Streptomyces alfalfae: A7J05_35390
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Entry
A7J05_35390 CDS
T05110
Name
(GenBank) non-ribosomal peptide synthetase
Organism
ssia
Streptomyces alfalfae
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Condensation
AMP-binding
PP-binding
AMP-binding_C
Motif
Other DBs
NCBI-ProteinID:
APY90247
LinkDB
All DBs
Position
8270042..8290039
Genome browser
AA seq
6665 aa
AA seq
DB search
MTSSTPSNPSPDSSSGATGSARPSQTARPSRRDRAEALPEEMREALRRRLAGRAGGTATA
ARQGIPRADRDRPLPLSFAQQRLWFLDRLRPGDARYNSAVALRLTGAPDLEALGEALRTV
VARHEALRTTFEETDGRPAQRVHPAGPVPLPVRDAGDLDKELLAEYSRPFDLRNGPLLRA
LLLRESATSHVLLLTAHHIVTDGWSMGVVLDELCTAYDALARGAAPALPPVATQYPDFAV
WQRARLSGTRLEGELAHWKQRLAGAAAPELPLDRPRRGEEAGEGAVCSFTLPARLTARLR
DLAREQHTTLHTALVAAAQALLARWSGQDDITVGSLTPGRSRTDLERAVGFFVNTVVLRT
RVEAAGSFRELLGQAAETVGDAFAHGDTPFERIVEAVGAPREAGRNPLFDVLVLLHPDPP
AATSPRGLATTPVNVPRHAATFDLSVEFVPDGDALTGLLEYRTDLFDAATAERMAGQLTR
LVEGACAEPDRALDSLPLLSEEETRRLVHDWNPAPLPATDTTCPELYERRAAAAPDTLAL
VAGGERLDHATLNARANRLAHHLIARGAGPERLVALRLPRTADMIVAILAVWKSGAGYLP
LDPALPEDRIRFLLDDARPALVLDEPALRAVPEDSPDTDPTDAERRAPLLADHTAYVIYT
SGSTGRPKGVAVTHRAAAHLLAAHRAGFVAEAGGGPLRTALTASFSFDTSLEGVLLMADG
HPLHLVDETTRMDPAALVAYVVEHRVDFLDVTPSYLRQLLPAGLLTDPRHHPRVLMLGGE
AVGPALWRELAAHPDVVAHNFYGPTECTVDALSCRIDGGDRPLVGRPLPGVRAYVLDGRL
RPVPPGVGGELYLAGGQLARGYTGRPGLTAARFLPDPFGGPGERMYRTGDLARWTADGRL
DYLGRADDQVKVRGHRIEPGEIEAALLALPAVSAAAVVALPDPHGHARLAAYVVPAPGAP
RPVPADLRTALREVLPDALVPSSFTCLDALPLTTSGKLDRRALPAPESTPEEREFVAPRT
PGEEALAGIWAEVLGTARVGVTDNFFELGGDSILSMQAVSRARAAGLRINSQDVFRHQTV
ADLAAAASRRTASAPAPRRPHEDGPAPLTPVQEWFLATHGPLRHFAMSMLLDLPYDLDAQ
ALDRALHAVVARHPALRTRFTRTDDTWRQHPGTGPATGLLTRHDSATAPAEAAEAARAAL
DPATGALLRAALLPGGERPRLFLTAHHLAVDSVSWRVLLADLAHAYRRAAAGEDPLPEAE
HTPFADWARTLAERVRAGDLDDDLAHWTREAAQPRTPLPVDLPGAPLAGSVRTVRTRVDR
DTTEALLRRVPSAYRTQVNDVLLSALGRVLADWTDADRVTVALEGHGREEELDEGADLSR
TVGWFTTQYPVTLTPAGGDDWGATLKSVKEQLRAVPRRGLGYQALGHLGSPRPEARALGE
LPLPDVCFTYHGQWEASAGGDFAPVADVPGRDMDPDAPLDHLLDVSALVTDGELEITWHY
SDQVHREDTVQELASGLARALTAIAEHCARPGTGGRTPSDFPLARLDQAGVDRLAGDGRD
VEDLLPLTPLQEGMLFHRLVGGDDDVYVDQAALLLEGVSDPDALALAWQRVTDRTPALRT
SVVWEGVPVPLQVVHRRVEVPVVQLDWRELDAAERAERLERLRADDLARGLDLGAAPLMR
LTLVRLPDARLHLLWTSHHLILDGWSLAQVLTEVSDEYAALTTGAEPRPPARRPFGDYVR
WLAGQDTGAAHAHWRAVLDGFTTPTPLLVDRARRPGHETRSADVHTAALSDEVSARLART
ARTAGLTLGTVVQGAWALLLSRYSAESDVLFGTTVSGRPDDLPGADAMVGMFINTLPTRV
RVDGDRTSTDWLRELQEEQAQARRFSAVSLAELTSLSGVPAGSPLFDSMVAFENYPFDEA
RSATTGIRLTDVSSRDATNFPLVLRAYQGERFGFDLAYDPELFDATTVRGLADRFCLLLT
ELADDPDRPVRALAWTTAEERRRMLTDWNGAASGRPADTLDALFAAQAARTPDAEALTCG
DERLDYATLDTRASRLAHRLAELGAGPETFVALTLPRSADLVVAVLAVLKTGAAYLPVDP
RLPAERVRHMLADAGPVALVTTRQDETGTDVPRLLLDDPQVRADLARRPAAGPARRALPE
SPAYAIYTSGSTGRPKGVVVPHANVVRLFTRTRHWFDFGTDDVWTLFHSYAFDFSVWELW
GPLLHGGRLVVVPEDTARSPEDFLRLLADERVTVLNQTPSAFYPLIRADAELPDAGDRLA
LRTVIFGGEALDVGRLADWYARHPDTAPRLVNMYGITETTVHVTHAPLDRAAARPGAASP
IGTGIPDLRLYVLDGTLQPVPPGAVGELFVAGEGLARGYLNRPGLTAARFLADPFGRPGT
RMYRTGDRARWRADGTLEYLGRADQQVKIRGYRIEPGEIEAALHGHPGVGAAAVGVYEDT
AGTRRLVAHVVGTGTGAGEGGECAAPPSAAELRAHLEGLLPAHMVPAAYVPLDALPLTAN
GKLDRRALPAPGPDGFAADGTRTPPRTPAERLVASAWTDVLDTGEVGADDDFFALGGDSI
LAVRVTSRLRAAFGAEVSPRLLFTHPVLRDLAAALGEPGGADTADAIPATAPGAPAPLSY
AQQRLWFLDQFEPGGTEFTTLSVLRLRGPLDQDALRAALDGVVARHEALRTTFTEHEGQA
RQIVHPPRPVDLPVTDLADATALDALVDLAAATPFDLATGPLLRARLARSAPDEHVLVLA
VHHIVTDGWSVGVLARDLGELYAAALEDRRPDLPDLPVRYSDYAAWQRSRADRAETELAH
WRRALDGVSPLELPTDRPRPAVRTRDGALVTFTLPAALTERLRERAREADATLYMTLVTA
CQTLLARWAGQEDVTVGTVTAGRDRAELHDVVGMFVNTLVLRARVRPGVPFLNLLAEVRD
TVLAAFAHQEVPFERVVDALQPERDTSRTPLFQVMVALHNLGAEPLRLPGLTAEPVTPPV
RTATYDLAFDFVEGDGGLTGHLEYNTGLFDTGTAERLAARLRVLLEAVAADPGQSVDTLP
LMTDDERQQVLRHGEGVRLPEPDTTFPALFEAQAARTPAHTALAARDTTLDFAALNQRAN
RLAHHLIARGAGPEDVVAVRLPRTSDLMAAVLAVLKAGATLLFLDPELPAERQDVLLGDA
RPHTVLTGLDAVPWDGLPAHDPTDADRVRPLLPRHPAYIIYTSGSTGRPKGVVVEHRNLV
NLCHDHRAGLLAPHTAGGQRLRAALSASFSFDTSWEGPLLLALGHEVHLIDEDVRLDPRA
FCAHVVEHRLDWVNVTPTYLRELTAADLLAADRHRPRLLLVGGEALTPADWRDLVRAEQD
LGVAVYNMYGPTETTVDAVYGRCAGQPHRPLIGRPGANLRAHVLDAALRPVPPGTPGELY
LAGAQVARGYLNRPGLTAARFTADPFGAPGERMYRTGDRVRWDRDGRLEFLGRTDEQVKI
RGFRIEPGEIEAALLTHPDIADAAVAVRENAGRPMLVGYVVPATGRVPSPDALRLALRRT
LPDHMVPAAFVPLARVPRTTSGKTDRRALPAPPAQPESGTPHVAPRAGTEEILAGIWAQV
LGVARVGARDNFFALGGDSILSIQIVSRARQAGLVLATKDVFRHQTVAELALRVQESAPP
PDTEEEPAEAPLTPIQHWYLEGRAPGQRLRFTMTQRLELAPDTAAATLRTAVDALVGHHA
ALRTRFRRTADGWRQDVLPEAPDGVFTRHDVSGLDDTALEDEVQRLTGEAQAALDPTAGR
VTRVLFFDRGPGRPGQLVVTAHHLVIDGVSWRILLADLETAQRAAALGRPVELPPTGTSY
GRWAARLERHARSGALDTDLPYWTDTATAPAALPAGRPGPNTHATAATRTVTLDAETTGA
LLREVPRAYRTQVNDVLLSALGRTLARWCGRDSVLLGVEGHGREELFADVDLSRTVGWFT
AEFPLALRVAPDAGWHDTLRAVKEQLRAVPLHGLSHGALRHLVPGSPLASGPAPQVGFNY
HGQWDTDTTDGLFRRALPPAGLDTDPDEPRPYLLDITGVVQRGRLELGFTYPAAVYDQAT
VDRLAQDTLTALREIVAHCAHPDAGGRTPSDFPLAGLGQEQLDRLLGTGRDAEDVLPLTP
LQSGMLFHGLVDTEHAYFDRTAVRLSGVADPQVFAAAWQQVADRTPALRTSVHWQGLPHP
VQVVHRRAELPVRHLDWRALAPAERAAATERLLAEDRAAGLDLAKAPLTRLTLAALPGDE
VLLVWSTHHIVLDGWSTGQLLTEVCERYAALTGGPDQAPPVRRPFADFLHWLREQDETAA
EGFWADALAGFTARTPLPYDSNPAEAHRARSTQAVHHELDADVSRRLRETAARAGVTVNT
VVEGAWALLLARSGGRDDVVFGTTVSGRPAELPGVEGMIGMFINTVPTRARVPAAGPVST
WLRELQERQSEARRFDFLALPRIQAVSEVPSGQALFDSMVVFENYPVDESATARTGVRVE
EVRADDATTFPWCLRAHLAEHLGYDLAYDPELFDAATAERAAHRLAGLLTALADGFDTDL
AELDVLAPADRALLAAWNTTARPAAPRSPVDLFTEQTTRTPDAIAVDDGENRLTYRELHD
WARALADRLRAAGLASEDRVALRLDRSAELVVAQLAVLMAGGAYVPVDARAPEERRRTLL
AQAGATLRLTATEVTAARTGTTETSARPAADPDQLAYVMFTSGSTGLPKAVAVRHRDVAA
LATDSRFTGGVCDRVLLHSPVAFDAATFEVWAPLLNGGRVVVAPDGDLDGAALRRLAADG
GLTAMWLTAGLFRLLAQDAPDCFRGLTQVWTGGDVVPAQAVRRVLDACPGLTVVDGYGPT
ETTTFATSFALTDPAAVPATIPVGRPLDDMRALILDTRLRPVPPGCPGELYLAGEGVARG
YLGRPGETAARFPADPLGPAGARMYRTGDLARRRPDGAVEFLGRADDQVKIRGFRVEPGE
VEAAIAAHPDVVDVAVLAREDRPGARRLVAYVVGPAGRNGEALRSFAARTLPDYLVPTTV
VPLAALPLSRNGKVDRAALPVPEAAPGRGRTEPRTEAERRTADVFAEVLAGETPGVEDDF
FQLGGDSILSIRLASRLAEAFGTDVSPRAVFTHSTPAALARLIGERRGSGRPALVPRARD
AVAPMSHAQQRLYFLHEFEPGGAEYVTALALRLCGTLDTDALRAALGAVVARHESLRTTF
DSVDGHGIQRVHPPRDVPLPVHDLSGLGAGEREPAVRRLLAEERLRPFDLREGPLLRAGL
LRLADDEHILTLALHHIVTDGWSTAVLLGDLAHFYRAERGVPQAELAPLPVQYADYAHWQ
RTTGDTEADEHLAYWKEHLADTPPLELPTDRPRPPVRTSAGATTRLVVPATTAGRLTRLA
RDHGTTLFTALVAAAQSYLARLSGGGDIAVGTVNAGRDRPETQALVGFFVNTLVLRSRAE
AGQPFTEFLGDVRRTVLDAFAHQDVPFERVVDEVQPVRDTSRSPLFQVMVVLQNTPTVDL
DLPGLDVTDVEPESEQAAFDLTLEFAETGSGELHALLTYNTDLFEAATAERMAGQLGAWL
HAIAEDPRRPLGALPLTTAGETASLLEQGRGAFRPIPESTLPALFEQQAARTPDAVALID
GERELTYAETDRAANRLAHRLLRDGVGPERVVALALPRSAAAVVAQLAVAKAGGAFLPVD
PDYPPQRREFMLADAGAELILDDPAQVWAAEGPTTAPTDADRTSTLTPAHPAYVIYTSGS
TGTPKGVVVTHRGLASFAAAAAEQYAAGPGDRVLQFASPSFDASILELCVSLLSGATLVT
GEEGPLVGERLAEVLAERRVSHTLIPPAALATLPARTAADLPHLRTLIVGAEACPADLVD
TWAPGRRMVNSYGPTEATVVATWTGPLTPGAGAPPIGRPSGGTRVYVLDTALRPVPPGVT
GELHIAGPGLARGYLGRPGLTAQRFLPDPFGAPGERMYRTGDLVRWSADGQLRYAGRADD
QVKLRGFRIEPGEIESALRRSPLVRDAAVAVRAGDGPGTPSRLVAYVVPEPPAATHTRPE
PSGTGSPGTDSSATALSTGELRLHLAETLPPHMVPSVFVPLDRLPLSPNGKIDRRALPAP
GPARAMDGPQTAPRTDTERRIARIWADVLGLAEVGAEGNFFALGGDSILSMQVVSRMRRD
GLHVATRDLFTHQTVAELATVVRTAPRRSAEGPVTGEVPLTPIQEWFLTTPRAAHHHFNQ
SALFELDGRPDPRALHTALDALIEHHDALRMRFTRDEHGWQQYNPPPADGDDAPDILVRH
DLSGLSPEDADAAMAKAADALHVSFDLARGPHLRAALFTGDPDRPAYLLLIAHHLVVDAV
SWRVLRDDLETAYRQALQGEPVALGERGTSFRDWSRRLAAHVAEGGLDHELPHWEQTVGA
EPTPADPAAATGDGPAATVSVELDEEDTTALLRSAPTAYRTRVNDVLLTALALALARWTG
HDRVRLDLEGHGREDLLDGVDLSRTVGWFTTVHPVALHVPDPGGLGPDRDWRSLVKSVRR
QMRAVPGNGIGYGALRTFGPPEVRERLGAQAHSQVVFNYLGQWDARPETADGGLVRAEHG
SFGQDHDLRDPGSHPVEVVGAVQHGRLAFTWHHRPGLHDTAAVRRAAEDFAEALRLLARD
ARGGR
NT seq
19998 nt
NT seq
+upstream
nt +downstream
nt
atgacgtcttcgaccccttcgaacccctctcccgactcctcctcgggcgccaccggctcc
gcacgtccctcccagaccgcccgcccttcgcgccgcgaccgtgccgaagccctgcccgag
gagatgcgggaggcgctgcggcggcggctcgcggggcgggccggcggcaccgccacggcc
gcccggcagggcatcccgcgcgccgaccgggaccgcccgctgccgctgtccttcgcgcag
cagcgcctgtggttcctcgaccggctgcggcccggcgacgcccgctacaacagcgcggtc
gccctccgcctcaccggcgcgccggacctggaggcgctgggcgaggcgctgaggaccgtc
gtggcccggcacgaggcgctgcgcaccaccttcgaggagaccgacggccgtccggcgcag
cgcgtccaccccgcgggcccggtgccgctgccggtccgcgacgcgggcgacctcgacaag
gagctcctcgcggagtactcccggcccttcgacctgcgcaacggcccactcctccgcgcc
ctgctgctgcgtgagtccgccacctcccacgtcctgctcctcacggcccatcacatcgtc
accgacggctggtccatgggcgtcgtcctggacgagctgtgcaccgcctacgacgccctc
gcgcgcggcgcggcgcccgccctgccgcccgtcgccacgcagtacccggacttcgcggtg
tggcagcgcgcccgcctctcgggcacgcgcctcgaaggcgaactcgcccactggaagcag
cgcctggccggggcggcggcgcccgagctgcccctggaccggccgcggcgcggcgaggag
gcgggcgagggcgccgtgtgctccttcaccctcccggctcggctgaccgcgcgcctgcgc
gacctggccagagagcagcacaccaccctgcacaccgccctcgtcgccgccgcccaggcg
ctcctcgcccgctggtccgggcaggacgacatcaccgtcggctccctcacgcccggccgc
tcccgcaccgacctggaacgggccgtcggattcttcgtgaacaccgtggtcctgcgcacc
cgcgtggaggcggccgggtccttccgcgaactgctcggacaggcggccgagacggtgggc
gacgccttcgcccacggcgacaccccgttcgaacggatcgtggaggcggtgggcgcgccc
cgcgaagccggccgcaacccgctgttcgacgtgctggtcctgctgcaccccgacccgccc
gccgcgacctccccgcgcggcctcgccacgaccccggtcaacgtgccccggcacgcggcc
accttcgacctgagcgtcgagttcgtgccggacggcgacgccctgaccggactgctcgaa
taccgcaccgacctgttcgacgcggccacggccgagcggatggccggacaactgacacgc
ctcgtcgagggcgcctgcgccgagccggaccgggcgctggacagcctgcccctgctctcc
gaggaggagacccggcgcctcgtccacgactggaaccccgccccgctccccgccacggac
accacctgccccgagctgtacgaacgccgggcggccgcggcccccgacaccctcgcgctc
gtcgcgggcggcgaacggctcgaccacgccacgctcaacgcccgcgccaaccggctcgcc
caccacctcatcgcccgcggcgcgggacccgaacggctggtcgccctgcggctcccgcgc
accgccgacatgatcgtcgcgatcctcgccgtctggaagtccggcgccggttacctcccg
ctggacccggccctgccggaggaccgcatacggttcctcctcgacgacgcccgcccggcc
ctggtcctcgacgaaccggccctgcgcgccgtacccgaggacagcccggacaccgacccc
accgacgccgaacggcgcgcccccctcctggcggatcacaccgcgtacgtcatctacacc
tccggttccaccggccgccccaagggcgtcgccgtcacccaccgtgcggcggcgcacctg
ctggccgcccaccgggccgggttcgtcgccgaggcgggcggtggcccgctgcggaccgcg
ctcaccgcgtccttctccttcgacacctccctcgaaggcgtgctcctgatggccgacggc
cacccgctgcacctggtcgacgagaccacccgcatggacccggccgcactggtcgcgtac
gtcgtcgaacaccgcgtcgacttcctcgacgtcaccccgtcctacctgcggcagctgctg
cccgccggactgctcaccgatccccggcaccacccgcgggtcctcatgctcggcggcgag
gccgtcggccccgcgctctggcgcgaactggccgcccaccccgacgtggtcgcccacaac
ttctacggcccgaccgagtgcacggtcgacgcgctgtcctgccgcatcgacggcggggac
cgcccgctggtgggccgccccctgcccggggtgcgggcctatgtgctggacggccggctc
cgtccggtgccgcccggggtcggcggcgagctgtacctcgcgggcggccagctcgcccgg
ggctacacgggacggccggggctgaccgcggcccgcttcctgcccgacccgttcggcggg
cccggggagcggatgtaccgcaccggcgacctggcccgctggaccgccgacggccgcctg
gactacctcggacgcgccgacgaccaggtcaaggtgcgcggccaccgcatcgagcccggc
gagatcgaggccgccctcctcgcgctgcccgccgtctccgccgccgcggtcgtcgccctg
cccgacccgcacggccacgcccgtctcgccgcctacgtcgtccccgcgcccggcgcgccc
cggcccgtccccgccgacctgcggacggcgctgcgcgaggtgctgcccgacgcactggtc
ccttcctccttcacctgcctcgacgcgctgccgctgaccaccagcggcaaactggaccgc
cgcgccctgcccgcgccggaaagcaccccggaggaacgggagttcgtcgcaccgcgcacc
cccggcgaagaagctctggccggtatctgggccgaggtgctcgggacggcccgggtgggc
gtcaccgacaacttcttcgagctgggcggcgactcgatcctgagcatgcaggccgtctcc
cgtgcccgcgccgcaggcctgcgcatcaactcgcaggacgtcttccgccaccagacggtc
gccgacctggccgccgccgcgtcccgccgcaccgcctccgcacccgcgccccgccgcccg
cacgaggacgggcccgccccgctcacccccgtccaggagtggttcctcgccacacacggg
ccgctacggcacttcgccatgtcgatgctgctcgacctgccgtacgacctcgacgcacag
gccctcgaccgggccctgcacgccgtggtggcccgccacccggctctgcgcacccgcttc
acccgcaccgacgacacctggcggcagcaccccggcaccggcccggcgaccgggctgctc
acccgccacgactccgcaacggcacccgccgaggcggcggaagcggcccgcgcggccctt
gacccggcgaccggtgccctgctgcgcgcggccctgctgcccggcggggaacggccgcgg
ctgttcctcaccgcccaccacctggccgtcgacagcgtctcctggcgcgtactcctcgcc
gacctcgcacacgcctaccggcgggcggcggccggcgaggaccccctgccggaggccgag
cacaccccgttcgccgactgggcgcggaccctcgccgaacgggtccgggccggtgacctc
gacgacgacctggcccactggacgcgggaggcggcgcagccgcgcaccccgctccccgtc
gacctgcccggcgccccgctcgccggatcggtgcgcaccgtccgcacgcgcgtggaccgg
gacaccaccgaggcactgctgcggcgggtgccgagcgcgtaccggacccaggtcaacgac
gtgctgctgagcgccctcggccgggtgctcgccgactggacggacgccgaccgggtgacc
gtggccctggagggccacggccgcgaggaggaactcgacgagggcgccgacctgtcccgc
acggtcggctggttcaccacccagtacccggtcaccctgaccccggccggaggcgacgac
tggggcgccaccctcaagtccgtcaaggagcagctgcgcgccgtaccccgccggggcctc
ggctaccaggcgctcggccacctcggctcgccccggcccgaggcccgcgccctcggggaa
ctgccgctgcccgacgtgtgcttcacctaccacgggcagtgggaggcgtccgccggaggg
gacttcgcgcccgtcgccgacgtgcccggcagggacatggaccccgacgcgccgctggac
cacctcctcgacgtgtccgccctggtgaccgacggcgaactggagatcacctggcactac
agcgaccaggtgcaccgcgaggacaccgtccaggagctggcatcgggcctggcacgggcg
ctcaccgcgatcgccgagcactgcgcccgccccggcacgggcggacgcacaccctccgac
ttccccctggcccgcctggaccaggccggtgtggaccggctcgccggcgacggccgcgac
gtcgaggacctgctgccgctcaccccgctccaggaaggcatgctcttccaccggctggtc
ggcggggacgacgacgtgtacgtggaccaggccgcgctgctccttgagggcgtgagcgac
ccggacgcgctcgccctcgcctggcagcgggtgaccgaccgcacccccgccctgcgcacc
tcggtggtgtgggagggcgtcccggtgccgctccaggtcgtgcaccgccgcgtcgaggtg
cccgtcgtccagctggactggcgtgaactggacgcggcagagcgggccgagcgccttgag
cggctccgcgccgacgacctcgcccgcggcctcgacctcggcgccgcacccctgatgcgg
ctcaccctcgtccggctccccgacgcccggctgcacctgctgtggacctcccaccacctg
atcctggacggctggagcctcgcccaggtgctcaccgaggtgtccgacgagtacgcggcg
ctcaccaccggcgccgagccgcggccgccggcgcgccgcccgttcggcgactacgtgcgc
tggctcgccggccaggacaccggggcggcgcacgcgcactggcgtgccgtcctcgacggg
ttcaccacccccacgccgctgctcgtcgaccgcgcccggcgccccgggcacgagacccgg
tccgccgacgtgcacacggccgcgctgtccgacgaggtctccgcccgcctcgcccgcacc
gcgcggacggccggactcaccctcggcaccgtggtgcagggcgcctgggcgctgctcctg
tcgcgctacagcgccgaatcggacgtcctgttcgggaccaccgtctcgggacggcccgac
gacctgcccggcgccgatgcgatggtgggcatgttcatcaacacgctgcccacccgcgtc
cgcgtggacggcgaccgcacctccaccgactggctccgggaactccaggaggaacaggcg
caggcacggcggttctcggcggtgtccctcgccgagctgacctcgctgagcggcgtgccg
gccggcagccccctcttcgacagcatggtggccttcgagaactaccccttcgacgaggcg
cgttcggccacgaccggaatccgcctcaccgacgtctcctcccgggacgccaccaacttc
ccgctggtcctccgggcctaccagggggagcggttcggcttcgacctcgcctacgacccg
gagctgttcgacgccacgactgtacgcggcctcgccgaccggttctgcctgctgctcacg
gaactggccgacgaccccgaccggcccgtgcgcgccctcgcctggaccaccgccgaggag
cggcggcggatgctcaccgactggaacggcgccgcgtcgggccgccccgccgacacgctg
gacgcgctgttcgccgcccaggccgcccgcacccccgacgccgaggcgctcacctgcggt
gacgaacggctcgactacgccaccctggacacccgggcgagccgtctcgcccaccggctc
gccgaactcggcgccgggcccgagacgttcgtggccctcacgctgccccgctccgccgac
ctcgtcgtggccgtcctcgccgtgctcaagaccggcgccgcgtacctgcccgtcgacccc
cggctgcccgcggagcgcgtgcggcacatgctcgccgacgccggccccgtggcgctggtc
accacccgacaggacgagaccggcacggacgtaccgcgtctgctgctcgacgacccgcag
gtgcgtgccgacctggcccgccgcccggccgcggggccggccaggcgcgcgctgcccgag
agccccgcctacgccatctacacctccggctccaccggccgccccaagggcgtggtcgtc
ccgcacgccaacgtggtccgcctgttcacccgcacccggcactggttcgacttcgggacc
gacgacgtgtggacgctgttccactcctacgccttcgacttctcggtgtgggagctgtgg
ggaccgctgctgcacggcgggcggctcgtggtcgtccccgaggacaccgcgcgctccccg
gaggacttcctgcgcctgctcgccgacgagcgggtcaccgtcctcaaccagacgccgtcc
gcgttctacccgctcatccgggccgacgccgaactccccgacgccggcgaccgcctcgca
ctgcgcacggtgatcttcggcggcgaggcactggacgtcggcaggctcgccgactggtac
gcccgtcacccggacaccgcgccccgcctggtcaacatgtacggcatcaccgagaccacc
gtgcacgtcacccacgcccccctcgaccgcgcggcagcccgccccggcgccgcgagcccc
atcgggaccggcatccccgacctgcggctctacgtcctcgacggcacgctccaaccggtg
ccgccgggcgcggtgggcgaactgttcgtggccggggagggcctggcgcgcggctacctg
aaccggccggggctgacagcggcccgcttcctcgccgaccccttcggccggccgggcacc
cgcatgtaccgcaccggggaccgggcccgctggcgggccgacggcaccctggagtacctg
ggccgcgccgaccagcaggtcaagatccgcggctaccgcatcgagccgggcgagatcgag
gccgccctgcacggtcaccccggcgtcggcgcggccgccgtcggcgtgtacgaggacacc
gccgggacgcgacgcctcgtcgcccacgtcgtcggcaccggcacgggcgccggggagggc
ggggagtgcgccgcgccgccgtccgccgccgaactccgcgcgcacctcgaagggctgcta
cccgcgcacatggtgcccgccgcctatgtgccgctggacgcgctgccgctcaccgccaac
ggcaagctcgaccggcgcgccctgcccgcgccgggacccgacggcttcgccgccgacggc
acgcggaccccgccgcgcaccccggccgaacggctcgtcgccagcgcctggaccgacgtg
ctcgacaccggcgaagtcggagccgacgacgacttcttcgccctcggcggtgactccatc
ctcgccgtccgcgtcacctcccggctgcgcgccgccttcggcgcggaggtgtcgccccgg
ctgctgttcacccaccccgtgctccgcgacctcgcggccgccctgggcgaaccaggtggc
gcagacaccgccgacgccatcccggccaccgcccccggcgccccggcgcccctgtcgtac
gcccagcagcgcctgtggttcctcgaccagttcgagccgggcggcacggagttcaccacc
ctgtccgtgctgcggctgcgcggcccgctggaccaggacgccctgcgcgccgccctggac
ggcgtggtcgcccggcacgaggcgctgcgcaccacgttcaccgagcacgagggacaggcc
cggcagatcgtccacccgccacgccccgtcgacctgccggtgacggacctcgcggacgcc
accgccctggacgccctggtggacctggccgccgccacacccttcgacctggccaccggc
cccctgctgcgggcccggctcgcccggtcggcccccgacgagcacgtcctcgtcctggcc
gtgcaccacatcgtcaccgacggctggtccgtcggcgtactggcccgggacctgggcgag
ctgtacgcggccgccctggaggaccgccgcccggacctgcccgacctgcccgtccgctac
agcgactacgccgcctggcagcgctcgcgcgccgaccgcgcggagaccgaactcgcccac
tggcgccgggccctggacggcgtgagcccgctggagctgcccaccgaccggccccgcccg
gccgtccgcacccgcgacggcgccctggtgaccttcaccctgcccgccgcgctcaccgag
cggctgcgcgaacgggcacgggaggcggacgccaccctctacatgacgctggtgacggcc
tgccagaccctcctcgcccgctgggcgggccaggaggacgtcaccgtcggcaccgtcacc
gcgggccgtgaccgggccgaactgcacgacgtcgtcggtatgttcgtcaacacgctcgtg
ctgcgcgccagggtgcgtcccggcgttcccttcctgaacctgctcgccgaggtgcgcgac
accgtcctggcggcgttcgcccaccaggaggtgcccttcgaacgcgtggtggacgccctc
cagcccgagcgggacaccagccgcaccccgctgttccaggtcatggtcgccctgcacaac
ctcggcgccgagccgctccggctgcccggcctgacggcggagccggtgaccccgccggtg
cggaccgccacctacgacctcgccttcgacttcgtggagggcgacggaggactcaccggc
cacctggagtacaacaccggcctgttcgacaccggcaccgccgaacgcctcgccgcccgg
ctgcgcgtcctcctggaggccgtcgccgccgaccccgggcagagcgtggacacgctgccg
ctgatgaccgacgacgagcggcagcaggtgctgcgccacggagagggcgtccggctgccg
gagcccgacaccaccttccccgccctgttcgaggcccaggccgcccgcacccccgcgcac
accgcgctggccgcccgcgacaccaccctcgacttcgccgcgctgaaccagcgcgccaac
cggctcgcccaccacctcatcgcccggggcgcgggacccgaggacgtggtcgccgtccgg
ctgccccgcacctccgacctgatggcagccgtgctcgccgtcctcaaggcaggcgccacc
ctgctcttcctggaccccgaactccccgccgaacggcaggacgtcctcctcggcgacgcc
cgcccgcacaccgtgctgaccggcctcgacgcggtgccctgggacgggctgcccgcccac
gacccgaccgacgccgaccgtgtccggcccctgctgccgcggcaccccgcctacatcatc
tacacctccggctccaccggccgccccaagggcgtcgtcgtcgagcaccgcaacctggtc
aacctctgccacgatcaccgcgccggcctgctcgccccgcacaccgccggcggacagcgg
ctgcgcgccgcgctcagcgcctccttctccttcgacacctcctgggaaggccccctcctc
ctcgccctgggccacgaggtccacctgatcgacgaggacgtacgcctggacccgcgagcc
ttctgcgcccacgttgtcgaacaccggctcgactgggtcaacgtcaccccgacctacctg
cgcgaactcaccgccgccgatctcctggccgccgaccgccaccgcccgcgcctgctgctc
gtcggcggcgaggccctcaccccggccgactggcgcgacctcgtccgcgccgaacaggac
ctgggcgtggcggtgtacaacatgtacgggccgaccgagaccaccgtcgacgccgtctac
ggccgctgcgccggccagccgcaccgcccgctcatcggccgccccggcgccaacctgcgc
gcccacgtcctggacgccgccctgcgcccggtgcctccgggcacgcccggtgagctgtac
ctggccggggcgcaggtggcccgcggctacctgaaccggcccggcctgaccgcggcccgc
ttcacggcagacccgttcggggcgcccggcgagcggatgtaccgcaccggggaccgggtc
cgctgggaccgggacggacgcctggagttcctgggccgcaccgacgaacaggtcaagatc
cgcgggttccgcatcgagcccggcgagatcgaggccgctctcctcacccaccccgacatc
gccgacgccgcggtcgccgtccgcgagaacgccgggcgccccatgctcgtcggctatgtc
gtgcccgccaccggccgcgtcccgtccccggacgcgctgcgcctggcgctgcgccgcacg
ctgcccgaccacatggtgcccgcggcgttcgtcccgctggcccgcgtcccgcgcaccacc
agcggcaagacggaccgccgcgccctgcccgccccgcccgcacagcccgagagcggcaca
ccccacgtcgccccccgggccggcaccgaggagatcctggccgggatatgggcgcaggtg
ctgggtgtcgcacgcgtcggcgcccgtgacaacttcttcgcgctcggcggcgattccatc
ctgagcatccagatcgtctcccgtgcccgccaggccggcctcgtcctggccaccaaggac
gtcttccgccaccagacggtcgccgaactcgccctgcgggtacaggagtcggccccgccg
ccggacaccgaggaggaaccggccgaggcgccgctcaccccgatccagcactggtacctg
gagggccgcgcccccggacagcggctgcggttcaccatgacccagcgcctcgaactcgcc
ccggacaccgccgccgcgacgctgcggaccgccgtcgacgccctcgtgggccaccatgcc
gccctgcgcacccgattccgccgtaccgccgatggctggcgccaggacgtcctgcccgag
gcgccggacggcgtcttcacccggcatgacgtgtccggcctcgacgacacggcactggag
gacgaggtccagcggctgacgggcgaggcgcaggccgccctcgaccccaccgccgggcgg
gtgacgcgcgtgctgttcttcgaccgcggccccggccggccgggacaactggtcgtcacc
gcccaccacttggtcatcgacggtgtctcctggcgcatcctgctcgcggacctggagacc
gcgcaacgggcggcggcgctcggccgccccgtggaactgccccccacgggcacctcctac
ggccgctgggcggcccgcctggagcggcacgcccgctccggcgcgctcgacaccgacctg
ccgtactggacggacaccgccacggcgccggccgcgctgcccgcgggccggcccggtccg
aacacccacgccaccgccgccacccgcaccgtcaccctggacgcggagaccaccggggcc
ctgctgcgcgaggtcccgcgggcctaccgcacgcaggtcaacgacgtcctgctcagcgcc
ctcggccgcacccttgcccgctggtgcggacgtgacagcgtcctgctcggcgtcgagggc
cacggccgggaggagctgttcgccgacgtggacctgtcgcggaccgtcggctggttcacc
gccgagttcccactcgccctgcgcgtcgccccggacgccggctggcacgacaccctgcgc
gcggtcaaggaacaactgcgcgccgtgccgctgcacggcctgagccacggcgccctgcgc
catctcgtgcccggcagcccgctcgcctccggccccgccccgcaggtcggcttcaactac
cacggccagtgggacaccgacaccaccgatggcctgttccgccgcgccctgcccccggcc
ggcctcgacaccgacccggacgaaccccgcccctacctcctggacatcaccggcgtggtc
cagcggggccgcctcgaactcggcttcacctacccggccgccgtctacgaccaggcaacc
gtcgaccggctcgcccaggacaccctcacggccctgcgggagatcgtggcgcactgcgca
caccccgatgccggcggccgcaccccctccgacttccccctcgccggtctcggccaggag
cagctcgaccggctcctgggcaccggcagggacgccgaggacgtcctgccgctcaccccg
ctccagtccggcatgctcttccacggcctcgtggacaccgagcacgcctacttcgaccgc
acggccgtacggctgtccggcgtggccgacccgcaggtcttcgccgccgcctggcagcag
gtcgccgaccgcaccccggcgctgcgcaccagcgtccactggcagggcctgccccacccg
gtccaggtcgtccaccgccgcgcggaactgcccgtgcgccacctcgactggcgtgcgctc
gcgcccgccgagcgcgccgcggccaccgagcggctgctcgccgaggaccgcgccgcgggc
ctggacctggccaaggctccgctcacccggctgaccctggccgccctgcccggcgacgaa
gtgctcctggtgtggtccacccaccacatcgtcctcgacggctggagcaccgggcagctc
ctcaccgaggtgtgcgaacgctacgccgcgctcaccggcggccccgaccaggcgccgccg
gtgcggcggcccttcgccgacttcctgcactggctgcgggagcaggacgagacggcggcg
gaagggttctgggccgatgccctcgccgggttcaccgcccgcaccccgctgccgtacgac
agcaacccggccgaggcccaccgcgcccggtccacgcaggccgtccaccacgagctggac
gccgacgtctcccggcggctgcgagagacggccgcccgcgccggagtgaccgtgaacacg
gtggtggagggcgcctgggcgctgctcctcgcccgctccggcggacgcgacgacgtggtc
ttcggcaccaccgtctccggccgcccggccgaactgcccggcgtcgaaggcatgatcggc
atgttcatcaacacggtgccgacccgggcccgcgtacccgctgccgggccggtctcgacg
tggctgcgcgagctccaggaacgccagagcgaggcccgccgcttcgacttcctcgccctg
ccccgcatccaggccgtcagcgaggtgccgtccggacaggcgctgttcgacagcatggtg
gtcttcgagaactaccccgtggacgagtcggcgacggcccgcaccggagtgcgggtcgag
gaggtgcgcgccgacgacgccaccaccttcccctggtgcctccgcgcccacctcgccgaa
cacctcggctacgacctggcctacgaccccgagctgttcgacgccgccaccgccgagcgc
gccgcccaccgcctcgccgggctgctcaccgccctcgccgacgggttcgacaccgacctc
gccgagctggacgtgctcgccccggccgaccgcgcgctcctggccgcatggaacaccacc
gcccgcccggccgcgccgcgcagccccgtggacctgttcaccgagcagacgacgcgcacc
ccggacgcgatcgccgtcgacgacggcgagaaccggctgacctaccgggagctgcacgac
tgggcccgcgcactcgcggaccggctgcgggccgccggcctggcctccgaggaccgggtg
gcgctgcggctcgaccgttccgccgaactggtcgtcgcccagctcgcggtcctcatggcc
ggcggcgcctacgtccccgtcgacgcccgcgcccccgaggaacggcgccggaccctgctc
gcccaggcgggcgccaccctccggctcaccgccacggaggtgacagcggcccgcaccggg
accacggagacgtccgcacgccccgccgccgatcccgaccagctggcgtacgtgatgttc
acctccggatccaccggactgcccaaggcggtcgcggtgcggcaccgggacgtggcggcg
ctggccaccgacagccggttcaccggcggggtctgcgaccgcgtactgctgcactcgccg
gtcgcgttcgacgccgccaccttcgaggtgtgggccccgctcctgaacggcggccgcgtc
gtcgtggccccggacggcgacctcgacggggccgcgctgcgccggctcgccgccgacggc
ggactgaccgcgatgtggctgaccgccgggctcttccggctcctggcccaggacgcgccc
gactgcttccgcggcctcacgcaggtgtggaccggcggtgacgtcgtcccggcacaggcc
gtgcgccgggtcctcgacgcctgccccggcctgaccgtcgtggacggctacggcccgacc
gagaccaccaccttcgcgacctccttcgccctcaccgacccggcggcggtgcccgccacg
atccccgtcggacggccgctggacgacatgcgggcgctcatcctcgacacccggctgcgg
cccgtcccgccgggctgcccgggtgagctgtatctggccggcgagggcgtcgcccggggc
tacctgggccgcccgggcgagaccgccgcccgcttccccgccgacccgctcggtcctgcc
ggggcccgcatgtaccgcacgggcgacctggcgcggcggcgcccggacggcgccgtcgag
ttcctcggccgggccgacgaccaggtgaagatccgcggcttcagggtggagcccggcgaa
gtcgaggccgcgatcgccgcccacccggacgtcgtcgacgtggcggtcctggcccgcgag
gaccgccccggcgccagacggctcgtcgcctacgtcgtcggaccggccggccggaacggc
gaggcactgcgatcgttcgccgcccgcaccctgcccgactacctggtgcccacgaccgtc
gtcccgctcgccgcgctgcccctcagccgcaacggcaaggtcgaccgggccgcgctgccc
gtgccggaggccgcgccgggccgcgggcggaccgagccgcgcaccgaggcggagcgccgc
acggccgacgtcttcgccgaggtcctcgccggcgaaacacccggcgtggaggacgatttc
ttccagctcggcggcgactccatcctcagcatccggctggcctcccgcctggccgaggcc
ttcggcaccgacgtctcaccgcgcgccgtgttcacccactccacaccggccgccctggcc
cgcctcatcggcgagcggcgcggttccggccgtccggcactcgtcccccgcgcccgcgac
gcggtcgcgccgatgtcccatgcccagcagcgcctgtacttcctgcacgagttcgagccc
ggcggcgccgagtacgtcaccgccctcgccctgcggctgtgcggcaccctggacaccgac
gcgctgcgcgccgccctcggcgccgtggtggcccggcacgagtcgctgcgcaccaccttc
gacagcgtcgacggacacggcatccagcgcgtccacccgccccgcgacgtgccgctgccc
gtgcacgacctgtccgggctcggcgcgggggagcgggaaccggccgtgcgccgcctgctc
gccgaggaacgcctacgccccttcgacctgcgcgagggcccgctgctgcgcgccggactg
ctccggctcgccgacgacgagcacatcctcaccctcgccctgcaccacatcgtcaccgac
ggctggtccaccgccgtcctgctcggcgacctcgcacacttctaccgcgccgaacgcgga
gttccgcaggccgagctggcgccgctgccggtgcagtacgccgactacgcccactggcag
cgcaccaccggcgacaccgaggccgacgagcacctcgcctactggaaggaacacctggcc
gacacgccaccgctggagctgcccaccgaccggccccgccccccggtgcgcaccagcgcc
ggcgcgacgacccgcctggtggtgcccgccacgaccgccgggcggctcacccggctcgcc
cgggaccacggcaccaccttgttcaccgccctcgtggccgccgcccagagctacctcgcc
cggctctccggtggcggggacatagccgtcggcacggtcaacgccggccgcgaccggccc
gagacccaggccctcgtcgggttcttcgtcaacaccctggtgctgcgctcccgtgccgag
gccggtcaacccttcaccgagttcctcggtgacgtgcgaaggaccgtcctggacgccttc
gcccaccaggacgtgccgttcgaacgggtcgtggacgaggtgcagcccgtccgcgacacc
agccgcagcccgctcttccaggtcatggtcgtcctccagaacacccccaccgtcgacctc
gacctgcccggcctggacgtcaccgacgtcgaaccggaatcggagcaggccgcgttcgac
ctcaccctggagttcgccgagaccggctccggcgagctgcacgccctgctcacctacaac
accgacctgttcgaggcggccacggccgagcggatggcgggacagctcggcgcctggctg
cacgccatcgcggaggacccccgccgccccctcggcgccctgccgctgaccacggccggc
gagacggcgagcctgctcgaacagggccggggcgccttccgccccatacccgagtccacc
ctgcccgccctgttcgaacagcaggcggcccgcaccccggacgccgtggcactgatcgac
ggggaacgggaactgacctacgccgagacggaccgggccgccaaccggctggcccaccgg
ctcctgcgcgacggcgtcggacccgagcgcgtggtcgccctggcgctgccgcgctcggcg
gccgccgtggtggcgcagctcgccgtcgccaaggccggcggagccttcctgcccgtggac
cccgactaccctccgcagcgcagggagttcatgctcgcggacgccggcgccgagctgatc
ctcgacgacccggcccaggtatgggccgccgaagggccgacgaccgcgcccacggacgcc
gaccgcaccagcacgctcacccccgcccaccccgcctacgtcatctacacctccggctcc
accggcacgcccaagggcgtcgtcgtcacccaccggggcctggcctccttcgcggcggcg
gccgccgagcagtacgcggcgggccccggcgaccgggtcctgcagttcgcctccccgagc
ttcgacgcctccatcctggagctgtgcgtctccctgctcagcggagccacgctggtgacg
ggcgaggaagggccgctggtgggggagcggctggcggaggtactcgccgaacgccgcgtc
agccacacgctgatcccgccggccgcgctggccaccctgccggcgcggaccgccgccgac
ctgccccacctgcgcaccctcatcgtcggcgccgaggcatgcccggccgacctcgtcgac
acctgggccccgggacgcaggatggtcaactcctacggccccaccgaggccaccgtcgtc
gccacctggacaggaccgctgaccccgggcgccggagccccgcccatcggccgcccgtcc
ggcggcacccgcgtgtacgtgctcgacaccgccctgcgccccgtgccgcccggcgtgacc
ggcgagctgcacatcgcggggcccggcctggcccgcggctacctgggccggccgggcctc
accgcccagcgcttcctgcccgacccgttcggcgcacccggggagcggatgtaccgcacc
ggggacctggtccgctggagcgccgacggacaactgcggtacgcgggccgcgccgacgac
caggtcaaactgcgcggcttccggatcgaaccgggggagatcgagagcgcgctgcgacgc
agcccgctggtgcgggacgcggccgtggccgtccgggcaggagacgggcccggcaccccg
tcccggctcgtcgcctacgtcgtaccggagccgcccgccgccacgcacacccgccccgaa
ccgtccgggacaggctccccgggcaccgactcctccgcgaccgcgctgtccaccggggaa
ctgcgcctgcacctcgccgagacgctgccgccgcacatggtgccctcggtcttcgtgccc
ctcgaccggttgccgctctccccgaacggcaagatcgaccggcgtgcgctgcccgcaccc
ggcccggcccgggccatggacggcccgcagaccgcgccgcgcaccgacacggaacgccgc
atcgcccgcatctgggccgacgtgctgggcctcgcggaggtcggcgcggagggcaacttc
ttcgccctgggcggcgactccatcctgagcatgcaggtcgtctcccggatgcgccgcgac
gggctgcacgtggccacccgggacctgttcacgcaccagaccgtcgccgaactcgccacc
gtggtccgtaccgcgccccggcgctccgccgagggtccggtgaccggcgaggtaccgctc
accccgatccaggagtggttcctgaccacgccccgcgcggcccaccaccacttcaaccag
tcggccctgttcgaactcgacggccgccccgacccacgggcgctgcacaccgcgctcgac
gctctgatcgagcaccacgacgcgctgcgcatgcgcttcacccgcgacgaacacggctgg
cagcagtacaacccgccgcccgccgacggcgacgacgcccccgacatcctcgtacgacac
gacctgagcggtctgtcccccgaggacgccgacgcggcgatggcgaaggccgccgacgca
ctccacgtgagcttcgatctggcccgcggcccgcacctgcgggcggccctgttcaccggc
gaccccgaccggcccgcatacctcctcctcatcgcccaccatctggtggtggacgccgtc
tcctggcgcgtcctgcgcgatgacctggagaccgcctaccgccaggccctccagggtgaa
ccggtcgcgctgggcgagcgcggcaccagcttccgcgactggtcccggcggctggccgcg
cacgtcgccgagggcggcctcgaccacgaactgccgcactgggagcagacggtgggagcc
gagcccaccccggcggacccggcagcggcgaccggcgacggaccggccgccacggtgagc
gtggaactcgacgaggaggacaccacggccctgctgcgctccgcgcccaccgcctaccgc
acccgcgtcaacgacgtgctgctcaccgcgctcgccctggcactggcccgctggaccggc
cacgaccgcgtccgcctggacctggagggccacggccgcgaagacctgctcgacggcgtc
gacctctcgcgcaccgtcggctggttcaccaccgtccatccggtggccctgcacgttccg
gaccccggcggcctcggcccggaccgcgactggaggtccctggtgaagtcggtccgccgc
cagatgcgcgccgtgcccggcaacggcatcggctacggcgccctgcgcaccttcggcccg
cccgaggtccgcgaacgcctcggcgcccaggcccacagccaggtcgtgttcaactacctc
ggccagtgggacgcgcgccccgagacggcggacggcggcctggtccgcgccgaacacggt
tccttcggccaggaccacgatctgcgggaccccggttcccatccggtggaggtggtgggc
gcggtgcagcacggacgcctcgcctttacctggcaccaccggccgggcctgcacgacacg
gcggccgtacgccgggcggcggaggacttcgccgaggccctgcgcctcctcgcccgggac
gcccggggaggccggtga
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