Streptomyces seoulensis: D0Z67_07270
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Entry
D0Z67_07270 CDS
T07029
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sseo
Streptomyces seoulensis
Pathway
sseo00300
Lysine biosynthesis
sseo00550
Peptidoglycan biosynthesis
sseo01100
Metabolic pathways
sseo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sseo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
D0Z67_07270 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
D0Z67_07270 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
D0Z67_07270 (murF)
Enzymes [BR:
sseo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
D0Z67_07270 (murF)
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Ortholog
Paralog
Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DHHA1
DUF2126
DUF561
RPAP1_N
Motif
Other DBs
NCBI-ProteinID:
QBJ90126
UniProt:
A0A4V0ZZ77
LinkDB
All DBs
Position
complement(1545228..1546643)
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AA seq
471 aa
AA seq
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MIALSLAEIAAVTGGQTHDIPDTSVQVTGPVVRDSREVVPGTLFVAFVGERVDGHDFAAQ
VVEAGAVAVLASRPVGVPAIVVDDVQEALGALARHVVERLGATLVALTGSAGKTSTKDLI
AQVLGGKAPTVFTPGSLNNEIGLPLTALSATEETKFLVLEMGARGIGHIRYLAGLTPPKV
GLVLNVGSAHIGEFGGREQIAQAKGELVESLPPAAEGGAAILNADDPLVRAMASRTKAKV
ILFGESAEADVRAENVRLTDSGQPAFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSATEIATALSGAGTLSRWRMEVTERPDGVTIVNDAYNANPESVRAALRALVAMGKGRR
TWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGIEASWLQLGAYNEGSWGEESV
HVSDAQAAIDLLRKQLRPGDVVLVKASRSVGLERVAQALAEAGTEGEVAAR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagcagtcaccggcgggcagacgcacgacata
ccggacacgtccgtccaggtcaccggcccggtcgtccgggactcccgcgaggtggtgccc
ggcaccctgttcgtcgccttcgtcggcgagcgggtggacggccacgacttcgcggcccag
gtcgtcgaggccggcgcggtcgccgtactggcgtcgcgtcccgtcggcgtgcccgcgatc
gtcgtggacgacgtccaggaggccctcggcgccctcgcccgccatgtcgtcgaacggctc
ggcgcgaccctcgtcgcgctgaccggctcggccggcaagaccagcaccaaggacctcatc
gcccaggtgctcggcggcaaggcgccgaccgtgttcacgcccggctcgctcaacaacgag
atcgggctgccgctgaccgccctgtccgccaccgaggagacgaagttcctcgtgctggag
atgggcgcccggggcatcgggcacatccgctacctggccggactcaccccgcccaaggtc
gggttggtgctcaacgtgggcagcgcccacatcggcgagttcggcggccgggagcagatc
gcccaggccaagggcgagttggtggagagcctgcctccggcggcggaaggcggcgcggcg
atcctcaacgccgacgacccgctggtgcgcgcgatggcctcccgtaccaaggcgaaggtg
atccttttcggagagtcggccgaagcggacgtacgcgccgagaacgtacgactcacggac
agcggacagcccgccttcaggcttcacacaccctccggtgcaagcgatgtgaccatgcgc
ctgtacggtgagcatcacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgcaaccgagatcgcgaccgcgctctccggggcgggcaccctctcccgctgg
cgcatggaggtcaccgagcgccctgacggcgtgaccatcgtcaatgacgcctacaacgcc
aaccccgagtccgtgcgggccgccctcagggcgctcgtggccatgggcaaggggcgccgc
acgtgggcggtgctcggcaagatggccgagctgggggacgaggctctcgccgagcacgac
gcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcggtggcatc
gaagcctcctggctgcaactgggcgcatacaacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggcgatcgaccttttgcgcaagcagttgcgtccgggggac
gtcgtgctggtgaaggcgtcccggtcggtgggtctcgagcgggtcgcgcaggcgctcgcc
gaggccggcaccgagggtgaggtcgccgcccgatga
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