KEGG T10651: 133992090

Scomber scombrus (Atlantic mackerel): 133992090

Entry

133992090         CDS       T10651

Symbol

dst

Name

(RefSeq) dystonin

K10382

dystonin

Organism

ssco Scomber scombrus (Atlantic mackerel)

Pathway

ssco04382

Cornified envelope formation

Brite

KEGG Orthology (KO) [BR:ssco00001]
09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    133992090 (dst)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:ssco04812]
    133992090 (dst)
Cytoskeleton proteins [BR:ssco04812]
Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filament-binding proteins
    133992090 (dst)

SSDB

Motif

Pfam:

Spectrin SR_plectin_7 CH Spectrin_2 GAS2 Spectrin_3 Spectrin_SYNE1 SH3_10 EF-hand_1 EF-hand_6 EF-hand_7 Spectrin_4 EF-hand_5 Spectrin_1st_PEPL MitMem_reg KIF9

Other DBs

NCBI-GeneID:

133992090

NCBI-ProteinID:

XP_062286760

LinkDB

Position

12:12987780..13096565

AA seq 5670 aa
MIAAAFLVLLKPYSIQCVLLLLLLLLGTIATILFFCCWHRRLRNGKHPMKSVLSGRSKSR
VGLRTHHFRSECFRHSPRHARRSLHARATEEKPNLVEVPESDPDSSSTLRKRKVKKRVLP
EFYQSVQVTPTRKPSSSSGNPSLHCSMSSSADFSDEDDYSLKSGSASPAPGDTLPWNLPR
HERSKRKIQGGSVLDPAERAVLRIADERDRVQKKTFTKWINQHLLKVRKHINDLYEDLRD
GHNLISLLEVLSGDTLPRERGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKL
TLGLIWTIILHFQISEIHVTGESDDMTAKERLLFWSKQITEGYVGVRCDNFTTSWRDGRL
FNAIIHKYRPDLVDMSCVSTQTNRSNLENAFGVAEQLGVARLLDPEDVDVQSPDEKSVIT
YVSTLYDAFPKVPEGVDGISANDVDIKWVEYQNMIKYLSQWIKHNVIVMSDRSFPNNPVE
LKALYTQYLQFKEHEIPLKENEKTKIKILYKMLEMWIEFGRIQLPPGHHPNDVEKEWGKL
IVAMLEREKSLRPEVERLEMLQQIANRVQRDCVNGEDKLALARTSLQSDAKRLESGIQFL
NEAEIAGYLLECENILRQQVVDIQILLDGKFPFADQLVQRVSKLRDDLLALRAECSSVYN
QGRTLTTEQTKMMISGITQSLNSGFSQNINTGLTPALTPALTPGGLGTPGSTFTSSLTPC
LTPSLTPALTPGLQPASVQTYVGSGGIDPGSLKNLKHMQIRKPLLKSSLADSNMTEEEVN
MKFVQDLLNWVEDMQLQLDRSEWGSDLPSVEMHLENHKTVHRAIEEFQMSLKDAKLSEIQ
MNIPLKISFSEKLNKLENQYERLLSCSRERQSHLESLHDFVSLATQELIWLNEKEEEEVA
FDWSDRNSNVSKKKEYHADLMRELDEKEEVIKSVQDKAERLLLKNHPARLTIEAYKAAMQ
TQWSWILQLCSCVEQHLKENAVYFEFFSEAKESMDYLKSLQDAIQRKYSCDRTSSLHRLE
DLIQESMDEKEQLLQYRSTVAGLVGRTKNIVQLRPRNPDSPVRSSIPVKAICDYRQIEIT
IYKDDECVLANNSHRAKWKVINPAGNEAMVPSVCFTVPPPNKEAVDMAARIEQLYQNVLA
LWHHSHINMKSVVSWHYLMADIRAIRNWNVASIKTMLPGEHQQVLSNLHSHFDEFLEDSE
ESEVFTVADCTQLERDVAACKEYYQELLRSAEREEHEESVYNNYISEIRNFRMHLEAHEE
HLIRQIRTPLERDDLEQSLQRITEHERKTAELNKLKEDLDVMKEKCELFLRQATGSPSAP
TLSSELTVLVQSMSQVYSMSSIYMDKLKTVSLVVKHSQRAEALVKAYESKLYEEDAMNSD
LKSIETVISTLKQWRTEIDENQEVFHDMEDELQKARVISDRMFKAHNERDFDLDWHKEKA
DQLNERWHNIHSQVDNRLRDLDGISKSLKHYRDSYSSLDEWVTEMEAAQLKAQENKPEDS
KALAELLNKQKVLVAEIEQKQSRMDECQKYSEQYSSSIKDYELQLMTFRAMVDSQHKSPL
KKRKMQSSSDVIQQEFMDLRTRYTALVTLMTQYVKFASETLKRTEEEERSVDEEKREHGD
KVSKLLHWMSNVKQGQNNDGNALTDSNANTDASNKPQVSVEEMVTKKEQIAEALRATQMM
LNKHSEKMTEEEREKAQEQLKALNQAYNELSQQCSEQTTSAEEALLERHKEFTEKLEDVC
DNLTLTENRLIGHQQQADSAGCITDLQQYQQEHQALQKDVLTNASALNEVITSTKKFLEE
NRSKLTPDQIAIIESKLEEAKSKAKLINQRAEESRKDLEKVVTTAIKQESEKAAAVERLE
ESKNKIEGLLDWISNIGNENESGLDKTDHISKENGNLPEEKSAMGLIAENDDANGNALQT
TESDFGKESDGKNDASLDKQYDRVKARHQEILSQQQDLIMATQSAQALLDKQANVLAPEE
KEKLQKNIQELKGRYEASLTQAEQQMKQVQCVQEELKKFQDDCEEFEGWLDQAEREIEEL
RAPEASLNILSDKLQRQKSFSEDVISHKGDLRFITISGQKVLDVAKTCGLDDPAGKNYPL
HMDTSGTCSAVKDQLDSAAGRYKKLHSQCNQLGNNLKDVVDKYNRYEDSNAGLLKWLNSS
EEEARKQQSEAIAADPQTLQKQLEETKALQGQMTGHQTAVDTLCKTAESLITSEGDLLSN
PDEIQETVDDIVERYDNLSKSVSDRNEKLQITLTRSMSVQDGLDEMMGWMEGVENSVKEK
EQIPLDSASIGDILSKEAALEQDIASRHSSISAMKAKVKKFVETADPSAAALLQSKMDAL
SQRFSDACDKHKQKVSQLEQLKEKVELFENIADKAQQFVVKRSQDLHETDGPGKTFNELS
QLMENTKAEMAEHASDLEKLQTLSNELSEISLDGNKAQIQSKMDNLLNIFTTFKDTVKEK
EDEVSTCQDQLGEFRSAASALTKWLEETTEKVPVVQPSSSEKSLEKDLQTVTGLLDEWTS
KGPAVQDLNSKGSSLCSLISFLTSPAKTKTPNKSALTNGGGPASHSYLTNKELMVIQQNM
SFINEGYTSLGETLKNRASELSSSVQEVKGAQKDVDDMMAWLKDMKNTAASWNNAATEKD
SVKTQLEQQKAFEDDMKQKQEQLQKLREKLLNLIETHPNSPEAAKWKQMLAEIDAAWADI
SGSVEERKQHLEQSNKNLDIFKTTELQLGQWLSEKELMMSVLGPLSIDPNMLKMQKQQVQ
ILQNEFKSRKPQYEQLEEAASAILSSSGHQAPSNGKLVREQLTAVTQKWQGLTGQLDQRD
SLIDQAVVKTGQFQDLLRSLSQTTTQLENQLTNHQAHSTQPDAVKKQLEEVQNISAQLRE
EKKKLKEAEAINAELTAMVTEDYLKADLARQLESVSKPFKQLEEKAAKQIEQLSSTFASS
QQFHQTSKDFQSWLGENLQDQSKPQHISAKVEVLQQTLEEHSKLQKALSEHEEAYNTIIG
EGEMLLQNTDGAEKLALQGQLTTLSSNWQEVKKNSVEQADKLQTALQRSQKYQEHAEKLN
TWIQECEASEDRVKLTVDPAAVESSISQVKALQKDIDKHRGMMEQLNTAADSLLEVANID
TEDIKEEKDSIGKRVENVEEGLQSKRESLEKISHTIKEFNDAYKEAKGQLEGAKKQVDAY
ESQGVQAHSNKNLTNMKAQHKSMAGVQNQVEHLKNLAKDLVVDVPDADGVTDLLLQADSI
ETDYSTLNDKLEKTCQVLEGKLQGIGQFQNNIREMFSRFTDLDDELDSMAPVALNLAVLK
EQQDNIGSFLTKLQELMANTANAGDSCKKMLETESSPDLLGLKRDLDTLSKQCGKLMDRA
KGKETQVQSTLTKLEELYGKLHQVEDKLSGAVEKEASQEAVGMETDVINQQLEAFKAFQK
EEIDPLQTQLQDISSLGQGLIQNAAKGTNTKKLEDDLENVNTKWNTLNKKIAERSAQLHE
ALLHCGRFQDALESLLSWLTDTEELMANQKPPSAEFKVVKAQIQEQKLLQRLLDDRKPTV
ELIKKEGGKVAELAESVDKEKVAKEIECLGQRWDTLLKKAENRHKQLESILVVTQQFHET
LEPLSEWLTATEKHLSHSEPIGTEICKLEDQISQHKALEEEIMNHSKDLLQVVSLGQMLK
TVSSVDNKDFVQSKLDATQASYIELQERCRRKAEMLQQARVNAQLFGEDEVALMNWLNEA
HTQLDEVSVEDYKIDVLENQLAEQRTLQSDIELRKKNVDQAIANGMELLKQTTGDEVVVI
QGKLDGIKTKYAEINSMSNNVLKTLEQVLSLSSKLQHSHEDLRSWLEKAEAEIHAFADQE
PLGDQLIHAQNKQKALLKETKDQKPAIDKLNEVSSSLLDLIPWHAREGLDKLVTEDNERY
RAVCDSITQQVDQINANILKSQQFEQAADTELAWLTDAERKLLSVGEIRLEQDQTTAQLQ
AQKIFSMDIMRHKDAVDEIVKTGKAIMNIKNPEEKEVVKAKTQTLLEKYGVVSQLNSERC
LQLERAQSLASQFWETYEELSPWLQEILNTFSQLPPPAIEYETLRQQQEELRQMRELIAE
HKPHIDKMNKTGPQLLELSPVEGVPIREKYTVADQLYTQLKADVKERAATLDEAISKSTQ
FHDKIDPMLESLERIAERLHQPPSISVEVDKIKEQITENKSVTVDLEKLQPSYEMLRQRG
EEMIARSEGADKDISAKAVQDKMDQMVFLWNDIQALLEEREAKLLDVMDLADKFWCDHCA
LIATIKDSQDLLRELEEPGVDPSVVKQQQEFVESFKEEIDGLQEELDTVRNQGEELMTAC
GEPDKPVIKKSLDEVNSAWENLNKTWKERVERLEEAMQAAVQFQDGLQGMFDWVDILEGK
LDSMSPVGTDLETVKQQIVELKEYKGESYQLQIEMERLNHQAGLLLKKVTEDADRCAIQE
PMSELKMLWNNLDEKIISRQHKLEGGLLALGQFQHALDELLAWMSHTEELLNEQRKTGGD
PKAIEIELAKHNVLQIDVLAHKTTVETVNKAGNELVESSAGEEASALQSKLENLNQRWKA
IQEKAAQRKQQLESALIQAQGFHGEIEDMQQWLKDTERQLLASKAVGGLPDTAREQLNAH
LELCSAFEVKEELYQELMNKGQQVLILMPEGPDSNTEQDLTNLKEKWETVQAKVAERKGK
LEEALTLATDFHNSLQDFINWLTQAEQTLNMVSPASLILETIMFQIDEHKMFVTEVNSHR
DHIIELDKTGTHLKYFSQKQDVVLIKNLLLSVQSRWEKLVQRSVERGRLLDDARKRAKQF
HESWSKLMEWLEESEKSLDSEVEIANDPDKIKTQLSQHKEFQKALGSKHSVYDTTVRTGR
ALKDKTSLQDDKQKLDDMLSELRDKWDTVCGKSIERQNKLEEALLFSGQFTDALQALIDW
LYRVEPQLAEDQPVHGDIDLVLNLIDNHKVFQKELGKRTVSVQALKRSAKELIESSHDDS
SWVKVQMQELSTRWETVCNLSVSKQARLEQALCQAEEFHSTVHILLEWLAEAEQILRFHG
SLPDDEEALRALIDQHKEFIKKLEEKRVALNKATSLGEAILTICHPDSITTIKHWNTIIK
ARFEEVQAWARQHQQRLATALGELLATQELLENLLTWLQWAESNLNDKDKEIIPQEIEEV
KSLIAEHQAFMEEMTRKQPDVDKITKTHKRKAALEPQIQSQIPVLDKGRAGRKRSPTQTM
YASATQPPIETKNPRVNLLVTKWQHVWLLALDRRRKLNDALDRLEELKEFANFDFDVWRK
RYMRWMNHKKSRVMDFFRRIDKDQDGKVTRQEFIEGILSSKFPTSRLEMSAVADIFDRDG
DGYIDYYEFVAALHPNKDAYKPLTDADKIEDEVTRQVAKCKCPKRFQVEQIGANKYRFYL
GNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRAKGRTNMELREKFILPEG
TTQVMASFRYRGRRSRPSSRGASPNRSTSSQSCAIPSAPAVTSTPKTTQHITRNYDKPWL
TNSKPSTPLKSSDSFGSQGSSSEGTPVQGSKLRLPGYLSGKGFQSGEEGTLISAAVLKAR
GQTIGESRRNSSRPGSKAGSRGSSRRGSDASDFDISDIQSVCSDMSETVGDSSRATPRSA
SRQQRGKPSKIPTPQRRSTPTSKVAKGSKR

NT seq 17013 nt +upstreamnt +downstreamnt
atgatcgctgcggcgtttttggtgctgttgaagccgtacagtattcaatgtgtgctgctg
ttattgctgcttttgctcgggactattgcgacaattttgtttttctgctgctggcatcgc
aggcttcgtaatggaaagcatcctatgaaatctgtgctctctggacgctccaagagccga
gttggcctgcgaacacatcattttcgatcagagtgcttcagacacagtccacgtcacgca
agaaggagcctacatgctcgggcaacagaggaaaagcccaatctggttgaggtccctgag
agtgatccagattcatcatcaactctaagaaaacgcaaagtcaagaagagagtcctgccc
gaattttaccagtctgtacaggtcacccctacacgcaaacctagctccagttcggggaac
ccttccctgcactgctccatgtcttcctcggcggatttctcagacgaggatgactacagt
cttaaatctggatcggcatcaccggcacccggggacactttaccctggaacctgcccaga
catgagaggtccaagaggaaaatccagggtggatccgtgctggatccagcggagagagca
gtgctcaggatcgcagatgaaagagacagagtgcagaagaagacgtttacaaaatggata
aatcagcatctgctgaaggtacggaagcatataaatgacctgtatgaagacttgcgagat
ggacataacctgatctcactgctggaggtcttgtctggagacacattgcctcgggagaga
ggaaggatgcgcttccacagactccagaatgtacaaatagcactggattatttaaagagg
cggcaggtcaaacttgtaaatatcaggaatgacgacatcacagatggcaacccaaaactg
accctgggattgatctggaccataatactgcactttcagatctcagagattcacgtgaca
ggggagtccgatgacatgacagccaaggagaggctgctgttctggtcaaagcagataacc
gagggctatgtaggtgtaagatgtgacaacttcacaacctcctggagggatgggaggcta
tttaacgccattattcataaatacaggccagacctggttgacatgagttgcgtgtcgaca
cagaccaaccgatcaaatttagagaacgcgtttggtgtagctgaacaactaggggtggcc
aggctgttagaccccgaggatgtagacgttcagtctcctgatgaaaaatcagtcatcacg
tacgtttcaacactgtatgatgccttccccaaagtacctgaaggtgttgatggaatcagt
gctaatgatgttgatatcaaatgggtggagtaccagaacatgatcaaatacctcagccag
tggatcaaacacaatgtgattgtgatgtcagataggtcattccccaacaaccctgtggaa
ctcaaggcactttatacacaatatctacagtttaaagagcatgaaatcccactgaaagaa
aatgagaagacaaaaatcaaaattctctacaaaatgcttgagatgtggattgagtttgga
cgtattcagttacccccgggtcatcaccctaatgatgtggagaaggaatggggtaaatta
attgtcgccatgctcgaaagagagaagagtctgaggcctgaggttgaaaggcttgagatg
ttgcagcagattgccaacagggtccagcgggactgtgtcaacggggaggacaagctggcg
ttggcaagaacatccctgcagtctgatgcaaaacgccttgagtctggtattcagttccta
aatgaagctgagattgctggctaccttttggagtgtgagaatatcctcagacaacaagtg
gtggacatccaaattcttctggatggaaaattcccctttgcagatcaactcgtccaaagg
gtgtcaaaactgcgggatgaccttctagccctgagagccgagtgttcttctgtgtacaac
caaggtcgcacactgacaacagaacaaaccaaaatgatgatctcaggcatcacacaaagc
ctgaactctggcttctcccagaacattaacactggcctgacaccagcccttacacctgca
ctcacccctggagggttaggtacccctgggtccacattcacctctagccttacaccgtgc
ctgaccccatccttgacccctgctttgacccctggtctacagcctgcttcagtacagact
tacgtggggagcggcggcatagacccagggagcctcaagaatttgaaacacatgcagatc
cgcaaacccttgctgaaatcctcactggcagactccaacatgacagaagaagaggtcaac
atgaaatttgttcaggaccttttgaactgggtggaagacatgcagttgcaactggatcgt
tctgagtggggatcggatttgccaagtgtggaaatgcatttagagaaccacaaaacagta
catagagccattgaagaatttcaaatgagtcttaaagatgccaaactcagtgagattcag
atgaacataccactgaaaataagtttctcagaaaaactgaacaaacttgaaaatcagtat
gaaaggttattgagttgttcaagagagcgacaaagccatctggaaagcctgcacgacttt
gtgtcactggcaactcaggagcttatctggttgaatgagaaggaggaagaagaggttgcc
tttgactggagtgatcgcaacagcaacgtgtccaagaaaaaagagtaccatgctgatctt
atgagggagctggatgaaaaggaggaagtcatcaagtctgtgcaggacaaggctgaacga
ctccttcttaagaaccacccagccaggctaactattgaagcatacaaagctgccatgcag
acacagtggagttggattttacagctctgctcctgtgtagaacagcatcttaaggaaaat
gctgtttattttgagtttttcagcgaagccaaagagtccatggactatcttaagagcctg
caagatgccattcaaaggaagtacagctgtgatcgaacgagcagcctccacagactggag
gatctcatccaggagtccatggatgagaaagagcagcttctgcagtaccgcagcacggta
gccgggttagtgggcaggaccaaaaacattgtgcagctcagacccagaaaccctgacagc
cctgtaagatcctcgatccccgtaaaagccatctgtgattaccgacagattgagataact
atttataaagacgatgagtgcgtactggccaataactcccaccgggccaagtggaaagtc
atcaacccagcagggaatgaggccatggttccctctgtctgttttactgtgcctccaccc
aacaaagaggctgttgatatggctgcaagaattgagcaattataccagaatgtcctggca
ctgtggcaccactcccacatcaacatgaagagcgtggtgtcttggcattatctaatggct
gacatacgagccatccgcaactggaatgtggcctcaattaagaccatgctaccaggtgag
catcagcaagtcttgagcaacctgcattcccactttgatgagttcctggaagacagcgaa
gagtctgaggtattcacagtggcagactgtacccagctagagagagatgttgcggcctgc
aaggaatattaccaggaactactcagatctgcagaaagagaggaacatgaggagtctgtg
tacaataattacatctcagaaatacgcaacttccggatgcatctggaggcccacgaagaa
cacctgatcaggcaaatccgcacaccgctggagagagacgacctagagcagagtctccag
cgcatcacagagcatgagaggaagacagcagagctgaataaactgaaagaagaccttgat
gtcatgaaggagaagtgtgagctgttcctcagacaggctacaggttctccatctgcgccg
accctttcctctgaactcaccgtcctcgttcagagcatgagccaagtgtactccatgtct
tccatttatatggacaaactgaaaacagtgagcttagtggtgaagcacagccagagagca
gaggcattagtgaaggcctacgaatctaaactctacgaggaagacgctatgaactctgac
ctcaagtccattgaaacagtcatttctacactcaagcaatggcggacagagattgatgag
aaccaagaggtattccatgacatggaggatgagctgcagaaagcacgagtcatcagtgac
cgcatgtttaaggcccacaacgagcgtgactttgacctagactggcacaaggagaaggct
gatcaactgaatgagagatggcacaacattcactcccaggttgataacagacttcgggac
ctggatggcatcagcaaatctctgaaacactacagagactcctacagtagtcttgatgaa
tgggttacggaaatggaggcagcacagctaaaggcccaagaaaacaaacctgaagatagc
aaggcactcgctgaactgttaaacaaacagaaggttcttgttgctgaaatagaacaaaaa
cagagcagaatggatgagtgccagaagtactcagagcagtactcatcttccatcaaggat
tatgagcttcagctgatgaccttcagagcgatggttgactcccaacacaaatctcctctc
aagaaaaggaagatgcagagctcctctgatgtcatccagcaggagtttatggatcttcga
actcgctacactgccctcgtgactctcatgactcagtatgtgaagtttgccagtgaaacg
ctgaagagaactgaagaagaggagagatctgttgatgaggagaagagagagcatggtgat
aaagttagcaaactgttgcactggatgtccaatgtgaaacagggccagaacaatgatggg
aatgctctgacagatagtaatgccaacacagacgcttctaataagccccaggtgtcagtt
gaggaaatggtaacaaagaaggaacaaattgcagaagcactgagggccacacagatgatg
ctgaacaaacacagtgaaaaaatgacagaagaggaaagagaaaaggcccaggagcagctg
aaggctctcaatcaagcctacaatgaactctcccagcagtgttcagagcagacgacttct
gcagaagaggctttattggagagacataaggagtttacagagaagttggaggatgtgtgt
gataatctcactctgacagagaaccgtctgattggtcatcagcaacaggctgacagtgca
gggtgcatcacagacctgcagcagtaccagcaggagcatcaggctctgcaaaaagacgta
ttgacaaatgccagtgccttgaatgaggtcatcaccagtactaaaaagtttctggaagaa
aatcggagcaagctgacgccagatcaaattgccatcatcgagagtaagttggaagaggct
aaaagcaaagccaagctcatcaaccagcgggctgaggagtccaggaaagacttggagaag
gttgtaaccacagccataaaacaggagagtgaaaaggcagcagctgttgagcggcttgaa
gaaagcaaaaacaaaattgaaggtcttctggactggatatccaacatcgggaatgaaaac
gagagtggtcttgataaaactgaccatataagcaaagagaatggaaacctgccagaggag
aaatcagccatgggactgatagcagaaaatgacgatgccaatggaaacgctttacagacc
actgaaagtgattttggcaaggagagcgatgggaagaacgacgcctcccttgataagcag
tatgacagagtcaaggctcgtcatcaagaaattttgtcacagcagcaggacctgatcatg
gccacccagtcagcccaggctctgctggacaagcaagcaaacgtgctggctccagaggag
aaggaaaaactgcagaagaacatccaggagctgaaggggcgctatgaagcctctctgaca
caggctgaacagcagatgaagcaggttcagtgtgtccaggaggagctgaagaagttccag
gatgattgtgaggagtttgagggctggttagatcaggcagagagagagatagaggagctt
agggctcctgaagcctccctcaatattctcagtgataaactccagcgacagaagagcttt
tcagaggatgtcatctctcacaaaggggaccttcgcttcatcaccatctcaggtcagaag
gtacttgatgtggctaaaacatgtggattggacgaccctgcaggtaaaaattatccgctg
cacatggatacttcaggaacctgttctgctgtcaaggatcagttggactcagcagctggt
cgatacaaaaaactacattcccagtgcaatcagcttggcaacaacctcaaagatgtggtt
gacaagtacaacaggtatgaagactccaatgctggtcttttgaagtggctcaacagctcc
gaggaggaggccagaaaacagcaatcagaggccatagcagctgacccacaaacactgcag
aaacagctggaggagaccaaggctttgcaaggtcagatgactggacatcagactgctgtt
gacaccctctgtaaaacagcagagtctttgataacatctgaaggagacctgttgagcaac
ccagatgagatccaggagacagtagatgacatagtggagcggtatgacaatctgtctaag
tctgtaagtgatcgaaatgagaaactgcagatcaccctgacacgctctatgagtgttcag
gatggtttggatgaaatgatgggatggatggagggagtggagaacagcgtgaaagagaaa
gaacaaatacccctggactctgcatccattggagatattctcagcaaagaagcagcctta
gagcaggacatagctagccgccatagcagcatctcagccatgaaagccaaagtgaagaag
tttgtggagacggcagatccctctgctgcagcacttctccagtctaagatggatgctctc
tcacagcgcttctctgatgcctgtgacaagcataagcaaaaagtatcacaactggagcag
ctgaaggagaaagtggaactgtttgagaatatcgccgataaagcccaacagtttgttgtg
aagcgttcacaagatctacatgagacagatggaccagggaaaacattcaatgaactgtct
caactaatggagaacactaaagctgagatggctgaacatgccagtgatttggagaagctg
cagaccttgtccaatgagctgtctgaaataagccttgatgggaataaagcccagattcag
agcaagatggacaatcttttgaatatttttaccaccttcaaagacactgtcaaagaaaaa
gaagatgaggtgtcaacctgccaagaccagctgggtgagttcaggtctgcagccagcgcc
ctcaccaagtggctggaggaaaccactgagaaagtacctgtagttcagccaagcagcagt
gagaaaagtctggagaaggacctgcagacagtcactggattattagacgaatggacatcc
aaaggccctgctgtccaagacctgaacagtaaagggtcatcactatgcagcctcatcagt
ttcctcacatcccctgccaaaacaaagacccctaacaagtcagctcttactaatggtggt
ggtccagcgagccattcctacctaaccaataaagagctgatggtaattcagcagaacatg
tcattcatcaacgagggatacacaagcctgggggaaacgttgaagaatcgagcctcagag
cttagtagctcagtgcaagaggtgaaaggggcccaaaaggatgttgacgacatgatggca
tggctgaaggacatgaaaaatactgcagcatcttggaacaatgccgccacagagaaagat
tcagtgaaaacacagctcgagcagcagaaggcatttgaagatgacatgaagcaaaagcaa
gagcagctccagaagctaagagagaagctcctcaacttgattgaaactcatccaaactcc
ccagaggcagcaaagtggaagcagatgctggcagaaatagatgctgcttgggcagatatc
agcggctctgtagaggagaggaagcagcacctggagcagtccaacaagaacctggacatc
ttcaaaaccactgaactgcagcttggccagtggctctcggagaaagagctgatgatgagt
gtgcttggaccactctcgatagacccgaacatgcttaaaatgcaaaagcaacaagttcag
attctacagaatgaattcaagagccgaaaacctcaatatgagcaacttgaagaagctgcc
tctgccattctaagctcctcaggccaccaggcaccctcaaatgggaagctggtgagggag
caactcactgctgtcacccagaagtggcaaggccttacagggcaactggaccagcgagac
agtctcattgaccaggctgtggtgaagacggggcaatttcaggatttactgagaagtctc
agccagaccaccactcagctggagaatcaactcaccaaccatcaggcccacagcacccag
cccgacgctgtaaagaagcagttagaggaagtccagaacatctccgctcagctaagagag
gagaagaagaagctgaaagaggctgaggccatcaatgcagaactcacagcaatggtgact
gaggactatctcaaagcagacttagccagacagctggagagtgtcagcaagcctttcaaa
cagctggaagagaaagcagcaaaacagatcgagcagctgagctccacctttgccagctct
cagcagttccatcagacctccaaagacttccagtcatggctgggtgaaaatctccaggac
cagtctaagcctcaacacatatctgccaaagtggaggtcctgcaacaaaccctggaggag
cacagcaaactccagaaggctcttagtgagcatgaggaggcttataacacaatcatcggg
gaaggggagatgcttctgcagaacactgatggtgcagaaaagctggcactacaggggcag
ctcactaccctctcatctaactggcaggaggtgaagaagaactcagtggaacaggctgac
aaacttcagactgctctgcagagatctcagaagtatcaggagcatgcagagaagctcaac
acctggattcaggagtgtgaagccagtgaagaccgagtcaaactaactgttgatcctgct
gctgtggagagctcaatttctcaggtgaaagctcttcagaaagatattgacaagcacagg
gggatgatggagcagctcaacacagctgcagatagccttttggaggtggccaatattgac
actgaagatataaaagaggagaaggatagcattggcaaaagagtggaaaatgttgaggag
ggtctgcagagcaaaagggaatccctggagaagatctcacatacaattaaggaatttaac
gatgcctacaaagaggcaaagggtcagctagagggggctaagaagcaggtggatgcatat
gaatcacaaggagtgcaggcacacagcaataagaacttaaccaacatgaaagcccaacat
aagagtatggcgggagtgcagaaccaagtcgaacacttgaagaacttagctaaggacctt
gtagtagacgttccagacgctgatggagtcacagacctcttactgcaagctgacagcata
gagacagactacagtaccctcaacgacaaactagagaagacatgccaagtcctggagggt
aaactgcagggtattgggcagttccaaaacaacatccgtgagatgttcagcagattcaca
gatctggatgatgagttggacagcatggctccagtggctcttaacttggctgttcttaag
gagcagcaggacaacattgggagctttcttacaaagctacaagagctgatggccaacaca
gccaacgctggggacagctgcaagaagatgctagagactgaatcttcacctgacctgcta
ggcctgaagagagatctggatactctcagtaagcagtgtggcaaattgatggacagagct
aaaggcaaggagacgcaggtgcagagcactctcaccaaactagaggagctgtatggtaaa
cttcaccaagtggaagataaacttagcggagctgtggaaaaggaggcatcccaggaggcc
gtcggcatggagacagacgtcatcaatcaacaactggaggcctttaaggctttccagaaa
gaggagattgatccattgcagacgcagcttcaggacatcagctccctaggccagggcctg
atccaaaatgctgccaaaggtaccaacactaagaagctggaggatgacctggagaacgtc
aacacaaagtggaataccctcaataaaaagattgctgagcgttcagcccagctgcacgaa
gccctgttgcattgtgggaggttccaggatgctctggagtcactgctcagctggttgact
gacacggaggagctcatggccaatcaaaaacccccctctgcagagttcaaagttgtcaag
gcgcagatacaagagcagaaactcttacagagactgctggatgaccgtaagccgacggtg
gagctgataaaaaaagagggaggaaaggttgcagaactggcagagtctgtggataaggag
aaggttgcaaaagagatcgaatgcctggggcagaggtgggacactctgctcaagaaggct
gaaaacaggcacaagcaactagagagcattttagtggtcactcagcagttccatgagacc
ctggagcccctaagcgagtggctcaccgccacagagaaacacctgtcccactccgaacca
atcggcacagagatatgtaagctggaagatcagatctctcaacataaggccttagaggag
gagattatgaatcacagtaaagacctgcttcaggttgtcagtttgggtcagatgctcaaa
actgtgagctcagtggacaataaggactttgtccagtccaagctggatgccacccaggcc
agttacattgagctccaggagcgctgcaggaggaaagctgagatgctgcagcaagctcgt
gtgaatgcccagctgtttggagaggatgaagtggctctcatgaactggctcaacgaggcg
cacacgcagctggatgaagtgtccgtggaggactacaaaatagacgttcttgaaaatcag
ctggcagaacaacggactctacaaagtgatattgagctgaggaagaagaatgttgaccaa
gccatcgctaacgggatggagctactgaagcaaacaacaggtgatgaggtggttgttatc
caaggcaaactggatggaataaaaacaaagtatgctgagatcaattctatgagtaacaac
gttttgaagacactggagcaggttttgagtctctcctcaaagctacagcattcccacgag
gacttgagatcctggctagagaaagcagaagctgagattcatgcatttgctgatcaggag
ccactcggggaccagctcattcatgcacaaaacaagcagaaggccttgttgaaggagacc
aaagatcaaaaacctgcgattgacaagctgaatgaggtcagcagttctctccttgatctg
atcccctggcatgctcgtgagggtctggacaagctagtgacagaggataatgagcggtac
agagccgtctgtgactctatcacccagcaggtcgaccagatcaacgccaacatactcaag
tcacagcagtttgaacaagctgcagatactgaactggcttggctgactgatgctgagagg
aagttgctgtcggtgggcgagatcaggctggagcaggatcaaaccacagcccaactccaa
gcacagaagatcttctctatggacatcatgaggcacaaagatgctgtggacgaaatcgtg
aaaacaggaaaggccatcatgaacatcaaaaacccagaagaaaaagaagttgtgaaggcc
aagacccagactctcttggagaagtatggtgtcgtcagtcaactgaactcagaacgctgt
ctgcagctggagcgcgcccagtctctggcaagccagttctgggagacctatgaagagttg
tcaccatggcttcaagaaatcttaaacaccttcagccagctgcccccacctgccattgag
tatgagacactcagacagcagcaggaggagctacggcaaatgcgagagctgattgctgag
cacaagccacacattgacaagatgaataagaccgggcctcagttactggaactgagccca
gtggagggagtgcccatcagagagaagtacacagttgctgaccagctttacacccaactg
aaggctgatgtcaaggagagagctgcaacactggatgaagccatctccaaatccactcag
ttccatgataaaattgacccgatgctggaatcactggagcggattgccgagcgccttcac
cagcctccttccatctcagttgaagtggacaagatcaaggagcagattactgaaaataaa
tccgttactgtggacttagaaaagctgcaaccttcttacgagatgctgaggcagcgaggc
gaagagatgattgcacgatctgaaggtgcagacaaggacatatctgccaaagctgtccaa
gacaaaatggaccagatggttttcctctggaacgacatccaggccttgctggaggagcgg
gaggccaagctgctggatgtgatggacctggccgacaagttctggtgcgaccactgcgct
ctgatcgccaccatcaaagacagccaggatctgctgagggagctggaggagcctggagtc
gatccttcagtggtcaaacagcagcaagagtttgtggagagttttaaagaggagattgat
gggcttcaggaggagcttgacacagttcgaaaccaaggagaggagctcatgactgcctgt
ggagaacctgataaacctgtgataaagaaaagccttgatgaggtgaactcagcgtgggaa
aatctcaataagacgtggaaggagagggtagagagactggaagaagccatgcaggctgct
gtgcagttccaagacggcctgcagggtatgtttgactgggtggatattctggagggcaaa
ctggattcaatgtcacctgtaggtacagacctggaaactgtcaagcagcagattgtcgaa
ctcaaggagtacaaaggagagtcataccagctccagatcgagatggagcgtctgaaccac
caggcaggcctcctgctgaagaaggtgacggaggatgccgatcgttgcgccattcaggag
cccatgtctgagctcaagatgctgtggaacaacctggatgaaaagatcatcagccgacag
cacaaactggagggaggcctcctggctctgggccagttccagcacgcattggatgaactg
ctggcatggatgagccacactgaggagctgctcaatgagcagaggaagactggaggagac
cctaaagccatcgagatagaactcgccaaacacaatgttctccaaattgatgtgctggct
cataaaacgacagttgagactgtgaacaaagcaggtaatgaactggtggaatccagcgct
ggagaggaagcctcagctctgcagagcaaactggaaaacctgaaccagcggtggaaagcc
atccaggagaaggcagcgcagaggaagcaacagctggaaagcgctctgattcaggcccaa
ggtttccatggtgagatagaagatatgcagcaatggctgaaagacacagaacgtcagctg
ttggcatcaaaggctgtgggaggcttaccagacacggcccgggagcagcttaacgcccat
ctggagttgtgttctgccttcgaggtgaaggaggagctgtatcaggagctgatgaacaag
ggtcagcaggtgctcatcttgatgcctgagggtcctgacagcaacacagagcaggacctt
accaacctgaaggagaaatgggaaacagtacaggcgaaggtcgctgaaagaaaggggaaa
ctagaagaagccttgacactggccacagatttccacaactctctgcaggacttcattaac
tggttaacccaagcggagcagacgctcaacatggtttcccctgcttccctcatactggag
accatcatgtttcagattgatgagcataagatgttcgtgacggaggtgaactcccacagg
gatcacatcattgaactggacaagactggcacacatttgaagtatttcagccagaaacag
gatgtggtgctgatcaagaacctgctgctcagcgtgcaaagccgctgggagaagctggtg
cagcggtccgttgagcgaggtcgtctgctggatgatgccaggaagagggcaaaacagttc
catgaatcttggagtaaactgatggaatggttggaagagtctgagaagagtctggactcg
gaggtggaaattgccaacgatccagacaagatcaagacgcagctctctcagcacaaggag
ttccaaaaagctctgggaagcaaacactcagtgtatgacaccaccgttcgaacagggagg
gccctgaaagacaagacctctcttcaggatgataagcagaagctggacgacatgctgagc
gaactgagggacaagtgggacactgtctgtggcaagtcaatagagaggcaaaataagctt
gaggaggccctgctgttctccggccagtttacagatgctctccaggctctcattgactgg
ctttacagagtggaacctcagcttgctgaggaccagccggtacatggagacatagacctg
gttctcaacctcatagacaaccacaaggttttccagaaggagctgggaaagaggacagtc
agcgttcaagctctaaaacgctcagccaaggagctgattgagagcagtcatgatgactcc
tcctgggtcaaagtccagatgcaggagctgagcactcgctgggagacggtgtgcaacctt
tcagtttccaagcaggctcggctcgagcaggccctgtgtcaggctgaagagtttcactct
acagttcacatcctgctggagtggctggctgaggcagagcagattttgcgtttccatggc
agcctgcctgatgatgaggaggctctgcgagcacttatcgaccaacataaggagttcatt
aagaaactggaggaaaagcgagtggctcttaataaagcgaccagtttgggggaggctatt
ctgaccatctgccatccagactctatcacaaccatcaaacactggaacaccatcattaaa
gcccggtttgaagaggtgcaagcctgggccaggcagcaccagcagcgactggcaacggcc
ctaggtgagctgttagccactcaggaactgctggagaatctgctgacctggctacagtgg
gccgagtccaacctcaatgataaggacaaggagataattccgcaggagattgaggaggtc
aaaagcctcatagctgagcaccaggcattcatggaggaaatgaccaggaagcaaccagat
gttgacaaaatcacaaagacacacaaaaggaaggctgcattggaaccccaaatccagtct
cagatccctgtgctcgacaaaggaagagctggaagaaaacgttctcccacacaaacaatg
tacgcgtcagcaacacaacctcccattgaaaccaagaacccccgggtcaacctgcttgtc
actaagtggcagcacgtgtggctgctggctctggacagaaggaggaaactcaatgatgct
ttggacagattggaggagctgaaagaatttgccaactttgactttgatgtgtggcggaag
cgctacatgcgctggatgaaccataaaaagtctcgtgtcatggacttcttccgccgcatc
gacaaagatcaggatggcaaggtgacccgacaagagttcatagagggcattctctcttcc
aaattcccaaccagtcgtctggagatgagtgctgtggcagacatatttgacagggacggt
gatggctacatcgattactatgagtttgttgcagctcttcatcccaacaaggacgcttac
aaaccattaacagatgcagacaaaattgaagatgaggtaacacgtcaagtggcaaaatgc
aaatgtccaaaacgattccaagtggagcaaataggtgccaacaaataccggttctacctt
ggaaaccagtttggggactctcaacagcttcgccttgtacgcattttacgcagcaccgtg
atggtgcgggtaggaggaggctggatggctctggatgagttcctggtgaagaacgacccc
tgtcgagctaaaggcaggaccaacatggagctgcgagagaagttcatcctcccagaaggc
accactcaggtgatggccagcttccgctacagaggccgcagatctcggccgtcgtctaga
ggagcgtctcccaacagatccacctccagtcagagctgtgccatcccatcagccccagcg
gtgaccagcacccccaagacaacccaacacataacccgcaattatgataagccatggctt
acaaacagcaaaccctccactcctcttaaatcatccgactcctttgggagccaaggttca
tcctcagagggtactccagttcaaggcagcaaattgcgtcttcctggatatttgtcagga
aaaggctttcagtcgggtgaggagggaacgttgatcagcgctgccgtgctcaaggctcga
ggacagacaataggtgaatcgaggagaaactcaagccgacctggaagtaaagctggcagc
cgagggagtagccgcaggggaagcgacgcctctgacttcgacatctcagacatccagtct
gtgtgctcagacatgtccgaaacggtcggtgactccagccgagccacgccgcgctccgca
tcccgccaacaaagaggaaaaccctccaagatccccactcctcagagaagaagcactccc
acgagcaaagtggccaagggatccaagcgatag

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