Saccharolobus solfataricus P2: SSO0977
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Entry
SSO0977 CDS
T00054
Symbol
leuA-2
Name
(GenBank) 2-isopropylmalate synthase (leuA-2)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sso
Saccharolobus solfataricus P2
Pathway
sso00290
Valine, leucine and isoleucine biosynthesis
sso00620
Pyruvate metabolism
sso01100
Metabolic pathways
sso01110
Biosynthesis of secondary metabolites
sso01210
2-Oxocarboxylic acid metabolism
sso01230
Biosynthesis of amino acids
Module
sso_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sso00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SSO0977 (leuA-2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SSO0977 (leuA-2)
Enzymes [BR:
sso01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SSO0977 (leuA-2)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
AsnC_trans_reg
Radical_SAM
AP_endonuc_2
ACT_4
SurA_N_2
NapD
Motif
Other DBs
NCBI-ProteinID:
AAK41252
UniProt:
Q97ZE0
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All DBs
Position
835585..836970
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AA seq
461 aa
AA seq
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MIKVGILDSTLREGEQTPGVIFTVDQRVEIAKALSDLGVSMIEAGHPAVSPDIYEGIKRI
VKLKKEGIITSEIVGHSRAVKRDIEIAAELEVDRIAIFYGVSDIHLKAKHKATREEALRV
IAETISYARSHGVKVRFTAEDGSRTDFDFLVTVSRTARDAGADRVSIADTVGILYPSKTK
ELFSALIREVPNLEYDIHAHNDLGLAVANALAAVEGGATIVHATVNGLGERVGIVPLQQI
VAAIKYHFGIEVVKLDKLQYVSSLIEKYSGIPMPPNYPITGDYAFLHKAGVHVAGVLSDP
RTYEFMPPETFGRTRDYTIDKYTGKHALRDKYEKLGVKISEAEMDQILAKIKSNTTIRFY
RDVDLLELAEEVTGRVLKPRPPEQIEALISVKCDSNVYTTSVTRRLSVINGVKEVMEISG
DYDILVKVQAKDSNELNQIIESIRATKGVRSTLTSLVLKKM
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgataaaagtaggtattttagattcgacgttaagagaaggagaacaaactcctggagta
atatttactgtagaccaaagagtagagatagctaaggctctatccgatttaggagtatct
atgatagaagccggtcatccggctgtatctccagatatttacgaagggataaaaagaata
gtcaaattgaaaaaagagggtattataacatcagaaattgtaggacacagtagagccgta
aaaagagatatagaaattgcagcagaattagaggtagataggatagcaatattttacggc
gtaagtgatatacatctaaaggcgaaacataaagcaacaagagaagaggctttaagggta
atagctgagacaattagttacgctaggagtcacggcgtaaaagtcagatttaccgcagaa
gatggttcaaggacagactttgacttcttagttacagtatcgagaacggctagagatgca
ggtgcggatagggttagtatagctgatactgtaggcatattatatccatcaaaaaccaag
gaattatttagcgcgttaataagggaagttccaaacttggagtatgatattcacgctcac
aatgacttaggtctagcagtagcaaatgcattggctgcagtagaaggtggagctacgatt
gttcatgcaacggttaatgggcttggagagagggttggtatagtacctttgcaacaaatc
gtagcagctattaagtatcattttggtatagaagtagttaaactagataaattacagtac
gtttccagtttaattgaaaagtacagtggaattccgatgccacctaattatcccataact
ggggattacgcttttttgcataaggcaggagttcatgttgcgggtgtgttgagtgatcct
agaacatatgaatttatgcctccagagacgtttggtagaacaagagattacactattgat
aaatatacaggaaagcatgcgttaagagataaatatgaaaaactaggtgtgaaaatcagt
gaggctgaaatggatcagattttagctaaaattaagtcaaatacgactataagattttac
agagatgtggatttactagagttagctgaagaagttaccggaagagttttgaagccaaga
ccacctgagcaaatagaagcgttaatttcagttaagtgtgattctaacgtttataccaca
tcagtaactcgtcgtttatcagttattaatggcgttaaagaggttatggaaatttcagga
gattatgacatactggtcaaggttcaagctaaggactctaatgaattaaaccagataatc
gaaagtataagagcaactaaaggtgtgagatcaacattaacatcattagtccttaagaaa
atgtaa
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