KEGG   Solea solea (common sole): 131463848
Entry
131463848         CDS       T10853                                 
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
ssoe  Solea solea (common sole)
Pathway
ssoe00562  Inositol phosphate metabolism
ssoe01100  Metabolic pathways
ssoe04012  ErbB signaling pathway
ssoe04068  FoxO signaling pathway
ssoe04070  Phosphatidylinositol signaling system
ssoe04081  Hormone signaling
ssoe04140  Autophagy - animal
ssoe04150  mTOR signaling pathway
ssoe04210  Apoptosis
ssoe04218  Cellular senescence
ssoe04370  VEGF signaling pathway
ssoe04510  Focal adhesion
ssoe04620  Toll-like receptor signaling pathway
ssoe04625  C-type lectin receptor signaling pathway
ssoe04810  Regulation of actin cytoskeleton
ssoe04910  Insulin signaling pathway
ssoe04914  Progesterone-mediated oocyte maturation
ssoe05100  Bacterial invasion of epithelial cells
ssoe05132  Salmonella infection
ssoe05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:ssoe00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    131463848
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    131463848
   04370 VEGF signaling pathway
    131463848
   04068 FoxO signaling pathway
    131463848
   04070 Phosphatidylinositol signaling system
    131463848
   04150 mTOR signaling pathway
    131463848
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    131463848
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    131463848
  09143 Cell growth and death
   04210 Apoptosis
    131463848
   04218 Cellular senescence
    131463848
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    131463848
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    131463848
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    131463848
   04625 C-type lectin receptor signaling pathway
    131463848
  09152 Endocrine system
   04910 Insulin signaling pathway
    131463848
   04914 Progesterone-mediated oocyte maturation
    131463848
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    131463848
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    131463848
   05100 Bacterial invasion of epithelial cells
    131463848
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ssoe04131]
    131463848
Enzymes [BR:ssoe01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     131463848
Membrane trafficking [BR:ssoe04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    131463848
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B Ribosomal_S15 DUF2321 ABC1
Other DBs
NCBI-GeneID: 131463848
NCBI-ProteinID: XP_058491889
LinkDB
Position
1:complement(7908007..7921952)
AA seq 1068 aa
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDVVKDSEVQDFRRNILNVCKEAVDLRDNNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPSAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMTTIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRLVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLGRQVEAMEKLINLTELLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctcccaggccttcttcgggagaactatgggggatgcacttgatgccccccagcatc
ctagtggactgcctcttgccaaatggcatgattcttacattggagtgcctccgggaggcc
acgctgatcacagtcaagcatgagcttttcaaagaggccaggaagtaccctctataccat
ctgctgcaagaggagagctcctacatctttgtcagcgtcactcaggaggcagagcgggag
gaattttatgatgagacccggaggttgtgtgatcttagactcttccaagcctttctcaaa
gttattgagccagtgggcaacagagaagagaaaattctcaaccgtgagataggttttgct
attggaatgcctatatgtgagtttgatgtggtgaaagattcagaagttcaggacttcagg
aggaacattttaaatgtttgcaaagaagctgtggacctccgagacaacaacggaccacac
agtagagctttgtacgtgtaccctccaaatgtagaatcctcagtagaacttccccgacac
atctacaacaaactagataaaggtcaaatcatagtcgtcatttgggttattgtgtcaccc
agcaatgacaaacagaagtataccctaaaaatcaaccatgactatgtgccagagcaggta
atagcagaagccattcgtaagaagacacgcagcatgctgctctctcaggagcagttgaag
atgtgtgtgcaggagtatcagggaaaatacatcctcaaagtctgtggctgtgatgagtac
ttactggagaaataccctctgagtcagtacaagtatgtgcgcagctgtatcatgctggga
cggatgcccaacctgatgctaatgtcaaaagacagcttgtactctcagttacccatggac
aatttcaccatgccatcatatgcaaggcgaatatctacagcgacaccttacatgaatggg
gaaacagccaccaagtctctgtggactataaacggaacactaaggatcaggatattgtgc
gccacatacgtcaatgtcaatatcagagacattgacaagatctacgtcaggaccgggata
taccacggtggagagcagttatgtgacaatgtcaacactcagcgggtgccctgttcaaac
cctaggtggaatgagtggcttaactacgacatgtacattccagacatccccagtgctgca
agactctgcctctccatctgctctgtgaaggggaggaagggtgctaaagaggagcactgt
cctctggcctggggcaatatcaacttgtttgactatacccacacattagtagcaggaaag
atggctctcaacctttggcctgtcccacacggtttggaggacctgttaaaccctatcggc
gtcacaggttccaaccccaacaaggaaaccccttgtcttgaactggagtttgaccatttc
agttgccctgtcaagttcccagatatgaccaccattgaggatcatgcaaactggaatata
tccagagagttaggtttcaattactgccacactggtttgagtaacagactggcacgtgac
aaccccctgactgacagcgataatgagcagctacgactggtatgcaacagagacccgctg
tctgaaatcactgagcaggagaaagactttctgtggaggcacagacaagactgtgtcaac
atgccagagatccttccaaagatcctgttggctgtgaaatggaactccagagatgaggtt
gcacagatgtattgccttctgaaggactggcctgctatcaagccagaacaagccatggag
ttgctggattgcaacttccccgatcccatgatcagagagtttgccgtgaagtgccttgag
aaatatctaacggatgacaaactttctcaatatctcattcaactagttcaggttctaaag
tatgagcagtaccttgataacccacttgcacgcttcttgctgaaaaaggcattaaccaat
caaaggataggacatttcttcttctggcatttaaagtcagagatgcacaacaagacggtg
agccagcggtttggcctgctgctggaatcgtactgccgggcctgtggcatgtatctgaag
cacctgggcagacaggtggaggccatggagaaacttatcaatctcactgaactcctcaaa
caggagaaaaaagatgaggcacagaaggttcaaatgaagtttctggtggagcagatgaga
agacctgactacatggatgcactacaaagcttcacctccccactgaatcctgctcatcag
ctgggaaacctgcgcctggaggaatgcaggatgatgtcatcagccaagcgacctctatgg
cttaattgggaaaacccagatatgatgtcagagttgctctttcagaacaatgaaatcatc
ttcaaaaatggagatgatctgaggcaggacatgctgacactgcagatcattaggataatg
gagaacatctggcagaaccaaggccttgatctcaggatgctgccgtacggttgcctctca
atcggcgactgcgtcgggttgatcgaggtggtgaggaactctcacaccatcatgcagatc
cagtgtaaaggaggcctgaagggggcactgcagttcaacagccacacactgcatcagtgg
cttaaagataagaacaagggagagatgtatgaccaggccatagatctgttcacacgttca
tgtgcaggctactgtgtagccacatttatcctgggaataggagacagacacaatagcaac
attatggtcaaagatgatggacagctgttccacatagacttcggccatttccttgaccac
aaaaagaagaaatttgggtataagagggaacgggtgccctttgtgcttactcaggacttc
ttgatcgtcatcagcaaaggaactcaagagtgcaccaaaacaagggagttcgaaaggttc
caggaaatgtgttacaaagcgtacctggcgatccggcagcatgccaacctcttcattaat
ctcttctccatgatgctgggctccggcatgccagagttgcagtcatttgacgacattgct
tacatcaggaagaccctggccctggacaagaccgagcaagaggcccttgactacttcatg
aagcagatgaacgatgctcaccatggtggctggactactaaaatggactggatctttcac
acaatccgccagcacgccatgaactaa

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