Streptomyces secundicynarae: ABZO29_32930
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Entry
ABZO29_32930 CDS
T11405
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ssec Streptomyces secundicynarae
Pathway
ssec00300
Lysine biosynthesis
ssec00550
Peptidoglycan biosynthesis
ssec01100
Metabolic pathways
ssec01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ssec00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ABZO29_32930 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ABZO29_32930 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ABZO29_32930 (murF)
Enzymes [BR:
ssec01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ABZO29_32930 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
E1-E2_ATPase
DUF561
DUF7916
Motif
Other DBs
NCBI-ProteinID:
XCW12773
LinkDB
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Position
7243516..7244922
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AA seq
468 aa
AA seq
DB search
MIALSLAEIAEVVGGQTHDIPDPSVRVTGPVVRDSREVVPGSLFVAFAGERVDGHDFAAA
VVEAGAAGVLASRPVGVPAIVVEDVRTALGALARHVVRRLGATLVALTGSAGKTSTKDLI
AQVLQRKAPTVWTPGSLNNEIGLPLTALSATEETRFLVLEMGARGIGHIRYLTELTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPEDGAAILNADDPLVRAMASRTKAKVILF
GESGEADVRAENVRLTDTGQPAFSLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHELGMS
AEEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGKGRRTWA
VLGKMAELGDEALAEHDAVGRLAVRLNVGKLVAVGGREAAWLQLGAYNEGSWGEESVHVS
DAQAAVDLLRSELRPGDVVLVKASRSVGLESVALALLEAGAEGEVAAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcagaagtcgtcggcgggcagacgcacgacata
ccggatccgtcggtgcgggtcaccggaccggtcgtccgggactcccgcgaggtggtgccc
ggcagcctcttcgtcgccttcgccggtgaacgtgtggacggccacgacttcgcggccgcg
gtcgtcgaggcgggcgcggccggtgtcctggcctcccgccccgtcggcgtgcccgcgatc
gtcgtcgaggacgtccggacggcgctcggcgccctcgcgcggcacgtcgtacgacggctc
ggcgccaccctcgtcgccctgaccggctccgcgggcaagaccagcaccaaggacctcatc
gcccaggtgctgcagcgcaaggcgccgaccgtgtggacccccggctcgctcaacaacgag
atcggactgccgctcacggccctcagcgccaccgaggagaccaggttcctcgtgctggag
atgggcgcccgcggcatcggccacatccgctacctcaccgagctgacgcccccgaggatc
ggcctcgtcctcaacgtgggcaccgcccacatcggcgagttcggcggccgcgagcagatc
gcacaggcgaagggtgaactcgtggaggccctccccgaggacggggcggcgatcctcaac
gccgacgatccgctggtacgggccatggcctcccgcacgaaggcgaaggtgatccttttc
ggagagtccggcgaagcggacgtacgcgccgagaacgtgagactcacggacacgggacag
cccgcgttcagccttcacacaccctccgggtgcagtgacgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gcggaagagatcgccaccgcgctctccgaggcgggctccctctcccgctggcggatggag
gtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgccctgcgcgcactcgcggcgatgggcaaggggcggcggacctgggcg
gtgctcggcaagatggccgagctcggggacgaggcgctcgccgagcacgacgcggtcgga
cggctcgccgtccggctcaatgtcggcaagctcgtcgcggtcgggggcagggaagccgcc
tggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcggtcgacctgttgcgcagcgagttgcgcccgggggacgtcgtactc
gtgaaggcgtcccggtcggtgggtctcgaaagcgttgccctggcgctgctcgaggccggt
gccgagggtgaggttgccgcccgatga
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