Syngnathus scovelli (Gulf pipefish): 125989738 Help Entry 125989738         CDS       T08785                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism sscv  Syngnathus scovelli (Gulf pipefish) Pathway sscv04020   Calcium signaling pathway sscv04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sscv00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     125989738 (ryr3)    04020 Calcium signaling pathway     125989738 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sscv04040]     125989738 (ryr3) Ion channels [BR:sscv04040]  Voltage-gated cation channels   Ryanodine receptor    125989738 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 Phage_TAC_15 Motif Other DBs NCBI-GeneID:  125989738 NCBI-ProteinID:  XP_049611963 LinkDB All DBs Position 20:8875252..8918307 Genome browser AA seq 4831 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQSVATIQKEHRKFCLAAEGLGNRLCYLEPTSEAKYVPP DLCICNFVLEQSLSVRALQEMLANTGQSSEGAGQGGGHRTLLYGHAILLRHSFSGMYLTC LKTSRSLTDKLSFDVGLQQESIGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSTERYL HLSISNSNIQVDASFMQTLWNVQPTCSSSNMAVGYLVGGHVMRLCRGHDENLTIPGAERS DEEQRIVNYEAGKGASKARSLWRLEPLRISWSGSHIRWGQAFRLRHLSTGHYLALTEDRG LVLQDRERSDITVTSFCFRPSKEKSESGLKRDIEGMGVPEIKYGDSVCFIMHVATGLWLS YQALDAKSSRLGPVKRRACLHSEGHMDDGLTLQRCQHEESQAARNIRNTTFLFNNFIKAL DSTTAGESKEMAGYVEAVLQTLNDLIKYFKQPDSELEHEEKQCLLRSLIKRQDLFKEEGM LALLSKCIDRMNLFNSAAHFGEMAGEEAGAAWKDILNLLYELLAALIRGNRNNCTQFSRN LDWLVSKLERLESSSGILEVLHCVLIESPEALNIIQRGHIKSIISLLYKHGRNHKILDVL CSLCVCNGGAVRANQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGVAEGSAQYKKWY FELVIDQVDHFVTGDATHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYSFDGLHLWS GRIPRAVASINQHLLTSDDVVSCCLDLGSPSMSFRINGQPVQGMFEDFNTDGFFFPVISF SAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMFVEPVKEYKRDHEGVRDLLGTT QFLSQASFIPTPVDTSQVVLPPHMDNIRDKLAENIHELWGMNKIELGWTYGKVRDDNKRQ HPCLVDFPKLPETERNYNLQMSSETLKTLVALGCHVAQVNIHAEDDLKKIKLPKDYMMSN GYKPSPLDLSDVKLTGGQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSRRNPRLVP YALLDERTKKSNRDSLREAIRTMVGYGYEIDPPDQEAVHVTENQSVETLRFFRVEQIYAV KTGKWYFEFDALTGGDMKVGWARPGCRPDVELGTDDQAFVFDGYRARRLHAGSRFFGHPW KKGDVVGCMINMEDKSIIFTLNGELLITNKGSELCFTDFDTEDGFIPVCSVGMSQIGRMN LGKDASTFKYYTTCGLQEGFEPFAVNMNREITMWFSKRLPTFVNVPQDHKDIEVTRIDGT VDSPPCLKVTHKTFGTQNSNNDMIYCRLSMPVELFSADVLLEETSKLSHPPKEYGVTDYG SITTYYHSVRVFAGQDPALVWVGWVTPDYHYYSKNFNLNKTRTVTVTLGDERGRVHESVQ RSNCYMVCGADAVSSSSSSRSNSDVEIGCLMDLATGLVSFTANGKELSTTYQVETSTKLF PAVFVRPTCANLFQFEFVKIKDAMPISSAMFKSEHRNPVPQCPPRLDVQTISAVLWSRMP NTFLSVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDILELSEYEDLRKFHYHTLKL YCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLISIHLETAKEARLM MNNEFIIPVTDETRSIKLFPDESKKHSLPGVSLSTSLKPRVNFSPAGIVGTKRQQYLHSP QIPLGILKEKAISMLTEAVQGGGIHIRDPVGGSVEYQFVPILKLIGTLLIMGVLNSEEVR LILLLIDPNVFGEGEEAKVDDSGENLSEEKVTEVGEGEAKESKATVRGLLEKSLPESVKR QMCELLHYFCDCELKHRIEAIVSFSDNFVSKLQYNQKFRYNELMLALNMSAAVTAKKTKE FRSPPQEQINILLNFTTGDDCPCPEDLQEELIAFHEELQLHCGIPVEEDEVEQDTSIKGR LLALLYKIKGPPQKTEEEPEEKEQACPTNLKELISQTITTWAQETHMQDPELVRVMFSLL RRQYDGIGELLRAMKKSYTISAASVQDAINLLASLGQIRSLLSVRMGMEEEKLMIDGLGD IMNNKVFYQHPNLMRVLGMHETVMQVMVNVLGGDKSQEIAFPKMVASCCRFLCYFCRISR QNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNNGLALALEEPDLEKVVTY LAGCGLQSCAMLVAKGYPDLGWNPIEGERYLSFLRFAVFCNGESVEENANVVVKLLIRRP ECFGPALRGEGGQGLLAAMKEAIKISKDPALDLPKPSAAITTGSGEEEEEIIHMGNAIMS FYSALIDLLGRCAPEMHLINEGKGEALRIRAILRSLVPTTDLVGVISIPLTKPVVNKDGQ VTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLLQLLEVGFLPDLQTAASLDTEVLSTT ETALAMNRYIGSALLPLLTRCAALFANTEHYAHLIDATIQTIYRLSKGRSLTKAQRDVIE ECLLTICKHLRPSMMQQLLRRLVFDVPMLTEYCSIPLRLLTNHYEQNWKYYCLPPGMNTF GTASEEELLLTKKLFWGIFDSLSQKKYDGELFKMANSCLCAIAGALPPDFVDASLGTTLE NQASVDAQGNFDPKPINTANISLPEKLEYIANKYAEHSHDKWSSEKVSAGWKHGDSMDEH AKKHPLLKPYKSLSEKEKETYRWPARESLKSMLAMDWNIEKTKEGEALFQQRETEKQRKI SETQVNGYTPAPIDLHDFTLSRELQGMVEVIAENYHNIWAKKKKSELMSKGGGSHPLLVP YDTLTAKEKYRDREKAQELFKFLQISGYSITRGLKDLEQDSSSMEKRFAYKFLKRLLKCV DSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLTDQTFKNHCLYFLSTPSKNLSS CGYASNKEKEMVTSLFCKLAALVRHRISLFGSDSSMMVSCLHILTHSLDTRTVMKSGTEL VKAGFRTFFDNAAEDLEKLLEMLKLGKFMQSRAQMKSVSQSIHYVTVALVPILTAVFDHI KTHDFGVDLLLDDVQLSCYRILTCYYYLGTGKNIFVERYLPALGESLATLVGAMPVAFLE PHLNSHNPLSVFNTKTPRERAILSMPDTVEEMCPEMPRLDKLLKDVNDVSETGARYNEMP QVIEVILPMLCNYLSYWWEKGPENPPASGECCTMVTSEHLSIILGNILKLLNNNLGIEDA PWMKRIAVYSQPIISKAEAGLLRTHFLPTLEKLKKKTVKVVSEEELLKADGKSDNQEAEL LILDEFAVLCRDLYAFYPMLIRYVDINRSRWLKEPDTDSTELFRMVADIFILWCKSHNFK REEQNFVVQNEINNLGLLTGEGKAKLSKSGGDQERKHKRRRGEYYSIHTSLIVAALKKML PIGLNMCTPGDQELISLAKTRYSLKDTDDEVKDYLRQNLHLQDKSDDPAVQWQLNLYKDI TMKSDEPVNPEHTVDRVQSISAAVFHLEQVEQPLRNKKCVWQKLLSKQRKRAVVACFRMA PLYNLPRHRAINLYIPAYQRIWIEAEEYSFEEKLVQDLAKTPMKIVEEDEEEVAEVQPDP LHQLILHFSHNALTERSHLEEDPLYIAYADMMAKSCAEDEEEEDEEEKEKTFEEKEMEKQ KILYQQARLHARGAAEMVLQMISASKGHLGSMVTCTLKLGISILNGGNVQVQQKMLDYLK EKRDASFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSVHTERGSKVLLNDEFTK DLFRFLQLLCEGHNGEFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDI IDETGKINFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMK LSQDASQIELLKELMDLQKDMVVMLLSLLEGNIVNGTIGKQMVDTLVESSNNVEMILKFF DMFLKLKDLTTSDNFKEYDPECKGVISKKEFQKSMESQKQYSQSEIGYLLSCAEADENDM FNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLAAFLDLAESVLSYFEPYLGRIE INGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEGGESEKMEMFVNFCEDTI FEMQLASQISEPDAVEQQEEEDEEEGFTILDELAGEDGSSESASAFTSACRSIKKKLHHA RQMVSVKNIRKKLRKLKKLSIREIITCCFSFFWMLFTGFFKGIASLIFGFFHVIWSSMFG GGLVEGAKNIKVTDILGNMPDPTQFGIHGDTVEGEKLEAIESSGTSDATMVPPADIAEVD TMLDMLNVPKREGGKLVEHGLGDVSELNSETSTTDPKKTAAKADESPESEPEKADTENQE KEDQAKKEEAKEPPTEEKPKVKSSRPKEASPAFMSKVFSTLDVYLTKMLNYLARNFYNLR FLALFVCFAINFILLFYKVTAEEEGDDENHWEKDDEDTLFDMDEFVLQESTGYMLPTLRF LAIFHTVISLVCLVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSDEDIKGQWDRLV INTPSFPNNYWDKFIKRKVINKYGDLYGAERIAELLGLDKTALDFDPTVETVEKEASLLS WLSSIDTKYHIWKLGVVLTDNSFLYLIWYTIMSIFGHFNNFFFAAHLLDIAMGFKTLRTI LSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRRFYNKSEDEDEPDMKCDDMMTCYLFH MYVGVRAGGGIGDELEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQ QEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQ ESYVWKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14496 nt NT seq  +upstreamnt  +downstreamnt atggccgagggcggggaaggggaggacgagatccagttcttgagaactgatgacgaggtg gttcttcagagcgtggccaccattcaaaaggagcatcgcaagttttgcctggccgccgag ggacttgggaaccgcttatgttatctggaacccacctctgaagctaagtatgttcctccg gatctgtgcatttgtaactttgtgctggagcagtcgctgtcggtgcgagccctgcaggag atgttggcgaacactggacaaagcagcgagggggcgggtcaaggaggcggacatcggacc ttgctctatggccacgccatcctcctgcgccattccttcagtggcatgtacctgacctgt ttgaagacatcacgttctctgacagacaagttgtcattcgacgtggggctacaacaagaa tccataggagaggcctgttggtggaccatccacccggcctccaagcagagatccgaagga gagaaagtccgcatcggagacgacttgattcttgtcagcgtgtcaacagaaagatacttg cacctctccatctctaatagcaacatccaggtggatgcatccttcatgcaaaccctgtgg aacgtccaacccacctgctcctcaagcaacatggctgtcgggtatttggttggtggtcat gtgatgcgtctttgtcgtggccatgatgagaacttgaccatccctggagcagaaaggagc gatgaggagcagaggatagtcaactatgaggcaggtaagggagcgtcaaaagcacgttcc ctgtggcgactggagcccttgaggatcagctggagcggaagccacattcgctggggtcag gccttccgactacgtcacctctccaccggccattatctggcactgactgaggaccggggt ctggtcctgcaggacagggagaggtctgacatcacggtcacctccttctgcttcaggcct tccaaggaaaaaagcgaatcgggtctaaagagagacatcgagggcatgggtgtacctgag atcaaatacggcgattcggtctgcttcatcatgcacgtggcaaccggattgtggctgtcc tatcaagcgcttgatgccaaatcatctcgtcttggacctgtgaaaagaagggcctgcctg cattctgagggccacatggacgacggcttgactctgcagcgctgtcagcacgaagagtct caagctgctcgcaacatccgcaatacgacgttcctcttcaacaacttcatcaaggcttta gacagcaccacggcgggcgagtcaaaggagatggccggctatgtggaggcggtgctacag acgctgaatgacctgataaagtacttcaagcagcccgactcggagctggaacacgaggag aagcaatgtctcctgcgttcgctcatcaaacgtcaggatctcttcaaagaggagggcatg ctggccctcctgtcgaaatgcatcgaccggatgaacctgttcaacagcgccgcccacttt ggggagatggctggggaggaggcgggggcagcgtggaaggacatcctcaacctcctctac gagctgctggccgcactaattcgtggaaacagaaacaactgcacccagttttctcggaac ttggactggttggtcagcaaactggaaagactcgagtcatcatcaggcattctggaagtt ctacactgtgtcctcattgaaagtccagaggccttgaacatcatccagagaggacatatc aaatccatcatctctctgctgtacaaacacggacgcaaccacaagattctggacgtcctt tgctccctttgcgtatgtaacggtggagctgtgcgagccaatcaaaacctgatatgtgac aacctgcttcccaaaagggacctgcttcttcaaacccgactagtcaatgatgttcaaagc atgaggcccaacatctttttgggtgtggccgaaggctcggcccaatacaaaaagtggtat tttgagctggtgatcgatcaggtggaccactttgtcacgggtgacgccactcacctgagg gtgggctgggctaacacaaaaggctacgccccgtatcctggtggaggcgagggatgggga ggcaatggcgtgggtgatgatctctactcttacagctttgatggtcttcacctgtggtca ggtcgcatcccacgggcagtggcgtccattaaccagcacctgctgacctcagacgacgtg gtcagctgctgtctggacttgggctcccccagcatgtccttccggatcaacggtcagccc gtgcagggcatgtttgaagacttcaacacggatgggttcttcttccctgtcatcagcttc tctgctggtgtcaaggtgcgttttttgttgggtggacgccatggagatttcaaattcctg ccccccgctgggtactctccgtgttatgaggcactgctgcccaaggagaagatgttcgtg gagcctgtgaaggagtacaagagggatcacgaaggggtccgagacctgttaggaacgacc cagtttctctcccaggcctccttcatcccaactccggttgacaccagccaggttgttctt ccgcctcacatggacaacattcgggacaagctggcagaaaatattcacgaactgtggggg atgaacaagatcgagctgggatggacgtatggaaaggttcgggatgacaacaagaggcag cacccgtgccttgttgatttccccaagctgcctgaaacagaaaggaactacaacctgcag atgtccagtgaaacacttaagacccttgtggctcttgggtgtcatgtcgcccaggtcaat attcacgcagaggatgatctgaagaaaatcaaacttcccaaagactacatgatgtccaat ggttataagccttcccctctggacctttctgatgtgaagctgactggaggtcaggagctt ctggttgataagctagcggagaatgcacacaacgtgtgggccaaagatagaattaaacaa ggatggacttacggaatccagcaggatttaaaaagcagacgtaatcctcggttggtacca tatgctttacttgatgagcgcacgaagaaatccaatcgagatagtttaagggaggccatc aggaccatggttggctatggatatgaaatcgaccctccagaccaggaggctgtccacgtg acggagaatcagagcgttgagactctccggttcttccgcgtggagcaaatttacgcggtg aaaaccgggaagtggtacttcgagtttgacgccctgaccgggggcgatatgaaggttggc tgggccaggccaggctgcagacctgatgtggaacttggaacagatgaccaggcctttgtc tttgatggatacagggctcgacgcttacacgccgggagccgtttcttcgggcatccgtgg aaaaaaggagacgtagtgggatgcatgatcaacatggaggacaaatcgattatttttacc ctgaacggcgaactcctgattaccaacaaaggctccgagctttgcttcactgactttgac acggaagacggttttatcccagtgtgtagcgtgggcatgtctcagatcggccgaatgaat cttgggaaggacgccagcaccttcaaatattacaccacgtgtggccttcaagaaggcttt gagcccttcgctgtcaacatgaaccgagaaatcaccatgtggttcagcaaacgcctgccc acttttgtcaacgtgccccaggatcacaaagatattgaggtgacgaggattgacgggacg gtggacagccctccctgccttaaagtcacccacaagacatttggcacccagaacagtaac aacgacatgatctactgccgactgagcatgcccgtggagttgttctctgcagacgtgcta ctcgaggaaacatcgaaactcagccatcctccaaaagaatacggggttacagactacggg agcatcacaacttactaccactcggttcgagtctttgccggacaggaccctgcgttggtg tgggtgggctgggtcacgccggactatcattactattcaaagaacttcaacctcaacaag accagaaccgtcaccgtcaccttgggagacgagaggggccgagtccacgagagtgtccag agaagtaactgctatatggtgtgcggggcggatgcagtcagctcctcttcatccagccgc tccaactctgacgtggagattggctgtctgatggacctggctaccggccttgtctccttc actgctaacggcaaggagctgtctaccacttatcaggtggagacaagcacgaagctgttc cctgctgtgtttgtccggcccacctgtgcaaacctctttcagtttgaatttgtcaagatt aaggatgccatgccaatctcctcagctatgttcaagagcgagcacaggaacccggtgcct caatgcccgccgcgactggacgtgcagaccatttcggcggtgctgtggagccgcatgcca aacaccttcctcagcgtggagacggctcgagtcagcgaaagacacggatgggttgtccag tgcttggaacctctgcagatgatggctgtgcatatacctgaggaaaataggtgtttggac atcttggagttatccgaatatgaagatttaaggaagttccattatcacacgctgaagttg tactgtgccctctgtgctcttggtaacacccgtgtagctcatgcgctctgcagccacttg gaccaatctcagctcctctacaccatcgacaatcagtatctctccggcatgttgagggaa ggcttctacaatgtcctcatcagcattcatctcgaaacggcgaaagaggctcgcctaatg atgaacaatgagttcatcatccctgtgaccgatgagacccgctcaatcaagctgttcccc gatgagagtaaaaaacactcgctacccggcgtgagcttgagcacgtccttgaagccccgc gtcaatttctcccccgccgggatcgtcggcaccaagcgtcagcagtatctccacagtcct cagatacccctgggcatcttaaaagagaaggccatcagtatgcttactgaagccgtgcag ggtggtggcatccatatcagggatccggtgggcgggagcgtggagtaccagtttgtgccc atcctcaagctaatcggaaccttgttaatcatgggtgtgttgaatagcgaggaggtgaga ttgattctcctcttgattgatcccaacgtgtttggggagggtgaggaggcaaaggtggat gatagcggagagaatctgagtgaggagaaggtcacggaggtgggagaaggagaggccaag gagagcaaggcgacggtccggggccttctggagaagtctttgcccgagtccgtcaaacgg cagatgtgcgagctactgcattacttctgcgactgcgagctgaagcaccgcatcgaagcc atcgtttccttctccgacaactttgtgtctaagctgcagtacaaccagaaattccgttat aatgaactcatgctggcgctcaacatgtccgccgccgtcacggccaagaagaccaaagag ttccgctcacctccacaagagcagatcaacatcctgttgaacttcaccacaggcgacgac tgcccctgtcctgaggacctccaggaagaactcattgccttccatgaagaactgcagctg cactgtggaatcccagtggaggaggacgaggtagagcaggacacatcaattaaaggtcgt ctcctggccttgctgtacaagatcaagggtccgcctcagaagactgaagaggaacctgaa gagaaagagcaagcatgccccactaatctaaaggagcttatctcccagactataaccacc tgggcccaggagactcacatgcaggatcccgagctggtccgagtaatgttcagcttgcta aggaggcagtatgacggcatcggggagcttcttcgggccatgaagaagtcctacaccatc agtgccgcgtccgtgcaggatgctattaacctcctggcctcactgggtcagatcaggtct ctgctgtctgttcgcatgggcatggaggaggaaaagctgatgattgatggactgggggac attatgaacaataaggttttctaccagcatccaaacctcatgagagtgttgggcatgcat gaaactgtcatgcaggtcatggtcaatgtgctgggaggagacaagtctcaggaaatcgcc ttccccaaaatggttgcaagctgttgtcggtttttgtgctatttctgccgtattagccgc cagaaccagaaagccatgtttgaccatctcagctacctgctggagaacagcagtgttggg ttggcttctgaagcgatgcggggttccacgccgctggatgttgccgcatcatctgtgatg gacaacaacgggcttgctttagccctggaggaaccagatctagagaaggtggtgacgtac cttgcaggatgtggtcttcaaagttgtgccatgctggttgccaagggttacccagatctt ggttggaaccccatcgaaggggagcgatacctgtccttcctgaggtttgcggtcttctgc aatggtgagagtgtcgaggaaaacgccaacgtggtggtgaagctgctgatccgacgtcct gagtgtttcggtcctgctctgagaggagaaggaggtcagggtcttttagcggcgatgaaa gaagccatcaagatatcgaaggatcctgctctagacctgcccaaaccttcagctgccatc accactggatctggtgaagaagaggaggaaataatccatatgggcaacgctatcatgtcc ttctactctgccctcattgacctgctaggtcgctgtgctccagagatgcatctcatcaat gaaggtaaaggtgaagctctccgaattcgagccattctacgctcgctggttcccaccaca gatttggttggcgtcatcagcatacccctcacaaaacctgtcgttaataaagatggccaa gtgaccgaaccagatatgtcagcctgtttctgtccggatcacaaggcccccatggtgctc ttcctggatagggtgtacggtatcgaggaccaaagctttctcctccagctgttggaggtc ggcttcctgcccgacctccaaactgctgcctctttagacacggaagtgcttagtaccacc gagacggcgttagccatgaacaggtacatcggctcagctctgctgcctctgctgacccgc tgcgctgccttgttcgccaacacggagcactacgcccatctgatcgacgccaccattcaa accatctatcgcctctccaaaggacgttcgctcaccaaagcacagagagatgttattgag gagtgcctgctaactatctgcaagcatctgcgtccctccatgatgcagcagctgctcaga cgtttggtgtttgacgttcccatgctcacggaatactgcagcatccctctaaggctgctg accaaccactacgaacagaactggaagtattattgtctgccacctgggatgaacaccttt gggacagcctcggaggaggaactccttctcaccaagaaactcttctgggggatttttgac tcactctctcaaaagaaatatgatggtgaactcttcaaaatggccaactcctgcctttgt gccatcgctggagccctgccacctgactttgtagatgccagtttaggaacaacgttggag aaccaagcgtccgttgacgcacagggaaactttgaccccaaacccatcaatactgccaat atctccttacctgaaaaacttgaatacattgccaacaaatatgcagagcattcccatgac aagtggtcttcagagaaggtgtcagcagggtggaaacatggagatagcatggatgaacat gccaaaaagcatccactgctaaagccttacaaatctctaagcgaaaaggaaaaggaaact taccgatggccggcgagggagtcgttgaagagcatgctggccatggattggaacattgag aagaccaaggagggagaagccttgttccaacaacgggaaactgagaaacagcgaaagatc tcagagacgcaggtcaatggatacactcctgctccaatagacctgcacgatttcacgttg tccagagagcttcagggcatggttgaggtgattgcagaaaattatcacaacatctgggcc aagaagaagaaaagtgaactcatgagcaaaggaggagggagccacccactgctggtaccc tatgataccctgactgctaaagagaagtacagagatagagagaaggcccaggagctcttc aagttcctgcagataagcggctattccataacaagaggtctgaaagacttggagcaggac tcttcatccatggagaagcgttttgcctacaagtttctcaagaggctgctcaaatgtgtc gactctgcgcaggagtttatcgcacaccttgaggcaatggccaccagtgggaagactgac aaatcacctcatgaccaagaaatcaagttctttgctaaggtgttgctcccgctgacggat cagacttttaagaaccactgcctctactttttgtccacgcctagcaagaaccttagcagc tgcggctatgcttccaacaaagaaaaagagatggtcacaagccttttctgtaaactggca gctcttgtcagacacaggatttccctctttggaagtgactcttcaatgatggtgagctgc cttcatattctaactcactcacttgacaccagaacagtgatgaagtcaggtacagagctg gtcaaagcagggtttcggaccttctttgataatgcagctgaagacctggagaagcttctg gagatgctcaaattggggaagttcatgcagtcgcgtgcccagatgaagagtgtcagtcag agcattcactacgtgactgttgcacttgtgcctatcctcactgccgtatttgatcacatc aaaacacacgattttggtgtggacctgctgttggatgacgttcagctgtcctgctaccga atccttacttgttactactacctgggtacaggaaagaacatttttgtggaaaggtatctg ccagcacttggtgagagcctggccactctagtgggcgccatgcctgtagctttcctggaa cctcatctcaacagccacaatccactgtccgtcttcaacaccaagacaccacgcgagagg gccatcttaagtatgcctgatacggtggaggaaatgtgtccggagatgcctcgtcttgac aagctgctcaaggatgtcaacgatgtctcggagactggtgcccgctacaatgagatgcca caggtgattgaagtgatcctgcccatgctgtgcaactacctgtcctactggtgggaaaaa ggtcctgaaaacccacctgcgagtggcgagtgctgcaccatggtgacatcagagcacctc agcatcattctcgggaacattctcaagctcctcaacaacaacctgggcattgaggatgcc ccctggatgaagaggatcgcagtctactctcagcccatcatcagtaaagcagaagctggt ctgctgagaacccactttttaccaacacttgagaaactgaagaagaagacggtgaaggtt gtgtctgaggaggaattattgaaggctgacggcaaaagtgacaatcaggaggcagagctt ctcatcttggacgagtttgctgtgctctgccgagacctttatgccttctaccccatgctt attcgatatgtggacatcaacagatcgagatggcttaaggagcctgataccgactccact gagctctttcgaatggtggcagatatcttcatcctctggtgcaagtcacataattttaag cgtgaggagcaaaattttgtcgtgcagaatgagatcaataatttgggcttgctcactgga gaaggcaaggccaaactgtccaagtctggtggcgaccaggagaggaagcacaagcgtcgt cgtggcgagtactactccatccacacctctttgattgtggccgcgctgaagaagatgctg cccatcggcctcaacatgtgcacgccaggggaccaggagctcatctccttggctaagacc cgttacagtttgaaagatactgatgatgaagtgaaggactacttgcgccagaaccttcat ctgcaggacaagtctgacgacccggcagtccagtggcagctgaacctctacaaagacatc accatgaagagtgacgagccagttaacccggaacacacggtggatcgggttcagagcatc tcggccgcagttttccatctggaacaggtggagcagcctttaagaaataaaaagtgtgtg tggcagaagttgctgtccaaacaacgtaaacgggctgtggtggcctgctttcgaatggcc cctctttataatctacctaggcatcgtgctatcaacctctacatcccggcctatcaaaga atatggatagaggcagaggagtactcctttgaggaaaagctagttcaggatttggcaaaa actcccatgaaaattgtggaggaggatgaagaagaggtggctgaagtccagccagatcct ctacaccaactcatcctccattttagccacaacgctctaacggaaagaagtcacttagaa gaagatcctttgtatattgcatacgctgacatgatggcaaagagctgtgcagaggatgag gaagaagaggatgaagaagagaaagagaagacgtttgaggaaaaggagatggaaaaacag aagattctctaccagcaggctcggcttcacgctcgcggggcagccgagatggtgttgcag atgattagcgctagcaaaggacacctgggctcgatggtgacttgtaccctcaaactcggc atttccatcttaaacggaggcaatgtgcaagttcagcaaaaaatgctggattacttgaaa gaaaaaagagacgcaagcttttttaaaagcctctcaggactgatgcagtcgtgcagtgtc ctggacttgaatgcatttgagagacagaataaggcagaaggactcggcatggtgacagag gaaggttcagtccacactgagcggggttccaaggtgttactgaatgacgagtttacaaaa gatctgttccggtttttgcaacttctttgtgaggggcacaatggggagttccagaacttc ctgagaactcaaactggaaacacaaccacggtcaatattattatcagcactgttgactac ttgctccgccttcaggaatcaatcagtgacttctactggtactactctggcaaagacatc attgatgaaactggcaaaattaacttctccaaagcgttatcggtggctaagcagatcttc aactccttgactgaatatatccagggcccttgtattgggaaccagcagagtcttgctcat agcagattgtgggatgcagtggtaggcttcttgcatgtttttgccaacatgcagatgaaa ctgtctcaggatgccagtcagatagaactgctaaaggaacttatggatttgcagaaagac atggttgtcatgctgctgtctcttctagaagggaacattgtgaatggaaccatcgggaag cagatggtggacaccctggtggagtcttcgaacaacgttgagatgatcctgaaattcttt gatatgttcctcaagctgaaggatttaacaacgtcggataatttcaaggagtacgaccct gagtgcaagggagttatctcaaagaaggagtttcagaaatccatggagagccaaaagcag tacagccaatcggagatcggctacctgctttcttgcgccgaggccgacgagaacgacatg ttcaactacaaggaatttgtggagcgattccacgaaccggcgaaagacatcggtttcaat gtggccgtgttgctgacgaacctttccgagcacatgccgcacgatagccgactcgccgcc ttcttggatctggccgagagtgtgctgagctactttgagccctacctggggcgtatcgaa atcaacggcagtgcaaaacgtatcgagcgggtgtactttgagataagcgaatccagccga gaacaatgggagaagcctcaagtgaaagagtccaagcgccagttcatttttgacgtggtc aatgagggaggcgaaagtgagaagatggagatgtttgttaatttttgcgaggacaccatt tttgagatgcaactagcctcgcagatctcggaacctgatgctgtggagcaacaggaggag gaggatgaggaggagggattcaccatcctggatgaattggctggagaagatggctcctca gaatctgcctccgctttcacttctgcgtgtcgatcaatcaagaagaagttacatcacgca cggcaaatggtttccgtgaaaaatatccgcaagaagctcaggaaactcaagaagctgagc ataagggaaataatcacatgctgcttctctttcttctggatgctcttcactggcttcttc aaaggaatcgctagtctcatatttggtttcttccacgtcatctggtcttccatgttcggc ggcggtttggtggaaggtgccaagaacatcaaagtgacagatatccttggaaatatgccc gatcccactcaatttggcatccatggagataccgttgaaggagagaaattagaggccatc gagtcttcaggaacctctgacgcaactatggttccaccggcagacatagctgaggttgac acgatgctggacatgctgaacgtgcccaagagggaaggtggaaaacttgtggagcacgga ctgggggatgtctctgaactcaatagtgagacctccaccacagaccccaagaaaactgct gccaaggctgatgaatctcctgagagtgaacctgagaaagcagacacagagaaccaagag aaggaagatcaagctaagaaagaggaagccaaggaaccaccaactgaggagaaacccaaa gtgaaatcaagccgacccaaagaagcttctcctgccttcatgtccaaagtcttttccacg ctggatgtctatctgaccaaaatgctgaattacctggctcgcaacttctacaatcttcgt ttcctggctctgtttgtctgtttcgccatcaatttcattttgctcttctacaaggtcacg gcagaggaagaaggagatgatgagaatcattgggagaaggatgacgaggacacgctcttt gacatggatgagtttgttctccaagagagcacgggctacatgttgccaaccctgcgtttc ctggccatattccacacagtcatctccctcgtgtgtttggtgggatactactgtctgaag gttcctttggtggtgttcaagcgagagaaggagatagccaggaagctggagtttgacggc ttgtacatcaccgagcaaccatctgatgaggatattaaaggccagtgggatcgactggtt atcaacaccccgtcttttccgaataactactgggacaagttcatcaaacgcaaggtgatt aacaaatatggggacttatatggagccgagcgcatcgccgagctcttaggcctggataag actgctctggactttgaccccaccgtggagactgtcgagaaggaagcttccctgctatcc tggctgagctcaattgacacaaaatatcacatttggaaattgggagtggttttgactgac aattctttcctgtatctgatctggtacactattatgtccatttttggacacttcaacaac ttcttctttgctgcccatctgctggacattgccatgggcttcaagactctccggaccatc ctgtcttcagtcactcacaatggcaagcaattggtgctgacagtgggtctgctggcagtg gttgtgtatctctacacagtggtagccttcaacttcttcagaaggttctacaataagagc gaggacgaagacgagccggacatgaagtgtgacgacatgatgacgtgctatctcttccac atgtacgtgggtgtaagagctggagggggtatcggtgatgagttggaggacccggctgga gacccttacgagctctaccgcatcctttttgacatcaccttcttcttctttgtcattgtc atcttgctggccatcattcagggtttgatcattgatgcctttggtgagctgagagaccag caggagcaagtgaaggaggacatggagaccaaatgcttcatctgcggcatcgggaacgac tactttgatcggacgcctcacggttttgaaactcacaccttacaggagcacaaccttgca aactacctgttctttctgatgtacctgatcaacaaggatgagacagaacacacaggccag gagtcgtatgtgtggaagatgtaccaggaaagatgctgggacttcttcccgaccggagac tgtttccggaagcaatatgaggaccagttgggctaa

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