Sus scrofa (pig): 396917
Help
Entry
396917 CDS
T01009
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
396917 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ssc03032
]
396917 (TOP2A)
03036 Chromosome and associated proteins [BR:
ssc03036
]
396917 (TOP2A)
Enzymes [BR:
ssc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
396917 (TOP2A)
DNA replication proteins [BR:
ssc03032
]
Eukaryotic type
DNA Topoisomerases
396917 (TOP2A)
Chromosome and associated proteins [BR:
ssc03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
396917 (TOP2A)
Centrosome formation proteins
Centriole proteins
396917 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
396917
NCBI-ProteinID:
NP_999049
Ensembl:
ENSSSCG00000017473
UniProt:
O46374
A0A480JS00
LinkDB
All DBs
Position
12:22001300..22028452
Genome browser
AA seq
1533 aa
AA seq
DB search
MEVSPLQPVNENMQVNKTKKNEEAKKRLSIERIYQKKTQLEHILLRPDTYIGSVESVTQQ
MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFHPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDLYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVAKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRLLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKEADKSDSVADSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQIGLPGKGGKA
KGKKTQMAEVLPSPCGKRVIPRVTVEMKAEAEKKIKKKIKSENTEGSPQEDGMEVEGLKQ
RLEKKQKREPGTKTKKQTTLPFKPIKKAKKRNPWSDSESDISSDESNFNVPPREKEPRRA
AAKTKFTVDLDSDEDFSDADEKTRDEDFVPSDTSPQKAETSPKHTNKEPKPQKSTPSVSD
FDADDAKDNVPPSPSSPVADFPAVTETIKPVSKKNVTVKKTAAKSQSSTSTTGAKKRAAP
KGAKKDPDLDSDVSKKPNPPKPKGRRKRKPSTSDDSDSNFEKMISKAVTSKKPKGESDDF
HLDLDLAVASRAKSGRTKKPIKYLEESDEDDLF
NT seq
4602 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcgccacttcagcctgtaaatgaaaatatgcaagtcaacaaaacaaagaaa
aatgaagaggctaagaaaagattgtctatagaaagaatctatcaaaagaaaacacagttg
gaacacattttgctccgcccagacacctacattggctctgtggaatcagtgacccagcaa
atgtgggtttatgatgaagacattggcattaactatagggaagtcacttttgttcctggt
ttgtacaaaatcttcgatgagattctagtcaatgctgcagacaacaagcaaagagacccc
aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaat
aatggaaaaggaattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagtaactatgatgatgaagaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaactgtgtaacatattcagtaccaaatttactgtggaa
acagccagtagagaatataagaaaatgttcaaacagacgtggatggataacatggggaga
gctggtgagatggaactgaagccctttaatggagaagattatacgtgtattaccttccac
cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcacttatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaggtctttctgaatggaaat
aagcttccagtaaaaggattccgtagctatgtagatttgtatttgaaggataaggttgat
gaaactggcaatccattgaaaattatccatgaacaagtaaaccacagatgggaagtgtgt
ttaacaatgagtgaaaagggctttcagcaaattagctttgtcaacagcattgctacctcc
aagggtggcagacatgttgattatgtagctgatcagattgtggctaaacttgttgatgtt
gtaaagaagaaaaacaagggcggtgttgcagtaaaagcacatcaggttaagaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgactcccagacaaaggagaat
atgactttacaagtcaagagctttggatcaacatgccaactgagtgaaaaattcatcaaa
gctgcaattggctgtggtattgtagaaagcatcctaaactgggtgaaatttaaggcccaa
gtccagttaaacaagaaatgttcagctgtaaaacataacagaatcaaaggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaattccactgagtgtacgcttatcctgaca
gagggagactcagccaaaactttggcagtttcaggccttggtgtggttgggagagacaaa
tacggagttttccctcttaggggaaaaatactcaatgttcgagaagcttctcataaacag
ataatggaaaatgctgaaattaacaacataatcaagattgtgggtcttcaatacaagaaa
aactatgaagatgaagattcattgaagactctacgttatgggaagataatgattatgaca
gatcaggaccaagacggttcccatatcaaaggcttgctgattaactttatccatcataac
tggccctctcttctgcgacatcgtttcctggaggaatttatcactcccattgtaaaggta
tctaaaaacaagcaagaaatggctttctatagccttcctgaatttgaagaatggaagagt
tctacaccaaatcataaaaaatggaaagtcaaatactacaaaggtttgggtaccagcaca
tcaaaagaagctaaagaatactttgcagatatgaaaagacatcgtatccaattcaaatat
tccggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaacgcatttcatggaagatagacggcaacgaaagttacttggcctt
cctgaggattacttgtatgggcaaactaccacatatctgacatacaatgacttcataaac
aaggaacttatcctgttctcaaattctgataatgagagatctatcccatccatggtggat
ggtttgaaaccgggacagagaaaagttttgtttacatgtttcaaacgaaatgacaagcga
gaagtgaaggtggcccagttagctgggtcagtagctgagatgtcctcttatcatcatggt
gagatgtcacttatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttacagcccattggtcagtttggtaccaggttgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagtcctttggctcggttgttatttccacca
aaagatgatcacacattgaagtttttatatgatgacaaccaacgtgttgaacctgaatgg
tacattcctattatacccatggtgctgataaatggcgctgaaggaattggtactgggtgg
tcctgcaaaatccccaactttgatgttcgtgaagttgtgaacaacatcagactgttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaaaggtactatcgaa
gagctggctccaaatcagtatgtgattagtggtgaagtggctattcttaattccacaact
attgaaatctccgagcttcccatcagaacatggacccagacgtataaggagcaggttcta
gagcccatgttgaatggcactgagaagacaccccctctcataacagattatagggagtac
cacacagacaccactgtgaagtttgttgtgaagatgactgaagaaaaactggcagaggca
gagagagtcggactacacaaagtcttcaagctgcaaaccagtctcacatgcaactctatg
gtgctttttgatcatgtaggctgtttaaagaaatacgacacagtgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctgggaatg
cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagaaaaaatagat
ggcaaaataatcattgaaaacaagcctaagaaagaattaattaaagttctgattcagagg
ggatatgactcggatcctgtgaaggcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagaaagtgacaatgaaaaggaagctgacaagagtgactctgtagcagat
tctggaccaaccttcaactaccttcttgatatgcctctttggtatctaaccaaggaaaag
aaagatgaactgtgcaaactaagaaatgaaaaagagcaagaactagaaacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttattgaagagctggaggct
gttgaagcaaaggaaaaacaagatgaacaaataggacttcctgggaaagggggaaaagca
aaggggaaaaaaacacaaatggcagaagttttgccttctccatgtggaaaaagagtcatc
ccccgagtgactgtagagatgaaagcagaggcagagaagaaaatcaaaaagaaaatcaag
agtgaaaatactgaaggaagccctcaagaggatgggatggaagtagagggtctaaaacag
agactggagaagaaacagaaaagagaaccaggtaccaagacaaagaaacaaactactttg
ccatttaaaccaattaagaaagcaaagaagagaaacccctggtctgattcagaatcagat
ataagcagtgatgaaagtaatttcaatgtccctccacgagaaaaagagccacggagagca
gcagcgaaaaccaaattcacagtggacttggattcagatgaagatttctcagatgctgat
gaaaaaactcgagatgaagattttgttccatcagatactagtccacaaaaggccgaaact
tcccctaaacatactaacaaagaaccgaagccacagaaaagtaccccatcagtctcagac
tttgacgctgacgatgccaaggataatgtaccgccttctccaagctctccagttgctgat
ttcccagctgtaactgaaactataaaacctgtttctaagaagaacgtgacagtgaagaag
acagcagcaaaaagtcagtcttccacctctactacaggcgccaaaaaaagggctgcaccg
aaaggagccaaaaaggatccagacttggattctgatgtctctaaaaagcctaatcccccc
aaacctaagggtcgccgcaaaaggaagccatccacttctgatgattccgactctaatttc
gagaaaatgatttctaaagcagtcacaagcaagaaacccaagggggagagcgatgacttc
catctggacttagacttggctgtggcttctcgggcaaaatctggacggaccaagaagcca
attaagtaccttgaagaatcagatgaagatgatctgttttaa
DBGET
integrated database retrieval system
