Sus scrofa (pig): 751859
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Entry
751859 CDS
T01009
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc00760
Nicotinate and nicotinamide metabolism
ssc01100
Metabolic pathways
ssc04068
FoxO signaling pathway
ssc04148
Efferocytosis
ssc04152
AMPK signaling pathway
ssc04211
Longevity regulating pathway
ssc04213
Longevity regulating pathway - multiple species
ssc04218
Cellular senescence
ssc04310
Wnt signaling pathway
ssc04922
Glucagon signaling pathway
ssc04936
Alcoholic liver disease
ssc05031
Amphetamine addiction
ssc05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
751859 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
751859 (SIRT1)
04068 FoxO signaling pathway
751859 (SIRT1)
04152 AMPK signaling pathway
751859 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
751859 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
751859 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
751859 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
751859 (SIRT1)
04213 Longevity regulating pathway - multiple species
751859 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
751859 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
751859 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
751859 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ssc03036
]
751859 (SIRT1)
03029 Mitochondrial biogenesis [BR:
ssc03029
]
751859 (SIRT1)
Enzymes [BR:
ssc01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
751859 (SIRT1)
Chromosome and associated proteins [BR:
ssc03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
751859 (SIRT1)
Mitochondrial biogenesis [BR:
ssc03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
751859 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
751859
NCBI-ProteinID:
NP_001139222
UniProt:
A0A4X1TRZ2
A7LKB1
LinkDB
All DBs
Position
14:71091167..71126351
Genome browser
AA seq
742 aa
AA seq
DB search
MADEAALALQPGGSPSAVAAEREAPSPPAGEPLRKKPRRDGPGVGRSPGEPGGAALEREL
PAAAGGCPAAAVLWRETAAGGEREAQAAAAAGEGNNGPGLQGLSREAPPADDFYDDDDDD
EGEEEEEAAAAAAIGYRDNLLFGDEIVTNGFHSCESDEDDRASHASSSDWTPRPRIGPYT
FVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDA
VKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDP
RPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSF
ATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAM
KYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVII
NELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEGSSSPERTSP
PASSVTLPLLDQATKSNVDDLDVSESKDCVEEKSQEVQTSRSIESVKEPMESPGLKNVAC
SNGEKNERTSVAETVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDDV
LSSSSCGSNSESGTCQSPSLEEPMEDESEIEEFYNGLEDDADVNMRAGGTGFGADGSDQE
AVNEAISMKQEATGVNYPSNKS
NT seq
2229 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcccttcagcccggcggctccccctcggcggtggcggct
gagagggaggccccgtcgccccccgccggggagccgctccgcaagaaaccgcggagagac
ggcccgggcgtcgggcggagcccgggcgagcctggtggggcggccttggagcgtgagctg
ccggcggcggcgggcggctgcccggcggcggcggtgctgtggcgggagaccgctgcgggc
ggggagcgggaggcccaggcggctgcggcggcaggagaaggaaacaatgggccgggctta
cagggcctatcccgggaggcgcccccggccgacgacttctacgacgacgacgacgacgac
gagggcgaggaggaggaagaggcggcggcagcggcggctattgggtaccgagataacctt
ctgtttggtgatgaaatcgtcaccaatggtttccattcttgtgaaagtgatgaggatgat
agagcctcacatgccagttctagtgactggactccaagaccacggataggtccatatact
tttgttcagcaacatctcatgattggcacagatcctcgaacaattcttaaagatttgcta
ccagaaacaattcctccacctgaattggatgatatgacactgtggcagattgttattaat
atcctttcagaaccaccaaaaaggaaaaaaagaaaagatattaatacaattgaagatgct
gtgaaattactacaagagtgcaaaaaaataatagttctaactggagctggggtttctgtt
tcttgtggaatacctgacttcaggtcaagagatggcatttatgcacgccttgcagtagac
tttccagaccttcctgatcctcaagcaatgtttgatattgaatatttcagaaaagatcca
agaccattcttcaagtttgcaaaggaaatatatcctggacagttccagccatctctctgt
cacaaattcatagccttgtcagataaggaaggaaaactgcttcgcaactatactcagaac
atagatacactggaacaggttgcaggaatccagaggataatccagtgtcatggttccttt
gcaacagcatcttgcctgatttgtaaatataaagttgactgtgaagctgtacgaggagat
atttttaatcaggtggttcctcgatgtcctaggtgcccagctgatgaaccacttgctatc
atgaaaccagagattgtcttttttggtgaaaatttaccagagcagtttcatagagccatg
aagtatgacaaagatgaagttgatcttctcattgttattgggtcttccctgaaagtaaga
ccagtagcactaattccaagttccataccccatgaagtgcctcagatattaattaatagg
gaacctttgcctcacctgcattttgatgtagagcttcttggagactgtgatgtcattatt
aatgaattgtgtcataggttaggaggtgaatatgccaagctttgctgcaaccctgtaaag
ctttcagaaattactgaaaagcctccacgaacacaaaaagagttggctcacttgtcagag
ttaccacccacacctcttaatatttcagaaggctctagttcaccagaaagaacttcacca
ccagcttcttcagtgactctccctcttttagaccaagcaacaaagagtaatgttgatgat
ctagatgtgtctgagtcaaaagactgtgttgaagagaaatcacaggaagtacagacttct
aggagcattgaaagtgttaaagaaccgatggagagtccaggtttgaagaatgttgcctgc
agtaatggagagaaaaatgaaagaacttcagttgccgaaacagtaagaaaatgctggcca
gctagacttgcaaaggagcagattagtaaacggcttgatggtaatcagtatctgttttta
ccaccaaaccgttatattttccatggcgctgaggtatattcagactctgaagatgatgtc
ttatcctctagttcttgtggcagtaacagtgagagtggaacttgccagagtccaagtcta
gaagaacccatggaggatgaaagtgagattgaagaattttacaatggtttggaagatgat
gctgatgttaatatgcgagctggaggaactggatttggagctgatggaagtgaccaagag
gcagttaatgaagctatatccatgaaacaggaagcaacaggcgttaactatccatcaaac
aaatcataa
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