Streptomyces malaysiensis HNM0141: I1A49_13250
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Entry
I1A49_13250 CDS
T07406
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ssoi
Streptomyces malaysiensis HNM0141
Pathway
ssoi00300
Lysine biosynthesis
ssoi00550
Peptidoglycan biosynthesis
ssoi01100
Metabolic pathways
ssoi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ssoi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
I1A49_13250
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
I1A49_13250
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
I1A49_13250
Enzymes [BR:
ssoi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
I1A49_13250
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
Motif
Other DBs
NCBI-ProteinID:
QPI55762
LinkDB
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Position
complement(3388945..3390384)
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AA seq
479 aa
AA seq
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MIALSLTEIAGLVGGQPHDIPDPDLKVTGPVVIDSREVRPGSLFAALPGERVDGHDFARG
AVEAGATAVLAARPVGTPDAPVPAIVVPDVIAAMGVLARAVVERLGATVVALTGSAGKTS
TKDLIAQLLQRRGPTVWTPGSLNNEIGLPLTAMSADEATQHLVLEMGARGKGHIRYLTDL
TPPRIGLVLNVGTAHIGEFGGREQIAEAKGELVEALPTAEEGGVAVLNADDPFVRAMASR
TKARTVLFGEAEDADVRAGNVRLADGGRPAFTLHTPTGCSEVTMRLYGEHHVSNALAAAA
VAHELGMSVDEIAVALSEAGQLSRWRMEVTERSDGVTVVNDAYNANPESMRAALRALVAM
GAVTPGRRTWAVLGPMAELGEESLAEHDAVGRLAVRLNVSKLVAVGGQEAAWLDMGAKNE
GSWGEESVHVSDVRAAVDLLRSELRPGDVVLVKASRSVGLERLAQALLDGEGEVAGPWA
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgcactgtccctcaccgagatcgccggcctagtcggtggacagccgcacgacata
ccggacccggacctgaaggtcacgggccccgtcgtgatcgactcccgtgaggtgcgaccg
ggcagcctcttcgccgcgctccccggggagcgcgtggacggccacgacttcgcacgaggt
gcggtcgaggcgggcgccacggccgtcctggccgcccgccccgtcggcacgccggacgcc
cccgtaccggcgatcgtcgtgcccgatgtgatcgccgccatgggagtgctcgcgcgcgcc
gtcgtggagcgcctgggcgccaccgtggtggcgctcaccggctccgcgggcaagaccagc
accaaggacctcatcgcccagctgctccagcgccgcggacccaccgtatggacgccgggc
tcgctcaacaacgagatcggcctgccgctcaccgcgatgagcgccgacgaggccacccag
cacctggtgctggagatgggcgcccgcggcaagggccacatccggtatctgacggacctc
accccgccgcgtatcggactcgtgctcaatgtcggcaccgcccatatcggcgagttcggc
ggccgcgagcagatcgccgaggccaagggtgagctcgtggaggccctgcccacggccgag
gagggaggggtggcggtgctcaacgccgacgaccccttcgtgcgcgccatggcgtcgcgt
accaaggcccgtaccgtcctgttcggcgaggccgaggacgccgatgtgcgtgccgggaat
gtccggctcgccgacggcggccgccccgccttcacgcttcacacccctaccgggtgcagc
gaagtgaccatgcgcctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgcc
gtcgcccatgagttgggcatgtccgtcgacgagatcgccgtggcgctctccgaggcgggt
cagctctcccgctggcggatggaggtcaccgagcgctcggacggcgtgacggtcgtcaac
gacgcctacaacgcgaaccccgagtccatgcgagccgcgctgcgcgcgctggtcgccatg
ggcgctgtcacaccggggcgtcgtacgtgggcggtgctcggcccgatggccgagctgggc
gaggagtcactggccgagcacgacgcggtcgggcggctggccgtccggctcaacgtcagc
aagctcgtggcggtcggcggccaggaggccgcctggctggacatgggcgccaagaacgag
ggttcgtggggtgaggagtcggtgcacgtgtccgacgtgcgggcagcggtcgatctgctg
cgcagcgagctgcgaccgggggacgtcgtgttggtgaaggcatccaggtcggtcggcctg
gagcggcttgcgcaggcattgctcgacggtgagggtgaggtcgccggcccatgggcatga
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