Solea solea (common sole): 131469900
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Entry
131469900 CDS
T10853
Symbol
hsd17b2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
ssoe Solea solea (common sole)
Pathway
ssoe00140
Steroid hormone biosynthesis
ssoe01100
Metabolic pathways
Module
ssoe_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ssoe00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
131469900 (hsd17b2)
Enzymes [BR:
ssoe01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
131469900 (hsd17b2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
131469900 (hsd17b2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF4235
Motif
Other DBs
NCBI-GeneID:
131469900
NCBI-ProteinID:
XP_058501301
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Position
12:complement(2165548..2168606)
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AA seq
396 aa
AA seq
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MTLLRVELSSEQMTMTMTMMFSCGVAAAAVCVFTVVWTRAEGCDDGRGGGASGVLWTTVL
LAAALCYIVSPAVSGVVVLCCVLMKICVRKRRRDLRTRGAVLITGCDSGFGHTLALELSH
MGVTVFAGVLDVKGGGAQRLRARASEKLQVLQLDVTDSVQVETVRQYVCAQVGRTGLWGL
VNNAGILPCPADAELLPLSDYRRCMDVNFLSAVHMCQVFLPMLRRSRGRIVNVSSLAAEV
PMPLFAAYGASKAALGAFSAMMRLETSQWNVNVSLIQPSGFRTNLFGDSDVISHYKDHLL
ASASSEAREDYGDSYISSLPSCLSSMSQTSAEDLSPVVDAMCHALLSVHPRAVYSPGQMG
WLLPFLHRHCPTAIFDLIITTLITYRDSEPAGLRTT
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
atgacattactgagagtggagctgagctcagagcagatgacaatgacgatgacaatgatg
ttcagctgcggcgtcgcagctgccgccgtctgcgtcttcacggtcgtgtggacgcgagca
gagggttgcgatgatggacgtgggggcggggccagtggcgtcctgtggacgaccgtcctg
ttggccgccgccctttgttacattgtctctcctgctgtgagcggagtcgtcgtcctctgc
tgcgtcctgatgaagatctgtgtgaggaagaggagacgagacctaaggacgaggggggcg
gtgcttatcacagggtgtgactctggctttggccacacccttgcgctggagctgagtcac
atgggggtgacggtgttcgcaggagtgttggacgtgaaagggggcggagctcagcgtctg
agagctcgagcgtctgagaagctgcaggtgctgcagctcgacgtgacggacagcgtccag
gtggagacagtgcgtcaatacgtctgcgctcaggtgggacgcacaggtctctggggtttg
gtgaacaacgcaggaatccttccatgtcccgcagatgccgagctcctcccactctctgac
tacagacgctgcatggacgtcaacttcctgtcagctgtccacatgtgtcaggtcttcctc
cctatgctgagacgctcacgaggacgcatcgtcaacgtgtccagcctggcagcggaggtt
ccgatgccactgttcgctgcgtacggagcgtctaaagctgcactcggcgctttctccgcc
atgatgagactggaaacttctcagtggaacgtgaacgtgtcactgatccaaccatcaggg
ttcagaaccaatctgtttggggacagtgatgtcattagtcattacaaagaccacctcctg
gcgtcggcgtcctctgaagccagagaggattatggggactcgtacatctcgtccctcccc
tcctgtctgtcctccatgtcccagacttcggcagaggatctgtcccctgtggtggatgcc
atgtgtcacgctctgctgtccgtccatcccagagccgtgtactcacctggacagatgggc
tggcttctgccgttccttcaccgccactgtcccaccgccatctttgacctcatcatcacc
acgctcattacatacagagacagtgagcctgcaggactgaggaccacctga
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