KEGG   Streptomyces sirii: WAB15_30730
Entry
WAB15_30730       CDS       T11107                                 
Name
(GenBank) amino acid adenylation domain-containing protein
  KO
K16416  myxalamid-type nonribosomal peptide synthetase MxaA
Organism
ssir  Streptomyces sirii
Brite
KEGG Orthology (KO) [BR:ssir00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    WAB15_30730
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:ssir01008]
    WAB15_30730
Polyketide biosynthesis proteins [BR:ssir01008]
 Polyketide synthase (PKS)
  PKS-NRPS hybrid
   Bacterial type (modular)
    Myxalamid hybrid PKS-NRPS
     WAB15_30730
SSDB
Motif
Pfam: Condensation AMP-binding NAD_binding_4 Epimerase PP-binding AMP-binding_C RmlD_sub_bind GDP_Man_Dehyd 3Beta_HSD
Other DBs
NCBI-ProteinID: WXK80020
LinkDB
Position
complement(6885733..6890133)
AA seq 1466 aa
MTPSPTRPLSFSQERVWFLEQLTPGTARQNIPLAVRLTGRLDVAALTEALRGVVRRHDVL
RSSVTVVDGVPVQRVEDPGPLAVPVADLRGGDRARTETAAGDWLRRQAQTPLPLDRAPLL
RAALARVGEDEHLLAVTVHHLAFDGWSVGVLMRELGDRYTAHTSGRDPELRELPLSYADF
AVRQRAAFDAGDMADDLAHWRDELAGELPVLELPTDRTRPETPAYRGATVSRVLSQGATE
ALTELVRAHGVTPYMVLLGGYAALLGRWSGRSSVVVGSPIAGRTDEDLEDLVGFFVNTMA
VRLDLTGDPGFDELLRQVRKKALGAYAHQGVPFEKIVEELAPDRESNRAPVFQTLFVLQN
APLEGLRLPGLTVQPLQVHNGTAGFDLQMSVSRLPQGLTVTLEYDTALFDEATAVRLLTQ
YETLLRGAAADPRTPVSRLPLLDADEAERLLALGRGGEDFPVSGSLHRSFEEQARRRPDA
TALTCGDRHLSYAELNAAADELALRLGELGIGGESLVGLYLDRGFDTVISILAVLKAGAA
YVPMDPAYPGPRVARILADARPPVLVVHERLRGRLPEFDGHLLVLDGTDRPAARPAPPAP
AARPGCPDNAAYVIYTSGSTGTPKGVQITHANVLRLFAATRSRYRFDHRDVWPLFHSYAF
DVSVWELWGALLHGGRLVIVPDETARDAEAYRELVRAEGVTVLNQTPSAFVHFSAADALR
DPAELALRLVVFAGEALEPGSLKGWFARHGDRTPRLVNMYGITETTVHVTLREMTLDDVT
MARRSPIGRPMPDLDMYVLDGQLQPVPTGTTGELYVGGPGLARCYFGAPALTADRFVPDP
FGRTPGARLYRSGDLARITPDGEIEYLGRSDHQIKVRGYRIEAGEIEAQLLDHPAVDSAV
VVPRPDPGGDMRLIAYVTGGEDPASGDELRALLEERLPGYMVPWRVVVLDALPLTVNGKV
DRAALPAPDSVRPAVATAYAEPRDDMERAVATAVAAVLRLDRVGRSDNFFELGGHSLLAT
RLVFRLRAELGTELPLRALFEVPTVEGIAAAVRTAKEHDGAAPAHTVRDLAADAVLPAGL
AGFDAPAPHLLAKPTHVLLTGATGFLGAFLLRELLRTTDAYVHCLVRAEDDAQARRRLAD
TARRYGLGDPGAESRVVPLAGDLAAPGLGLVPRELDRLADTVDAIYHCGADVNLVYPYEQ
LRAANVDGTAELVRLAGRTRRAPLHYVSTVGVFGAVPAHGGPVRETDPPGPADLLRQGYT
QSKWVGEQIVWRAAAAGLPVTVHRPSRIAGDSRSGACQTDDYLWRVVKGCVQAGAYPDDV
RVLTDLVPVDHVGAAIVALSHDPRALGRAHHLVNPRPVPLSEVLDHVRAFGYELAGLPFA
RWARTVAADPDNAAYPLLAVLESSAEAAGELRFAQDETAALLEPAALRCAAIDAELLHRH
LSHFVDTGFLPAPVRPHHNDTTRDHS
NT seq 4401 nt   +upstreamnt  +downstreamnt
atgacaccgtcacccacccgccccctctccttctcccaggagcgggtctggttcctcgaa
cagctcacccccggcaccgcgcggcagaacatcccgctggccgtgcggctgaccggccgg
ctggatgtggccgcgctgaccgaggcgctgcgcggcgtcgtgcgccgccatgacgtgctg
cgctcgtcggtcaccgtcgtggacggcgtcccggtccagcgcgtcgaggatcccggaccg
ctggccgtcccggtcgccgacctgcgcggcggtgaccgcgcgcggaccgagacggccgcc
ggggactggctgcgccggcaggcgcagacccccctccccctcgaccgggcgcccctgctg
cgggccgcgctggcgcgggtgggcgaggacgagcatctgctcgccgtgacggtgcatcac
ctagccttcgacggctggtcggtcggggtgctgatgcgggaactgggcgaccgctacacg
gcccacacctccgggcgcgaccccgaactgcgcgaactcccgctgagttacgcggatttc
gccgtccgccaacgcgcggcgttcgacgccggcgacatggccgacgacctggcgcactgg
cgggacgagctggccggcgagctgcccgtgctggagctgcccaccgaccgcacccgcccg
gagactcccgcctaccggggtgcgaccgtcagccgggtgctgtcccaaggcgccaccgag
gcgctgacggagctggtccgcgcccatggcgtgacgccgtacatggtgctgctcggcggg
tatgccgcgctgctcggccgctggagcggccggtcctccgtggtcgtcggcagccccatc
gccggccgtaccgacgaggacctggaggacctggtcgggttcttcgtcaacaccatggcg
gtgcgcctggacctgaccggcgatccgggcttcgacgaactgctgcgccaggtacgcaag
aaggcgctgggggcctacgcccaccagggcgtgcccttcgagaagatcgtcgaggagctc
gcccccgaccgggagagcaaccgcgcgcccgtcttccagaccctgttcgtcctgcagaac
gccccgctggaggggctgcggctgccgggactgacggtccagccgctccaggtgcacaac
ggcaccgccggtttcgacctgcagatgtcggtcagccggctgccccagggcctgaccgtg
acgctggagtacgacaccgcgctcttcgacgaggccacggccgtccggctgctgacgcag
tacgagacgctgctgcggggcgcggccgccgacccccgcacaccggtctcccggcttccg
ctcctcgacgccgacgaggccgagcggctgctggcgctgggccggggcggcgaggacttc
ccggtgagcggcagcctgcaccgcagcttcgaggagcaggcccgccgccgacccgacgcc
accgcgctcacctgcggagaccgtcacctcagctacgccgagctgaacgccgccgcggat
gaactcgccctgcgactgggcgagttgggcatcggcggcgagagcctggtcggcctctac
ctggaccgcggcttcgacaccgtcatcagcatcctcgccgtactcaaggccggagccgcc
tacgtccccatggacccggcctaccccggtccccgggtggcgcgcatcctcgccgacgcc
cgcccgcccgtcctcgtcgtccacgagcggctgcgcggacggctgccggagttcgacggg
cacctgctggtgctcgacggcaccgaccggcccgccgcccgccccgcaccgccggcgccg
gccgcgcgccccggctgcccggacaacgcggcgtacgtcatctacacctccgggtcgacc
ggcacgcccaagggcgtgcagatcacccacgccaacgtgctgcggctcttcgcggcgacc
cgctcccgctaccgcttcgaccaccgcgacgtgtggccgctgttccactcctacgccttc
gacgtgtccgtgtgggagctgtggggggcgctgctgcacggcgggcggctggtcatcgtg
ccggacgagacggcccgcgacgccgaggcctaccgcgagctggtgcgtgccgaaggcgtc
accgtcctcaaccagaccccgtcggcgttcgtgcacttctcggccgccgacgccctgcgc
gacccggcggaactcgccctgcggctggtcgtcttcgccggcgaggctctggagccgggc
agcctgaagggctggttcgcccgccacggcgaccgcaccccgcggctggtcaacatgtac
gggatcaccgagaccacggtgcacgtcaccctccgggagatgacgctggacgacgtcacc
atggcgcggcgcagccccatcggacgccccatgcccgacctggacatgtacgtcctggac
ggacagctccagccggtgcccaccggaaccaccggcgagctgtatgtgggcggcccgggt
ctggccaggtgctacttcggcgcgcccgccctgaccgccgaccggttcgtaccggacccg
ttcggccgcacccccggcgcacggctctaccgcagcggcgatctggcgcggatcaccccc
gacggcgagatcgagtacctgggccgctccgaccaccagatcaaggtccgcggctaccgc
atcgaagcgggcgagatcgaggcccagttgctcgaccaccccgcggtcgactccgcggtc
gtcgtgccccggccggacccgggcggcgatatgcggctgatcgcgtacgtcaccggcggc
gaggatccggcgtccggcgacgagctgcgggccctgctggaggagcggctccccgggtac
atggtgccctggcgggtggtggtcctcgacgcgctgcccctcaccgtcaacggcaaggtg
gaccgcgccgcgctgccggcccccgacagcgtccgcccggccgtggccaccgcgtacgcg
gagccgcgggacgacatggagcgggccgtggccacggccgtggccgcggtgctgcggctg
gaccgggtgggccggtcggacaacttcttcgagctgggcgggcactcgctgctggccacc
cggctggtcttccggctgcgtgccgagctgggcaccgaactgcccctgcgcgccctgttc
gaggtgcccacggtcgagggcatcgccgcggccgtccgcacggcgaaggagcacgacggc
gccgcgccggcgcacacggtccgcgacctggccgcggacgccgtactgcccgccggcctg
gccgggttcgacgcccccgcgccccatctgctcgccaagcccacccatgtgctgctcacc
ggcgccaccgggttcctcggcgcgttcctcctgcgcgaactgctgcgcaccacggacgcg
tacgtccactgcctggtgcgcgccgaggacgacgcgcaggcccggcggcggctggcggac
accgcccgccgctacggcctcggcgacccgggcgcggagagccgggtggtgccgctcgcc
ggtgacctcgcggcccccggcctgggcctcgtaccgcgggaactcgaccggctcgcggac
accgtggacgcgatctaccactgcggcgcggacgtcaacctcgtctacccgtacgagcag
ctcagggcggccaacgtggacggcaccgcggagctggtgcggctggccggccgcacccgg
cgcgccccgctgcactacgtctcgaccgtcggggtcttcggcgccgtgcccgcacacggc
gggccggtccgggagaccgatccccccggccccgccgacctgctgcgccagggctacacg
cagagcaagtgggtcggcgagcagatcgtgtggcgggccgccgcggccggactgccggtg
accgtgcaccggccgagccggatcgccggcgacagccgcagcggcgcctgccagaccgac
gactacctgtggcgggtggtcaagggctgcgtccaggcgggtgcctaccccgacgacgtg
cgggtgctcaccgatctggtgccggtcgaccacgtcggggccgccatcgtcgcgctgtcc
cacgaccccagggccctgggccgggcacaccacctggtcaacccgcggccggtgccgctg
agcgaggtgctggaccacgtccgcgccttcggctacgagctggccggtctccccttcgcg
cgatgggcgcgcaccgtcgccgcggacccggacaacgcggcctaccccctgctggccgtg
ctggagtcgagcgcagaggccgccggggaactgcgcttcgcgcaggacgagacggccgcg
ctgctcgaacccgccgcgctccggtgcgccgccatcgacgcggagctgctgcaccgccat
ctgagccacttcgtcgacaccgggttcctgccggccccggtacgcccccaccacaacgac
accacgagggaccactcatga

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