Streptomyces spinosirectus: LXH13_20330
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Entry
LXH13_20330 CDS
T08958
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sspn
Streptomyces spinosirectus
Pathway
sspn00280
Valine, leucine and isoleucine degradation
sspn00640
Propanoate metabolism
sspn00785
Lipoic acid metabolism
sspn01100
Metabolic pathways
sspn01110
Biosynthesis of secondary metabolites
sspn01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sspn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LXH13_20330 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LXH13_20330 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LXH13_20330 (pdhA)
Enzymes [BR:
sspn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LXH13_20330 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
UIR19252
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All DBs
Position
complement(4395644..4396780)
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AA seq
378 aa
AA seq
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MTVMEQRGAYRPSPPPAWQPRTDPAPLLPDAEPHRVLGTEAAAKADPALLRRLYAELVRG
RRFNTQATALTKQGRLAVYPSSTGQEAGEVAAALALREQDWLFPSYRDTLAAVARGLDPV
QALTLLRGDWHTGYDPREHRVAPLSTPLATQLPHAVGLAHAARLKGDDVVALAMVGDGGT
SEGDFHEALNFAAVWQAPVVFFVQNNGFAISVPLAKQTAAPSLAHKAVGYGMPGRLVDGN
DAAAVHEVVSAAVSRAREGGGPTLIEAITYRIDAHTNADDATRYRGDSEVEAWRAHDPIA
LLEHELTERGLLDEDGMKAARDAAEAMAADLREHMNQDPVLDPMDLFAHVYAEPTPQLRE
QQAQLQAELHAEQEGGHR
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgacggtcatggagcagcggggggcctaccggccatccccgccgcccgcctggcagccc
cgcacggaccccgcgccgctgctgcccgacgccgagccccaccgcgtcctcggcaccgag
gcggccgcgaaggccgacccggccctgctgcgccggctgtacgcggaactggtccgcggc
cgcaggttcaacacgcaggcgaccgccctcaccaagcagggccgcctggccgtctacccc
tccagcaccggccaggaggccggcgaggtcgccgccgcgctggccctgcgggagcaggac
tggctcttccccagctaccgggacacgctggccgccgtcgcccgcggcctggaccccgtc
caggcactgactctgctgcgcggcgactggcacaccggctacgacccgcgcgagcaccgc
gtggcgcccctgagcaccccgctcgccacccagctcccgcacgccgtgggcctcgcgcac
gccgctcgcctcaagggcgacgacgtggtcgcgctcgccatggtcggcgacggcggcacc
agcgagggcgacttccacgaggcgctgaacttcgccgccgtctggcaggccccggtcgtc
ttcttcgtccagaacaacggcttcgccatctccgtcccgcttgccaagcagactgcggcg
ccgtcgctggcccacaaggccgtcggctacggcatgccgggacgcctggtcgacggcaac
gacgcggccgccgtgcacgaggtggtcagcgccgccgtgagccgcgcgcgggagggcggc
ggtcccacgctgatcgaggcgatcacgtaccgcatcgacgcccacaccaacgccgacgac
gcgacgcgttaccgcggcgacagcgaggtcgaggcctggcgggcgcacgacccgatcgcc
ctcctggagcacgagctgaccgagcgcggcctgctcgacgaggacggcatgaaggcggcc
cgcgacgccgccgaggcgatggccgccgacctgcgcgagcacatgaaccaggacccggtg
ctcgaccccatggacctcttcgcgcacgtctacgcggagcccaccccgcaactgcgcgaa
cagcaggcccagttgcaggccgagctgcacgccgagcaggaaggcgggcaccgatga
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