Syngnathus scovelli (Gulf pipefish): 125980697 Help Entry 125980697         CDS       T08785                                  Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism sscv  Syngnathus scovelli (Gulf pipefish) Pathway sscv04020   Calcium signaling pathway sscv04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sscv00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     125980697    04020 Calcium signaling pathway     125980697  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sscv04040]     125980697 Ion channels [BR:sscv04040]  Voltage-gated cation channels   Ryanodine receptor    125980697 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_6 Ago_Mid Motif Other DBs NCBI-GeneID:  125980697 NCBI-ProteinID:  XP_049596076 LinkDB All DBs Position 14:8949608..9005182 Genome browser AA seq 4887 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVACIQKENRKFCLAAEGLGNRLCYLEPTSEAKYVPP DLCICTFVLEQSLSVRALQEMLAKSGQNNEARLIRKAAQSGGHKTLLYGHAILLRHSFSS MYLACLKTSRSQTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVS SERYLHLSISNGNIQVDASFMQTLWNVHPICSGSNIEEGYLLGGHVMRLFHGHDEVVTIP GSDQSEEQQRIVNYEIGKAGAKARSLWRLEPLRISWSGSHIRWGQPFRLRHLTTGHYLAL TEDRGLVLQDRERSDTISTAFCFRASKEKLEQSPKRDIEGMGVAEIKYGDSLSFIMHVAT GLWLSYQAPDVKSARLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRNTTLLFNR FIRDLDCLGLKNKTLVALPIEEVLQTLNDLITYFLLPDAELEHEERQIKLRSLKNRQNLF KQEGMLTLVSNCIDRLNVYNSVAHFGECAGPEAGAAWKDILNLLYELLAALIRGNRINCT QFSNNLDWLVSKLERLESSSGILEVLHCILIESPEALNMIQRGHIKSIISLLYKHGRNHK ILDVLCSLCVCNGVAVRTNQNLICDHLLPKRDLLLQTQLVNDVQSMRPNIFLGVSEGSAQ YKKWYYELMIDQVDHFVTSEPSHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYGFDG LHLWSGRIPRAVASLHQHILTSEDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFF PVVSFSAGVKVRFLLGGRHGDFKFLPPSSYAPCYEALLPKERLRVEPVKEYKRDVDGVRD LLGTTLILSQASFIPTPVETGQIVMPPHLEKVRDKLAENIHELWGMNKIELGWSYGKIRD DNKRQHPCLVDFSKLPETEKNYNLQTSTETLKTLLALGCRVVQVNSNADESLKKIKLPKN FMMSSGYKPSPLDLSDMKLTPGQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSKRN PRLVPYALLDERTKKSNRDSLREAIRTLIGYGYNVEPSDQEGGQTVERLSIDKIRFFRVE RTYAVKTGKWYFEFEAVTGGDMRVGWARPGCKPDVELGTDQLAFVFDGFRGHCLNMGGRL FGRCWHSGDVVGCMINMEDKSMIFTLNGEILITTKGSELCFTDFETEDGFIPVCSLGLAQ VGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNRELTMWFSKRLPTFVNVPKEHNHIAVT RIDGTVDSPPCLKVTHKTFGTQNSNTDMVFCRLSMPVEFHSFFKISPVIDVNGVHEDDTL KVKHRYPLRSVRHSDESRRVDYSSITTYYHSVRVFAGQDPSCVWVGWVTPDYHYYSNNFA LSKTRTVTVTLGDERGRVHESVKRSNCYMVWGGDVTNATHASSRSNVDLEIGCLSDLATG LVTFTVNGKEISTSYQVEPNTKLFPAVFVQPTSPNLFQFELAKIKNAMPLSSAIFKSEHK NPVPQCPPRLDVQTINAVLWSRMPNTFLKVETARVSERHGWSVQCVEPLQMMAVHIPEEN RCVDIMELSEQEDMREFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSG MLREGFYNLLISIHLETAKGARLTMKDEFIIPVTTETRSIRLFSNASKKHSPPGVGLSTS LKPRLNFAPPCFINTKREHHLYSPQIPLDALKEKSISMLTEAVQGGGHYIRDPVGGGVEY QFVPILKLISTLLTMGVLCSEDVHKILLLIDPNVFKDAHDEGPTSTTDKEGLTGNEEKAV EAGEEEAAKEAKQSIKGLLETRLPEPVKRQMCELLHYFCDCELKHRIEAIVSFSDKFVSK LQYNQKFRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLTFSTGDDCPCPSAIQGEL YDFHNQLQLHCGIPMEEDEDEQDTSIKGRLLTLVNKIKGQAHKMEQPLQKEQAAPSNLKE LISQTMVSWAQECHIQDPELVRKMFSLLRRQYDSIGELLRAMRKTYTISAASVHDTIRLL ASLGQIRSLLSVRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRILGMHETVMEVMVNVLG GDKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPL DVAASSVMDNNGLALALEEPDLDKVVTYLAGCGLQSCPMLLAKGYPDIGWNPIEGERYLS FLRFAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISETPALD LPGSVQGVSCDVSADGDDEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRI RAILRSLVPTEDLVGIISIPLKTPIVNKDGSVTEPDMSACFCPDHKSPMVLFLDRVYGIE DQSFLLHLLEVGFLPDLRAANSLDTEGLCTTETALAMNRYIGSAMLPLLTRCAPLFAGTE HHAALIDSTLHTIYRLSKGRSLTKAQRDAIEECLLAVCKHLRPSMLQQLLHRLVFDVPLL TEYCKMPLRLLTNHYEQNWKYYCLPSGWGSYGTASEDELQLTKKIFWGVFDSLSQRKYDP ELFKMAMPCLSAIAGALPPDYVDSAIVGEIVSVNTHGNFEPKPITTANIALPEKLEHFVN KYAEHSHEKWSAEKVLLGWKYGDCVDEKARIHPQLRTYKALTEKEKDIYRWPIRESLKSM LAMGWSIDRARDGESMSHQRENEKVRKISQVSQANGFNPSPLDTSNVILSRELQGMVEVV AENYHNIWAKRKKSDLGSRGGATHPLLVPYETLTAKEKARDREKAQDLFRFLQISGYHIT RGLRDLDQDSSSMEKRFAYRFLRKLLKYVDSAQEFISHLEAMAASGKTDRSPHEQEIKFF AKVLLPLIDQYFKNHSLYFLSSPNQNLSSSGYASNKEKEMVTSLFCKLAALVRHRISLFG SDSTTMVSCLHILAHTLDTRTVMKSGSELVRVGLRTFFENAAEDLERTFENLKLGKFTHS RSQMKGVSQNINYTTVALLPILTALFEHITQHHFGIDLLLDDVQVSCYRILTSLYALGTG KNIYVERQLPALGHCLATLAGAMPVAFLEPMLNIYNPFSVFATKSGRERAILGIPDSVEQ MCPGMPRLDGLIKDINDMAESGARYTEMPHVIEVVLPMLCNYLSYWWERGPENQPAGGSS TCSTVTSEHLSLILGNILKILNNNLGIDEASWMKRIAVYVQPIISKARTILLKSHFLPTL EKLKKKTVKVVAEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSR WLKEPDADSNELFKMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDNKTKMSKSF KEKSGGQDQERKHKKRRGEFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYLL RDTDDEVKDHIRQNLHLREKSEDPAVRWQLNLYKDIMVRGEGAPDPERVVDRIQRISAAV FNLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLLAYQRIWIE TEEYSFEEKLVQDLAKIHHKVEEEEEEEIRKQPDPLHQLVLHFSHNALTECSSLEDDPLY IAYADMMAKSCAEGEEENDEKEKTFEEKEMEKQKMLYQQARLHDRGAAEMVLQMIGASKG RLDAMVTFTLKLGISILNGGNILVQQKMLDYLKEKRDVGFFKSLSGLMMSCSVLDLNAFE RQNKAEGLGMVTEEGSINVSERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTG NTTTVNIIISTVDYLLRLQESISDFYWYYSGKDIIDEAGQRNFSKALAVAKQVFNSLTEY IQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQKDMIVMML SLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDSFKIYDAECKGFI SKKDFQKSMENQKQYSQSEIEFLLSCAEADENDMFNYVQFVERFHEPAKDIGFNVAVLLT NLSEHMPHDARLSTFQDLAESVLSYFEPYLGRIEIMGGAKRIERVYFDISESSRTQWEKP QVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQISEPDPVERQEEEDEDDS QSLAENQEEEEEQNLMLESSSAFTIACISMRKNICHVRQMLTFKSMKRQYRKFRKMSVRE TVHGFFAFFWMIITGLFHFVYSLVWGFFHILWTTMFGGGLVEGAKNMKVTDILGNMPDPT QFGIHGDVLETDKMEAHEASALTEMGHMAQGEVAEGDLMAELLNIQPKKEGKHGAEPGLG DVSEVVVGGDAPSIASAVKQKKAQMAAKNRASNGDYKSDSEKADSDDGEKKDHDKAKDEA PPALPLEKKTPKKRLDVKKDPPEAFMASFFAGLEIYQTKMLNYLARNFYNLRFLALFVAF AINFILLFYKVTGDNSDDEDPWNGHGRTVEEEEEDNSLEYFILQESTGYMAPTLRCLAIL HTIISFLCVVGYYYLKVPLVVFKREKEIARKLEFAGLYITEQPSDDDIKGQWDRMVINTP SFPNNYWDKFVKRKVIKKYGDLYGAERIAELLGLDKSALDFNPTEEAVTKEASLVSWLSS IDTMYHIWKMGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSV THNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVG VRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQV KEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYV WKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14664 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggagaaggagaggatgagattcagttcctcagaactgatgatgaagtg gtgctccagtgcgtggcttgcatccagaaggagaatcgaaagttttgcctggcagctgag gggctgggcaaccggctgtgttacctggaaccaacgtccgaggcaaagtacgtccctcca gacctatgcatctgtaccttcgtgctggaacagtccctctcagtccgggccctccaagag atgctggctaaaagtggacagaacaatgaagcgaggctgataagaaaggcagcgcagagt ggtgggcacaagactctactgtacggacatgccatcctcctacgacactctttcagttcc atgtacctggcttgtttgaagacatcaaggtcacaaaccgataagttatcatttgatgtc ggcctacaggaagattcaacaggtgaggcttgttggtggacaatccacccggcctccaag cagagatcagaaggagagaaggtgcgcataggcgacgacctcatccttgtcagcgtgtcc tctgaacgctatcttcatttatcaatctctaatggcaacatccaggtggacgcatccttc atgcagacgttgtggaacgtccatcccatctgttctggcagcaacatagaggaaggctat ttattgggtggtcatgtgatgcggctgtttcatgggcatgatgaggtggtgaccatcccg gggtcagaccagagtgaagagcagcaaaggatagtcaactatgagataggtaaagctggt gctaaggccagatccttatggaggttggagccactccggatcagctggagtgggagccac atccgctggggtcagccgttccggttgcgacacctgactactggtcactacctagccctg accgaggacaggggcttggtgctgcaggaccgagagaggtccgacacaatctcaactgcc ttctgcttcagagcatctaaggagaagcttgagcagagtccaaaacgggacattgagggg atgggtgtagcagagattaaatatggagactcgctcagcttcataatgcacgtggctacg ggactgtggctttcctaccaggcacctgatgtcaaatctgcacgtttgggtcctctcaag agacgagcatgtctacattccgaaggtcacatggatgacggcttgacactgcaacgctgt caacatgaggaatctcgagccgcccggatcatccggaacaccactctcctctttaacaga ttcatcagggatctggattgtctgggtttgaagaacaagacacttgtggcacttccaatt gaagaggtgctccaaacccttaacgacctcatcacctacttcctgctccctgatgctgag ttggagcatgaagagaggcagatcaagctacggtccctcaaaaacaggcagaatcttttc aaacaggaaggcatgctgacactggtgtccaactgcatagaccgtctgaacgtttacaac agtgtggcccactttggggagtgtgctgggccagaggccggagcagcctggaaagacatc ctcaacctgctctacgagttgttggcagcgttaatcagaggaaacaggatcaactgcact cagttttccaacaacttggattggcttgttagcaagctagagagactcgagtcttcttcg ggcattcttgaagttctccactgtatactaattgagagtccagaggctctcaacatgatc cagagaggacacatcaagtccatcatatcgctgttatacaaacatggacgtaaccacaag attctcgatgtgctttgctcgttgtgtgtgtgtaatggtgtggctgtgcgaaccaatcaa aacctcatttgtgatcacttgctgcccaagagagacctgctgctacaaactcagctggtc aatgacgtccaaagtatgagaccgaacatcttcctcggggtgagcgagggctcagctcag tacaaaaagtggtactacgagctgatgattgaccaggtggaccactttgtgaccagtgaa ccatctcaccttcgagtgggctgggctaacaccaagggctacgcaccttacccaggaggg ggtgaaggttgggggggcaatggtgtaggagatgacctctattcttatggttttgacgga ctgcacctctggtcaggacgcatcccccgggcagttgcatctctccatcagcatatcttg acgtcagaggatgtggtgagctgttgcctcgacctcggagctccaagcatctctttccgc atcaacggacagccagttcagggcatgtttgaaaacttcaatacagacggactcttcttt cccgtcgtcagcttctctgcaggtgtaaaggtaaggttcctgttgggtggtcgtcatggc gactttaaattcctgccgccatcgagctacgccccctgttacgaggctctgctgcccaaa gagaggctgagagtggagccggtgaaagagtacaagagggatgtggacggggtccgagat ttactcgggaccaccctcatcttgtcacaggcctctttcattcccacacccgtggaaacc ggccagattgttatgccgcctcacttggagaaagttcgggacaagctagcagagaatatc catgaattgtggggcatgaataaaattgaattgggctggtcctacggcaagattagggat gataataagcggcagcatccatgtctggtggatttctccaagctgcctgaaacggaaaag aactacaacctgcagacgtcgacagaaactctcaaaaccctgctggcactgggctgtcga gtagttcaggtcaactcaaatgctgatgaatcacttaagaagattaaactcccaaagaac ttcatgatgtccagtggttacaagccgtcccctctggacttgtctgatatgaaactgact cctggtcaggagttgctggtggacaaactggcggagaatgcacacaatgtgtgggccaaa gaccgcatcaagcagggttggacgtatggtattcagcaggatctgaaaagtaaacgtaac cctcgcctggtcccttacgccctgctggatgagcgcaccaagaagtcaaaccgtgatagt ttacgcgaggctattcggactctgattggttatgggtacaacgtggagccatccgatcaa gaaggcggacaaacagtagagcgtctaagcattgacaaaatccgattcttccgagtagaa cggacatacgcggtgaagactgggaaatggtactttgaatttgaggccgtcacaggaggt gacatgagagttggctgggcaagacctgggtgtaaacctgacgtggagctcggcacggat caactggcttttgtctttgacggattcaggggccactgtctaaatatgggtggccgtttg tttggacgctgctggcacagtggcgatgtggtcgggtgtatgatcaacatggaagacaaa tccatgatctttactctcaatggagagatacttatcaccaccaaaggttctgaactttgc ttcaccgactttgaaacggaggatggattcatcccagtgtgcagcctgggtttagctcag gtcggccgtatgaatctcgggaaagatgccagcacctttaagtattacaccatgtgcggc cttcaagagggatttgagcccttcgctgttaacatgaaccgagagctcaccatgtggttc agcaaacgtctgccaacgtttgtcaatgtgccaaaggagcacaatcacatcgcggtgacg agaattgacgggacggtcgacagcccgccgtgtctcaaggttactcacaagacatttggc acccagaacagcaacacggacatggttttttgtcgtctgagtatgcctgtggagtttcac tccttcttcaagatcagtccggttatcgacgtgaacggagtgcacgaagacgacaccctc aaagtcaaacacagatacccactgcgatctgtgcgacacagtgacgaaagtagacgagtg gactacagcagcatcacaacgtactaccactcggtgagggtctttgccggtcaggaccct tcttgtgtttgggtcggctgggttacccctgactaccattattacagcaacaactttgcc ctcagcaagacccgaactgtgaccgtgaccttaggtgatgagcgagggcgagtccatgag agcgtcaagaggagtaactgctacatggtgtggggtggcgatgtgactaacgctactcat gcttcaagtcggagtaatgttgacctggaaattggctgtctcagtgacctcgccactggc ctggtgaccttcacggtcaacggcaaggagatatccacatcctatcaggtggaaccaaac accaagcttttccctgctgtctttgtgcaaccaaccagtcctaacctctttcagtttgaa ctggccaaaattaagaacgccatgccgctgtcgtcagccatttttaagagcgaacataag aacccggtgcctcagtgtccccctcgccttgacgtccagactatcaatgcggttctgtgg agccgcatgccaaataccttcttgaaagtagaaacagcaagggtcagcgagagacacggt tggtcggttcagtgtgtggagcctctgcagatgatggcagttcacattcctgaggagaac aggtgtgtggacatcatggaactgtccgagcaggaggacatgcgggagttccactaccac accttaaagctctactgtgccctctgcgctttgggtaacacccgtgtggcccacgccctc tgcagtcacctggaccaatcccagctcttatacaccatagacaaccaatacctatctggc atgttacgagaaggtttttacaatcttctcatcagtatccatctggagacagccaaaggc gctcgactcacgatgaaagatgaattcatcatcccggtcacaacagagacacgttccatc cgtttgttctccaatgcttccaaaaaacactcgccaccaggggtggggctgagtacctcg ctcaaacctcgcctcaactttgctcctccttgcttcatcaacaccaaacgggagcatcat ctgtacagtccccagatccctctggatgcattaaaagaaaaatccatttcaatgttgacc gaggcggtccaaggtggtggtcattatatccgtgatcctgtcggaggaggtgtagagtat caatttgtgccaatcttgaagctcatcagcactttgctgaccatgggggtcctctgcagc gaggatgttcacaaaatcttacttctcattgacccgaatgtatttaaggatgcacacgac gaaggacccactagtacgactgacaaagaaggactaacagggaatgaggagaaagcagtg gaagcaggagaagaagaggcagccaaagaagccaaacagtcaataaaaggacttctggag acaaggctgcctgaacctgtgaaacgtcagatgtgtgagctactccactacttctgcgac tgtgagctcaaacaccgtatcgaagccattgtgtccttctcggacaagtttgtctccaag ctacagtataaccaaaaattcagatacaacgagctgatgctcgcccttaatatgtccgcc gccgtgacggcaaagaagactaaggagttccgctcgccccctcaagaacagatcaacatg ctgctgaccttcagcactggcgatgactgtccatgtccatcagctatccagggggagctt tatgattttcacaaccagctgcagctacactgtggaatcccgatggaggaagacgaggat gagcaggacacatccattaaaggccggcttctaactctggtgaataaaatcaaaggacaa gctcataaaatggagcaaccgttgcagaaggaacaagctgcaccgtccaacctgaaggaa ctgatctcgcagaccatggtcagctgggcccaggagtgtcacatccaagacccagagctg gtacggaagatgttcagcctgctgaggaggcagtacgacagcatcggcgagctgctcagg gccatgagaaagacttacaccattagcgccgcctcggtccatgacaccattaggctcttg gcttctctgggtcagatcagatctctgctttctgttcggatggggaaagaggaggaaaag ctcatgatcgatggacttggtgacatcatgaataataaggtgttctatcagcatcccaat ctaatgagaattctgggcatgcatgagactgtcatggaggtcatggtcaatgtgctcgga ggggacaaatcacaggaaatagccttccccaagatggtggctagctgttgtcgcttcctg tgttatttttgccgcatcagccgtcagaaccagaaagcaatgtttgaccacctgagttac cttctggaaaatagcagcgtggggctcgcttcaccagctatgaggggctccacacctctc gatgtggctgcttcctcagttatggacaacaacggtctggctctcgcactggaggaacct gatctggacaaggtggtgacctatttggccggctgcggtctccagagttgtccaatgctt ctggctaaaggttatccagatattggctggaatccaatcgaaggagaacgttacctctcc ttcttgcgctttgccgtctttgttaacggtgaaagtgtggaggagaactccagtgtggtg gtcaaactgctcatccgtcgcccggagtgtttcggacctgcactgagaggggagggaggc aacggactgctggccgccatgaaagaagccatcaagatttccgaaacgccggctttggat ctacctggttctgtgcagggagtcagctgtgatgtatccgctgatggcgatgatgaagag gaagtggttcacatgggcaatgccatcatgtccttctactcagcactcattgacctgctg ggacgttgtgccccagaaatgcatctcatcaacaaagggaaaggcgaagctctccgtatt cgtgccattttgcgttccctggtgcccactgaagacctggtgggaatcatcagcatacct ctcaaaacacctatcgttaataaagatggctcagtgacagaacctgatatgtcagcctgc ttttgtccggaccacaagtcccccatggtgctgttcctggaccgagtgtatgggattgag gaccagagctttttgcttcaccttcttgaagttggcttccttcctgacttgagggctgca aactcactagatacagagggtctgtgcaccaccgagacagctttggccatgaaccgttat atcggctcagccatgctccccctcctcacccgctgcgctcccctctttgccggcaccgaa caccacgccgcgctcatcgattccaccctgcacaccatctaccgcctctccaagggtcgc tccctcaccaaagcccagagagatgccattgaggagtgcctgctagctgtctgcaagcac cttcgcccttcaatgctgcagcagcttctgcatcgcctcgtctttgacgtacccttgctg actgaatactgcaagatgcctctcaggctgctaaccaatcattatgagcaaaactggaag tactactgccttccatcaggctggggcagctacggcacagcctcggaggatgaactccag ctcaccaagaagatcttctggggagtgtttgattcattatcccagaggaaatatgatcca gagctgttcaagatggcaatgccctgcctcagcgccatcgctggagctttgccgcctgat tatgtggattccgccattgttggggaaatagtttcagtaaatactcatggcaactttgaa cccaaacctatcacaactgcaaacattgccctcccagagaagcttgaacactttgtcaac aagtacgcagaacattctcacgagaaatggtcagcggagaaggtgctacttggttggaaa tatggagactgtgtggatgagaaggcgagaattcacccacagctgaggacatacaaagct ctgacagagaaggagaaagacatttacagatggccaatcagggagtcattgaaaagtatg ctggcaatgggctggagcattgaccgggccagagacggagagagcatgtctcatcagagg gagaatgaaaaagtacgaaagatatctcaggtctcacaggcaaacggttttaatcccagt ccattagacacaagcaatgtgatcttatccagagagttgcaagggatggtggaggtggtg gctgaaaattaccataacatctgggccaaaagaaaaaaaagtgaccttggaagtagaggc ggagctactcaccctttgctggtgccgtatgagacgctgacagccaaggagaaggctcgt gatcgagaaaaggctcaggatctcttccggttcctccagatcagtggttaccatatcaca agaggtctgagggacttggatcaggactcctcctccatggagaaaaggtttgcttacagg ttcctcaggaagctactcaagtatgttgactccgcccaggaattcatctctcacctcgag gccatggctgccagcggtaaaacagacaggtcacctcatgagcaagaaatcaagtttttt gccaaagttctcctcccgctcattgatcaatacttcaagaatcactccctctacttccta tcatcacccaaccagaacctgagcagcagcggctatgcctccaacaaggagaaagaaatg gtcaccagcttattttgtaaactggcagctcttgtcagacataggatctctctctttgga agtgactcgaccaccatggtgagctgcttgcacatcctggcacacacgctggataccagg acggtgatgaagtcaggttccgaattggtgagggtcgggctcaggacgttctttgagaat gccgctgaggacctggagaggacgttcgagaacctgaaactggggaagttcactcattcg cgctcccagatgaaaggcgtatcgcagaacatcaactacaccacggtggctcttctccca attctgaccgctttgttcgagcacatcacgcaacatcactttggcatagacctgcttttg gatgatgtccaagtgtcctgctatcggatcctgaccagcctctacgctctgggcaccggt aaaaacatctacgtagaaagacagctgccagcgctcggccattgtctggccaccctggcg ggggccatgccggtggctttcctggagccgatgctcaacatatacaaccccttctcagtc tttgccaccaagagtggccgtgaacgagccatcctcggcattccggactcagttgaacaa atgtgtcccgggatgccccggctggacgggctcataaaggatatcaacgacatggctgaa tctggagcgcggtacactgagatgccccatgtgattgaggtggtcttgcccatgctttgt aactacctctcctactggtgggagagggggcccgagaaccagccagctggtggtagcagc acgtgctccaccgtcacctcagagcacctcagcctcattctgggcaacatcctgaaaatc ctcaacaacaatctgggcattgatgaggcctcgtggatgaaaagaattgcagtgtacgtg cagcccatcattagcaaagctcgcactatcttgctaaagagtcacttcctgcccacgttg gagaagctgaagaagaagacggtgaaggttgtggcagaggaggagctgttgaaggcagac agcaagggagacacacaggaggccgaattgctcatcctggatgagtttgccgtgctctgc cgggatctttatgccttttacccaatgctcatacgctatgtggacaacaacaggtccaga tggctgaaagaaccggatgctgactcaaatgagcttttcaagatggttgctgagattttt atcctctggtgcaagtcacataatttcaagcgagaagagcagaactttgtggtccagaat gaaatcaacaacctctccttcttgactggagacaataaaaccaagatgtcaaagtccttt aaggaaaagtctgggggacaagaccaggagagaaaacacaaaaaaagacgcggtgagttc tactccatccagacatcactgatcgtagctgctctcaagaagatgcttccaatcggcctc aacatgtgcaccccgggggaccaggagctcatctcattggccaagacgcgctatcttctg agggacacagacgacgaggtgaaagatcacattcggcaaaatcttcacctcagagaaaag tcggaagaccccgctgtgaggtggcagttaaacctttacaaagatataatggttcgaggc gagggggccccggaccccgagagggtggtggatcgtattcagaggatctccgctgctgtt tttaacttggaacaggtggagcaaccactaagatccaagaaatgtgtctggcagaagttg ctgtccaagcagcggaaaagagcagtcgtagcctgtttccgaatggctccactttataat ctgccgaggcatcgctctattaatctcttccttctggcctatcagagaatatggatagaa acagaagagtattcttttgaggagaagctagtacaggatcttgcaaaaatacatcacaaa gtggaagaggaggaagaggaggagattagaaagcagcccgatccgcttcaccagctcgtt ctgcatttcagccataatgctctcacagagtgcagttccttggaagatgatcctttatat atcgcatacgcagatatgatggcaaagagttgtgctgaaggtgaagaggaaaatgacgag aaagagaaaacttttgaggaaaaggaaatggagaagcaaaagatgttgtaccagcaagcc cgactgcatgatcgcggggctgcagagatggttctccagatgattggtgctagtaaaggt cgtctggatgcgatggtaaccttcaccctgaaattgggcatctccattctgaatggcgga aacattctggtgcagcagaaaatgttggactacctgaaagagaagcgagatgtcggcttc ttcaaaagcttatctggactaatgatgtcttgcagtgtgctggacctcaatgctttcgag agacaaaacaaagcagaaggtcttgggatggttacagaggaaggatcaatcaacgtgagt gagcggggttccaaagtgcttcaaaatgatgagttcactaaggatctttttaggtttctg cagcttctgtgtgagggacacaacaacgatttccagaactttctaaggacacagacagga aacacaactacagtgaacatcattattagtactgtggactatctacttagacttcaggaa tccatcagtgatttctactggtactactccggaaaagatataattgacgaagcgggtcag aggaacttctccaaagcgcttgcggttgctaagcaggtcttcaactcattaacggagtac atacagggtccatgcataggcaaccaacagagtctggctcatagcagattgtgggatgcg gtcgtgggcttcctgcatgtttttgcaaatatgcagatgaagttatcccaggactccagt caaattgaattgttaaaggagctgctggacctgcagaaggacatgatcgtcatgatgctc tctcttctcgaaggaaatgtcgtcaatgggaccatcgggaaacaaatggtggacaccttg gtggaatcatctagcaatgtagaaatgattctcaagttctttgacatgttcctcaagtta aaggacctgaccacctcagacagcttcaagatctatgatgccgaatgcaaaggttttatc tccaagaaggatttccagaagtccatggagaaccagaagcaatattcccagtcggagatt gagtttcttctgtcttgcgccgaagcggatgagaacgacatgttcaactatgtgcagttt gtggaaaggttccatgagcccgctaaggacattggcttcaacgtggctgttcttctaaca aacctctcggagcacatgccacacgatgctcgcctctccacgttccaggatctggccgag agtgtcctcagctactttgaaccctacttgggtcgtatcgagatcatgggcggagctaag cgcatcgaacgcgtttacttcgacatcagcgagtcgagtcgaacgcaatgggagaaacct caggtgaaggagtccaagcgacaattcatctttgatgttgtcaatgaaggcggagaaagc gagaagatggaactgtttgtgaatttctgcgaggataccatttttgagatgcaactagct tcgcagatttcagagccggacccggtggagcgccaggaagaagaagacgaagatgatagc cagagcttggcggagaaccaggaggaggaagaggagcagaatttgatgttggagtcttca tcagcatttaccatcgcctgtatctccatgagaaagaatatctgccacgttcgccagatg ctgactttcaagagcatgaaacggcagtacagaaaattccgaaagatgagcgtgagggag acggtacacgggttttttgcgttcttctggatgatcatcactggcctcttccactttgtc tacagcttggtttggggtttcttccatattttgtggaccaccatgtttgggggtggcctc gttgaaggggcaaagaacatgaaggtcacggacattctgggaaatatgcccgatcccact cagttcggaatccacggggatgttctggagacagacaagatggaggcgcatgaggcgtcg gcattgactgaaatgggtcacatggctcagggggaagtggccgagggagacctgatggct gagctgctcaacatccagcccaagaaggaaggcaagcatggagcagagcccggattgggg gacgtgtctgaagtggttgtcgggggcgatgctccatccatagccagtgctgtcaagcag aagaaggctcagatggctgccaagaaccgggcatcaaatggagactacaaatccgattca gagaaagcagactctgatgacggtgagaagaaggaccacgacaaggccaaggatgaagcc cctcctgctcttccactggaaaagaaaacccccaagaagaggctcgacgtaaagaaagac ccaccggaggccttcatggctagcttctttgctggcttagaaatctaccaaaccaagatg ctgaactacctggccagaaacttctacaaccttcgatttttggcactctttgtcgcattt gccatcaacttcattcttctcttctataaagtgaccggcgataactctgatgatgaggat ccttggaatggtcatgggagaactgtagaagaagaggaagaagataactctcttgaatat tttatcctacaagagagtacgggctatatggcgccaacgcttcgctgtctggcaatacta cacacgattatatcgtttttgtgtgtagtgggatactactacctgaaggttccactggta gtgttcaagcgtgagaaggagatagccagaaagttggagtttgctggactctacatcacc gagcagccgtccgatgacgatattaaaggacagtgggacagaatggtcattaatacaccg tctttccccaacaactactgggataaatttgtcaaacgaaaggtgattaaaaagtatggc gacttgtatggcgccgaaaggattgcagagctgctgggattggacaaaagcgctctggat tttaatccgacggaggaagccgtcaccaaggaggcttcattggtgtcctggttgagctca atcgatacgatgtatcatatctggaaaatgggggtggtgtttacagacaactccttcctt taccttgtgtggtacacgaccatgtccattctgggccactataacaacttcttctttgct gcacatctgctggacatcgcaatgggattcaagacgcttcgcaccattttgtcctcggtc acccataacggcaaacagctggttttgacggtggggcttctggccgtcgtggtctacctc tacactgtggtggccttcaacttcttcaggaagttctacaacaagagcgaagatgacgac gagccagacatgaagtgtgacgatatgatgacttgctacttattccacatgtatgtgggc gtgagagcggggggtggcattggtgatgagatcgaagacccggctggcgatccctacgag ctataccgcatccttttcgacatcaccttctttttcttcgtcatcgtcatcctcttggcg atcattcagggtttgatcattgatgcttttggagagctgagagaccagcaggaacaagtc aaagaagacatggagacaaaatgttttatttgtgggatcggaaacgactactttgacaca acacctcatggctttgagactcacactttgcaagagcacaatttggccaattacctgttt ttcctgatgtacctcatcaacaaggatgagaccgagcacactggccaggagtcatatgtg tggaagatgtaccaggagcgttgctgggatttcttcccagccggagactgcttccgtaaa cagtacgaagatcagctgggttaa

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