KEGG   Sus scrofa (pig): 397027
Entry
397027            CDS       T01009                                 
Symbol
CAPN1
Name
(RefSeq) calpain-1 catalytic subunit
  KO
K01367  calpain-1 [EC:3.4.22.52]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04141  Protein processing in endoplasmic reticulum
ssc04210  Apoptosis
ssc04217  Necroptosis
ssc04218  Cellular senescence
ssc04382  Cornified envelope formation
ssc05010  Alzheimer disease
ssc05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    397027 (CAPN1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    397027 (CAPN1)
   04217 Necroptosis
    397027 (CAPN1)
   04218 Cellular senescence
    397027 (CAPN1)
 09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    397027 (CAPN1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    397027 (CAPN1)
   05022 Pathways of neurodegeneration - multiple diseases
    397027 (CAPN1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ssc01002]
    397027 (CAPN1)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.52  calpain-1
     397027 (CAPN1)
Peptidases and inhibitors [BR:ssc01002]
 Cysteine peptidases
  Family C2: calpain family
   397027 (CAPN1)
SSDB
Motif
Pfam: Peptidase_C2 Calpain_III EF-hand_6 EF-hand_1 EF-hand_8 EF-hand_7 CAPN13-like_C_EFh
Other DBs
NCBI-GeneID: 397027
NCBI-ProteinID: NP_001335713
Ensembl: ENSSSCG00000012999
UniProt: P35750
LinkDB
Position
2:complement(6997513..7024410)
AA seq 714 aa
MAEEVITPVYCTGVSAQVQKLRAKELGLGRHENAIKYLGQDYEQLRAHCLQSGSLFRDEA
FPPVPQSLGFKELGPNSSKTYGVKWKRPTELFSNPQFIVDGATRTDICQGALGDCWLLAA
IASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHS
AQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYSIILK
ALERGSLLGCSIDISSVLDMEAVTFKKLVKGHAYSVTGAKQVNYQGQMVNLIRMRNPWGE
VEWTGAWSDGSSEWNGVDPYQRDQLRVRMEDGEFWMSFRDFLREFTRLEICNLTPDALKS
QRVRNWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEETDDPEDDYGGRESGCSF
VLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPVHLKRDFFLANASRARSEQFINL
REVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKKAGTQELDDQVQAILPDEQVLSE
EEIDENFKALFRQLAGEDMEISVRELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRD
GNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLFELII
TRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA
NT seq 2145 nt   +upstreamnt  +downstreamnt
atggccgaggaggtcatcactccggtgtactgcactggggtgtctgcacaagtgcagaag
ctgcgggccaaggagctgggcctgggccgccatgaaaatgccatcaagtacctgggccag
gattacgagcagctccgggctcactgcctgcagagtgggagcctcttccgtgatgaggct
ttccctccagtgccgcagagcctgggcttcaaggaactgggccccaactcctccaaaacc
tatggcgtcaagtggaagcgtcccacggagctgttctcaaacccccagttcatcgtggat
ggagccacccgaacagacatctgccagggagcactgggggactgctggctcctggctgcc
atcgcctcccttaccctcaacgacaccctcctgcaccgagtagttccacacggccaaagc
ttccagaatggctatgctggcatcttccatttccagctgtggcagtttggggagtgggtg
gacgtggtggtggatgacctgctgcccaccaaagacgggaagctggtgttcgtgcactct
gcccaaggcaacgagttctggagcgccctgctcgagaaggcttatgccaaggtgaatggc
agctacgaggccctgtccgggggcagcacctccgagggctttgaggacttcacgggcggg
gtcaccgagtggtacgagctgcggaaggcacccagcgacctctacagcatcatcctcaag
gcgctggagcgaggctccctgctgggctgctccattgacatctccagcgttctggacatg
gaggctgtcaccttcaagaagctagtgaagggccacgcctactccgtgactggggccaag
caggtgaactaccagggccagatggtgaacctgatccggatgcggaacccctggggcgag
gtggagtggacgggagcctggagtgatggctcctcggagtggaacggtgtggacccctac
cagcgggatcagctccgggtccggatggaggatggggagttctggatgtccttccgagac
ttcttgcgtgagttcacccgcctggagatctgcaacctgacgcccgacgcgctcaagagc
cagagggtccgcaactggaacaccaccctctacgagggcacctggcggcgggggagcacc
gcggggggctgccgcaactacccagccaccttctgggtgaacccccagttcaagatccgg
ctggaggagacggatgacccagaggacgactacgggggccgtgagtcaggctgcagcttc
gtgctcgccctcatgcagaaacaccgccgccgggagcgccgattcggccgggacatggag
accatcggctttgccgtctatgaggtccctccggagctggtgggccagccggtgcacctg
aagcgggacttcttcctggccaacgcctctcgggcccggtccgagcagttcatcaacctg
cgggaggtcagtacccgcttccgcctgccgcccggcgagtacgtggtggtgccttccacc
ttcgagcccaacaaggagggcgactttgtgctgcgtttcttctcagagaagaaagccggg
acccaagagctggacgaccaggtccaggccattctccccgacgagcaagtgctctcggaa
gaggagattgatgagaacttcaaagcgctcttcagacagctggcaggggaggacatggag
atcagcgtcagggagctgcgcaccatcctcaacaggatcatcagcaaacacaaagacctg
cggaccaagggcttcagcctggagtcctgccgcagcatggtcaacctcatggaccgtgat
ggcaacgggaagctgggcctggtggagttcaacatcctgtggaaccgcatccggaattac
ctgtccatcttccggaagttcgacttggacaagtcaggcagcatgagcgcctacgagatg
cggatggccatcgagtctgcagggttcaagctcaacaagaagctgtttgagctcatcatc
acccgctactcggagcccgacctggccgtggacttcgacaacttcgtgtgctgcctggtg
cggctggagaccatgttccgatttttcaagactctggacacagatctggatggagttgtg
acctttgacttgtttaagtggttgcagctgaccatgtttgcatga

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