Sus scrofa (pig): 780403
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Entry
780403 CDS
T01009
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc05012
Parkinson disease
ssc05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
780403 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
780403 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
780403 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ssc04131
]
780403 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ssc04147
]
780403 (LRRK2)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
780403 (LRRK2)
Protein kinases [BR:
ssc01001
]
Serine/threonine kinases: TKL group
LRRK family
780403 (LRRK2)
Membrane trafficking [BR:
ssc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
780403 (LRRK2)
Exosome [BR:
ssc04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
780403 (LRRK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
LRR_4
COR-B
Ras
COR-A
LRR_14
ARMC6
LRR_9
Arf
LRR_NXF1-5
WD40_2
Beta-prop_ACSF4
LRR_13
Beta-prop_IFT122_1st
Beta-prop_EML_2
Beta-prop_WDR36-Utp21_1st
Ank_2
T2SSE
nSTAND3
WD40_CDC20-Fz
LRR_6
AAA_22
AAA_16
Kdo
ABC_tran
PduV-EutP
G-alpha
GTP_EFTU
NACHT
AAA_7
MobB
TrwB_AAD_bind
MMR_HSR1
Beta-prop_THOC3
WD40_Prp19
AAA_29
NB-ARC
FtsK_SpoIIIE
TniB
ARM_CUL7_CUL9
nSTAND_NTPase5
Motif
Other DBs
NCBI-GeneID:
780403
NCBI-ProteinID:
NP_001106908
Ensembl:
ENSSSCG00000000784
UniProt:
A9XXE0
LinkDB
All DBs
Position
5:71800337..71945828
Genome browser
AA seq
2526 aa
AA seq
DB search
MASGSCQGCEEEDEEALKKLIVRLNNVQEGKQIETLVQILEDMLVFTYADHASRLFQDKN
VHVPLLIVLDSYMRVASVQQVGWSLLCKLIEICPNTMQSLMGPQDIGHDWEALGIHQLIL
KMLTVHNASVSLSTVGLKALDLLLTSGKITLLILDEESDIFLLIFDAMRTFSANDEVQKL
GCKALHVLFERVSEEQLTEFVENKDYVILLSALKKFKDEEEIVLHVLHCLHSLAIPCSNV
EVLMSGNVRCYNIVVEAMKAFPVNEKIQEVSCCLLHRLTLGNFFNILVLNEVHAFVVRAV
QQYSENAVLQIAALSSLALLTETIFLNQDLEEKNENQENDDEEEDKLFWLEACYKALTWH
RKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASAN
ALSTLLEQNVNFRKILLSKGIYLNVLELMQKHIHSPEVAESGCKMLNHLFEGSNTSLDTM
AAVAPKIITVMKSHETSLSVQLEALRAILHFIVPDITEESREDTEYQHKLNMVKKQCFRN
DIHKLVLAALNRFIGNPGIQKCGLKVISSLAYFPDALEVLSPEGAIDSVLHTLQMYPDDQ
EIQCLGLSLIGCLVTKKNLCLGTGHLLAKILISSLQRFKDIGEVQIKGFQTILTILEMSV
SFSKLLVNHSFDSVIFHQMSSGMEQKDQQFLNLCCKCFAIVAMDDELKSVMLERACDQNN
SIMVECLLLLGADVNCAKEATSLIYQVCEKASSPKLVELLLNSGSREQDVRKALTISIGK
GDSQVISLLLRRLALDLANNSICLGGFCMGKIEPSWLGPLFPDKTSNLRKETNVGSTLAR
MVLRYQMKSAVEEGAASGSRRNLSEEILDKFDEWTFIPDSYVDSVFGQSDDLDSEGSEGS
FLVKKKANSISVGEFYRDAALQRCSPNLQRHSNSLGPMVDYEDLLKRKRKILSSDDSLRT
SKLQSHVRHSDSVSSLASERENITSLDLSANELKDIDALSQKSCISGHLEHLEKLELHQN
ALTSFPQQLCETLKCLTHLDLHSNKFTSFPSYLLKMNCIANLDVSRNDIGPSVVLDPAVK
CPTLKQFNLSYNQLSSLPENLSDVVEKLEQLILEGNKISGVCLPLSLKELKILNLSKNRI
SSFSEDFLEACPQVESLSARMNFLAAMPFLPSSMTSLKLSQNRFTCVPEAILNLPHLRSL
DMSSNDIKYLPGPVHWRSMNLRELLFSHNQISTLDLSEKACAWSRVEKLHLSHNKLKEIP
PEIGCLENLTSLDVSCNLELRSFPNEMGKLSKIWDLPLDDLHLNFDFKHIGCKAKDIIRF
LQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMRIKKSDLGMQGATVGIDVKDWPIQIR
GKRKKDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKAR
ASSSPVILVGTHLDVSDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAKLR
KTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVKEYQ
LQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKVMAQILTVKVEGCPKY
PKGIISRRDVEKFLSKKKRFPKNYMSQYFKLLEKFQIALPTGEEYLLVPSSLSDHRPVIE
LPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYLN
WSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDIC
GEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEGGDLLVNPDQPRLTIPISQIAPDLTL
ADLPRNIMLNSDELKFEQAPEFLLGDGSFGSVYRATYEGEEVAVKIFNKHTSLRLLRQEL
VVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVADG
LRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAP
EVARGNVIYNQQADVYSFGLLLYDILTTGGRIAEGLKFPNEFDELAIQGKLPDPVKEYGC
APWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMRRMSIPKNFIVECMVASNHN
SKNASVWLGCGHTDKGQLSFLDLNTERYTSEEVTDSRILCLALVHLPLEKESWIVSGTQS
GVLLVINTEDGRKRHTLEKMTDSVTCLYCNSFSKPSKQKNFLLVGTADGNLAVFEDKSVK
CKGAAPLKILSIGNVSTPLMCLSESMNLTEKNIMWGGCGTKVFSFSDDFTIQKLIETRTN
QLFSYASFSDSNIIAVVVDTALYIAKKNSPFVEVRDKKTEKLCELIDCVHFLKEELAKAN
KELKHKLSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRIMRIIHNFCDSVRAMMTT
QLGSLKNVMLVLGYNRKSAEGIQHQKEIESCLSIWDINLPHEVQNLEKHIEVRKELAEKM
RRISVE
NT seq
7581 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagctgccaggggtgcgaggaggaggacgaagaagctctgaagaaactg
atagtcaggctgaacaatgtccaagaaggaaaacagatagagacgctggtccaaatcctg
gaggatatgctggtgttcacttacgccgaccacgcctccaggttatttcaagacaaaaat
gtccacgtgcctctgttgatcgtcttggactcgtatatgagagtcgctagtgtgcagcag
gtgggttggtcacttttatgcaaattaatagaaatctgtccaaatacaatgcaaagctta
atgggaccccaggatattggacatgattgggaagcccttgggattcaccaactgattctt
aaaatgctcacagttcataatgccagtgtcagcctgtcaacagttggattgaaggcctta
gatcttctcctaacttcaggtaaaatcactttgctgatactggatgaagaaagcgatatt
ttcttgttaatttttgatgccatgcgcacattttcagccaatgatgaagtccagaaactt
ggatgcaaagctttacatgtgctgtttgagagagtttcagaggagcaactgactgaattt
gttgagaacaaagattacgtgatcttgctgagtgcattaaagaagtttaaagatgaagag
gaaattgtgcttcatgtactgcactgtttacattccctagcaattccttgcagtaatgtt
gaagtcctcatgagtggcaatgtcaggtgttataatattgtggtagaagccatgaaagca
ttccctgtcaatgagaaaattcaagaagtgagttgttgcttgctccatagacttacatta
ggtaatttttttaatatcctggtattaaacgaggtgcatgcatttgtggtgagagctgta
cagcagtattccgagaatgcagtcctgcaaatcgcagcactcagctctttagctctcctc
actgagaccattttcttaaatcaagacttagaggaaaagaatgagaatcaagaaaatgat
gatgaggaagaagataaattgttttggctggaagcctgttacaaagcattaacgtggcat
aggaagaacaagcacgtgcaggaggctgcatgctgggccctaaacaatctccttatgtac
cagaacagtttacatgagaagattggagatgaagatggccagttcccagcccacagggaa
gtgatgctgtccatgctgatgcactcttcatcgaaagaagtcttccaggcatctgcaaat
gctttgtcaactctgttagaacaaaacgttaatttcagaaaaatcctgttgtcaaaagga
atatatctaaatgtattggagttaatgcagaagcatatacattctcctgaagtggctgaa
agtggctgtaaaatgctaaaccatctctttgagggaagtaacacttccctggatacaatg
gcagcagtggcccccaaaataataacagttatgaagagtcatgagacatcattatcagtg
cagctggaggcacttcgagctattttacattttatagttccagacatcacagaagaatcc
agggaagatactgaatatcaacataaactaaatatggtgaaaaaacagtgtttcaggaat
gatattcacaaattggtcctggcggctttgaacaggttcattggaaatccagggattcag
aaatgcggattaaaagtaatttcttctctagcatattttcctgatgcgttagaagtatta
tccccggaaggtgctattgattctgtgcttcacacgctgcagatgtatccagacgaccaa
gaaattcagtgtctgggtttaagtcttataggatgcttggttacaaagaagaacttatgc
ctaggaactggacatctgctggcaaaaattttgatttccagtttacagcggtttaaggac
attggtgaagtacagattaaaggatttcagacaattttgacaatactggaaatgtcagtg
tctttttccaagctgctggtgaatcattcctttgattcagtaattttccatcagatgtcc
tctggtatggagcaaaaggatcaacagtttctaaacctttgttgtaagtgctttgcaata
gtggctatggacgatgagttgaaaagtgtgatgctggagagagcatgtgatcagaataac
agcatcatggtcgaatgcttgcttttattgggagcggatgtcaattgtgcaaaagaggca
acttctttaatttatcaggtatgtgagaaagcaagtagtcccaaactggtggaactgtta
ctgaatagtggatcccgtgagcaagatgtacggaaagctttgacaatcagcattggaaaa
ggcgacagccaagtcatcagcttactcttaaggaggctcgccttggatctggccaataat
agcatatgtcttggaggattttgtatgggaaaaatcgaaccttcttggcttggtccttta
tttccagataagacatctaatttaagaaaagaaacaaatgtaggatccaccctagctaga
atggtgcttagatatcagatgaaaagtgctgtggaagaaggagccgcttcaggcagcaga
aggaatctttctgaagaaatacttgataaatttgatgaatggacctttattcctgactct
tatgtggatagtgtgtttggtcaaagtgatgacctagatagtgaaggaagtgaaggctca
tttcttgtgaaaaagaaagcaaattcaatcagtgtaggagagttttaccgagatgctgcc
ttgcagcgttgctcaccaaatttgcaaagacattccaattcattgggacccatggttgat
tatgaagatttgctgaagagaaaaagaaagatactatcttcagatgactcactcagaaca
tcaaaactccaatcacatgtgaggcattcagacagcgtttcttccttggcttctgagaga
gaaaacattacatcattagacctctcagcgaatgaactaaaagatattgatgccctgagc
cagaaatcctgcatcagtggtcatttggagcatcttgaaaagctggagcttcaccagaat
gcactcacgagcttcccacaacagctatgtgaaactctgaagtgtttgacacatttggac
ttgcacagtaataaatttacatcatttccttcttacttgttgaaaatgaactgtattgcc
aaccttgatgtctctcgaaatgacattgggccctctgtggttttggatcctgctgtgaag
tgcccgaccttgaaacagtttaacctgtcctacaatcagctgtcttctcttcctgagaac
ctcagtgatgtggtagagaaactggaacagctcattttagaaggaaataaaatatcagga
gtatgtttgcctttgagcctgaaggaactgaagattttaaaccttagtaagaaccgcatt
tcatctttctcagaggactttcttgaggcttgtcctcaagtggagagtttaagtgccaga
atgaattttcttgctgctatgccatttttgccttcatccatgacaagcctaaaattatct
caaaacagatttacatgtgttccagaagcaattttaaatcttccacacctacggtcctta
gacatgagcagcaatgatattaaatatctaccaggtcctgtgcactggagatctatgaac
ttaagggaactcttgtttagtcataatcagatcagtaccttggacttgagtgaaaaagca
tgtgcatggtctagagtagagaaactacatctttctcataataaactgaaagagattcct
cctgagattggctgtcttgaaaatctgacatcgcttgatgttagttgcaacttggaactg
agatcctttcccaatgaaatggggaaattaagcaaaatatgggatcttcctttggatgat
ctgcatcttaattttgattttaaacatataggatgtaaagccaaagacatcataaggttt
cttcaacagcggttaaaaaaggctgtgccctataatcgaatgaaacttatgatagtggga
aacactgggagtggtaaaaccaccttattacagcaattaatgagaatcaagaaatcagat
cttggtatgcaaggtgccacagttggcatagatgtgaaggactggcccatccaaataaga
ggcaaaaggaagaaagacctcattctaaatgtgtgggattttgcaggtcgtgaggagttc
tacagcacccatccccactttatgacccagcgagctctgtaccttgctgtctatgaccta
agcaaagggcaagctgaagttgatgccatgaagccttggctcttcaatataaaggctcgt
gcttcttcttcccctgtgattcttgttggcacacatttggatgtttctgatgagaagcag
cgcaaagcctgtataagtaaaatcaccaaggaactcttgaacaaacgcgggtttcctgca
atccgggattaccactttgtaaatgccaccgaggaatcagatgctttggcaaaacttcgg
aaaaccatcataaatgagagcctcaatttcaagatccgagatcagcctgttgttgggcag
ctgattccagactgctatgtagaacttgagaaaatcattttatcagagcgtaaaaatgtg
ccaattgaatttcctgtaattgaccggaaacgattattacaactcgtgaaagaatatcag
ctgcagttagacgaaaatgagcttccgcatgcagttcacttcctaaatgaatcaggtgtc
cttcttcattttcaagacccagcgctgcagttaagtgacttatattttgtggaacccaag
tggctttgtaaagtcatggcgcagattttgacagtgaaagtggaaggctgtccaaaatat
cctaagggaattatttcccgtagagatgtggaaaaatttctttcaaagaaaaagagattt
ccgaagaactacatgtcacagtactttaaacttctagaaaaattccagattgccttgcca
acaggagaagaatatttgctggttccaagcagcttgtctgaccacaggcctgtgatagag
cttcctcactgtgagaactctgaaattatcattcgactctatgaaatgccttattttcca
atgggcttttggtcaagattaatcaatcgattacttgaaatttcaccctacatgctttca
ggaagagaacgagcacttcgcccaaacagaatgtattggcgacaaggcatctacttgaat
tggtctcctgaagcttattgcctggtaggatctgaagtcttagacaatcaccctgagagt
ttcttaaaaattacagttccttcttgtcgaaaaggctgtattcttttgggccaagttgtg
gaccacattgattctctcatggaagagtggtttccggggttactggagattgatatttgt
ggtgaaggagaaactctgttgaagaaatgggcattatatagttttaatgatggtgaagag
catcaaaaaatcttacttgacgacttgatgaagaaagcagaaggaggagaccttctagta
aatccagatcaaccaaggctcactattccaatatctcagattgcccctgacttgactttg
gctgacctgcctagaaatattatgttgaatagtgatgaactgaaatttgaacaagctccc
gagtttctcttaggtgatgggagttttggatctgtttatcgagcaacctatgaaggagaa
gaagtggctgtgaagatttttaataaacatacgtcacttagactgttacgacaggagctg
gtggtactttgccacctccatcaccccagcttaatatctttgctggcggctgggattcgt
cctcggatgttggtgatggaactcgcctccaagggttcactggatcgcctgcttcagcaa
gacaaagccagtctcaccagaacactgcagcacaggatcgcgctccacgtggccgatggc
ttgagataccttcactcagccatgattatataccgtgacttgaagccccacaacgtgttg
cttttcaccctgtatcccaatgctgccatcatcgccaagattgctgactatgggattgct
cagtactgctgtagaatggggataaaaacgtcagagggcacaccagggtttcgtgcacct
gaagttgctagaggaaatgttatttataaccaacaggctgatgtttattcatttggtttg
ctactctatgacattttgacaactggaggtagaatagcagagggtttgaagtttccaaat
gagtttgatgaactggcaatacaaggaaaattacctgatccagttaaggaatatggttgt
gccccatggcctatggttgagaagttaattaaaaagtgtttaaaagaaaatcctcaagaa
agacctacttctgcccaggtctttgacattttgaattcagctgagttaatctgtctgatg
agacgtatgtcaatacctaaaaacttcattgtcgaatgcatggttgcctcgaatcataac
agcaagaacgcaagcgtttggctgggctgtgggcacactgacaaaggacagctctcattt
cttgacttaaatacggaaagatatacttctgaggaagttactgatagcagaatactgtgc
ttagccttggtgcatcttcctcttgaaaaggaaagctggattgtgtctggaacacagtct
ggtgtgctcctcgtcatcaatactgaagatgggagaaagaggcacaccctggaaaagatg
accgactctgttacttgcttgtattgcaattccttttccaagcctagcaagcaaaaaaat
ttccttttagtgggaactgctgacggcaacttagcagtttttgaagataaaagtgttaag
tgtaaaggagctgctcctttgaagatactcagcataggaaatgtcagtactccactgatg
tgtttgagtgaatccatgaatttaactgaaaaaaacattatgtggggaggatgtggtaca
aaagttttctcgttttctgatgacttcaccattcagaaactcatcgagaccaggacaaat
caactgttttcttatgcatctttcagtgactccaacatcatagcagtggtggtagacaca
gctctttacattgctaagaaaaatagcccttttgtggaagttcgtgacaagaagactgaa
aaactctgtgaactaatagactgtgtgcactttttaaaggaggaactggccaaagcaaac
aaggaattgaaacacaaactgtcttattctgggagagtgaaaactctctgcctccagaag
aacactgctctctggataggaactggtggaggccatatcttactccttgatctttcaact
cgtcgaattatgcgtataattcacaacttctgcgattctgtcagagccatgatgaccaca
cagttaggaagccttaaaaatgtcatgctggttttggggtataaccggaaaagtgctgaa
ggtattcaacaccaaaaagagatagagtcttgcctgtctatttgggacatcaatcttcca
catgaagtacaaaatttggaaaaacatattgaagtgagaaaagaattagctgaaaaaatg
agaagaatatctgttgaataa
DBGET
integrated database retrieval system
