Streptomyces spinosirectus: LXH13_28180
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Entry
LXH13_28180 CDS
T08958
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sspn
Streptomyces spinosirectus
Pathway
sspn00290
Valine, leucine and isoleucine biosynthesis
sspn00660
C5-Branched dibasic acid metabolism
sspn01100
Metabolic pathways
sspn01110
Biosynthesis of secondary metabolites
sspn01210
2-Oxocarboxylic acid metabolism
sspn01230
Biosynthesis of amino acids
Module
sspn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sspn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
LXH13_28180 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LXH13_28180 (leuC)
Enzymes [BR:
sspn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
LXH13_28180 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
LXH13_28180 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
UIR20677
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Position
6083117..6084547
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRLSGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPDGVTA
KDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRPHAPEGADWDAAVEYWKTLRTDDDAEFDAEVVIDASELAPFVTWGTNPGQGAPL
SSSVPDPASYEDASERLAAEKALEYMGLEAGQPLRAIKVDTVFVGSCTNGRIEDLRAAAE
IVKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVTGHLASPADLTDATAAAPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctccacctcctgcacgaggtgaccagtccgcaggcc
ttcgacggcctgcgtctcagcggccgcccggtgcgccgtctcgacctcaccatcgcgacc
gaggaccacaacaccccgacgctcgacatcgacaagcccatcgccgacccggtctcgcgc
gcccagctggagacgctgcgcaagaactgcgccgacttcggtgtgcgcctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtggtcggcccgcagctgggtctgacccagccc
ggtacgacggtcgtctgcggcgactcccacacctccacgcacggtgccttcggcgcgctg
gcgttcggcatcggcacctcccaggtggagcatgtgctcgccacccagacgctgccgctg
gcccgcccgaagaccatggccatcacggtcgacggcgaactgcccgacggcgtcacggcc
aaggacctgatcctggcgatcatcgcccggatcggcacgggcggcggccagggctacatc
ctggagtaccgcggctccgccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggtgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcgtacctcaagggccgcccgcacgcgcccgagggcgccgactgggacgccgcggtcgag
tactggaagacgctgcgcaccgacgacgacgccgagttcgacgccgaggtggtcatcgac
gcgagcgaactggcgccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcgtcctccgtccccgacccggcttcgtacgaagacgcttcggagcgcctcgccgccgaa
aaggccctggaatacatggggttggaggccgggcagccgctgcgcgccatcaaggtggac
accgtcttcgtaggctcgtgcaccaacggccgcatcgaggacctgcgtgccgcggccgag
atcgtcaagggccgcaaagtcgccgacggcgtacggatgctggtcgtcccgggctccgcg
cgcgtgggtctgcaggccgtctccgagggcctggacgtcgtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgtctgggcatgaaccccgaccagctggccccg
ggcgagcgctccgcgtccacctccaaccgcaacttcgagggcaggcagggcaagggcggt
cgtacgcacctggtgtccccgcaggtcgcggccgcgaccgcggtgacgggccacctggcc
tcgcccgccgacctgaccgacgcaaccgccgccgcgcccgctggagtctga
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