Streptococcus sobrinus: DK181_07215
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Entry
DK181_07215 CDS
T05567
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ssob
Streptococcus sobrinus
Pathway
ssob00300
Lysine biosynthesis
ssob00550
Peptidoglycan biosynthesis
ssob01100
Metabolic pathways
ssob01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ssob00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DK181_07215
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DK181_07215
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DK181_07215
Enzymes [BR:
ssob01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DK181_07215
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
AWN19234
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Position
complement(1490795..1492159)
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AA seq
454 aa
AA seq
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MKLSLHEIAGVVGAFNDISKFEDFPIHAIEFDSRKISSGDLFLPLKGTRDGHEFIPTAFE
NGAVATFSRIELDDVPYILVKDPLTAFQTLAKYYLEKMGVDVIAVTGSNGKTTTKDMIHD
VLATSYKTYKTQGNYNNEIGLPYTALHMPDDTQKIVLEMGQDHLGDIDLLSRIAQPKIGV
LTLIGEAHLEFFGSREKIAQGKMQIVNGMAKDGTLIAPADKIINTYLPENQKVVRFGPDQ
DIFLTELVERKDSLSFAVNFMDGLIELPVTGKYNATNAMLAAYVGQLEGVADEDIRSALK
HLELTKNRTEWKKASNGADILADVYNANPTAMKLILETFLTIPANEGGKKIALLADMKEL
GADSVQLHNNMIMAINPEDLDYLICYGEDIAGLAQLASQMFPLGKVYYFKKTDQEDQFED
MVKQVKQLLGPNDQILLKGSNSMHLDKVAQALEE
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaagcttacatgaaattgctggagtggtgggagccttcaatgatatttccaag
tttgaggatttccccattcatgctattgaatttgacagtcgcaagattagttctggcgac
ctctttttgcccctcaaggggacacgtgacggtcatgaatttatcccaactgcctttgaa
aatggggctgtggctaccttttctcgcattgagctggatgatgtgccctacatcctggtc
aaggatcccttgactgcctttcaaaccctggccaaatactatctggagaaaatgggtgta
gatgtgattgcagtgacgggctccaatggtaagactacgaccaaggatatgattcacgat
gtcttggccactagctataagacctacaagacccagggcaactataacaatgagattggc
ctgccttatacggccctccacatgccagatgatactcagaagattgtccttgagatgggg
caggaccaccttggtgatattgatcttctgtctaggattgcccaacccaagattggtgtc
ctgactctgattggcgaggcccatctagaatttttcggtagtcgtgaaaaaattgcccaa
ggtaagatgcagattgttaatggcatggctaaagatggcaccctgattgctccggcggat
aagattattaatacctatttgcctgaaaatcaaaaggtagtccgctttggccctgaccaa
gacattttcttgactgagctggttgagcgcaaggatagtttgagctttgcggtcaatttt
atggatggtttgattgagctccccgtgactggcaagtacaatgccaccaacgctatgttg
gcagcctatgttggccagcttgagggcgtggccgatgaggacattcgctcggccttgaag
catttagaattgaccaagaaccgcaccgagtggaagaaggccagcaatggtgccgatatt
ttggcagatgtttacaatgccaatccgacggctatgaagctgattttggaaaccttcctg
actattccagccaatgagggcggcaagaagattgccctcttggctgatatgaaggagttg
ggagcggattcggttcagctacacaataatatgattatggccattaatccagaggatttg
gactatctgatttgctacggggaggatattgctggtctggcgcaattagccagccagatg
ttccctctgggcaaggtctattattttaagaaaaccgatcaggaagatcagtttgaggat
atggtcaagcaggtcaagcaattgctagggcctaacgaccaaattttgctcaaggggtct
aattccatgcacttggataaggttgcccaagccctagaagaatag
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