Sus scrofa (pig): 397202 Help Entry 397202            CDS       T01009                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism ssc  Sus scrofa (pig) Pathway ssc01521   EGFR tyrosine kinase inhibitor resistance ssc04151   PI3K-Akt signaling pathway ssc04217   Necroptosis ssc04380   Osteoclast differentiation ssc04550   Signaling pathways regulating pluripotency of stem cells ssc04620   Toll-like receptor signaling pathway ssc04621   NOD-like receptor signaling pathway ssc04630   JAK-STAT signaling pathway ssc04658   Th1 and Th2 cell differentiation ssc04659   Th17 cell differentiation ssc05140   Leishmaniasis ssc05145   Toxoplasmosis ssc05152   Tuberculosis ssc05160   Hepatitis C ssc05161   Hepatitis B ssc05162   Measles ssc05163   Human cytomegalovirus infection ssc05164   Influenza A ssc05165   Human papillomavirus infection ssc05166   Human T-cell leukemia virus 1 infection ssc05167   Kaposi sarcoma-associated herpesvirus infection ssc05168   Herpes simplex virus 1 infection ssc05169   Epstein-Barr virus infection ssc05171   Coronavirus disease - COVID-19 ssc05200   Pathways in cancer ssc05203   Viral carcinogenesis ssc05212   Pancreatic cancer ssc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:ssc00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     397202 (JAK1)    04151 PI3K-Akt signaling pathway     397202 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     397202 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     397202 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     397202 (JAK1)    04621 NOD-like receptor signaling pathway     397202 (JAK1)    04658 Th1 and Th2 cell differentiation     397202 (JAK1)    04659 Th17 cell differentiation     397202 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     397202 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     397202 (JAK1)    05203 Viral carcinogenesis     397202 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     397202 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     397202 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     397202 (JAK1)    05161 Hepatitis B     397202 (JAK1)    05160 Hepatitis C     397202 (JAK1)    05171 Coronavirus disease - COVID-19     397202 (JAK1)    05164 Influenza A     397202 (JAK1)    05162 Measles     397202 (JAK1)    05168 Herpes simplex virus 1 infection     397202 (JAK1)    05163 Human cytomegalovirus infection     397202 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     397202 (JAK1)    05169 Epstein-Barr virus infection     397202 (JAK1)    05165 Human papillomavirus infection     397202 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     397202 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     397202 (JAK1)    05140 Leishmaniasis     397202 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     397202 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ssc01001]     397202 (JAK1) Enzymes [BR:ssc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      397202 (JAK1) Protein kinases [BR:ssc01001]  Non-receptor tyrosine kinases   JAK family [OT]    397202 (JAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  397202 NCBI-ProteinID:  NP_999279 Ensembl:  ENSSSCG00000003809 Vega:  OTTSUSG00000002956 UniProt:  F1S818 Q9TTJ1 LinkDB All DBs Position 6:147320288..147567188 Genome browser AA seq 1141 aa AA seqDB search MAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEVCIKAAQECCISP LCHNLFALYDESTKLWYAPNRTITVDDKTSVRLHYRMRFYFTNWHGTNDNEQSVWRHSPK KQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQDGHDIENECLGM AVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFN NKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMSRFHPNDGGNVLY EVMVTGNLGIQWRQKPNVVPIEKEKNKLKRKKLESKHKKDEEKNKIREEWNNFSYFPEIT HIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLIDGYFRLTADAHHYLCTDVAPPLIV HNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEVLGGQKQ FKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLKRCCQPKPREISNL LVATKKAQEWQPVYTMSQLSFDRILKNDIMQGEHLGRGTRTHIYSGTLMDYKDDEGTSEE KRKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGG PLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGP FIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTTLWEICYNGEIP LKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNP DIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPE SGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKN KINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKE YYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIG PTHGQMTVTRLVNTLKEGKRLPCPPNCPEEVYQLMRKCWEFQPSNRTTFQNLIEGFEALL K NT seq 3426 nt NT seq  +upstreamnt  +downstreamnt atggctttttgtgctaaaatgaggagctccaagaagaccgaggtgaatctggaggcccct gagccgggggtggaagtgctcttctatctgtcggatagggagcccctccggctgggcggc ggggagtacacggccgaggaggtgtgcatcaaggcggcgcaggaatgctgtatctctcct ctgtgtcacaacctctttgccctgtatgatgagagcaccaagctctggtacgctccaaat cgcaccatcaccgtcgatgacaagacgtcagttcggctccactaccggatgaggttctat ttcaccaactggcatgggaccaatgataatgagcagtcggtatggcggcattctccaaag aaacagaaaaatggctacgagaaaaaaaaagttccagatgcaacccctctccttgatgcc agctcattggaatatctctttgctcaggggcagtacgatttggtcaaatgcctggctccc attcgagaccccaagacggagcaggacgggcatgatattgagaacgagtgtctgggcatg gctgtgttggccatctcccactatgccatgatgaagaagatgcagttgccagaacttccc aaggacatcagctacaagcgatatattccagaaacattgaataagtccatcagacagagg aatcttcttacgaggatgcggataaataatgttttcaaggatttcctaaaggagtttaac aacaagaccatttgtgacagtagcgtgtctacgcatgacctgaaggtgaaatacctggct accttggaaactttgaccaaacattatggtgctgaaatatttgagacgtctatgttactg atttcatcggaaaatgagatgagtcggtttcatccaaatgacggtggaaatgttctctat gaggtgatggtgactggaaatctcgggatccagtggaggcagaaacccaatgttgttccc attgaaaaggaaaaaaataaactgaaacgaaaaaaactggaaagtaaacacaagaaggat gaggaaaaaaacaaaatccgggaagagtggaacaatttttcgtacttccctgagatcact cacattgtcatcaaggagtctgtggtcagcattaacaagcaggacaacaaaaaaatggaa ctgaagctctcttcccacgaggaggccttgtccttcgtgtccctgatagacggctacttc cggctcacagcagatgcccatcattacctctgcaccgacgtggctcccccgttgattgtc cacaacatacagaatggttgtcacggtccaatctgcacagagtacgccatcaataaactg cggcaagagggcagcgaggaggggatgtacgtgctgcggtggagctgcactgactttgac aacatcctcatgaccgtcacctgctttgagaagtccgaggtgctaggtggccagaagcag ttcaagaacttccagattgaggtgcagaagggccgctacagcctgcatggctcggaccgc agctttcccagcctcggggacctcatgagccacctgaagaagcagatcctgcgcacggac aacatcagcttcgtgctgaagcgctgctgccagcccaagccccgagaaatctccaatttg ctggtggccaccaagaaagcccaggagtggcagcccgtctacaccatgagccagctgagt ttcgatcggatccttaagaatgacattatgcaaggcgagcaccttgggagaggcactcgg acgcacatctactccggcaccctcatggactacaaggacgacgaagggacttccgaagag aagagaaaaataaaagtgatcctcaaagtcttagaccccagccacagggacatctctctg gccttcttcgaggcagccagcatgatgaggcaggtctcccataagcacatcgtgtacctc tacggcgtctgtgtccgggacgtggagaacatcatggtggaggagtttgtggagggggga cccctggatctcttcatgcaccggaaaagcgacgtcctcaccacaccctggaagttcaaa gttgccaaacagctggccagtgccctgagttacctggaggataaagacctggtccatgga aatgtgtgcactaaaaacctcctcctggcccgtgagggcatcgacagcgagtgcggcccg ttcatcaagctcagtgaccccggcatccccatcacggtgctgtccaggcaagagtgcata gaacgaatcccgtggatcgctcccgaatgtgttgaggactccaagaacctgagtgtggct gcggacaaatggagctttggaaccacgctctgggagatctgctacaatggcgagatcccc ttgaaagacaagacactcattgagaaagagagattctatgaaagccgatgtaggccggtg accccatcttgtaaggagctggctgaccttatgacccgctgcatgaactacgaccccaac cagagacccttcttccgagccatcatgagagacatcaataagctggaggaacagaatcca gacattgtatcagaaaaaaagccagcaactgaggtggatcccacacattttgaaaagcgg ttcttaaagaggatccgtgacctgggagagggccactttgggaaggtcgagctttgtagg tatgaccccgagggggacaacacaggggagcaggtggctgtcaagtccctgaagcctgag agcggaggaaaccacatagctgatctgaagaaggagattgaaatcttgagaaacctttat cacgagaacattgtcaagtataaaggcatttgcacagaggacggaggaaatggtattaag cttatcatggaattcctgccttcgggaagccttaaggagtatcttccaaagaataaaaac aaaatcaacctcaaacagcagttaaaatacgccgttcagatttgtaaggggatggactat ttgggttctcggcaatacgttcaccgggacttggcagcaagaaatgttcttgtcgagagt gaacaccaagtgaaaattggagacttcggtctcaccaaagccatcgaaaccgataaggag tactacacagtcaaggacgatcgggacagccctgtgttttggtatgctccggagtgttta attcagtgtaaattttacatcgcctccgatgtctggtctttcggggtgactctgcatgag ctgctcacttactgtgattcggattccagtcccatggcgttgttcctgaaaatgataggc ccaactcatggccagatgacggtaacaagacttgtgaatacattaaaagaaggaaaacgt ttgccttgtccacctaactgtccagaagaggtttatcaactgatgagaaaatgctgggaa ttccaaccatctaatcggacaacctttcagaaccttattgaaggatttgaagcactttta aaataa

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