Sus scrofa (pig): 397363
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Entry
397363 CDS
T01009
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc04217
Necroptosis
ssc04380
Osteoclast differentiation
ssc04620
Toll-like receptor signaling pathway
ssc04621
NOD-like receptor signaling pathway
ssc04630
JAK-STAT signaling pathway
ssc04658
Th1 and Th2 cell differentiation
ssc04659
Th17 cell differentiation
ssc05145
Toxoplasmosis
ssc05160
Hepatitis C
ssc05161
Hepatitis B
ssc05162
Measles
ssc05164
Influenza A
ssc05165
Human papillomavirus infection
ssc05167
Kaposi sarcoma-associated herpesvirus infection
ssc05168
Herpes simplex virus 1 infection
ssc05169
Epstein-Barr virus infection
ssc05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
397363 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
397363 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
397363 (TYK2)
04621 NOD-like receptor signaling pathway
397363 (TYK2)
04658 Th1 and Th2 cell differentiation
397363 (TYK2)
04659 Th17 cell differentiation
397363 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
397363 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
397363 (TYK2)
05160 Hepatitis C
397363 (TYK2)
05171 Coronavirus disease - COVID-19
397363 (TYK2)
05164 Influenza A
397363 (TYK2)
05162 Measles
397363 (TYK2)
05168 Herpes simplex virus 1 infection
397363 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
397363 (TYK2)
05169 Epstein-Barr virus infection
397363 (TYK2)
05165 Human papillomavirus infection
397363 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
397363 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
397363 (TYK2)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
397363 (TYK2)
Protein kinases [BR:
ssc01001
]
Non-receptor tyrosine kinases
JAK family [OT]
397363 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
APH
FERM_C_FAK1
ABC1
RIO1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
397363
NCBI-ProteinID:
NP_001108142
Ensembl:
ENSSSCG00000013648
UniProt:
A0A8D1VBB5
Q684M7
LinkDB
All DBs
Position
2:complement(69157774..69183555)
Genome browser
AA seq
1184 aa
AA seq
DB search
MPLCHWGATTRGRKPDGDGAQPTATTEGLKVLLHWAGPGGGEPWVTFSEVTLTAEEVCIH
IAHRVGISPLCLNLFALFDAQAQVWLPPNHILDISGDSSLTLHFRMRFYFRNWHGMNPQE
PAVYRCGPPGTETSEQAEPGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFQ
NESLGMAFLHLCQLALRHGVPLEKVAKKISFKDCIPRSFRRQIRQHNALTRLRLRSIFRK
FLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCRLQLLAQAEGEPCYIRDGGQSS
PDPEPQAAPEPTTHEVLVSGTDGIQWRLVQAEGPSGGAGDGSSSRSPHTGHSGKKAKAQE
RGNQPVDRPGEALWTYFCNFQDITHVVLKERHVSIHCQDKCLELTLPSRATALSLVALVD
GYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLAKLRPEDGLYLIHWSTSHLN
RLILTVAQRDQAPGTKGLRLRKFPIELQAETVTLEGWGRSFPSVRELRAALQGCSLRAGD
DCFSLDRCCLPRPGEISNLIITRGPQACTRPLNLSHLSFHRVHQEDITQLSHLGQGTRTN
VYEGLLRVGGGGPEEEKSDGRDPSPSSGDRGQELRVVLKVLDPSHHDIALAFYETASLMS
QVSHVHLVFVHGVYVHGSENIMVTEYVEHGPLDVWLRRERGHVPLAWKLAVAQQLASALS
YLEDKSLVHGNVCGRNILLARLGQAEGTSPFIKLSDPGVGLNALSREERVERIPWTAPEC
LSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRGPSEKERFYQKQHKLPEPSCPELAT
LTSQCLTYEPAQRPSFRTILRDLTQLQPQNLADVLSVNPDLPTSDPTIFHKRYLKKIRDL
GEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGSQLRTGWRREIDILRTLYHEHIVKYK
GCCEDQGEKSVQLVMEYVPLGSLRDYLPRQNVGLAQLLLFAQQICEGMAYLHAQHYVHRD
LAARNVLLDNNRLVKIGDFGLAKAVPEGHDYYCVREDGDSPVFWYAPECLKECKFYYASD
VWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLEQGERLPQPEKCPHE
IYRLMKNCWEAKASFRPTFQNLVPILKTIQEKYQGQAPSVFSVC
NT seq
3555 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccattggggagccaccacccggggccgaaagcctgatggggatggagcc
cagcccacagccaccacagaaggcctgaaggtgcttctccactgggctggtcctggtggt
ggggagccctgggtcaccttcagtgaggtcacactgactgcagaggaggtctgcatccac
atcgcacacagagtcggcatcagtccactctgcctcaatctctttgccctcttcgatgcc
caggcccaagtctggctgcctccaaaccacatcttggatatttctggagactcgagcctg
acgctgcactttcgcatgaggttttatttccggaactggcatggcatgaatcctcaggag
ccagctgtgtaccgctgcgggccccccgggaccgagacctcagaacaggcagagccgggg
gtacaactcctggacccagcctcctttgagtacctctttgagcagggcaagcatgagttt
gtaaatgatgtggcatcgctgtgggagctgtcaagtgaggaggagatccaccactttcaa
aacgagagcctgggcatggccttcctgcacctctgccagctcgccctccgccacggtgtc
ccccttgagaaggtggccaagaagatcagcttcaaggactgcatcccgcgctccttccgc
cggcagatccggcagcacaacgctttgacgaggctgcgcctgcggagcatcttccgcaag
ttcctgcgggctttccagccgggctgcctctcacagcaggtcgtcatggtgaagtacctg
gccacgctcgagcgcctggcgccccgcttcggcacagagcgcgtacccgtctgccgcctg
cagctgttggcccaggccgagggcgaaccctgctacatccgggacggtgggcagtcctct
ccagaccccgagccccaggcggctccggaacccaccacccatgaggtgctggtgtcaggc
actgatggcatccagtggcggctggtacaggcagagggtcccagtggtggtgctggtgat
ggcagcagcagcaggagtccccatactggccattctggaaagaaagccaaggcccaagag
cggggcaaccagccagtggacaggcctggggaggccctgtggacctacttctgcaacttc
caggacatcacccacgtggtgctgaaagaacgccacgtcagcattcattgtcaggacaag
tgcttggagctgaccctgccttcccgggccacggccctgtccttagtggcactggtggat
ggctacttccgcctgacagctgactcaagccactacctgtgccacgaggtggctcctcca
cggctggtgatgagcatccaggatgggatccacggacctctgctggagccatttgtgctg
gccaagctgcggccagaggatggcctctacctcattcactggagcaccagccacctcaac
cgcctcatcctcacagtggcccagcgcgaccaggcacctggcacgaagggcttgcgcctg
cggaagttccccatagagctgcaggctgagacggtcacgctggagggctggggccggtcc
ttccccagcgtgcgggagctgcgggctgccctgcagggctgctctctccgggccggcgat
gactgcttttccctggaccgctgctgcctgccgaggccgggagagatctccaacctcatc
atcactcgggggcctcaggcctgcaccaggcctctcaacctcagccatctcagcttccac
cgggtccaccaggaagacatcactcagctgtcccacttaggccagggcacaaggaccaac
gtgtatgagggcctcttgcgagtggggggcggaggccccgaagaggaaaagtcagatggc
agggacccctccccatccagtggggaccgtgggcaggagctgcgagtggttctcaaggtg
ctagaccccagtcaccatgacatcgccctggccttctacgagacagccagcctcatgagc
caggtctctcatgtgcacctagtcttcgttcatggcgtctatgtgcacggctctgagaac
atcatggtgacggagtacgtggagcacgggcccctggacgtgtggctgcggcgggagagg
ggccatgtgcctctggcctggaagttggcagtggcccagcagctggcgagcgccctcagc
tacctggaagacaagagtctggttcatggcaacgtgtgtggccggaacatcctgctggca
cggctggggcaggcagagggcaccagccccttcatcaagctgagtgaccccggtgtgggc
ctgaatgccctctccagagaggagcgagttgagcggatcccttggacagccccagagtgc
ctgtctggtggagccaacagcctgagcactgcagcagacaagtggggctttggtgccacc
ctcctggagatctgctttgatggcgaggcccccctgcagggccgtggcccctctgagaaa
gagcgcttctaccagaaacagcacaaactgcctgagccttcctgcccagagctggccaca
ctcaccagccagtgcctgacctacgagccagcccagcggccatccttccgcaccatcctg
cgtgacctcactcagctgcagccccaaaatcttgctgatgtcttgtctgtgaacccggac
ctgccgacatcagatcccaccattttccacaagcgctatttgaaaaagatccgggacctg
ggcgagggtcactttgggaaagtcagcttgtactgctatgacccgaccaacgatggcact
ggtgagatggtggccgtgaaggccctcaaggctggctgcggttcccagctccgcaccggc
tggaggcgagagattgacatcctgcgcacgctctaccatgaacacatcgtcaagtacaag
ggctgctgcgaagaccaaggcgagaagtcagtacagctcgtcatggagtacgtgcccctg
ggcagcctccgagactacttgcctcggcaaaatgtcgggctggcccagctgctgctcttc
gcccagcagatctgcgagggtatggcgtacctgcacgcgcagcactacgtgcaccgagac
ctggccgcccgcaacgtgctgctggacaacaacaggctggtcaagatcggggacttcggc
ctagccaaggccgtgcccgaaggccacgactactactgcgtgcgcgaggatggggacagc
cctgtgttctggtatgccccagagtgcctgaaggagtgtaagttctactatgcctctgac
gtctggtcctttggggtcaccatgtatgagctgctgacctactgtgactccagccagagc
cccccctcgaaattcatcgagctcataggcctcacccaggggcagatgacagtgctgagg
ctcactgagctgctggaacaaggggagaggctgccacagccagagaaatgtccccatgag
atctatcgcctcatgaagaactgctgggaggcaaaggcctccttccgccccaccttccag
aacctcgtacctatcctgaaaaccatccaggagaaataccaaggccaggccccctcagtg
ttcagtgtctgctga
DBGET
integrated database retrieval system
