Solea senegalensis (Senegalese sole): 122782213 Help Entry 122782213         CDS       T07721                                  Name (RefSeq) ryanodine receptor 2-like   KO K04962   ryanodine receptor 2 Organism ssen  Solea senegalensis (Senegalese sole) Pathway ssen04020   Calcium signaling pathway ssen04260   Cardiac muscle contraction ssen04261   Adrenergic signaling in cardiomyocytes ssen04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:ssen00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     122782213    04020 Calcium signaling pathway     122782213  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     122782213    04261 Adrenergic signaling in cardiomyocytes     122782213  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:ssen04040]     122782213    04990 Domain-containing proteins not elsewhere classified [BR:ssen04990]     122782213 Ion channels [BR:ssen04040]  Voltage-gated cation channels   Ryanodine receptor    122782213 Domain-containing proteins not elsewhere classified [BR:ssen04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    122782213 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_5 EF-hand_8 Motif Other DBs NCBI-GeneID:  122782213 NCBI-ProteinID:  XP_043902413 LinkDB All DBs Position LG15:complement(5203028..5270112) Genome browser AA seq 4944 aa AA seqDB search MRDSGDGDDEFQFLRTGDEVVLQSTLTSQEEHVKLCLAAEGFGSRLCRLESTSNCKNVPP DLSVCGFVLAQCLSVRALQEMLAHSQHLAAEIEAGGSHRTLLYGQAVLFQHSYSGMYLCC LTASQSSTDKLAFDVGLQEDIAGETCWWTVHPASRQRSEGEKVRVGDDLILVNVSSERYL HMSFGTVFDNRSLSDSLIVNAAFQQTLWSVAPICSGGGVAQGYLKGGDTLRLLHSHSDAC LTVPSSEQGEELQRMMHYETGSVSSHAHSLWRLEILRVVWSGRHTCWGQPFRLCHVTTGR YLGLTEEKGLQLIDRDKADIDTTSFCFRSSKEKTDSGMKTGADGMGIPEIKYGDSMCYVQ HVDSGLWLTYQSTDAKSSHMRLTQRKAILHSEGHMDDGLTLSRSQREESHTARLIRSAIL LFTRFIRKLDGCSHHGTLPHVTLSMETVMCSLQDLIKYFQPPLDELGHEAKQNIMTAVKS RQNLFQEEGVIVLVLDCIDRLHQYSSSSHFAEAVQCEKGEEWETILSRFYELLAALIRGN RVNCAHFSGSLDWLISRLDRIEASSGALEVLHCILVESPEALNVIKEGHINSIISFLDQH GCNYKVLEVLCSLCVCNGVAVRSNQNHICDNLLSDRDLLLQTRLVNQVTSVRPNIFLAMG DDSAQPRRWYYELVVDHVDPFLTPEPTHLRVGWACTEGFYPRPTGGDGWGGNGVGDDLCS YGFDGLHLWSGCVGRRVNSPSPHLLKKDDVVSCCLDLTTPCISYRVNGLPVQGMLENFSA YGLLHPVVSFSAGVKFRFLFGGRHGEFRFLPPPSFAPCTEALLPRVKLKVQPCWKHILDY REGIKVLIGPSVPVTPVTFTPTPVDISKIDLPLQLEDIREKMAENIHELWVMDKMDLGWT HGTVRDESKRHDPCIVEFSKLPEQERNHNLQVAQDTLRTLTALGFHIGLTDDNAVERVKY MRLATKYEQPGGYRPAPVDLSQVTLSLSHEDMVNMLAENDHNVWARERIKQGWTYGPQQD VKAKRSPYLVPYSLLDERSKRVGRESVREAVCTLLAYGYSLEPLNQEQITSSNARLFSAE KYTVFRPDKSYAVTQGKWYFEFEVLTAGKMRVGWARPGCCPDKELGSDDQAYVFDGSEAQ WYHQGGELLGRPWQRGDVVGCLVDMDECTMVVTLNGEVLFNDRGSELAAKDFDIRDGVLP VVSVAVNQVGRLNLGRHMDSLQYFAVCGQQEGFKPFAVNMARDPSLWMSWGRPHFTPILP DDHNFKVTKTSGSVESVSSLRVSQQLFAHCGGGSEMGFYRLSMSLGCAAVLTSPAANVLP VAANSPAPSSHGRKEQEEVDSDFEVLMKSAHSFAGSRDELNHKDHSQDKTSRLKQRFLLK RTKPGLVSSNSSARLLEDVVVDKEICDHLIQSSRYYYSVRVLPGQEPFNVWVGWVTSDFH QYDMTFDTDYVNTVTVTLGDDGGKVQESVKRCSCYMVCAGEATGLSQSRRSAGLEIGCLI DTATGLLFFTSSGVEMATFYQVEASTKLFPAVFVKPTTSSMFQFQLGCIKNVMPLSTGLL RSQSRNATPQCPPRIQVQHLTPVSWTRVPDCALQVLVDRPDEHHGWSVQCSEPLQVMTLH IPDENRCVDILELSELDDLLKFHHHTLLLYCSLCTLGNTRVCHSLCSYVDQSQILHAIQN PNLPGPIRSAFYQLLTEVYLSSHTSACLMMNHEYIVPMTDQTRQVTLYPSPANGGQLPAC IPSTSLSTSLKPQMHFSTPCFVTSDGIEAGDAVKIVYKDSPEIPLDILKCLTMEMLIEGV WAVDQGVRDPVGGSIELLLVPLIKLFYTLLVMGVFGNKDLGIVLSLIEPGVFSIDAKTPE EEEEEEAIYANEIGWKNSNKTEYDTPSQGLLQMKLPEAVKLELCHLLSYLCDSQVRHRVE AVVAFSDTLVGQLQENQRYRYNQVMQALNMSAALTARKTKEFRSPPQEQINMLLNFREDE QQEHCPCPVKIQQLLRDFHHLLSTHCGIELDSESEDEEDAEMPVKDWLLSLVVRAFEVRK SSTQVEESRPRSAKSLKKLISETMVRWTEECEIEDPELVRAVFSLLHRQCQGLGGQMEGP LCRAYTISQASVEDTMMLLSSLAQIRSLLSVRMGKEEEKLTIRRLGDIMNNKVFYQHPNL MRVLGMHETVMEVMVNVLGEGESKEITFPKMVASCCRFLCYFCRISRHNQGALFDHLSYL LENSSVGLASPSMRGATPLDVAAASVMDNNELALALKEPDLEKVVQYLAGCGLQSCPLLL EKGYPDIGWNPVEGERYLDYLRFAVFCNGESVEENAYVVLRLLIRRPECFGPALRGDGGN GLLAAMEEAIKISEDLSMDGPCTQDIVQDHDDDDLVHMGHAIMSFYSALIDLLGRCAPEM HLIQGGKGEAIRIRAILRSLVPIQELEGVISISFQVPSVSKDGVVVESELSTVFCPDHKA AMVLFLDRVYGIENRHFFLRLLEVGFLPDLQAAVSLDTVDLGSTDMALALNRYLCTSVLP LLIKCSSLFCGLDDHTLLVDSFIQAVYSLSRGLSLTKAQRDIIEECLLAVCSKLQPSMMQ SLLRRLVLDVPHLTDHSKIPLRLLTSHYEERWKYLKTGGQGDQNSASEVELHLSTTLFWG VLKALAKRPYEPQLFKLCIRCLAAVAKALPPDHMDSVSPTERKSFMDTDGHFDPQPVDTS NISVPERLEFVVNKYAEHTHEKWSLDKFANGWVHGEQLCENSKVHPLLKPYRALAEKEKE AYRWAIKETIKSMLAFGWNIERTKEGDASGAHTCRRRISQSGQLSFEGASTFSPKPMDMS SITLSWEQCAMAEHLAENYHNAWAKRKKSELESKVGGHSMLVPYDTLTAKEKTKFREKAQ DILKFLQLNGYTVWRDRKTVDMDFPATANCFSYTLLQKLLRHTEEIQEHMLELEVMQARG QMSKGEKGPHQQQIHFFSKVILPLLEEFVKSHQMYFLSTSLCSSGNRAYATKKEKEMIAC FFCKLAALVRHRVSLFGNDASSVASCLHVLAQALDARMLMQFASDSIQASLHSFFEAAAA DLEMTVENLSVTLVSVPQGRSQQARGVAKVLSYTTSILLPTLTSLFQHLGNQNYGVDILV GGIQVSCYRIINSLYSLGNSSNVYMEGQKPAAGACLAALTGAFPLCYLEPALNQNNPYSI YNTQSVTEREDLGLPDEVVDACPLLPSLEQALSEVEKLAGAGAGARQSHYIHVTEVTLPM LCSYMSCWWPWGPEGQPGLPICSSITPKHVSDLLGHILRIIHNHVGTSQGDWMKQLAVFS QPIIFKACPELLKSHFLPLMEKLRKKAECVLLEEEKMKSEGWCASEAELKIQEKFTVLVR DLYAFYPLLIPFVDSYRASWLKVSNPEAEQLFSMVAEVFIFWAKSHNFKWEEQNYVVQNE INNLAFLVNNDKMSKYNHEKSMKRKGDRYSLQSSLIVASMKRLLPVGLRIFFPNEQNLIM SAKNSFTQNKTEDEVREQVFHGLLQSQVSNSLEQEQMSQSAAITDSQRIVDRIVGLARVL YYLDQVEHPQRSKKPLLHKVLSKRRKRAVVACLRMAPLYNLPRHRAVNLFLQGYNKSWIS AEDHSFEEKLVEDLARGRGVMELCGGNRGEEKEVKECAKPIDPLLQLITLFSRSALTESS NLGNDALYISYAAIMAKSCHRTDDNYEKQEVESFEVKEMEKQKLLYQQARLHLRGASEMV LQTISASKGAMGATIAPTLKLGIALLNGGNPTVQQKMLDYLGQKRDVGFFQSMAGLMRSC SVLDLNAFERQNKAEGLGMAMDEHSGDKVMPDKEITCDLFRFLQLLCEGHNSDFQNYLRT QSGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEHGQHNFSKAIEVSKQVFNTL TEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSRQIELLKELMDLQKDMVV FLLSMLEGNVVNGTIGKQMVDMLVESSGNVEMILRFFDMFLKLTDFTSSHDFREYDPDQK GQISRKEFQKAMENCNRFSLTETNFLLSCTETDKSEIVDYKAFVDRFHEPAKDIGFSIAV LLTNLSEHMPNDSRLRTFLELAECVLTYFQPYLGRIEILGSGKRIERVYFEISESSRTQW EKPQVKESKRQFIFEVINEGGEKEKMEMFVNFCEDTIFEMQLAAQISDTVGERYAGKEAN EKIMVEDENEKRGMCFMSQWWLLLTCLFSLKNLKSLMSMTLKDILLSTLCFARSVFMAQV RCICVVFRTIAYVLYLVFVNGGLIEGAKGMRISDLFGGILEPTLDEVMDVPSGVNRLRKY STCISSPGELREIGQVAAVTSQREVDVISDIFGLKVKKERGQYRLMTSDLTASLSDLFNI SPKTIASADFSQKHQRLQFKTHTATEDNQEDENISELENTNRGNESDKTTRNEKVEAGWR AKRSSNKSKEAESHHSDLREMINTCNLSLLNYFARNFYNMRLLALFVAFAINFILLFYKV TSLPASQEEDGVVTVVYSSGEDPPAAEYKTKGRDYFVLEESTGYMEPSLCFLAVAHTIIS FCCIIGYYCLKVPLVIFKREKEVARRLEFDGLYVTKQPPEEDIRGQWDRLVINTPSFPSN YWDKFVKRKIMDKYGKLYGCEKISELLGLEQAALDFSSERKERKWLKRETAWGTLFSSID MKYQIWKLGVVFTDHSFLYLAWYMAISVLGHYNSFFFAVHLLDIAMGFKTLRTILSSVTH NGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSDDKDTQDMKCNDMLTCYMFHMYVGVR AGGGIGDEIDDPAGDEFEVERIFFDITFFFFVIIILLAIIQGLIIDAFGELRDQQEQVKE DMETKCFICGVGSEYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWK MYQERCWEFFPVGDCFRKQYEDQL NT seq 14835 nt NT seq  +upstreamnt  +downstreamnt atgagagactctggagatggagatgatgaattccagtttctacggacgggagatgaggtg gttttgcagagtaccttaacatcccaggaggaacatgtgaagctctgtcttgctgcagag ggatttggcagcagactgtgcaggctggagtccacgtcaaactgcaagaatgtaccgcca gatttgtctgtatgtggctttgtccttgcccagtgtctctctgtccgagccctgcaggag atgctggcacacagccagcacctggctgcagagattgaagctggaggaagccatcgtacc cttctttatggccaggcagtgttattccaacattcgtacagtggcatgtatctatgctgc ttgactgcatctcagtcttcaacagacaaacttgcttttgatgttgggctgcaagaggat atagcaggtgagacatgttggtggactgtacacccagcatcccgacagaggtcagagggt gagaaggtgcgtgttggagatgaccttatactggtcaatgtgtcctcagaaaggtatctg cacatgtcctttggtactgtatttgacaacagaagcttgagtgacagcctgattgtgaat gcagccttccagcagactctctggagtgttgctcccatctgctctgggggtggagtcgct caaggatacctgaaggggggcgacacattacggctgctccacagccacagtgacgcatgc ctgacagttccctcctcagagcagggggaggagctgcagaggatgatgcattatgaaact ggatccgtctccagccatgcccactctctatggaggctcgagattctccgtgttgtttgg agtggtaggcatacatgctgggggcagcctttcagactgtgccatgttactactgggcgg tacctgggtctaacggaggagaaaggcctgcagctcatcgatcgggacaaagcggacatc gacacaacctccttctgtttccgttcctcgaaggagaagactgactctggcatgaagact ggtgctgatggcatggggatcccagagatcaagtatggagattccatgtgttatgtccag catgttgactctgggctgtggctcacctaccaatccactgacgccaagtcttcacacatg agattaactcagcgaaaggccattttgcacagtgagggtcatatggacgatgggctgaca ctgtctcgttctcagagggaagaatctcacactgccagactcattcggagtgctattctc ctttttactcgcttcatcaggaaactagatggatgtagccatcatggaaccctacctcat gtcaccctgtcgatggagactgtgatgtgcagtctgcaggatctaataaaatatttccag cctccactggacgagctgggccatgaagctaaacagaacatcatgacagctgtaaagagt cgccaaaacctgtttcaagaagagggtgtgatagttttggtcctcgactgtattgatcgc ttgcaccagtacagtagttcttctcactttgctgaagctgttcagtgtgagaagggagaa gagtgggagacgatcctcagccgtttctatgagctactggctgctttgatccgggggaac cgtgtgaactgtgcacatttctctggttctctggactggctgatcagcagactagaccga atagaggcctcttctggagccttggaggttctgcactgtatccttgtggaaagtcctgaa gcgctcaatgtcatcaaagaaggacacattaattcgatcatctcatttcttgaccagcat ggatgcaattataaggtactagaggtgctgtgctctctgtgtgtgtgcaatggtgtggca gtgcggtccaatcagaaccacatctgcgacaacctgctatcagacagagacttgctgctc caaacacgtctggttaatcaggtcaccagtgtgagaccaaatatcttcctggctatgggg gatgattcagctcagcctcggaggtggtactatgagctggttgtagatcacgttgacccc ttcctcacacctgagcccactcacctgcgtgttggttgggcttgcactgagggcttctac cccagacccacaggaggagacggctgggggggaaacggggtgggagacgacctctgctcc tatggctttgatgggcttcacctctggtctggctgtgtgggccgcagagtgaactctccc tcgccccacctgctgaaaaaggacgatgtggtcagctgctgtcttgacctcacaactccc tgcatctcctaccgggtcaatggtctacctgtgcagggcatgctggagaacttcagtgct tatggtcttcttcatcctgtggtcagcttctcagctggagtcaaatttcggtttctattt gggggaagacatggtgagtttcgcttcttaccaccacctagttttgctccatgcacagag gcactgctccctagagtcaagctgaaggtacagccatgttggaaacacatcttggattat agagaggggattaaagtgctcatcggcccctcagtacctgtcactccagttaccttcact ccaacgccagtggacatcagtaagatagatctgcccttacaacttgaggacatacgagaa aaaatggctgagaatatccatgaactgtgggtgatggacaagatggatcttggatggaca catggaactgttagagatgagagtaaaagacatgacccttgtattgtggagttctccaag ctgccggagcaggagaggaaccacaaccttcaggtagcccaggacacactcaggactctc actgctcttggattccacattggtttgactgatgacaatgctgtggagagagtcaaatac atgagactagccaccaagtatgagcagcccggtggctacagacctgccccagtggacttg agccaggttactctgagcttgtctcatgaggacatggttaacatgctggcagagaatgat cacaatgtgtgggccagagagcgtatcaaacagggatggacatatggaccccagcaggat gtgaaagccaagcggagtccttacctcgtgccatacagccttcttgatgaaaggagtaag agagtgggtagggagagtgttagagaggccgtctgtaccctgctggcctacggttacagc ctggaacccctcaaccaggaacagatcacatcatcaaatgcacgtctattctctgctgag aaatacacagtgttccgaccagataaatcctacgctgtgacccaggggaagtggtatttt gaatttgaggtactgacagcagggaagatgagagtgggctgggccagaccaggctgttgt ccagataaagaactcggctcagatgaccaggcatatgtctttgatggatctgaggctcag tggtaccaccagggcggcgaactgttaggccgtccatggcagagaggagatgtggtggga tgtttggtggacatggatgagtgcaccatggtggtcacgttgaatggagaagtgctgttc aatgacagaggatcagagctggctgcaaaggactttgatatcagagacggtgtcttgcca gtggtgagtgttgcagttaaccaggtggggaggctgaacctgggtcgccacatggactca ctgcagtactttgctgtgtgcggtcagcaggagggctttaagccatttgctgtcaacatg gccagagatccatctctgtggatgagttggggaagacctcactttactcccatactaccc gatgatcacaattttaaggtcactaaaaccagtggttcagtggagtctgtatccagcctg agggtttctcagcagttgtttgcacactgtggtggaggcagtgagatgggcttttaccgg ctcagcatgtctcttggctgtgctgctgtcctcacaagccctgcagcgaatgtgcttcca gtagcagccaacagccccgctccaagttcacatggaaggaaagagcaggaggaagtggac tctgactttgaagtgctgatgaagtcggctcacagctttgctggctcaagagacgagctc aaccataaggatcatagccaagacaaaacatccagattgaaacagcggttcttgctgaag aggactaaaccaggcctcgtcagcagcaactcatctgcacggcttctagaagatgttgta gttgacaaagagatctgtgaccacctcatccagagctctagatattactactcagtgaga gttctcccaggacaggagccatttaatgtgtgggtgggctgggtgacctctgactttcat caatatgacatgacatttgacacagactatgtcaacactgtgactgtcaccctgggagat gacggtggcaaagtccaggaaagcgtgaagcggtgcagctgttacatggtatgtgctgga gaagcaacaggtttgtctcagagccgaagaagtgcaggtttagaaattggctgtttgatc gacacggccactggtctgctcttcttcacctccagtggagtggagatggccaccttctat caagtggaagccagcacaaaactgtttcctgccgtttttgtcaagccaaccacgagcagc atgtttcaatttcaactgggatgcattaagaatgtgatgccgctgtcaacaggattgctt cgcagccaaagcagaaatgccactcctcagtgtcctccaaggattcaggttcagcatcta accccggtttcatggacaagagtaccagactgtgcattacaggtgttagtagatcgacca gatgaacatcatggctggagtgtccagtgctctgagcccctgcaagtcatgacccttcac atccctgatgaaaacaggtgtgtcgacattttggagttgtctgaactcgatgacctcttg aaatttcatcaccacacactcctcctctactgctctttgtgcacccttgggaacaccaga gtttgtcactccctctgcagttatgtggaccagtcccagatccttcatgccattcagaat cccaacctccctggcccaattcgatctgcattttaccagctccttactgaggtttacctc agcagccacacctcagcctgtctaatgatgaaccatgaatacattgtgcctatgacagac cagacccgacaggtcaccctttatcccagccctgctaatggtggtcaacttcctgcttgc attcccagcactagtcttagcacatctcttaaaccacaaatgcacttctcaaccccatgt tttgtgacaagtgatgggatagaagcaggcgatgcagttaaaatagtctacaaagacagc ccagaaatccccttggacatactaaagtgtctgaccatggagatgctgattgaaggagta tgggctgtggatcagggtgtgagggatcctgtaggaggcagcattgagcttctgcttgtt cccttaattaaactgttctatactctgctggtaatgggtgtatttggtaataaagatctc ggcatagttttgagtctgatagagcctggagttttctccatagatgctaaaacccctgag gaggaagaggaagaagaagcaatttatgctaatgaaataggatggaaaaacagcaacaag acagaatatgacactccttcacaaggactccttcagatgaagcttccagaagctgtcaaa cttgagctctgccatttgttgtcctatctgtgtgatagccaagtgcgccacagggtggag gctgtggttgccttctctgacactttggtggggcagctgcaggagaaccaacgttatcgc tacaaccaagtcatgcaggcactcaacatgtctgctgccttaactgcacggaaaaccaag gagttccgctcccctccacaggaacagatcaacatgctgctgaacttcagagaggatgag cagcaggagcattgtccatgtccagtgaaaatccagcagctgctccgagactttcatcac ctcctgagcacacactgtggcattgaattggacagtgagtcagaggatgaggaggatgct gagatgccagtaaaagattggctgctcagtctagtggtgagagcctttgaagtgaggaag tcttccacacaggtagaggagagtagaccgcggagtgcgaagtccctcaaaaagctgatt tctgaaacaatggtgcgctggactgaagagtgtgagatagaggaccctgaacttgttaga gcggtcttctcattgcttcaccgccagtgtcagggccttgggggtcagatggaaggacca ctctgcagagcctatacaatcagccaggcttctgtggaagacacgatgatgctactgtcc tccctggctcaaatccgctctctccttagtgtccgcatggggaaagaggaggagaaactg acgatcaggaggcttggagacatcatgaataataaagttttctaccaacaccccaaccta atgagggtattggggatgcatgagaccgtgatggaggtgatggttaatgttctcggagaa ggggaatcgaaggagattacatttcccaagatggtggccagctgttgtcgattcctttgt tacttttgtcgcatcagccgtcacaatcagggagcactgtttgaccatctcagctacctt ttggaaaacagcagtgttggactggcttcaccgtccatgcgtggagccactcctctagat gtggcagcagcctctgtgatggataataatgaactggccctagcactaaaggaacctgac ctagagaaggtcgtacagtatctggctggctgtggtctacagagctgcccgttgctactg gagaaaggctaccccgatattggatggaacccggtggagggcgagcgctacttggattac ctacgttttgctgttttctgcaatggtgagagtgtggaggaaaatgcctatgtggtgttg agattgctgattcgtcggcctgagtgttttggccctgctctgcgaggtgatggcgggaac ggccttctagctgccatggaggaggccatcaagatctctgaggacctgtctatggacgga ccctgcacacaagatattgttcaggaccacgatgatgacgaccttgttcacatgggacat gccatcatgagcttctactcagcccttattgacttgctggggcgctgtgctccagagatg catttaattcaaggaggcaaaggagaagccatccgcatccgcgccattctccggtcactc gtccccattcaggagcttgagggagtcatcagtatctcctttcaagtcccttcagtgtca aaagatggtgtggtggttgagtctgagctgtctacagttttctgcccagaccacaaagca gctatggttctgttccttgaccgggtttatggcatcgagaacaggcactttttcctccgg ctgctagaagttggttttctgcctgaccttcaggctgccgtctcacttgacactgtggat ttgggatccactgacatggctctggctctcaacagatacttgtgtacatctgtgctcccc ctgctcatcaaatgttcatctctcttctgtggtttggacgaccataccttgttggtggat tctttcattcaggcagtctacagcctctccagaggtctcagtttgaccaaggctcagaga gacattatagaggagtgtttgttggctgtgtgcagtaaactgcaaccatccatgatgcag tctcttctacgtcgccttgtccttgatgttcctcatctcacagaccacagcaagatacct ctaaggctcttgaccagtcactatgaggagaggtggaagtacttgaaaaccggtgggcag ggtgaccagaattcagcctctgaagtggagctgcacctgtccactacattgttctgggga gtgttaaaggctttggcaaaaaggccctatgagcctcagttattcaagctttgtatccgg tgtctggctgcagtggccaaggcccttcctcctgaccacatggactccgtgtctccaact gagagaaaatctttcatggacacagatggacactttgacccccagcctgtcgatacctcc aacatatcggtaccagagagactggagtttgtagtgaacaagtatgcagagcatactcat gagaagtggtcactggacaagtttgcaaacggctgggttcacggggaacagctctgcgag aacagcaaggttcaccctctcctgaagccttacagggctctggctgagaaggagaaggaa gcataccggtgggctattaaagagacaataaagagcatgctggcctttggatggaatata gagaggactaaagaaggagatgcgtctggcgcacatacctgtaggcggagaatctctcag tctggacagttgtcttttgaaggagcatcaacattcagccctaaaccaatggacatgagc agcatcaccttatcatgggagcagtgtgctatggctgaacatttagctgaaaactatcac aatgcctgggctaagaggaagaaatccgaacttgaaagtaaagtgggtggccattcaatg cttgtaccttatgacacactgactgcaaaggagaagaccaaattcagagaaaaagcccag gacatccttaagtttcttcagctcaatggctacactgtgtggagggatcggaagactgtg gacatggactttccagccacagccaactgcttcagctacaccctccttcagaagctgctg cgtcacactgaggagattcaagagcatatgttggagctggaggtgatgcaagccagagga cagatgtctaaaggggagaaaggcccacaccagcaacaaatacatttcttttccaaggtc atccttcctcttctggaagaatttgtgaaaagccaccaaatgtatttcctgtccacttct ctgtgctcgagtggaaacagagcctatgccacaaaaaaagaaaaggagatgattgcttgc ttcttttgcaaacttgctgccttagtgagacacagagtctcactctttggaaatgacgct tcatcagttgcaagctgcctccacgttttggctcaagctctggatgccaggatgttgatg cagttcgcttcagattctatccaagcatctctgcactcattctttgaggcagcagcagct gatctggagatgaccgtggaaaacctgtctgtcacgttggtctctgtgcctcagggcagg agtcaacaagctagaggagtagccaaggttcttagctacacgacctccatacttcttccc actcttacttccctctttcagcatcttggcaaccagaactatggagtagatatcctggtg ggtggcatccaggtgtcctgttacagaatcatcaacagcctctactcacttggcaacagt agcaacgtctacatggaggggcaaaagccagcagcaggtgcgtgtctggcagccctgact ggtgcttttcctctttgttacctggagccagccctcaatcaaaacaacccttattccatt tacaacacccagagtgttactgagagagaggacctggggctaccagatgaggtggtggat gcgtgtcctctgctgccttctctagaacaggccctgagtgaagtggagaagttggcaggt gctggagctggagctcgccagtcccactatatccatgtcactgaggtcaccttgcccatg ctgtgcagctatatgtcctgttggtggccctggggcccagagggccagccgggcctccca atctgctcctccatcactcctaagcatgtcagtgacctacttggccacatccttcgcatc atccacaaccatgtgggcactagccagggtgactggatgaagcagctggcagtattttct cagccaattatatttaaagcttgccctgagctgctaaagagccatttcttgccattgatg gagaagttgaggaagaaagcggagtgtgtgctacttgaggaggagaagatgaaatcggag ggttggtgtgcctcagaggcggagctgaagatacaggagaagttcactgtgctggtgcga gacctctatgccttctatccccttctcattccattcgtggattcttatcgagccagctgg ttgaaagtgtcaaaccctgaggctgagcagctgttcagcatggtggcagaggtctttata ttctgggccaaatctcataatttcaaatgggaggaacaaaactatgtggtacagaatgaa attaacaacttggccttcttggtcaataatgacaaaatgtccaagtacaaccatgagaag agtatgaaaagaaagggggaccgatattccttgcaatcctctcttattgtggcttccatg aagagactgcttcccgttggccttaggattttttttccaaatgagcagaaccttatcatg tcggcaaagaacagcttcactcagaacaagaccgaagatgaggttcgtgagcaagttttc catggacttcttcagagtcaggtatcaaacagcttggagcaggaacaaatgagccagtca gctgccatcactgactcccaaaggattgtagacaggattgtgggattagctcgtgttctt tattacctggaccaggtggaacacccacagagaagtaaaaaaccattgttgcacaaagtc ctgtctaaacggaggaaacgagcagttgtggcctgcctaaggatggctcctctctacaac cttcccaggcacagagctgtcaacctgttcctccaaggctacaacaaatcctggatatca gctgaggaccacagcttcgaggagaagcttgtggaggatttagctagaggacgaggagtg atggagctgtgtggaggcaacagaggagaagaaaaggaggtgaaagaatgtgccaaacca atcgatccccttctacaactcattacactcttcagtcgaagcgcccttacagaaagcagt aaccttggaaatgacgctctgtatatatcctacgctgctataatggccaagagttgccat agaacggatgataactacgagaaacaggaggtggaaagctttgaagtgaaagaaatggag aagcagaagttgctgtaccagcaggccaggttgcatcttcgtggagcttctgagatggtc cttcaaactatcagtgccagcaaaggagccatgggcgccacgattgctcctacactgaag ctgggcattgctcttctcaatggaggaaatcccacagttcaacagaaaatgctggattat cttggacagaagagagacgttggcttttttcagagcatggcaggactcatgcggtcatgt agtgttctggatttaaatgcatttgagaggcagaacaaagcagaaggattaggcatggcc atggacgagcactcaggagacaaggtgatgcctgacaaagagataacctgtgacctattt cgctttctacagctgctctgcgaaggacacaactcagatttccagaattacttgagaaca caatctggcaacaacaccactgtgaacatcattatttcgactgtggactatttactgaga gtgcaggaatctatcagtgacttctactggtactactcgggcaaagatgtgattgatgaa catggccagcacaacttctccaaggccattgaagtatccaaacaggtcttcaacacactt actgagtacatacagggaccatgtactgggaaccagcagagtcttgctcacagtcgcctt tgggatgctgttgtgggattccttcatgtctttgcccacatgcagatgaagctgtcacag gattcgaggcaaattgagctcctgaaagagctgatggatttacaaaaggacatggttgtg tttttgctttcaatgttggaaggtaatgttgtcaatgggacaattggaaagcagatggtg gacatgctggtggaatcatcaggcaatgttgagatgatcctcaggttttttgacatgttc ctcaagcttacagacttcacctcctcacatgacttcagagagtacgaccctgatcagaag ggccagatatccaggaaggagtttcagaaagccatggaaaactgcaatcgtttctccctc actgagaccaatttcctcctctcatgcacagagactgataaaagtgaaatcgtagattac aaggcctttgtggatcgcttccatgagccggccaaagacatcggcttcagcattgctgtt ctcctcaccaatttatccgaacacatgcctaacgactcaagactgcggactttcttggag ctagcagagtgcgtcttaacttattttcagccatacttaggacgcattgagatcctgggc agcgggaaacgaattgaacgcgtctactttgagatcagtgaatccagccgcacacagtgg gagaagccgcaggtgaaagagtctaagaggcagttcatttttgaggtcatcaatgagggt ggagagaaggagaaaatggagatgtttgtcaatttctgtgaggacaccatctttgagatg caacttgcagcgcagatatctgacactgtgggagagaggtatgctggaaaagaagcaaac gaaaagatcatggttgaagatgaaaatgaaaaaaggggaatgtgtttcatgtctcaatgg tggctgctgctgacatgtcttttttctttgaaaaacctcaagtcgttaatgagtatgact ctgaaggacatccttttgtcaactctttgctttgcaagatcagtttttatggctcaggtg cggtgcatttgtgttgtatttcgcaccattgcatatgttctatatctggtctttgtcaat ggtggtctcatagaaggagccaaaggcatgagaatatcggacttgtttggtggtatcctt gagccaactcttgatgaggtcatggatgtgccaagtggtgtgaatcggctgagaaagtac tcgacctgtatctcctccccgggagaattgagggagattgggcaggtggcagctgtgacc tcccagagggaggtggatgtaatatcagacatatttggcctgaaagtgaagaaggagaga ggtcaatacagacttatgacatcagacctcactgccagtctgagtgacctgttcaacata agccccaagacaattgcctctgctgatttttctcaaaagcatcagcggctgcagtttaag acccacactgccacagaggacaatcaagaagatgagaacatttctgaactggagaacaca aacagagggaatgaatctgataagacaaccaggaatgagaaagttgaggcaggatggaga gcaaagagatcctctaataagtcaaaggaagcagagagccatcattctgatcttagggag atgataaacacttgcaacttgagcctgctgaactactttgcaaggaatttttataacatg cgtttattggctctctttgtggcatttgcaatcaacttcatcctcctcttctacaaggta acatcgttacctgcatcacaagaagaggatggagtggtcacagttgtttacagctcagga gaggacccccctgctgctgaatacaaaacaaagggcagagattattttgtgctggaggag agcactggatacatggagccatctctctgcttcttagctgtcgctcacacaatcatctcc ttctgttgtattattggttattactgcctaaaggtacctttggtgattttcaaacgtgag aaggaagtggcacgacggctggagtttgatggactgtacgtgacaaaacagccccccgag gaggatatcagagggcaatgggaccgactggtcatcaatacaccatcatttccaagtaat tactgggataaatttgtgaaaagaaagataatggataagtatggtaagctttatggctgt gagaaaatcagtgaactcctgggattggaacaggctgctttagacttcagctctgagaga aaagaaaggaagtggctcaagagagagaccgcctggggtacactattttcatccattgac atgaagtatcaaatctggaaacttggagttgtgttcactgaccactccttcttgtacttg gcttggtacatggccatatcagttctgggtcattataacagcttcttctttgctgttcac ctgttggacatcgccatgggcttcaagacgcttcgtaccatcctttcctcagtcacgcac aatgggaaacagttggtcctgactgtcggcctgttggcagttgtggtgtatttgtacact gttgtggccttcaacttcttcaggaaattttacaacaaaagcgacgacaaagacactcaa gacatgaagtgcaatgacatgcttacttgttacatgttccacatgtatgtgggagtgcgt gcgggcggaggcattggtgatgagatcgatgaccccgctggagatgagtttgaagtggag cgtattttctttgacatcacctttttcttctttgtcatcattattcttctggccatcatt caaggcttgataatcgatgccttcggggaactccgtgaccaacaggaacaggtgaaggag gatatggagaccaaatgttttatatgtggagttggaagtgaatattttgatacggtccct catggctttgagacacacactctgcaggagcacaacttggccaactatctattttttctg atgtacctcattaacaaggacgaaactgaacacacagggcaggaatcctatgtgtggaaa atgtaccaggagcgttgctgggaattctttcctgtgggagattgtttccgtaagcaatat gaggatcaactatag

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