Streptomyces secundicynarae: ABZO29_06945
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Entry
ABZO29_06945 CDS
T11405
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
ssec Streptomyces secundicynarae
Pathway
ssec00270
Cysteine and methionine metabolism
ssec00480
Glutathione metabolism
ssec01100
Metabolic pathways
ssec01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ssec00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ABZO29_06945 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
ABZO29_06945 (egtA)
Enzymes [BR:
ssec01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
ABZO29_06945 (egtA)
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GFIT
Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
XCW08091
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Position
1479198..1480541
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AA seq
447 aa
AA seq
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MSDSVSDCSDCTEAPAAVTETGVEDLVSGICFKTGPPRSVGVEVEWLVHELHLPQLPVTP
ERLEAAYAALRTVPLSSPLTVEPGGQLELSSPPAASLMECIGTVSADLDAVRAVLREHDL
AIVGLGTDPWHSPRRYLREARYDAMEACLDRTGPAGRAMMCTSASVQVCLDAGYEEPGPL
GHGRRWWLAHTLGPVLVAAFANSPALDGSPTGWRSTRQLLWMEIGAGRAGAPALDGEPRG
AWARHVLDAPVMCVRRDGPWDVPQGLTFREWIRSGVPRQPTRNDLDYHLTTLFPPVRPRG
HLELRMIDAQPGDDGWIVPLAVTTALFDDPEAAELAYRTVKPLAERALGLPAPHNPLWLD
AARSGLTDPELHEVAVACFGTALEALPRLGATTEVTEAVTAYLNRYVLRGRSPADDLLDR
LRGTDLPQSLLRSTGGTRTAYGKDIRT
NT seq
1344 nt
NT seq
+upstream
nt +downstream
nt
atgtccgattcggtaagtgactgtagcgactgtacggaggccccggccgccgtcacggag
accggggtggaggacctggtcagcggcatctgtttcaagacgggaccaccccgcagcgtg
ggcgtggaagtggaatggctcgtccacgagctgcatctgccgcagctccccgtgacaccc
gaacggctcgaagcggcgtacgccgcactgcggaccgtgcccctgagctcgccgctcacc
gtcgaacccggcggccagctggagctgagctcgcccccggccgcctcgctgatggagtgc
atcggcaccgtctcggccgacctcgacgccgtccgcgcggtactgcgcgagcacgatctc
gcgatcgtcggcctcggtaccgatccctggcactctccccgccggtacctgcgcgaagcc
cgctacgacgccatggaggcctgcctcgaccgcacgggcccggccggccgcgccatgatg
tgcacctcggcgtccgtgcaggtgtgcctcgacgccgggtacgaggagcccggcccgctc
gggcacgggcggcgctggtggctcgcgcacacgctgggcccggtgctggtggccgccttc
gccaactcccccgcactcgacggcagccccaccggctggcgctccacccggcagctgctg
tggatggagatcggcgcgggccgcgccggggcccccgccctggacggcgagccccgcggc
gcctgggcccggcatgtgctggacgctccggtgatgtgcgtacgacgggacggcccgtgg
gacgtgccgcagggcctgaccttccgcgagtggatcaggtccggggtgccgcggcagccg
acccgcaatgacctcgactaccacctcacgacactcttcccgccggtcagaccccgtggc
catctggagctgcgcatgatcgacgcgcagcccggggacgacgggtggatcgtgccgctc
gccgtgacgaccgccctcttcgacgacccggaggccgccgagctggcctaccgcaccgtg
aagccgctggccgaacgcgccctggggctgcccgccccgcacaacccgctgtggctcgac
gcggcccggtccgggctgaccgaccccgaactgcacgaggtcgccgtcgcctgtttcggc
acggccctcgaggccctgccccggctcggcgccaccaccgaggtcaccgaggccgtcacg
gcgtacctgaaccgctacgtcctgcggggccgcagccccgccgacgacctgctcgaccga
ctgcgcggcacggacctcccccagtccctgctccgctcgaccggggggacccgcaccgcg
tacgggaaggacatccgcacatga
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