctgtccagggcggct
gatagcccgttgcaggccagctccactctgagccacagctccctgtttgctttccggccc
agcctggaggagcccagctcagccgacaccaagctggccgcccactccaggaagagcttc
tcgggcaccctgccagcggcaggcgggttgagtcccagcagccaccctgccagcggcttt
gcccttggcgggggcctggcaaccgacctcagtttacacagcttcagtgatggtgcttct
ctctcccacaaggcccccgaggcggctggcttgggtgcgcccttgagcttccctgcccca
cggggcaaggagggcggcgcctcagaacctggccccttctcgaacaagaggcagctggat
ggactgggcccaaagggcgaggggggcctgcccacctgcgggcccacggacaaggcctct
ctggtgcacagcaaggcgggcaagggccgtgaccgtgagcccgacgtgaagaatggccac
aacctcttcatggccgccgccaccgcaccccctgggggcctcctcagtggcccaggcctc
accccggcagtgtcctcagcaggcagcacggccccggccacccagacacaccggcccttc
ctgggcgcctttgcccccagcccgcagttcacactgggccccatgtccctgcaggccaac
ctgggcccatccgtgctgcagtccctgttcagttccgtgcccgccgccggcctggtgcat
ggctcgtccgccgccaccagactgaccaactcgcacgccatgggcagcttctcctccggg
gtcgctggcggcgcagttggaggtgtctttaaccacgcggtgcctcccgcctccgctcat
ccgtttggagccagtttcggcagtggggctgcatgtcgcagcgccacgctgagcttaacc
ccgctgcaggcggtggccagcaccccggcctcttcctttcaggccccgtcctctgcggag
ccgaggccgcccccaccccctccccacctgggccggccccctccagggcagcccgccctt
cacgcaccgcccccccctaacgctgccttgcctcctccccccgcgctgctcccggctaac
tctgagcccgtgcttctgcagaaccttgcgtccctcccggctaaccaagctttcttacct
gcctcctctgccgcctctctgccgcctgctaacgcctctgtgtccatcaagctggcctcc
ctcccgcacaaggtgtcccgcccctccttcacggtgcaccaccagcccctgcctgggctg
gccctggcccaggccacacccatgatcccgcaggccagctccacggggccgcccgccgtg
tgggtttcccttggcatgccgcctccatatgccgcgcgccttgcgggggttaagccgcga
taa
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integrated database retrieval system
