Sus scrofa (pig): 397201 Help Entry 397201            CDS       T01009                                  Symbol JAK2 Name (RefSeq) tyrosine-protein kinase JAK2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism ssc  Sus scrofa (pig) Pathway ssc01521   EGFR tyrosine kinase inhibitor resistance ssc04062   Chemokine signaling pathway ssc04081   Hormone signaling ssc04148   Efferocytosis ssc04151   PI3K-Akt signaling pathway ssc04217   Necroptosis ssc04550   Signaling pathways regulating pluripotency of stem cells ssc04630   JAK-STAT signaling pathway ssc04658   Th1 and Th2 cell differentiation ssc04659   Th17 cell differentiation ssc04725   Cholinergic synapse ssc04917   Prolactin signaling pathway ssc04920   Adipocytokine signaling pathway ssc04933   AGE-RAGE signaling pathway in diabetic complications ssc04935   Growth hormone synthesis, secretion and action ssc05140   Leishmaniasis ssc05145   Toxoplasmosis ssc05152   Tuberculosis ssc05161   Hepatitis B ssc05164   Influenza A ssc05167   Kaposi sarcoma-associated herpesvirus infection ssc05168   Herpes simplex virus 1 infection ssc05200   Pathways in cancer ssc05207   Chemical carcinogenesis - receptor activation ssc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ssc05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ssc00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     397201 (JAK2)    04151 PI3K-Akt signaling pathway     397201 (JAK2)   09133 Signaling molecules and interaction    04081 Hormone signaling     397201 (JAK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     397201 (JAK2)   09143 Cell growth and death    04217 Necroptosis     397201 (JAK2)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     397201 (JAK2)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     397201 (JAK2)    04659 Th17 cell differentiation     397201 (JAK2)    04062 Chemokine signaling pathway     397201 (JAK2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     397201 (JAK2)    04917 Prolactin signaling pathway     397201 (JAK2)    04935 Growth hormone synthesis, secretion and action     397201 (JAK2)   09156 Nervous system    04725 Cholinergic synapse     397201 (JAK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     397201 (JAK2)    05207 Chemical carcinogenesis - receptor activation     397201 (JAK2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     397201 (JAK2)   09172 Infectious disease: viral    05161 Hepatitis B     397201 (JAK2)    05164 Influenza A     397201 (JAK2)    05168 Herpes simplex virus 1 infection     397201 (JAK2)    05167 Kaposi sarcoma-associated herpesvirus infection     397201 (JAK2)   09171 Infectious disease: bacterial    05152 Tuberculosis     397201 (JAK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     397201 (JAK2)    05140 Leishmaniasis     397201 (JAK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     397201 (JAK2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     397201 (JAK2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     397201 (JAK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ssc01001]     397201 (JAK2) Enzymes [BR:ssc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      397201 (JAK2) Protein kinases [BR:ssc01001]  Non-receptor tyrosine kinases   JAK family [OT]    397201 (JAK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 SH2_1 Jak1_Phl SH2 ABC1 FERM_C_FAK1 RIO1 Kinase-like Motif Other DBs NCBI-GeneID:  397201 NCBI-ProteinID:  NP_999278 Ensembl:  ENSSSCG00000005215 Vega:  OTTSUSG00000002988 UniProt:  O19064 LinkDB All DBs Position 1:complement(216849744..217002310) Genome browser AA seq 1131 aa AA seqDB search MGMACLTMTEMEGTSTSPVHQNGDIPGNANSVKQIDPVLQVYLYHSLGKAEGDYLKFPAG EYVAEEICVAASKACGITPVYHSMFALMNETERIWYPPNHVFHVDESTRHNVLYRIRFYF PYWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLYGWVKIPVTHETQEECLG MAVLDMMRIAKEKDQTPLDIYSSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR GKHKESETLTEQDLQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKSLEIELSSLR EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKAGNQT GLFVLRCSPKDFNKYFLTFAVERENVTEYKHCLITKNENGEYNLSGTRKNFSNLKDLLNC YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKI RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA MHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDRHQLPAPKWTEL ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE LLKNNGRLPRPDGCPDEIYIIMTECWNNNVNQRPSFRDLALRVDQIRDSMA NT seq 3396 nt NT seq  +upstreamnt  +downstreamnt atgggaatggcttgcctcacaatgacggaaatggaaggaacatccacatctcctgtacat cagaatggtgatattcctggaaatgctaattctgtgaagcaaatagatccagtcctacag gtctatctttatcactcccttgggaaagctgagggggattatttgaagtttccagctgga gagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtg tatcatagtatgtttgctttaatgaatgaaacagaaaggatctggtatccacccaaccat gtcttccatgtagatgaatctaccaggcacaatgtactctacagaatcagattttacttt ccttactggtactgtaatggcagcaacagaacctatcggcatggaatatctcgaggtgct gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcgacatgat tttttgtatggatgggtaaagatacctgtgactcatgaaactcaggaagaatgtcttggg atggcagtgttagatatgatgagaatagccaaagaaaaggatcaaaccccactggacatc tatagttctgtcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagac tatcatattttgacaaggaagcgaataaggtacagatttcgcagatttattgagcaattc agccattgcaaagccactgccagaaacttgaaacttaaatatcttataaatctggaaact cttcagtctgccttctacacagaacagtttgaagtaaaagaacctggaagaggtccttca ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga gggaaacataaagaaagtgagacactgacagaacaggatttacaattatattgtgatttt cctgatatcattgatgtcagtattaaacaggcaaaccaagaaggctcaaatgaaagcaga attgtaactattcataagcaagatggcaaaagtctggaaattgaacttagctcattaaga gaagctttgtcttttgtatcgttaattgatggatattatagattaactgcagatgcacat cattacctttgtaaagaagtagcacctccaatggtgcttgaaaatatacaaagcaactgt catggcccaatttcaatggattttgccatcagtaaactgaagaaagcaggtaatcagact ggactctttgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct gttgagcgagaaaatgtcactgaatataagcactgtttgattacaaaaaatgagaatggc gaatacaacctcagtggtactaggaagaacttcagtaaccttaaagatcttttgaattgt taccaaatggaaactgttcgttcagacagtataattttccagtttactaaatgctgtccc ccaaagccaaaagataagtcaaaccttctagtctttagaaccaatggtatttctgatgtg ccaacctcaccaacattacagaggcataataatgtgaaccaaatggtgtttcacaaaatc agaaatgaagatttgatatttaatgaaagtcttggccaaggcacgtttacaaaaattttt aaaggtgtaagaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta aaagttttggataaagcacatagaaactactcagagtctttctttgaagcagcaagcatg atgagccagctttctcataaacatctggttttaaattatggagtatgtgtctgtggagag gagaatattctggttcaggagtttgtaaaatttgggtcactggatacatatctgaaaaag aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc atgcattttctagaagagaaaacccttattcatgggaatgtgtgcgccaaaaatattctt cttatcagagaagaagacaggaagacaggaaatcctcccttcatcaaacttagtgatcct ggcatcagtattacagttttgcccaaggacattctgcaggagagaataccatgggtgcct cctgaatgcattgaaaatcctaaaaatctaaacttggcaacagataaatggagttttggt accactttgtgggaaatctgcagtggaggtgataagcctctgaatgctttggattctcaa agaaagctacagttttatgaagataggcatcagcttcctgcaccaaagtggacagaatta gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc atcatacgagaccttaatagcttgtttactccagattatgaactactaacagaaaatgat atgttaccaaatatgagaataggtgccctagggttttctggtgcatttgaagaccgagac cctacacagtttgaagagagacacttgaaatttctacagcaactgggcaagggtaatttt gggagtgtggagatgtgccggtatgaccctctacaagacaacactggggaggtggtggct gtgaaaaagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaa atccttaaatccttgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct ggtcggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagattat cttcaaaaacataaagaacggatagatcataaaaaacttcttcagtatacatctcagata tgcaagggtatggagtatcttggtacaaagagatatatccacagggatctggcaacaagg aatatattggtggagaatgaaaacagagttaaaataggagattttgggttaaccaaagtc ttgccacaagacaaagaatattacaaagtgaaagaacctggtgaaagtcccatattttgg tatgcaccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagcttt ggagtggttctgtatgaacttttcacatatatcgagaagagtaaaagcccaccagcggaa tttatgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcacttgatagaa cttctgaagaataatggaagattaccacggccagatggatgcccagatgagatttatata atcatgacagaatgctggaacaataatgtaaatcaacgcccctctttcagagacctagct cttcgagttgatcaaataagggacagtatggcttga

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