Streptomyces sirii: WAB15_25445
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Entry
WAB15_25445 CDS
T11107
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
ssir Streptomyces sirii
Pathway
ssir00230
Purine metabolism
ssir00670
One carbon pool by folate
ssir01100
Metabolic pathways
ssir01110
Biosynthesis of secondary metabolites
Module
ssir_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ssir00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
WAB15_25445 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
WAB15_25445 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ssir04147
]
WAB15_25445 (purH)
Enzymes [BR:
ssir01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
WAB15_25445 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
WAB15_25445 (purH)
Exosome [BR:
ssir04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
WAB15_25445 (purH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
WXK79061
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Position
5640142..5641707
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AA seq
521 aa
AA seq
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MTATEGTQRPIRRALVSVYDKSGLEELAQGLHAAGVQLVSTGSTAAKIAAAGVPVTKVEE
LTGFPECLDGRVKTLHPKVHAGILADLRLEDHRRQLADLGVEPFDLVVVNLYPFKETVAS
GATADECVEQIDIGGPSMVRAAAKNHPSVAVVTDPAAYAAVLQAVKEGGFTLGLRKRFAA
AAFRHTAAYDVAVASWFAEDYAAADESGLPEFLGATYERKNVLRYGENPHQGAALYVNGE
GGLAEAEQLHGKEMSYNNYTDTDAARRAAYDHTEPCVAIIKHANPCGIAVGVDVAEAHRK
AHACDPLSAFGGVIAVNRPVSVAMAEQVAEIFTEVIVAPDYEDGAVEILARKKNIRVLRA
PGAPANPVEVKAVDGGALLQVTDRLQADGDDPANWTLATGEALSAGELAELAFAWKACRA
VKSNAILLAKDGASVGVGMGQVNRVDSAKLAVERAGEERARGSYAASDAFFPFPDGLEIL
TAAGVKAVVQPGGSVRDELVVEAARKAGVTMYFTGTRHFFH
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgccaccgaaggcacccagcggcccatccgccgcgcactggtcagcgtctatgac
aagtccgggctggaagagctggcgcagggcctgcacgcggcgggcgtccagctcgtctcc
accgggtcgacggccgcgaagatcgccgcggccggggtgccggtcaccaaggtcgaggag
ctgacgggcttccccgagtgcctcgacggccgggtcaagaccctgcacccgaaggtgcac
gcaggcatcctggccgatctgcgcctggaggaccaccgccggcagctggccgacctcggc
gtggagccgttcgacctggtcgtcgtgaacctttacccgttcaaggagaccgtcgcctcg
ggcgccactgccgacgagtgcgtcgagcagatcgacatcggcggtccgtcgatggtccgt
gccgccgccaagaaccacccctccgtcgcggtcgtcacggatccggccgcgtacgccgcg
gtcctccaggcggtcaaggagggcggcttcacgctggggctgcgcaagcggttcgccgcg
gcggcgttccggcacaccgccgcctacgacgtcgccgtggcctcctggttcgccgaggac
tacgcggccgccgacgagtcgggtctccccgagttcctcggcgccacctacgagcgcaag
aacgtgctgcgctacggcgagaacccgcaccagggcgccgcgctgtacgtcaacggcgag
ggcggcctcgccgaggcggagcagctgcacggcaaggagatgtcgtacaacaactacacg
gacacggacgccgcgcgccgtgccgcgtacgaccacaccgagccctgcgtcgccatcatc
aagcacgccaacccgtgcggtatcgcggtcggcgtcgatgtcgccgaggcgcaccgcaag
gcacacgcctgcgacccgctgtccgcgttcggcggggtgatcgcggtcaaccgcccggtg
tccgtggcgatggccgagcaggtcgcggagatcttcaccgaggtcatcgtggcgcccgac
tacgaggacggcgcggtcgagatcctcgcccgcaagaagaacatccgggtgctgcgcgcc
ccgggcgcgccggccaacccggtcgaggtcaaggccgtcgacggcggggcgctcctccag
gtcaccgaccggctgcaggccgacggcgacgacccggcgaactggacgctggccaccggc
gaggcgctgtccgccggcgaactggccgagctggccttcgcctggaaggcgtgccgcgcg
gtgaagtccaacgcgatcctgctcgccaaggacggcgcctcggtcggtgtcggcatgggc
caggtcaaccgcgtcgactccgcgaagctcgccgtcgagcgcgcgggcgaggagcgggcc
cgcggctcctacgccgcctcggacgcgttcttcccgttccccgacggcctggagatcctg
accgccgcgggcgtcaaggccgtggtgcagccgggcggttcggtccgtgacgagctggtc
gtcgaggccgcgcgcaaggccggcgtgacgatgtacttcaccgggacgcggcacttcttc
cactga
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