Streptomyces spectabilis: CP982_15770
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Entry
CP982_15770 CDS
T07323
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sspb
Streptomyces spectabilis
Pathway
sspb00790
Folate biosynthesis
sspb01100
Metabolic pathways
sspb01240
Biosynthesis of cofactors
Module
sspb_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
sspb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CP982_15770
Enzymes [BR:
sspb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CP982_15770
6.3.2.17 tetrahydrofolate synthase
CP982_15770
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QEV64686
UniProt:
A0A5P2XQ92
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All DBs
Position
complement(3638298..3639833)
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AA seq
511 aa
AA seq
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MSDLPPNDSPRDDESGPAGSADQFDDIVAAETDRDPDLAVIEAGSRTLRTQAGPPEADVP
SRPADPEVDRALREVEGELAARWPETKLDPSLRRIAALMDVLGEPQRAYPSIHITGTNGK
TSTARMIEALLGAFELRTGRYTSPHVQSITERISLDGAPIAPERFIEAYQDIKPYVELVD
AKEEHRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDGAVAVVTPIDLDHT
DRLGTTPAEIAVEKSGIVKQDATVILAQQPVEAAQVLLKKAVEVDATVAREGLEFGLVGR
QVAVGGQLLSLRGLGGEYEEVFLPLHGEHQAHNAAVALAAVEAFFGVGAQRVEPLDIETV
RKAFATVSSPGRLEVVRRSPTVVLDAAHNPAGARAAAASISEVFDFSRLIGVLGVSDGKN
ARGMLEAFEPLFAEVVVTQNSSDRALGADELAAIAVEIFGDDRVQVEPRLDDALEAAVTL
AEEEGEFAGGGVLVTGSVITVGEARLLLGRR
NT seq
1536 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgacctccctccgaacgacagcccgcgcgacgacgagtccggcccggccggctcg
gccgaccagttcgacgacatcgtcgcggccgagaccgaccgtgaccccgacctcgccgtg
atcgaggcgggcagccgcaccctgcgcacccaggcgggcccgcccgaggccgacgtcccg
tcccgccccgccgaccccgaggtggacagggcgctgcgcgaggtcgagggggagctcgcg
gcccgctggcccgagaccaagctggacccgtccctgcggcgcatcgccgcgctgatggac
gtcctcggcgagccccagcgcgcgtacccctcgatccacatcacggggacgaacggcaag
acgtccacggcccgcatgatcgaggccctcctcggcgccttcgagctgcgcaccggccgg
tacacatcgccgcacgtccagtcgatcaccgagcgcatcagcctggacggcgcccccatc
gcccccgagcgcttcatcgaggcgtatcaggacatcaagccgtacgtggagctggtcgac
gccaaggaggagcaccgcctctccttcttcgaggtgctcacgggcatggcgtacgcggcc
ttcgcggacgccccggtcgacgtcgccgtcgtcgaggtcggcatgggcggcacctgggac
gccacgaacgtgatcgacggcgcggtcgccgtcgtcacccccatcgacctggaccacacc
gaccggctcggcaccacgcccgccgagatcgccgtggagaagtccgggatcgtcaagcag
gacgcgacggtcatcctggcccagcagccggtggaggccgcgcaggtgctcctgaagaag
gccgtcgaggtggacgccacggtcgcgcgcgagggcctggagttcggcctggtcggccgt
caggtcgccgtcggcggacagctcctctcgctgcgcggcctcggcggggagtacgaggag
gtgttcctgccgctgcacggcgagcaccaggcgcacaacgccgcggtggcgctcgccgcc
gtcgaggcgttcttcggcgtcggcgcccagcgcgtggagcccctggacatcgagacggtc
cgcaaggccttcgccacggtgtcctccccgggccgccttgaggtggtccgccgctcgccc
acggtcgtcctggacgccgcgcacaacccggcgggtgcgcgtgccgccgccgcctccatc
agcgaggtcttcgacttcagccgcctgatcggcgtcctcggcgtgagcgacgggaagaac
gcgcgcggcatgctggaggccttcgagcccctcttcgcagaggtcgtcgtcacgcagaac
tccagcgaccgcgcgctcggcgccgacgagctcgcggccatcgccgtcgagatcttcggc
gacgaccgcgtccaggtcgagccccgtctggacgacgccctggaggcggcggtcacgctc
gccgaggaggagggcgagttcgcgggcggcggcgtcctcgtcaccggctccgtcatcacc
gtgggtgaggcccgactgctcctggggaggcgctga
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