Streptomyces malaysiensis HNM0141: I1A49_21970
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Entry
I1A49_21970 CDS
T07406
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ssoi
Streptomyces malaysiensis HNM0141
Pathway
ssoi00290
Valine, leucine and isoleucine biosynthesis
ssoi00660
C5-Branched dibasic acid metabolism
ssoi01100
Metabolic pathways
ssoi01110
Biosynthesis of secondary metabolites
ssoi01210
2-Oxocarboxylic acid metabolism
ssoi01230
Biosynthesis of amino acids
Module
ssoi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ssoi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
I1A49_21970
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
I1A49_21970
Enzymes [BR:
ssoi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
I1A49_21970
4.2.1.35 (R)-2-methylmalate dehydratase
I1A49_21970
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QPI57225
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Position
5486930..5488180
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AA seq
416 aa
AA seq
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MNLVEKILARASGKPSVEPGEIVIAEVDMLLMHDLSGYLTSGVYDKQVGLPIPHPERTLM
VFDHHYSPPTEQQADVLHHNREWARRTGINLLDCGNGNLHHAAVRGGFVKPGMIVVGSDS
HTPVHGALGALAVALGNDSHAGTVLPYGKAWFRVPETVRIELTGEPRPGTTPRDIALWLT
AEIGEGTMNYKALEFTGPYVKQLGFWDRWLFPLLCVDLGAKSSYVEPDEVTEAFVRTLPG
GLPYDLPRGDGGEAATVLRYDVSDVVPQVACPPTVGNAKAVSDVAGRQVRYAELGGHGGG
RIEDIRTAAEVLHGHTVHPDTRFNIVPSSREVFAQAVREGLVLALHEAGATWFPPSTGSN
QAINMGAMAAGEAMISTHARNFPGRNGSTRAEMYLASARTVAASAVAGEIAERSTR
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
gtgaacctggtcgagaagatcctcgcgcgggcgagcggcaaaccgtccgtggagcccggc
gagatcgtcatcgccgaggtggacatgctgctgatgcacgacctcagcggctatctcacc
tccggcgtctacgacaagcaggtcggtctgccgatcccgcatcccgagcgcaccctgatg
gtcttcgaccaccactactcgccgcccaccgagcagcaggccgatgtgctccaccacaac
cgcgagtgggcccgccgcaccggtatcaacctcctggactgcggcaacggcaacctccac
cacgccgcggtgcgcggcggcttcgtcaagcccggcatgatcgtcgtcggctccgacagc
cacacgcccgtgcacggcgcgctcggcgccctcgccgtggcgctcggcaacgactcgcac
gccggcacggtcctcccgtacggcaaggcgtggttccgggtgcccgagaccgtgcggatc
gagctgacgggggagccacggcccggcacgacgccccgggacatcgccctgtggctgacc
gcggagatcggcgagggcacgatgaactacaaggcgctggagttcaccgggccctacgtc
aagcagctgggcttctgggaccgctggctgttcccgctgctctgcgtggacctgggcgcc
aagagcagctacgtggagcccgacgaggtcaccgaggcgttcgtgcgcaccctgccgggc
ggtctgccgtacgacctgccgcgcggtgacggcggcgaggccgcgaccgtgctgcggtac
gacgtgagcgatgtggtgccccaggtcgcctgcccgccgacggtcggcaacgccaaggcc
gtctcggacgtggccggccgccaggtgcggtacgcggagctcggcggccacggcggcggc
cggatcgaggacatcaggacggccgctgaggtgctgcacggccacaccgtccacccggac
acccgtttcaacatcgtgccgtcgagccgcgaggtgttcgcgcaggccgtgcgggagggt
ctggtgctcgcgctgcacgaggccggagccacgtggttcccgccgagcaccggctccaac
caggccatcaacatgggcgcgatggcggcgggcgaggccatgatctccacccatgcccgc
aacttccccgggcgcaacggcagcacccgggccgagatgtacctggcgtccgcgcggacc
gtggcggcgtcggccgtggcgggcgagatcgccgagaggagcacccggtga
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